Molecule Details

Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)C(C)C
3-aminopyridine-like Enamine Mcule Assayed
View on Fragalysis x10327
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)C(C)C
MW: 302.805
Fraction sp3: 0.29
HBA: 2
HBD: 1
Rotatable Bonds: 4
TPSA: 41.99
cLogP: 4.42172
Covalent Warhead:
Covalent Fragment:
Source
Enamine Extended REAL: s_22____3391102____6586312
Mcule: MCULE-8180367507
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 21.338915
Average Inhibition @ 50 µM - Fluorescence: 42.4666
Average Inhibition @ 50 µM - RapidFire: 15.0033608685
Relative Solubility @ 20 µM: 0.99
Relative Solubility @ 100 µM: 0.99
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-06-10
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-4
0.677

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-4
0.677

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-5
0.677

View
Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

TRY-UNI-714a760b-18
0.677

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-5
0.677

View
Cc1ccncc1NC(=O)C(CO)c1cccc(Cl)c1

EDG-MED-0da5ad92-5
0.642

View
Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)N(C)C

JAN-GHE-83b26c96-10
0.623

View
Cc1ncncc1NC(=O)C(c1cccc(Cl)c1)C(C)C

JAN-GHE-83b26c96-7
0.609

View
CCCC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

JAN-GHE-83b26c96-8
0.597

View
Cc1ccncc1NC(=O)C(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-1
0.597

View
Cc1ccncc1NC(=O)C(C(=O)C(C)c1cccc(Cl)c1)c1cnccc1C

MAK-UNK-f203cb68-19
0.579

View
Cc1ccncc1NC(=O)CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-3
0.573

View
Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-3
0.551

View
Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

TRY-UNI-9f475305-3
0.551

View
Cc1ccncc1NC(=O)Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-4
0.543

View
CC(=O)Nc1cnccc1CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-1
0.531

View
Cc1ccncc1NC(=O)C(C)c1cncc(Cl)c1

TRY-UNI-2eddb1ff-3
0.529

View
Cc1ccncc1NC(=O)c1cc(C)c(NC(=O)C(C)c2cccc(Cl)c2)cn1

MAK-UNK-f203cb68-21
0.524

View
Cc1ccncc1NC(=O)C(C)c1ccccc1

AHN-SAT-202241f6-1
0.522

View
Cc1ccncc1NC(=O)C(C)c1ccccc1

TRY-UNI-714a760b-17
0.522

View
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

TRY-UNI-714a760b-12
0.522

View
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

JAG-UCB-cedd89ab-8
0.522

View
Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-10
0.521

View
Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1

JAN-GHE-83b26c96-22
0.521

View
Cc1ccncc1NC(=O)c1cncc(NC(=O)C(C)c2cccc(Cl)c2)c1C

MAK-UNK-f203cb68-22
0.518

View
Cc1ccncc1NC(=O)C(=O)c1cccc(Cl)c1

MAK-UNK-6ca90168-24
0.514

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.514

View
Cc1ccncc1NC(=O)N(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-3
0.507

View
Cc1ccncc1NC(=O)N(c1cccc(Cl)c1)c1cccc(Cl)c1

EDG-MED-0da5ad92-19
0.507

View
Cc1ccncc1NC(=O)C(C)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-18
0.500

View
COc1ccccc1OC[C@H](C(=O)Nc1cnccc1C)c1cccc(Cl)c1

ADA-UCB-6c2cb422-9
0.500

View
Cc1ccncc1NC(=O)c1nccc(C)c1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-20
0.488

View
CCC(O)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

BAR-COM-0f94fc3d-38
0.487

View
Cc1ccncc1NC(=O)C(F)(F)c1cccc(Cl)c1

JAN-GHE-83b26c96-23
0.486

View
Cc1ccncc1NC(=O)C(CO)c1ccccc1

BEN-DND-93268d01-3
0.486

View
CO[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-2
0.484

View
CO[C@H](C)C(=O)Nc1cnccc1C

ERI-UCB-5b47150d-1
0.484

View
CO[C@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-1
0.484

View
CC(C(=O)Nc1cnccc1Cl)c1cccc(Cl)c1

SAM-UNK-2684b532-7
0.479

View
Cc1ccncc1NC(=O)c1cc(Cl)cc(C(C)C(=O)Nc2cnccc2C)c1

MAK-UNK-f203cb68-16
0.474

View
Cc1ccncc1NC(=O)C(C)Cc1ccccc1

BEN-DND-93268d01-14
0.472

View
Cc1ccncc1NC(=N)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-6
0.472

View
Cc1ccncc1NC(=O)C(F)c1ccccc1

ABI-SAT-4d06482b-1
0.471

View
CC(C(=O)Nc1cnccc1C(F)(F)F)c1cccc(Cl)c1

SAM-UNK-2684b532-6
0.468

View
Cc1ccncc1NC(=O)C(C)c1cccc(C#N)c1

TRY-UNI-714a760b-22
0.468

View
CC(=O)N[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-13
0.463

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-11
0.463

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-12
0.463

View
Cc1ccncc1NC(=O)C(C(=O)c1cc(=O)[nH]c2ccccc12)c1cccc(Cl)c1

ALP-POS-ddb41b15-1
0.462

View
Cc1ccncc1NC(=O)N(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-2
0.462

View
Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC1

JAN-GHE-83b26c96-20
0.461

View
COc1cccc(C(O)C(=O)Nc2cnccc2C)c1

BAR-COM-0f94fc3d-19
0.461

View
Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC1

EDG-MED-0da5ad92-11
0.461

View
CC(=O)Nc1cnccc1C(C)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-9
0.458

View
Cc1ccncc1NC(=O)[C@H](C)OC(F)F

MAT-POS-590ac91e-16
0.456

View
CC(=O)Nc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

JAN-GHE-83b26c96-2
0.455

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-10
0.450

View
Cc1ccncc1NC(=O)c1ccc(Cl)cc1C(C)C(=O)Nc1cnccc1C

MAK-UNK-f203cb68-15
0.450

View
CC(C(=O)Nc1cnccc1C(F)F)c1cccc(Cl)c1

SAM-UNK-2684b532-5
0.449

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-13
0.444

View
Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC(=O)C1

BAR-COM-0f94fc3d-25
0.443

View
COCC(C(=O)Nc1cnccc1C)c1ccccc1

BEN-DND-93268d01-2
0.440

View
Cc1ccncc1NC(=O)c1ccc(C(C)C(=O)Nc2cnccc2C)cc1Cl

MAK-UNK-f203cb68-17
0.438

View
Cc1ccncc1NC(=O)C(C)CC1CC1

MAT-POS-590ac91e-5
0.437

View
CC(C(=O)Nc1cnccc1-n1cccn1)c1cccc(Cl)c1

JAN-GHE-83b26c96-3
0.434

View
CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.433

View
CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.433

View
Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.432

View
Cc1ccncc1NC(=O)c1c(Cl)cccc1C(C)C(=O)Nc1cnccc1C

MAK-UNK-f203cb68-14
0.432

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(C)C(N)=O)c1

WIL-MOD-03b86a88-3
0.432

View
Cc1ccncc1NC(=O)C1(Cc2cccc(Cl)c2)CCOCC1

SAD-SAT-7d5528d9-4
0.430

View
CC(=O)Nc1cnccc1-c1cc(Cl)cc(C(C)C(=O)Nc2cnccc2C)c1

MAK-UNK-f203cb68-7
0.430

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-15
0.429

View
CC(=O)Nc1cnccc1-c1cc(C)c(NC(=O)C(C)c2cccc(Cl)c2)cn1

MAK-UNK-f203cb68-12
0.427

View
CC(=O)Nc1cnccc1C(C(=O)C(C)c1cccc(Cl)c1)c1cnccc1C

MAK-UNK-f203cb68-10
0.425

View
Cc1ccncc1NC(=O)C(C)c1cc(Cl)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-8
0.425

View
Cc1ccncc1NS(=O)(=O)c1cccc(Cl)c1

JAN-GHE-83b26c96-21
0.425

View
CC(=O)Nc1cnccc1-c1ccc(Cl)cc1C(C)C(=O)Nc1cnccc1C

MAK-UNK-f203cb68-6
0.424

View
Cc1ccncc1NC(=O)N(Cc1ccccc1)c1cccc(Cl)c1

EDG-MED-0da5ad92-20
0.424

View
CC(=O)Nc1cnccc1Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-2
0.422

View
CC(=O)Nc1cnccc1-c1cncc(NC(=O)C(C)c2cccc(Cl)c2)c1C

MAK-UNK-f203cb68-13
0.420

View
Cc1ccncc1NC(=O)CC(C)C(C)C

MAT-POS-590ac91e-11
0.420

View
Cc1ccncc1NC(=O)[C@H](CNS(C)(=O)=O)c1ccc(Cl)cc1

DAN-RED-da448e80-9
0.420

View
Cc1ccncc1NC(=O)C(C)C1CCCCC1

TRY-UNI-714a760b-16
0.419

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.419

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.419

View
Cc1ccncc1NC(=O)C1CCN(Cc2cccc(Cl)c2)CC1

SAD-SAT-7d5528d9-7
0.419

View
Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.418

View
Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.415

View
CC(=O)Nc1cnccc1-c1nccc(C)c1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-11
0.413

View
Cc1ccncc1NC(=O)C(CNS(C)(=O)=O)c1ccccc1

DRE-WAB-eb790b7a-1
0.412

View
Cc1ccncc1NC(=O)[C@@H](CNS(C)(=O)=O)c1ccccc1

PED-UNI-8d53fd73-1
0.412

View
Cc1ccncc1NC(=O)[C@@H](CNS(C)(=O)=O)c1ccccc1

PED-UNI-5b7f1100-1
0.412

View
Cc1ccncc1NC(=O)[C@H](CNS(C)(=O)=O)c1ccccc1

DAN-RED-da448e80-1
0.412

View
CCC(C(=O)Nc1cnncc1C)c1cccc(Cl)c1

JAN-GHE-83b26c96-1
0.410

View
Cc1ccncc1NC(=O)[C@@H]1CC(=O)N(C)[C@@H]1c1cccc(Cl)c1

MAR-TRE-4b834d9a-26
0.409

View
Cc1ccncc1NC(=O)C(C#N)CC1CC1

MAT-POS-590ac91e-14
0.408

View
Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.408

View
COc1ccc(Br)cc1C(N)C(=O)Nc1cnccc1C

BAR-COM-0f94fc3d-58
0.407

View
Cc1nnc(N(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-4
0.407

View
CC1=CC=NC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

1.000

View
CC1=CN=CC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.692

View
CC(C)C(C(=O)NC1=CN=CC=C1O)C1=CC=CC(Cl)=C1

0.692

View
CC1=CN=NC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.688

View
CC1=CC=NC=C1NC(=O)C(C)C1=CC=CC(Cl)=C1

0.677

View
CC1=CC=NC=C1NC(=O)C(C1=CC=C(Cl)C=C1)C(C)C

0.656

View
COC1=CC=NC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.652

View
CC(C)C(C(=O)NC1=CC=NC=C1Br)C1=CC=CC(Cl)=C1

0.652

View
CC1=CC=NC=C1NC(=O)C(C1=CC=CC=C1)C(C)C

0.651

View
CC1=CC=NC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.641

View
CC(C)C(C(=O)NC1=CC=NC=C1F)C1=CC=CC(Cl)=C1

0.632

View
CC(C)C(C(=O)NC1=CC=NC=C1I)C1=CC=CC(Cl)=C1

0.632

View
CCC(C(=O)NC1=CN=CC=C1C)C1=CC=CC(Cl)=C1

0.623

View
CCC1=CN=CC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.623

View
CC1=CC=NC=C1NC(=O)C(C1=CC=CC(Cl)=C1)N(C)C

0.623

View
CC1=NC=NC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.609

View
CC1=CC=NC=C1NC(=O)NC(C)C1=CC=CC(Cl)=C1

0.600

View
CC1=CC=NC=C1NC(=O)C(C)CC1=CC=CC(Cl)=C1

0.600

View
CC(=O)NC1=CC=C(C)C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=C1

0.600

View
CCCC(C(=O)NC1=CN=CC=C1C)C1=CC=CC(Cl)=C1

0.597

View
CC1=NN=CC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.594

View
CC1=NC=C(C)C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=C1

0.586

View
CC1=CC=NC=C1C(C)NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.586

View
CC1=CC=C(S(C)(=O)=O)C=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.586

View
CC(C)C(C(=O)NC1=CC=NC=C1)C1=CC=CC(Cl)=C1

0.585

View
CC1=CN=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)N=C1

0.582

View
CC1=CC=C(O)C=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.580

View
CC1=NC=CC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.580

View
CC1=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)C=NN1C

0.580

View
CC1=CC=NC=C1NC(=O)C(OC1=CC=CC(Cl)=C1)C(C)C

0.577

View
CC1=CC(O)=CC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.574

View
CC(C)C(C(=O)NC1=CC=CN=C1)C1=CC=CC(Cl)=C1

0.574

View
CC(C)C(C(=O)NC1=CN=CC=N1)C1=CC=CC(Cl)=C1

0.574

View
CC(C)C(C(=O)NC1=CC=NC2=CC=NC=C12)C1=CC=CC(Cl)=C1

0.573

View
CC1=CC=C(N)C=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.571

View
CC1=CN=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)C(C)=C1

0.571

View
CC1=CC=NC=C1NC(=O)N(C)C(C)C1=CC=CC(Cl)=C1

0.569

View
CC1=CON=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.567

View
CC(C)C(C(=O)NC1=CC=CN=C1Cl)C1=CC=CC(Cl)=C1

0.565

View
CC1=CC=CN=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.565

View
CC1=CC=C(C(N)=O)C=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.563

View
CC1=CC=NC=C1NC(=O)C(C)OC1=CC=CC(Cl)=C1

0.563

View
CC1=CC=NC=C1CNC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.562

View
CC1=CC=NC=C1NC(=O)C(=O)NC(C)C1=CC=CC(Cl)=C1

0.562

View
CC1=CC=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)C(C)=N1

0.557

View
CC1=NN(C)C=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.557

View
CC(C)C(C(=O)NC1=CC=CN=C1O)C1=CC=CC(Cl)=C1

0.557

View
CC(=O)NC1=CC(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=CC=C1C

0.556

View
CC1=CC=NC=C1S(=O)(=O)NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.554

View
CNS(=O)(=O)C1=CC=C(C)C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=C1

0.554

View
CC1=CC(C)=NC(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=N1

0.552

View
CC(C)C(C(=O)NC1=CC=CC=C1O)C1=CC=CC(Cl)=C1

0.552

View
CC(=O)NC1=C(C)C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=CC=C1

0.551

View
CC1=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)N(C)N=C1

0.551

View
CC(C)C(C(=O)NC1=CC=CN=C1F)C1=CC=CC(Cl)=C1

0.549

View
CNC(=O)C1=CC=C(C)C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=C1

0.548

View
CC1=CC=NC=C1CCNC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.547

View
CC1=CC=NC=C1NC(=O)C(=O)N(C)C(C)C1=CC=CC(Cl)=C1

0.547

View
CC(C)C(C(=O)NC1=NC=CC=N1)C1=CC=CC(Cl)=C1

0.545

View
CC(C)C(C(=O)NC1=CN=CN=C1)C1=CC=CC(Cl)=C1

0.544

View
CC1=CC=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)N=C1

0.543

View
CC1=CC(C(N)=O)=CC=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.542

View
CC1=CC=NC=C1NC(=O)NC(C1=CC=CC=C1)C1=CC=CC(Cl)=C1

0.539

View
CC1=CC=C(S(=O)(=O)N(C)C)C=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.539

View
CC1=NC=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)C=N1

0.536

View
CC(C)C(C(=O)NC1=CC=CC=C1F)C1=CC=CC(Cl)=C1

0.536

View
CC1=CC(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=CN=C1

0.535

View
CC1=CC(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=CC=N1

0.535

View
CNC(=O)C1=CC=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)C(C)=C1

0.534

View
CC(C)C(C(=O)NC1=CC=NC(F)=C1F)C1=CC=CC(Cl)=C1

0.534

View
CC1=CC=C(C(=O)N(C)C)C=C1NC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.533

View
CC1=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)C=NN1CC(C)C

0.533

View
CC(C)C(C(=O)NC1=CC=NN=C1)C1=CC=CC(Cl)=C1

0.529

View
CC(C)C(C(=O)NC1=CC=C(F)N=C1F)C1=CC=CC(Cl)=C1

0.528

View
CC(C)C(C(=O)NC1=NC=CC2=CC=NC=C12)C1=CC=CC(Cl)=C1

0.526

View
CC1=CC=NC(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=C1

0.521

View
CC1=NC(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)=NC=C1

0.521

View
CC1=CC=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)C=N1

0.521

View
CC1=CN=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)[NH]1

0.521

View
CC1=CN=CC=C1CNC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.520

View
CC(C)C(C(=O)NNC1=CC=NC=C1Cl)C1=CC=CC(Cl)=C1

0.514

View
CC1=CC=C(NC(=O)C(C2=CC=CC(Cl)=C2)C(C)C)C(=O)N1C

0.514

View
CC1=CC=NC=C1NC(=O)C(=O)NCC(O)C1=CC=CC(Cl)=C1

0.513

View
CC1=CC(C(C)C(=O)NC2=CN=CC=C2C)=CC=C1

0.507

View
CC(C)C(C(=O)NC1=NC=CS1)C1=CC=CC(Cl)=C1

0.507

View
CC(C)C(C(=O)NC1=CN=NN1C)C1=CC=CC(Cl)=C1

0.507

View
CC1=CN=CC=C1CCNC(=O)C(C1=CC=CC(Cl)=C1)C(C)C

0.506

View
CC(C)C(C(=O)NC1=CC=C(F)N=C1)C1=CC=CC(Cl)=C1

0.493

View
CC1=CC(Cl)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.486

View
CC(C)C(C(=O)NNC1=CC=NC=C1)C1=CC=CC(Cl)=C1

0.486

View
CC1=CC=C(Cl)C=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.480

View
CC1=CN=CC=C1NC(=O)C(C)C1=CC=CC(Cl)=C1

0.473

View
CC1=CC(Cl)=NC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.461

View
CC(C)C(C(=O)NC1=CC=CC(Cl)=C1)C1=CC=CN=C1

0.459

View
CC1=C(Cl)C(NC(=O)C(C2=CC=CN=C2)C(C)C)=CC=C1

0.447

View
CC(C)C(C(=O)NC1=CC=C(Cl)C=C1Cl)C1=CC=CN=C1

0.440

View
CC1=CN=CC=C1NC(=O)C(C1=CC=C(Cl)C=C1)C(C)C

0.438

View
CC(C)C(C(=O)NC1=CC(Cl)=CC=C1Br)C1=CC=CN=C1

0.436

View
CC(C)C(C(=O)NC1=CC(Cl)=CC=C1Cl)C1=CC=CN=C1

0.429

View
CC1=C(C)C=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(Cl)=C1

0.429

View
CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

0.677

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

0.514

View
C(NC1=C(C)C=CN=C1)(=O)C(CC)C1=CC=CC=C1

0.833

View
C(NC1=CN=CC(Cl)=C1C)(=O)C(CC)C1=CC=CC=C1

0.805

View
C(NC1=C(C)C=CN=C1)(=O)C(C)C1=CC=C(Cl)C=C1

0.803

View
C(NC1=C(C)C=CN=C1)(=O)C(C1=CC=C(CC(C)C)C=C1)C

0.800

View
C(NC1=C(C)C=CN=C1)(=O)C(CC)C1=CC=C(Br)C=C1

0.783

View


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