Molecule Details

CCC(O)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1
3-aminopyridine-like Enamine Assayed
Molecular Properties
SMILES:
CCC(O)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1
MW: 304.1
Fraction sp3: 0.25
HBA: 3
HBD: 2
Rotatable Bonds: 4
TPSA: 62.22
cLogP: 3.28
Covalent Warhead:
Covalent Fragment:
Source
Enamine REAL: Z2002942936
Enamine Extended REAL: s_22____3391102____9823702
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 11.574052
Average Inhibition @ 50 µM - Fluorescence: 14.95138
Average Inhibition @ 50 µM - RapidFire: 7.88645824153136
Relative Solubility @ 20 µM: 0.99
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-05-30
Synthesis Location: enamine
Shipped: 2020-06-30
CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

View

Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-10
0.632

View
Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1

JAN-GHE-83b26c96-22
0.632

View
Cc1ccncc1NC(=O)C(C)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-18
0.632

View
Cc1ccncc1NC(=O)C(F)(F)c1cccc(Cl)c1

JAN-GHE-83b26c96-23
0.614

View
CC(=O)Nc1cnccc1C(C)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-9
0.531

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.493

View
Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)C(C)C

JAN-GHE-83b26c96-9
0.487

View
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

TRY-UNI-714a760b-12
0.479

View
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

JAG-UCB-cedd89ab-8
0.479

View
Cc1ccncc1NC(=O)C(=O)c1cccc(Cl)c1

MAK-UNK-6ca90168-24
0.473

View
Cc1ccncc1NC(=O)C(CO)c1cccc(Cl)c1

EDG-MED-0da5ad92-5
0.468

View
Cc1ccncc1NC(=O)CCc1cccc(Cl)c1

ALP-POS-f13221e1-4
0.468

View
Cc1ccncc1NC(=O)N(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-3
0.467

View
Cc1ccncc1NC(=O)N(c1cccc(Cl)c1)c1cccc(Cl)c1

EDG-MED-0da5ad92-19
0.467

View
CCCC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

JAN-GHE-83b26c96-8
0.457

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-4
0.455

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-4
0.455

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-5
0.455

View
Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

TRY-UNI-714a760b-18
0.455

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-5
0.455

View
Cc1ccncc1NC(=N)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-6
0.453

View
Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC1

JAN-GHE-83b26c96-20
0.443

View
Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC1

EDG-MED-0da5ad92-11
0.443

View
Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)N(C)C

JAN-GHE-83b26c96-10
0.438

View
COC(=O)C(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAT-POS-1e5f28a7-1
0.432

View
Cc1ccncc1NC(=O)N(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-2
0.427

View
Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC(=O)C1

BAR-COM-0f94fc3d-25
0.427

View
Cc1ccncc1NC(=O)CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-3
0.424

View
Cc1ccncc1NC(=O)N(CCC1CCCCC1)c1cccc(Cl)c1

MAT-POS-136e7878-1
0.422

View
CCC(F)(F)c1cccc(CC(=O)Nc2cnccc2C)c1

DAR-DIA-0cde14eb-77
0.422

View
Cc1ccncc1NC(=O)C(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-1
0.422

View
Cc1ccncc1NC(=O)C1CCN(Cc2cccc(Cl)c2)CC1

SAD-SAT-7d5528d9-7
0.420

View
Cc1ccncc1NC(=O)Cc1cccc(C(C)(F)F)c1

DAR-DIA-0cde14eb-79
0.420

View
Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.418

View
Cc1ccncc1NC(=O)C1(Cc2cccc(Cl)c2)CCOCC1

SAD-SAT-7d5528d9-4
0.416

View
CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.413

View
CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.413

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
0.412

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

DAR-DIA-0cde14eb-76
0.412

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

JAN-GHE-83b26c96-14
0.412

View
CC(=O)Nc1cnccc1CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-1
0.411

View
CC(=O)N1CCN(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)CC1

VLA-UCB-05e51b3f-2
0.409

View
Cc1ccncc1NC(=O)N(Cc1ccccc1)c1cccc(Cl)c1

EDG-MED-0da5ad92-20
0.409

View
Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-3
0.409

View
Cc1nnc(N(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-4
0.409

View
Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

TRY-UNI-9f475305-3
0.409

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.403

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.403

View
Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.400

View
Cc1ccncc1NC(=O)C(C(=O)C(C)c1cccc(Cl)c1)c1cnccc1C

MAK-UNK-f203cb68-19
0.398

View
Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.397

View
Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.397

View
Cc1ccncc1NC(=O)CC(C)(C)c1ccccc1

BEN-DND-93268d01-13
0.397

View
Cc1ccncc1NC(=O)[C@@H]1CC(=O)N(C)[C@@H]1c1cccc(Cl)c1

MAR-TRE-4b834d9a-26
0.396

View
Cc1ccncc1NC(=O)Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-4
0.391

View
Cc1ccncc1NS(=O)(=O)c1cccc(Cl)c1

JAN-GHE-83b26c96-21
0.390

View
COc1ccccc1OC[C@H](C(=O)Nc1cnccc1C)c1cccc(Cl)c1

ADA-UCB-6c2cb422-9
0.389

View
Cc1ccncc1NC(=O)Cn1ccc2ccc(Cl)cc21

BAR-COM-0f94fc3d-41
0.388

View
Cc1ccncc1NS(=O)(=O)Cc1cccc(Cl)c1

JAN-GHE-83b26c96-17
0.388

View
Cc1ccncc1NC(=O)c1cncc(NC(=O)C(C)c2cccc(Cl)c2)c1C

MAK-UNK-f203cb68-22
0.387

View
Cc1ccncc1OCCNC(=O)C(C)(C)c1cccc(Cl)c1

WIL-UNI-2e73223c-4
0.386

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(N)=O)c1

RAL-THA-6b94ceba-6
0.386

View
C=CC(=O)Nc1cnccc1C

MAK-UNK-6ca90168-27
0.382

View
Cc1ccncc1NC(=O)[C@@H]1C[C@H]1CF

ERI-UCB-5b47150d-6
0.382

View
Cc1ccncc1CC(=O)Nc1cccc(Cl)c1

EDJ-MED-49816e9b-1
0.380

View
Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.380

View
COc1cc(Cl)cc(OC(=O)Nc2cnccc2C)c1

MAT-POS-0d6fb2dd-1
0.378

View
COc1cc(Cl)cc(OC(=O)Nc2cnccc2C)c1

MAT-POS-6c3d76b3-1
0.378

View
Cc1ccncc1NC(=O)CN1CCCCC1

BEN-DND-93268d01-11
0.377

View
Cc1ccncc1NC(=O)CN1CCN(C)CC1

BEN-DND-93268d01-9
0.377

View
Cc1ccncc1NC(=O)c1cc(C)c(NC(=O)C(C)c2cccc(Cl)c2)cn1

MAK-UNK-f203cb68-21
0.376

View
Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.375

View
CCCCOc1ccc(Cl)cc1CC(=O)Nc1cnccc1C

EDG-MED-0da5ad92-7
0.375

View
Cc1ccncc1NC(=O)C(C)c1cncc(Cl)c1

TRY-UNI-2eddb1ff-3
0.375

View
Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.375

View
Cc1ccncc1NC(=O)CCc1nc2cc(Cl)ccc2o1

GAB-REV-70cc3ca5-22
0.374

View
Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.373

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CS(N)(=O)=O)c1

RAL-THA-6b94ceba-15
0.372

View
CC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-5
0.372

View
COc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

MAT-POS-c9973a83-1
0.369

View
CNS(=O)(=O)Cc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-16
0.368

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(C)(=O)=O)c1

WIL-MOD-03b86a88-5
0.368

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CNS(C)(=O)=O)c1

RAL-THA-6b94ceba-12
0.368

View
CNS(=O)(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-14
0.368

View
CCO[C@@H]1C[C@H]1C(=O)Nc1cnccc1C

MAT-POS-590ac91e-8
0.367

View
Cc1ccncc1NC(=O)NCCCC(N)N

ALE-HEI-f28a35b5-11
0.367

View
COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.366

View
CC(=O)N[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-13
0.365

View
Cc1ccncc1NC(=O)CC(C)C(C)C

MAT-POS-590ac91e-11
0.365

View
Cc1ccncc1NC(=O)NCCBr

ALE-HEI-f28a35b5-13
0.365

View
Cc1ccncc1NC(=O)CCCBr

ALE-HEI-f28a35b5-12
0.365

View
Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

ANN-UNI-98d2bf15-5
0.365

View
Cc1ccncc1NC(=O)c1nccc(C)c1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-20
0.365

View
COC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-8
0.364

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2nnc[nH]2)c1

RAL-THA-6b94ceba-10
0.363

View
Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

ANN-UNI-98d2bf15-2
0.361

View
CO[C@H](C)C(=O)Nc1cnccc1C

ERI-UCB-5b47150d-1
0.361

View
CO[C@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-1
0.361

View
CO[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-2
0.361

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(S(N)(=O)=O)c1

RAL-THA-6b94ceba-13
0.360

View
CCC(O)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

1.000

View
CCC(O)(C(=O)Nc1ccncc1C)c1cccc(Cl)c1

0.840

View
CCC(O)(C(=O)Nc1cnccc1O)c1cccc(Cl)c1

0.820

View
CCC(O)(C(=O)Nc1cnccc1OC)c1cccc(Cl)c1

0.759

View
CCC(O)(C(=O)Nc1cnccc1C)c1ccccc1

0.755

View
CCC(O)(C(=O)Nc1ccncc1I)c1cccc(Cl)c1

0.755

View
CCC(O)(C(=O)Nc1ccccc1C)c1cccc(Cl)c1

0.740

View
CCC(O)(C(=O)Nc1cc(Cl)ccc1C)c1cccc(Cl)c1

0.740

View
CCC(O)(C(=O)Nc1cc(-c2cccnc2)ccc1C)c1cccc(Cl)c1

0.737

View
CCC(O)(C(=O)Nc1cnc(Cl)cc1C)c1cccc(Cl)c1

0.736

View
CCC(O)(C(=O)Nc1ccnc2ccncc12)c1cccc(Cl)c1

0.714

View
CCC(O)(C(=O)Nc1cc(C)ccc1C)c1cccc(Cl)c1

0.712

View
CCC(O)(C(=O)Nc1cnc(Br)cc1C)c1cccc(Cl)c1

0.709

View
CCC(O)(C(=O)NCc1cnccc1C)c1cccc(Cl)c1

0.709

View
Cc1ccncc1NC(=O)NCC(C)(O)c1cccc(Cl)c1

0.709

View
CCC(O)(C(=O)Nc1ccc(Cl)cc1C)c1cccc(Cl)c1

0.706

View
Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1

0.706

View
CCC(O)(C(=O)Nc1ccncc1)c1cccc(Cl)c1

0.706

View
CCC(O)(C(=O)Nc1cccnc1)c1cccc(Cl)c1

0.698

View
CCC(O)(C(=O)Nc1ccc(O)cc1C)c1cccc(Cl)c1

0.698

View
CCC(O)(C(=O)Nc1cccc(C)c1C)c1cccc(Cl)c1

0.692

View
Cc1ccncc1NC(=O)C(F)(F)c1cccc(Cl)c1

0.692

View
CCC(O)(C(=O)Nc1cscc1C)c1cccc(Cl)c1

0.692

View
CCC(O)(C(=O)Nc1cncc2ccccc12)c1cccc(Cl)c1

0.691

View
CCC(O)(C(=O)Nc1cc(-c2ccnn2C)ccc1C)c1cccc(Cl)c1

0.690

View
CCC(O)(C(=O)Nc1cc(F)ccc1C)c1cccc(Cl)c1

0.685

View
CCC(O)(C(=O)Nc1cccnc1C)c1cccc(Cl)c1

0.685

View
CCC(O)(C(=O)Nc1cnn(C)c1C)c1cccc(Cl)c1

0.685

View
CCC(O)(C(=O)NCCc1cnccc1C)c1cccc(Cl)c1

0.684

View
CCC(O)(C(=O)NC(C)c1cnccc1C)c1cccc(Cl)c1

0.684

View
CCC(O)(C(=O)Nc1ccc(C)cc1C)c1cccc(Cl)c1

0.679

View
CCC(O)(C(=O)Nc1cnc(C)nc1)c1cccc(Cl)c1

0.679

View
CCC(O)(C(=O)Nc1cc(Cl)cc(C)c1O)c1cccc(Cl)c1

0.679

View
CCC(O)(C(=O)Nc1cccc(C)c1O)c1cccc(Cl)c1

0.679

View
CCC(O)(C(=O)NCc1ccncc1C)c1cccc(Cl)c1

0.679

View
Cc1ccncc1NC(=O)C(=O)NCC(C)(O)c1cccc(Cl)c1

0.679

View
CCC(O)(C(=O)Nc1cncnc1)c1cccc(Cl)c1

0.673

View
CCC(O)(C(=O)Nc1cc(C(F)(F)F)ccc1C)c1cccc(Cl)c1

0.673

View
CCC(O)(C(=O)Nc1cc(C(C)=O)ccc1C)c1cccc(Cl)c1

0.673

View
CCC(O)(C(=O)Nc1cnc(C)nc1C)c1cccc(Cl)c1

0.673

View
CCC(O)(C(=O)NNc1ccncc1Cl)c1cccc(Cl)c1

0.673

View
CCC(O)(C(=O)Nc1ccnc(C)c1Cl)c1cccc(Cl)c1

0.673

View
CCC(O)(C(=O)Nc1ccc(C)c(NC(=O)c2ccncc2)c1)c1cccc(Cl)c1

0.667

View
CCC(O)(C(=O)Nc1cc(O)c(C)cc1C)c1cccc(Cl)c1

0.667

View
CCC(O)(C(=O)Nc1cc(C(N)=O)ccc1C)c1cccc(Cl)c1

0.661

View
CCC(O)(C(=O)Nc1cc(NC(C)=O)ccc1C)c1cccc(Cl)c1

0.661

View
CCC(O)(C(=O)Nc1ccc(F)nc1C)c1cccc(Cl)c1

0.661

View
CCC(O)(C(=O)Nc1cc(SC)ccc1C)c1cccc(Cl)c1

0.661

View
CCC(O)(C(=O)Nc1cccc(Cl)c1C)c1cccc(Cl)c1

0.660

View
CCC(O)(C(=O)NCCc1ccncc1C)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1nccc2ccncc12)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1ccc(F)cc1C)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1ccc(C)c(O)c1C)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1ccc(C)nc1C)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1cccnc1O)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1cncc(C)c1)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1c(C)cnn1C)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1ccc(Cl)nc1C)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1cc(C)c(O)c(C)c1C)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1cn(C)nc1C)c1cccc(Cl)c1

0.655

View
CCC(O)(C(=O)Nc1ccccc1Cl)c1cccc(Cl)c1

0.654

View
CCC(O)(C(=O)Nc1ccccc1O)c1cccc(Cl)c1

0.654

View
CCC(O)(C(=O)Nc1cc(Cl)ccc1O)c1cccc(Cl)c1

0.654

View
CCC(O)(C(=O)Nc1cc(C(=O)OC)ccc1C)c1cccc(Cl)c1

0.649

View
CCNC(=O)c1ccc(C)c(NC(=O)C(O)(CC)c2cccc(Cl)c2)c1

0.649

View
CCC(O)(C(=O)Nc1ccc(C)c(NC(=O)C(C)(C)C)c1)c1cccc(Cl)c1

0.649

View
CCC(O)(C(=O)Nc1cc(Br)cnc1C)c1cccc(Cl)c1

0.649

View
CCC(O)(C(=O)Nc1cc(F)ncc1OC)c1cccc(Cl)c1

0.649

View
CCC(O)(C(=O)Nc1ccc(C)cc1Cl)c1cccc(Cl)c1

0.648

View
CCC(O)(C(=O)Nc1cc(C)ccc1Cl)c1cccc(Cl)c1

0.648

View
CCC(O)(C(=O)Nc1cc(C)ccc1O)c1cccc(Cl)c1

0.648

View
CCC(O)(C(=O)Nc1cccc(NC(C)=O)c1C)c1cccc(Cl)c1

0.648

View
CCC(O)(C(=O)Nc1ccsc1Cl)c1cccc(Cl)c1

0.648

View
CCC(O)(C(=O)Nc1ccc(C)c2ncccc12)c1cccc(Cl)c1

0.644

View
CCC(O)(C(=O)Nc1ccc(C)c2cn[nH]c12)c1cccc(Cl)c1

0.644

View
CCC(O)(C(=O)Nc1ccc(-c2ccncc2)c(C)c1)c1cccc(Cl)c1

0.644

View
CCC(C)n1ncc(NC(=O)C(O)(CC)c2cccc(Cl)c2)c1C

0.644

View
CCC(O)(C(=O)Nc1cc2cn[nH]c2cc1C)c1cccc(Cl)c1

0.644

View
CCC(O)(C(=O)Nc1ccc(OC)cc1C)c1cccc(Cl)c1

0.643

View
CCC(O)(C(=O)Nc1cnc(Cl)c(C)c1)c1cccc(Cl)c1

0.643

View
CCC(O)(C(=O)Nc1ccc(C)nc1O)c1cccc(Cl)c1

0.643

View
CCC(O)(C(=O)Nc1cc(CO)c(C)cc1C)c1cccc(Cl)c1

0.643

View
CCC(O)(C(=O)Nc1csnc1C)c1cccc(Cl)c1

0.643

View
CCc1c(NC(=O)C(O)(CC)c2cccc(Cl)c2)cnn1C

0.643

View
Cc1ccncc1NC(=O)NCC(C)(C)c1cccc(Cl)c1

0.643

View
CCC(O)(C(=O)Nc1cccc(F)c1F)c1cccc(Cl)c1

0.642

View
CCC(O)(C(=O)Nc1cccc(Cl)c1O)c1cccc(Cl)c1

0.642

View
CCC(O)(C(=O)Nc1ccc(Cl)cc1O)c1cccc(Cl)c1

0.642

View
CCC(O)(C(=O)Nc1cc(-c2ncc[nH]2)ccc1C)c1cccc(Cl)c1

0.639

View
CCC(O)(C(=O)Nc1cc(CN(C)C)ccc1C)c1cccc(Cl)c1

0.638

View
CCC(O)(C(=O)Nc1cnn(-c2cccc(Cl)c2)c1C)c1cccc(Cl)c1

0.638

View
CCNC(=O)Nc1ccc(C)c(NC(=O)C(O)(CC)c2cccc(Cl)c2)c1

0.638

View
CCC(O)(C(=O)Nc1cc(NC(=O)N(C)C)ccc1C)c1cccc(Cl)c1

0.638

View
CCC(O)(C(=O)Nc1cccc(F)c1C)c1cccc(Cl)c1

0.636

View
CCC(O)(C(=O)Nc1cccc(I)c1C)c1cccc(Cl)c1

0.636

View
CCC(O)(C(=O)Nc1cnnn1C)c1cccc(Cl)c1

0.636

View
CCC(O)(C(=O)Nc1nccn1C)c1cccc(Cl)c1

0.636

View
CCC(O)(C(=O)Nc1nn(C)cc1C)c1cccc(Cl)c1

0.636

View
CCC(O)(C(=O)Nc1ccc(C)cc1O)c1cccc(Cl)c1

0.636

View
CCC(O)(C(=O)Nc1nnc(C)n1C)c1cccc(Cl)c1

0.636

View

C(NC1=C(C)C=CN=C1)(=O)C(CC)C1=CC=CC=C1

0.751

View
C(NC1=CN=CC(Cl)=C1C)(=O)C(CC)C1=CC=CC=C1

0.733

View
C(NC1=C(C)C=CN=C1)(=O)C(C)C1=CC=C(Cl)C=C1

0.725

View
C(NC1=C(C)C=CN=C1)(=O)C(CC)C1=CC=C(Br)C=C1

0.713

View


Discussion: