Molecule Details

Cc1ccncc1NC(=O)Cc1cccc(Cl)c1
3-aminopyridine-like Enamine Mcule MolPort Assayed
View on Fragalysis x2646
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1
MW: 260.724
Fraction sp3: 0.14
HBA: 2
HBD: 1
Rotatable Bonds: 3
TPSA: 41.99
cLogP: 3.22462
Covalent Warhead:
Covalent Fragment: ✔️
Source
Enamine SCR: Z1129289650
Enamine REAL: Z1129289650
Enamine Extended REAL: s_22____3391102____3020518
Mcule: MCULE-6726698643
Mcule Ultimate: ZROFBWFSOGSOQG-UHFFFAOYSA-N
MolPort: MolPort-047-314-768
Activity Data
IC50 (µM) - Fluorescence: 24.5666191954425
IC50 (µM) - RapidFire: 13.8951649217851
Trypsin IC50 (µM): 99.0
pIC50 (µM) - Fluorescence 4.60965460606728
Average Inhibition @ 20 µM - Fluorescence: 61.634345
Average Inhibition @ 50 µM - Fluorescence: 81.75696
Average Inhibition @ 20 µM - RapidFire: 20.0252393
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-03-31
Synthesis Location: enamine
Shipped: 2020-04-09
Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.700

View
Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.700

View
Cc1ccncc1NC(=N)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-6
0.700

View
Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.700

View
Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.689

View
Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.689

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

ALP-POS-95b75b4d-8
0.667

View
COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.667

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

SAM-UNK-2684b532-13
0.667

View
Cc1ccncc1NC(=O)Cc1cccc(C(C)(F)F)c1

DAR-DIA-0cde14eb-79
0.662

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

JAN-GHE-83b26c96-14
0.656

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
0.656

View
Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

ANN-UNI-98d2bf15-2
0.656

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

DAR-DIA-0cde14eb-76
0.656

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.656

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.656

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1O

ALP-POS-95b75b4d-6
0.656

View
Cc1ccncc1NC(=O)Cc1cccc(C#N)c1

TRY-UNI-714a760b-20
0.646

View
Cc1ccncc1NC(=O)Cc1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-2
0.642

View
Cc1cnncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-16
0.639

View
Cc1ccncc1NC(=O)Cc1cccc([S+](C)[O-])c1

DAR-DIA-0cde14eb-78
0.636

View
Cc1ccncc1NC(=O)Cc1cccc(S(N)(=O)=O)c1

EDJ-MED-e58735b6-3
0.636

View
Cc1ccncc1NC(=O)Cc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-3
0.632

View
Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.627

View
Cc1ccncc1NC(=O)Cc1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-1
0.627

View
Cc1ccncc1NC(=O)Cc1cccc(C2CC2)c1

ALP-POS-95b75b4d-4
0.627

View
Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

ANN-UNI-98d2bf15-5
0.627

View
NC(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

ANN-UNI-98d2bf15-3
0.625

View
Cc1cncc(NC(=O)Cc2cccc(Cl)c2)c1C

PET-UNK-8df914d1-3
0.619

View
N#Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

MAK-UNK-6ca90168-23
0.615

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C1CC1

ALP-POS-95b75b4d-5
0.612

View
Cc1ccncc1NC(=O)Cc1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-4
0.609

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CCC(F)(F)c1cccc(CC(=O)Nc2cnccc2C)c1

DAR-DIA-0cde14eb-77
0.609

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)(F)F

SAM-UNK-2684b532-12
0.606

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)F

SAM-UNK-2684b532-11
0.606

View
Cc1cc(N)ncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-17
0.600

View
NS(=O)(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

ALP-POS-95b75b4d-7
0.597

View
O=C(Cc1cccc(Cl)c1)Nc1cncc(Cl)c1Cl

JAN-GHE-5a013bed-10
0.597

View
Cc1ccncc1NC(=O)Cc1cccc(-c2cn[nH]c2)c1

EDJ-MED-e58735b6-4
0.592

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(N)=O)c1

RAL-THA-6b94ceba-6
0.588

View
COc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

MAT-POS-c9973a83-1
0.588

View
Cc1ncncc1NC(=O)Cc1cccc(Cl)c1

ABI-SAT-4d06482b-2
0.585

View
Cc1ccncc1NC(=O)Cc1cccc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-14
0.583

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1-c1ccccc1

ALP-POS-0c2c77e1-1
0.580

View
CNS(=O)(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-14
0.577

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Cc1c(N)cncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-3
0.576

View
Cc1ccncc1NC(=O)Cc1cccc(CN2CCOCC2)c1

SAD-SAT-7d5528d9-1
0.575

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Cc1ccc(CC(=O)Nc2cnccc2C)cc1

JAN-GHE-83b26c96-11
0.574

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(S(N)(=O)=O)c1

RAL-THA-6b94ceba-13
0.571

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CNC(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-7
0.571

View
Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.571

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

BRU-LEF-c49414a7-1
0.568

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Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-7
0.568

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CS(N)(=O)=O)c1

RAL-THA-6b94ceba-15
0.563

View
CC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-5
0.563

View
Cc1[nH]ncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-21
0.562

View
CNS(=O)(=O)Cc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-16
0.556

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CNS(C)(=O)=O)c1

RAL-THA-6b94ceba-12
0.556

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(C)C(N)=O)c1

WIL-MOD-03b86a88-3
0.556

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(C)(=O)=O)c1

WIL-MOD-03b86a88-5
0.556

View
Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-14
0.554

View
Cc1ccncc1NC(=O)Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-4
0.551

View
COC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-8
0.548

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(N)(=O)=O)c1

WIL-MOD-03b86a88-6
0.548

View
Cc1ccncc1NC(=O)Cc1ccsc1

MIH-UNI-6b9ca91a-1
0.547

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2ncc[nH]2)c1

RAL-THA-6b94ceba-9
0.541

View
Cc1ccncc1NC(=O)CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-3
0.541

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C2COC2)c1

WIL-MOD-03b86a88-2
0.541

View
Cc1ccnc(C)c1NC(=O)Cc1cccc(Cl)c1

EDJ-MED-49816e9b-2
0.538

View
Cc1ccnc(N)c1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-18
0.537

View
Cc1ccncc1NC(=O)C(CO)c1cccc(Cl)c1

EDG-MED-0da5ad92-5
0.536

View
Cc1ccncc1NC(=O)Cc1ccc2nc[nH]c2c1

GAB-REV-70cc3ca5-18
0.534

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2cnc[nH]2)c1

RAL-THA-6b94ceba-11
0.533

View
O=C(Cc1cccc(Cl)c1)Nc1cccnc1

EDG-MED-0da5ad92-2
0.531

View
O=C(Cc1cccc(Cl)c1)Nc1cnccn1

JAN-GHE-5a013bed-8
0.531

View
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

TRY-UNI-714a760b-12
0.530

View
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

JAG-UCB-cedd89ab-8
0.530

View
Cc1ccncc1NC(=O)Cc1ccccc1N

ANN-UNI-98d2bf15-1
0.530

View
Cc1ccncc1N(C)C(=O)Cc1cccc(Cl)c1

JAN-GHE-83b26c96-15
0.529

View
Cc1ccncc1N(C)C(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-1
0.529

View
Cc1ccncc1NC(=O)Cc1ccc2[nH]ncc2c1

VLA-UCB-00f2c2b3-2
0.528

View
Cc1ccncc1NC(=O)Cc1ccc(S(N)(=O)=O)cc1

GAB-REV-70cc3ca5-20
0.522

View
Cc1ccncc1NC(=O)C(=O)c1cccc(Cl)c1

MAK-UNK-6ca90168-24
0.522

View
Cc1ccnnc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-15
0.522

View
Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

TRY-UNI-714a760b-18
0.522

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-4
0.522

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-5
0.522

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-4
0.522

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-5
0.522

View
Cc1ccncc1NC(=O)Cc1ccc2[nH]ccc2c1

VLA-UCB-00f2c2b3-1
0.521

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2nnc[nH]2)c1

RAL-THA-6b94ceba-10
0.519

View
Cc1cc(CC(=O)Nc2cnccc2C)[nH]n1

EDJ-MED-c9f55a56-1
0.515

View
Cc1ccncc1NC(=O)N(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-3
0.515

View
Cc1ccncc1NC(=O)N(c1cccc(Cl)c1)c1cccc(Cl)c1

EDG-MED-0da5ad92-19
0.515

View
Cc1ccncc1NC(=O)Cc1cncc(C#N)c1

TRY-UNI-2eddb1ff-1
0.514

View
Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)C(C)C

JAN-GHE-83b26c96-9
0.514

View
Cc1ccncc1NC(=O)C(F)(F)c1cccc(Cl)c1

JAN-GHE-83b26c96-23
0.514

View
Cc1ccncc1NC(=O)Cc1cc(Cl)c2c(c1)OCCO2

BAR-COM-0f94fc3d-28
0.513

View
Cc1ccncc1NC(=O)C1CCN(Cc2cccc(Cl)c2)CC1

SAD-SAT-7d5528d9-7
0.513

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OC2COC2)c1

WIL-MOD-03b86a88-4
0.513

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

1.000

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2=CC=CC(Cl)=C2)=C1

0.714

View
CC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.712

View
CC1=CC=NC=C1NC(=O)CCC1=CC=CC(Cl)=C1

0.710

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(I)=C1

0.700

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Br)=C1

0.689

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(F)=C1

0.689

View
CC1=CN=CC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.672

View
COC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.667

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1C

0.661

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.656

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC([N+](=O)[O-])=C1

0.656

View
O=C(CC1=CC=CC(Cl)=C1)NC1=CN=CC=C1O

0.656

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C(Cl)=C1

0.656

View
COC(=O)C1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.646

View
COCC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.646

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)F)=C1

0.646

View
CC1=CC=NC=C1NC(=O)CSCC1=CC=CC(Cl)=C1

0.642

View
CC(=O)NC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.641

View
CC1=CN=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.639

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1O

0.639

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1Br

0.639

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2=CC=C(Cl)C=C2)=C1

0.639

View
CC1=CC=NC=C1NC(=O)CC1=CC(OC(C)C)=CC=C1

0.636

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C=C1

0.633

View
COC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.631

View
CSC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.631

View
CC1=CC=NC=C1NC(=O)CC1=CC=CN=C1

0.627

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(C2CC2)=C1

0.627

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OC(F)(F)F)=C1

0.627

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(NS(C)(=O)=O)=C1

0.627

View
CCS(=O)(=O)C1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.627

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OC(F)F)=C1

0.627

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.625

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Br)C(Cl)=C1

0.625

View
CCC1=CN=CC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.619

View
CC1=CC(Cl)=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.619

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(F)C(F)=C1

0.619

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=NC=C1Br

0.613

View
O=C(CC1=CC=CC(Cl)=C1)NC1=CC=NC=C1O

0.613

View
CC1=CC(Br)=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.609

View
CCCOC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.609

View
CC1=CC=NC=C1NC(=O)CC1=CSC(CC2=CC=CC(Cl)=C2)=N1

0.605

View
CC(C)(C)OC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.603

View
CC1=CC=CC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.600

View
COCCOC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.600

View
CC1=CC=NC=C1NC(=O)NCC1=CC=CC(Cl)=C1

0.597

View
O=C(CC1=CC=CC(Cl)=C1)NC1=CC=NC=C1F

0.594

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=NC=C1I

0.594

View
CC1=CC=NC=C1NC(=O)CC1=CC=NC=C1

0.593

View
CC1=NC=CN1C1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.592

View
CNC(=O)COC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.592

View
CC(=O)C1=CN=CC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.591

View
CC1=CC=NC=C1NC(=O)CNC1=CC=CC(Cl)=C1

0.591

View
CC1=CC=C(Cl)C=C1NC(=O)CC1=CC=CC(Cl)=C1

0.590

View
CC1=CC(C)=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.590

View
CC1=CC(Cl)=CC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.590

View
CC1=CC=NC=C1NC(=O)C(C)(C)CC1=CC=CC(Cl)=C1

0.588

View
CC1=CC=NC=C1NC(=O)C(=O)NCC1=CC=CC(Cl)=C1

0.588

View
CC1=CC=NC=C1NC(=O)C(C)CC1=CC=CC(Cl)=C1

0.588

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC=C1Cl

0.588

View
CC1=CC=NC=C1NC(=O)CC1=C(Cl)C=CC=C1Cl

0.587

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)N=C1

0.587

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C=C1Cl

0.585

View
CC1=CC=NC=C1NC(=O)CC1=C(Cl)C(C)=CC=C1

0.585

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(NC(=O)OC(C)(C)C)=C1

0.583

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2C=CC=CC2=C1

0.582

View
CC1=CC=NC=C1NC(=O)COC1=CC=CC(Cl)=C1

0.582

View
CC1=CC=C(C)C(NC(=O)CC2=CC=CC(Cl)=C2)=C1

0.581

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CN=CC=C1C1=CC=CC=C1

0.580

View
CC1=CC=NC=C1NC(=O)N(C)CC1=CC=CC(Cl)=C1

0.580

View
CC1=CC=NC=C1NC(=O)NCCC1=CC=CC(Cl)=C1

0.580

View
CC1=CC=NC=C1NC(=O)C(=O)NCCC1=CC=CC(Cl)=C1

0.580

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2=CC=CC=C2Cl)=C1

0.579

View
CC1=CC=C(C2=CC=CN=C2)C=C1NC(=O)CC1=CC=CC(Cl)=C1

0.577

View
CC1=CC=NC=C1NC(=O)CC1=CC(Cl)=CC=C1Cl

0.576

View
CC1=CN(C2=CC=NC=C2NC(=O)CC2=CC=CC(Cl)=C2)N=C1

0.575

View
CN1CCN(C2=CC=NC=C2NC(=O)CC2=CC=CC(Cl)=C2)CC1

0.575

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.574

View
CC1=CC=NC=C1NC(=O)CC1=CN=CN=C1

0.574

View
CC1=CC(C(F)(F)F)=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.574

View
CC(C)C(=O)C1=CN=CC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.574

View
CC1=CC=NC=C1NC(=O)CNC(=O)C1=CC=CC(Cl)=C1

0.574

View
CC1=CC=C(C2=CC=NC=C2)C=C1NC(=O)CC1=CC=CC(Cl)=C1

0.571

View
CC1=CC=NC=C1NC(=O)C(=O)N1CCN(C(=O)CC2=CC=CC(Cl)=C2)CC1

0.571

View
CC1=CC=NC=C1NC(=O)CCSC1=CC=CC(Cl)=C1

0.571

View
CC1=CC=NC=C1NC(=O)CC1=C(Cl)C=CC=C1C

0.569

View
CC1=CC(NC(=O)CC2=CC=CC(Cl)=C2)=C(C)C=N1

0.569

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC2=CC=CN=C2)=C1

0.568

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C=C1Br

0.567

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=CC2=CC=NC=C12

0.565

View
CC1=CC=NC=C1NC(=O)CC1=C(C)C=CC=C1C

0.565

View
CC1=CC=NC=C1NC(=O)C(=O)N(C)CC1=CC=CC(Cl)=C1

0.563

View
N#CC1=CN=CC=C1NC(=O)CC1=CC(Cl)=CC=C1

0.559

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=CC2=CN=CC=C12

0.557

View
CC1=CC(C)=C(CC(=O)NC2=CN=CC=C2C)C(C)=C1

0.531

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=NC2=CC=NC=C12

0.528

View
CC1=CC=NC=C1NC(=O)N(CCN(C)C)CC1=CC=CC(Cl)=C1

0.526

View
CC1=CN=CC=C1NC(=O)CC1=CC=CC(OCC2=CC=CC(Cl)=C2)=C1

0.500

View
CC1=CC=C(Cl)C=C1NC(=O)CC1=CC=CN=C1

0.478

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

1.000

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)cc1

0.633

View
Cc1ccncc1NC(=O)Cc1ccccc1

0.627

View
Cc1ccncc1NC(=O)Cc1ccc(F)cc1

0.556

View
CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

0.522

View
CC(C(=O)Nc1cnccc1C)c1ccccc1

0.380

View
Clc1ccc(CC(=O)Nc2cccnc2)cc1Cl

0.324

View
Clc1ccc(CC(=O)Nc2cccnc2)cc1

0.306

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=CC(Cl)=C1

1.000

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=C(Cl)C=C1

0.946

View
C(NC1=C(C)C=CN=C1)(=O)CC1=C(Cl)C=CC=C1

0.917

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1=CC=CC(Cl)=C1

0.909

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=C(F)C(Cl)=C1

0.898

View

Discussion: