Molecule Details

O=C(Cc1cccc(Cl)c1)Nc1cccnc1
3-aminopyridine-like Enamine Mcule MolPort Assayed
View on Fragalysis x10201
Molecular Properties
SMILES:
O=C(Cc1cccc(Cl)c1)Nc1cccnc1
MW: 246.06
Fraction sp3: 0.08
HBA: 2
HBD: 1
Rotatable Bonds: 3
TPSA: 41.99
cLogP: 2.92
Covalent Warhead:
Covalent Fragment:
Source
Enamine REAL: Z1079621790
Enamine Extended REAL: s_22____57778____3020518
Mcule: MCULE-6287436710
Mcule Ultimate: JXVSAHMJMLDNGG-UHFFFAOYSA-N
MolPort: MolPort-037-616-625
Activity Data
IC50 (µM) - Fluorescence: 53.717306778232
Trypsin IC50 (µM): 99.0
pIC50 (µM) - Fluorescence 4.26988576965696
Average Inhibition @ 20 µM - Fluorescence: 24.074975
Average Inhibition @ 50 µM - Fluorescence: 40.890465
Average Inhibition @ 50 µM - RapidFire: 52.3682892479862
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-05-26
O=C(Cc1cncc(Cl)c1)Nc1cccnc1

DAR-DIA-23aa0b97-16
0.661

View
O=C(Cc1cccc(Cl)c1)Nc1cncnc1

JAN-GHE-5a013bed-9
0.643

View
O=C(Cc1ccc(Cl)cc1)Nc1cccnc1

MAK-UNK-a7b37c5e-4
0.636

View
Cc1ccc(NC(=O)Cc2cccc(Cl)c2)cn1

EDG-MED-0da5ad92-13
0.627

View
N#Cc1cccc(CC(=O)Nc2cccnc2)c1

ANN-UNI-26382800-5
0.623

View
NS(=O)(=O)c1cccc(CC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-2
0.613

View
NS(=O)(=O)Cc1cccc(CC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-5
0.603

View
O=C(Cc1ccccc1)Nc1cccnc1

SAN-PRS-52b81272-2
0.600

View
CC(=O)NCCc1cccc(CC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-1
0.600

View
Cc1cncc(NC(=O)Cc2cccc(Cl)c2)c1

EDG-MED-0da5ad92-12
0.590

View
O=C(Cc1cccc(Cl)c1)Nc1cnccn1

JAN-GHE-5a013bed-8
0.567

View
O=C(Cc1cccc(Cl)c1)Nc1cn[nH]c1

MIC-UNK-66895286-1
0.567

View
O=C(Cc1cncnc1)Nc1cccnc1

SAD-SAT-24589cd1-4
0.561

View
O=C(CCl)Nc1cccnc1

MAK-UNK-ca11b4f7-1
0.558

View
O=C(Cc1cccc(N2CCCC2=O)c1)Nc1cccnc1

MAR-TRE-2fd8122f-39
0.557

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

ALP-POS-95b75b4d-8
0.548

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

SAM-UNK-2684b532-13
0.548

View
O=C(Cc1ccc(F)cc1)Nc1cccnc1

MAK-UNK-a7b37c5e-5
0.542

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1O

ALP-POS-95b75b4d-6
0.540

View
NC(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

ANN-UNI-98d2bf15-3
0.538

View
O=C(Cc1ccsc1)Nc1cccnc1

DAR-DIA-842b4336-10
0.533

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.531

View
O=C(Cc1ccccc1Cl)Nc1cccnc1

MAK-UNK-a7b37c5e-1
0.525

View
O=C(CC(=O)Nc1cccnc1)Nc1cccnc1

MAR-TRE-67513f76-81
0.519

View
O=C(Nc1cccnc1)Nc1cccc(Cl)c1

JOR-UNI-2fc98d0b-7
0.517

View
O=C(Nc1cccnc1)Nc1cccc(Cl)c1

JAN-GHE-83b26c96-19
0.517

View
O=C(Nc1cccnc1)Nc1cccc(Cl)c1

WAR-XCH-eb7b662f-7
0.517

View
O=C(Nc1cccnc1)Nc1cccc(Cl)c1

DAR-DIA-23aa0b97-14
0.517

View
O=C(Cc1ccc(Cl)s1)Nc1cccnc1

DAR-DIA-842b4336-13
0.516

View
Cn1cc(CC(=O)Nc2cccnc2)cn1

DAR-DIA-842b4336-11
0.516

View
O=C(Nc1cccnc1)c1cccc(Cl)c1

CHR-SOS-7098f804-12
0.508

View
O=C(Cc1cccc(Cl)c1)Nc1cnns1

JAN-GHE-5a013bed-6
0.508

View
O=C(Cc1cccc(Cl)c1)Nc1cncc(Cl)c1Cl

JAN-GHE-5a013bed-10
0.508

View
N#Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

MAK-UNK-6ca90168-23
0.507

View
N#Cc1cncc(CC(=O)Nc2cccnc2)c1

DAR-DIA-23aa0b97-17
0.500

View
Cn1cncc1NC(=O)Cc1cccc(Cl)c1

PET-UNK-8df914d1-4
0.500

View
O=C(Cc1cccc(Cl)c1)Nc1nncs1

NAU-LAT-e1818702-10
0.500

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)(F)F

SAM-UNK-2684b532-12
0.500

View
O=C(Cc1cccc(Cl)c1)Nc1nncs1

JAN-GHE-5a013bed-7
0.500

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)F

SAM-UNK-2684b532-11
0.500

View
NS(=O)(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

ALP-POS-95b75b4d-7
0.493

View
O=C(Cc1cccc(Cl)c1)Nc1cnc2ccccc2c1

ALP-POS-3b848b35-3
0.493

View
Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-14
0.492

View
O=C(Cc1cccc(Cl)c1)Nc1nnn[nH]1

JAN-GHE-5a013bed-11
0.492

View
CNCCC(C(=O)Nc1cccnc1)c1cccc(Cl)c1

ADA-UNI-f8e79267-11
0.486

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C1CC1

ALP-POS-95b75b4d-5
0.486

View
Cc1cncc(NC(=O)Cc2cccc(Cl)c2)c1C

PET-UNK-8df914d1-3
0.485

View
O=C(Cc1ccccc1C(=O)O)Nc1cccnc1

MAK-UNK-a7b37c5e-2
0.484

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1-c1ccccc1

ALP-POS-0c2c77e1-1
0.479

View
Cc1ncncc1NC(=O)Cc1cccc(Cl)c1

ABI-SAT-4d06482b-2
0.478

View
Cc1ccnc(C)c1NC(=O)Cc1cccc(Cl)c1

EDJ-MED-49816e9b-2
0.477

View
Cc1cnncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-16
0.477

View
O=C(C[S+]([O-])CC(=O)Nc1cccnc1)Nc1ccc(Cl)cc1

MAR-TRE-7f7bb9f0-74
0.477

View
Cc1[nH]ncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-21
0.477

View
C#Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

AGN-NEW-c7b24fe3-5
0.471

View
N#Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

AGN-NEW-c7b24fe3-4
0.471

View
Cc1c(N)cncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-3
0.471

View
Cc1cnn(C)c1NC(=O)Cc1cccc(Cl)c1

EDJ-MED-49816e9b-3
0.470

View
N#Cc1ccc(CC(=O)Nc2cccnc2)s1

DAR-DIA-842b4336-14
0.470

View
Cc1ccc(CC(=O)Nc2cccnc2)s1

DAR-DIA-842b4336-12
0.469

View
Cc1nnc(CC(=O)Nc2cccnc2)s1

ALE-HEI-f28a35b5-5
0.469

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2ncccc12

MIC-UNK-08cd9c58-1
0.466

View
C=Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

AGN-NEW-c7b24fe3-1
0.464

View
CCCN(C(=O)Cc1cccc(Cl)c1)c1cccnc1

JAN-GHE-83b26c96-16
0.464

View
Cc1ccnnc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-15
0.463

View
Cc1cnc(CC(=O)Nc2cccnc2)o1

DAR-DIA-842b4336-16
0.462

View
O=C(Cc1cccc(Cl)c1)Nc1cncn1C1CC1

PET-UNK-8df914d1-5
0.457

View
Cc1ccnc(N)c1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-18
0.456

View
CS(=O)(=O)NCCC(C(=O)Nc1cccnc1)c1cccc(Cl)c1

ADA-UNI-f8e79267-8
0.455

View
Cn1cnnc1NC(=O)Cc1cccc(Cl)c1

NAU-LAT-e1818702-7
0.455

View
Cc1nnc(NC(=O)Cc2cccc(Cl)c2)n1C

JAG-UCB-a3ef7265-15
0.455

View
Cn1cnnc1NC(=O)Cc1cccc(Cl)c1

JAG-UCB-a3ef7265-17
0.455

View
CNCCOC(C(=O)Nc1cccnc1)c1cccc(Cl)c1

ADA-UNI-f8e79267-10
0.453

View
O=C(Nc1cccnc1)Nc1cncc(Cl)c1

DAR-DIA-23aa0b97-15
0.452

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2ccccc12

ADA-UCB-6c2cb422-1
0.451

View
NC(=O)NC(=O)Cc1cccc(NC(=O)Nc2cccnc2)c1

WIL-UNI-5578df48-28
0.451

View
O=C(CCCBr)Nc1cccnc1

ALE-HEI-f28a35b5-14
0.450

View
O=C(CCS(=O)(=O)Cc1ccccc1)Nc1cccnc1

MAR-TRE-04c86cea-97
0.449

View
Cc1cc(N)ncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-17
0.449

View
Cc1nnn(C)c1NC(=O)Cc1cccc(Cl)c1

EDJ-MED-49816e9b-5
0.448

View
CC1(CC(=O)Nc2cccnc2)CCCCC1

MED-UNK-e6e8ef8a-6
0.446

View
CNCC1CC1(C(=O)Nc1cccnc1)c1cccc(Cl)c1

ADA-UNI-f8e79267-12
0.446

View
N=C(N)CCN(C(=O)Nc1cccnc1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-2
0.446

View
O=C(CC(c1ccccc1)c1ccccc1)Nc1cccnc1

AUS-ARG-7cfdce8f-11
0.444

View
Cc1cc(C)n2nc(CC(=O)Nc3cccnc3)nc2n1

MAR-TRE-9c797165-14
0.440

View
O=C(Nc1cccnc1)c1cc(Cl)ccc1O

CHR-SOS-7098f804-11
0.439

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1OCO2

EDJ-MED-a364e151-3
0.438

View
O=C(Nc1cccnc1)N(CCc1ccccc1)c1cccc(Cl)c1

ERI-UCB-ce40166b-23
0.436

View
O=C(Nc1cccnc1)Nc1cc(Cl)cc(Cl)c1

WAR-XCH-eb7b662f-3
0.435

View
O=C(Cc1cccc(Cl)c1)Nn1cnnc1

JAN-GHE-5a013bed-5
0.435

View
N#Cc1cnc(CC(=O)Nc2cccnc2)o1

DAR-DIA-842b4336-15
0.435

View
O=C(Cc1c[nH]c2ncccc12)Nc1cccnc1

KAL-WAB-eb347ebe-1
0.435

View
CCn1cc(C)c(C(=O)O)c1CC(=O)Nc1cccnc1

MAR-TRE-9c797165-94
0.431

View
Cn1cc(S(N)(=O)=O)cc1CC(=O)Nc1cccnc1

MAR-TRE-2fd8122f-37
0.431

View
NS(=O)(=O)c1cccc(CCC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-4
0.431

View
O=C(Cc1cccc(Cl)c1)Nc1cccc2[nH]ncc12

VLA-UCB-00f2c2b3-7
0.431

View
CS(=O)(=O)NCCOC(C(=O)Nc1cccnc1)c1cccc(Cl)c1

ADA-UNI-f8e79267-7
0.430

View
Cc1ccncc1N(C)C(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-1
0.429

View
Cc1ccncc1N(C)C(=O)Cc1cccc(Cl)c1

JAN-GHE-83b26c96-15
0.429

View
O=C(CC1(Cc2cccnc2)CCCCC1)Nc1cccnc1

CHR-SOS-59746812-6
0.429

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

1.000

View
O=C(CC1=CC(Cl)=CC=C1)NCC(=O)NC1=CC=CN=C1

0.729

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=C(C(=O)NC2=CC=CN=C2)C=C1

0.714

View
O=C(CC1=CC(Cl)=CC=C1)NCCC(=O)NC1=CC=CN=C1

0.705

View
O=C(CC1=CC(OCC2=CC(Cl)=CC=C2)=CC=C1)NC1=CC=CN=C1

0.697

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=C(C(=O)NC2=CC=CN=C2)C(Cl)=C1

0.692

View
O=C(COC(=O)CC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.683

View
O=C(CC1=CC(I)=CC=C1)NC1=CC=CN=C1

0.679

View
O=C(CCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.672

View
O=C(CC1=CC(Br)=CC=C1)NC1=CC=CN=C1

0.667

View
NC1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.667

View
O=C(CC1=CC(F)=CC=C1)NC1=CC=CN=C1

0.667

View
CC1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.667

View
O=C(CC1=CC=C(Cl)C(Cl)=C1)NC1=CC=CN=C1

0.649

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CN=CN=C1

0.643

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=C(OC2=CC=CN=C2)N=C1

0.642

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=C(OC2=CC=CN=C2)C=C1

0.641

View
O=C(CC1=CC=C(Cl)C=C1)NC1=CC=CN=C1

0.636

View
O=C(CC1=CC=CN=C1)NC1=CC=CN=C1

0.635

View
O=C(CC1=CC([N+](=O)[O-])=CC=C1)NC1=CC=CN=C1

0.633

View
O=C(CC1=CC(OCC2=CC=C(Cl)C=C2)=CC=C1)NC1=CC=CN=C1

0.627

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=NC=C1

0.625

View
O=C(COC1=CC=CC=C1NC(=O)CC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.625

View
O=C(CC1=CC(C(F)F)=CC=C1)NC1=CC=CN=C1

0.623

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=CN=C1

0.623

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=C(Cl)N=C1

0.621

View
O=C(CSCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.619

View
O=C(CC1=CC=C(CC(=O)NC2=CC=CN=C2)C=C1)NC1=CC=CN=C1

0.615

View
COC(=O)C1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.613

View
COCC1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.613

View
CS(=O)(=O)NC1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.613

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=CC(Cl)=C1

0.611

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=CC=C1

0.611

View
CC1=CC=C(CC(=O)NC2=CC=CN=C2)C=C1C

0.610

View
O=C(CC1=CC=C(F)C(F)=C1)NC1=CC=CN=C1

0.610

View
O=C(CCNCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.609

View
O=C(CCSCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.609

View
O=C(CC1=CC=C(Br)C(Cl)=C1)NC1=CC=CN=C1

0.607

View
O=C(CC1=CC=CC(C2CC2)=C1)NC1=CC=CN=C1

0.603

View
O=C(CC1=CC(OC(F)F)=CC=C1)NC1=CC=CN=C1

0.603

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CN=CC(Br)=C1

0.600

View
O=C(CC1=CC=CC(Cl)=C1)NC1=CC=C(F)N=C1

0.600

View
O=C(CN1CCN(C(=O)CC2=CC(Cl)=CC=C2)CC1)NC1=CC=CN=C1

0.597

View
O=C(CC1=CC=CN=C1)NC1=CC(Cl)=CC=C1

0.593

View
O=C(CCC1=CC(Cl)=CC=C1)NCC(=O)NC1=CC=CN=C1

0.591

View
CN(CC(=O)NC1=CC=CN=C1)CC1=CC=CC(Cl)=C1

0.591

View
CN(CCC(=O)NC1=CC=CN=C1)CC1=CC=CC(Cl)=C1

0.591

View
O=C(CC1=CC=CC(Cl)=C1)NC1=CC(F)=CN=C1

0.590

View
CC1=CN=CC(NC(=O)CC2=CC=CC(Cl)=C2)=C1

0.590

View
O=C(CCN1CCN(C(=O)CC2=CC(Cl)=CC=C2)CC1)NC1=CC=CN=C1

0.589

View
O=C(CC1=CC=CN=C1)NNC(=O)CC1=CC(Cl)=CC=C1

0.586

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=CC(OCC2=CC=CN=C2)=C1

0.586

View
O=C(CC1=CC(Cl)=CC=C1)NCC1=CC=C(C(=O)NC2=CC=CN=C2)C=C1

0.586

View
O=C(CNS(=O)(=O)CC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.582

View
O=C(CCNCCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.582

View
O=C(CC1=C(Cl)C=CC=C1Cl)NC1=CC=CN=C1

0.579

View
O=C(CC1=CC=C(Cl)N=C1)NC1=CC=CN=C1

0.576

View
O=C(CC1=CSC(CC2=CC(Cl)=CC=C2)=N1)NC1=CC=CN=C1

0.575

View
O=C(CNC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.574

View
O=C(CNC(=O)NCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.574

View
O=C(CCC1=CC(Cl)=CC=C1)NCCC(=O)NC1=CC=CN=C1

0.574

View
O=C(COC(=O)CCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.574

View
CCN(CC(=O)NC1=CC=CN=C1)CC1=CC=CC(Cl)=C1

0.574

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CN(CC2=CC=CN=C2)N=C1

0.571

View
O=C(NCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.571

View
O=C(CC1=CC=NC=C1)NC1=CC=CN=C1

0.571

View
O=C(CC1=CC(Cl)=CC=C1)N1CCN(C(=O)NC2=CC=CN=C2)CC1

0.571

View
O=C(CC1=CC=CC(OCC2=CC=CN=C2)=C1)NC1=CC=CN=C1

0.567

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CN=CC=N1

0.567

View
O=C(CN1CCN(CC2=CC(Cl)=CC=C2)CC1)NC1=CC=CN=C1

0.565

View
O=C(CCNS(=O)(=O)CC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.565

View
O=C(CC1=CC(Cl)=CC=C1Cl)NC1=CC=CN=C1

0.565

View
O=C(CC1=CN=CN=C1)NC1=CC=CN=C1

0.561

View
O=C(CC1=CC(Cl)=CC=C1)NCC1=CC=CN=C1

0.557

View
O=C(CNS(=O)(=O)CCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.557

View
O=C(CNC(=O)NCCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.557

View
O=C(CCNCCCC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.557

View
O=C(CC1=CC=C(Cl)C=C1Br)NC1=CC=CN=C1

0.556

View
O=C(NCC1=CC(Cl)=CC=C1)C(=O)NC1=CC=CN=C1

0.554

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=CC(Br)=C1

0.550

View
NCCN(CC(=O)NC1=CC=CN=C1)CC1=CC=CC(Cl)=C1

0.549

View
O=C(CC1=CC=C2C=CC=CC2=C1)NC1=CC=CN=C1

0.547

View
O=C(CCN1CCN(CC2=CC(Cl)=CC=C2)CC1)NC1=CC=CN=C1

0.542

View
O=C(CSC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.538

View
O=C(CC1=CC(OCC2=CC(Cl)=CC=C2)=CC=C1)NCC(=O)NC1=CC=CN=C1

0.538

View
NCCN(CCC(=O)NC1=CC=CN=C1)CC1=CC=CC(Cl)=C1

0.534

View
O=C(NC1=CC=CN=C1)NC1=CC(Cl)=CC=C1

0.517

View
O=C(CC1=CC=CC(OCC2=CC=CN=C2)=C1)NC1=CC(Cl)=CC=C1

0.514

View
O=C(CC1=CC=CN=C1)NC1=CC=CC(NC(=O)CC2=CC=CN=C2)=C1

0.500

View
O=C(CC1=CC=CN=C1)NC1=CC=C(Cl)C=C1

0.500

View
O=C(CC1=CC(Cl)=CC=C1)NCC1=CC=CC(NC(=O)C2=CC=CN=C2)=C1

0.493

View
O=C(CC1=CC=CN=C1)NC1=CC(Cl)=CC(Cl)=C1

0.492

View
O=C(CC1=CC=CN=C1)NC1=CC=C(C(=O)NC2=CC=CN=C2)C(Cl)=C1

0.486

View
O=C(CCC1=CC=CN=C1)NC1=CC(Cl)=CC=C1

0.485

View
O=C(CC1=CC=CN=C1)NC1=CC=C(OC2=CC(Cl)=CC=C2)C=C1

0.479

View
O=C(CC1=CC=NC=C1)NC1=CC(Cl)=CC=C1

0.468

View
O=C(CC1=CC=C(Cl)C=C1)NC1=CC=C(C(=O)NC2=CC=CN=C2)C(Cl)=C1

0.466

View
O=C(CC1=CC=CN=C1)NNC1=CC(Cl)=CC=C1

0.463

View
O=C(CC1=CC=CN=C1)NNC(=O)NC1=CC(Cl)=CC=C1

0.457

View
O=C(CC1=CC=CN=C1)NC1=CC(O)=CC=C1

0.453

View
Cc1cccc(CC(=O)Nc2cccnc2)c1

0.667

View
Clc1ccc(CC(=O)Nc2cccnc2)cc1Cl

0.649

View
Clc1ccc(CC(=O)Nc2cccnc2)cc1

0.636

View
O=C(Cc1ccccc1)Nc1cccnc1

0.600

View
Clc1cccc(Cl)c1CC(=O)Nc1cccnc1

0.579

View
Clc1ccc(CC(=O)Nc2cccnc2)c(Cl)c1

0.574

View
Cc1ccc(CC(=O)Nc2cccnc2)cc1

0.542

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

0.531

View
Clc1ccccc1CC(=O)Nc1cccnc1

0.525

View
Cc1ccccc1CC(=O)Nc1cccnc1

0.476

View
CC(C(=O)Nc1cccnc1)c1ccc(Cl)cc1

0.388

View
CC(C(=O)Nc1cccnc1)c1ccccc1

0.338

View
Oc1ccncc1NC(=O)Cc1ccc(Cl)cc1

0.310

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)cc1

0.306

View
CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

0.295

View
CN(C(=O)Cc1cc(Cl)ccc1Br)c1cccnc1

0.286

View
C(NC1=CC=CN=C1)(=O)CC1=CC=CC(Cl)=C1

1.000

View
C(NC1=CC=CN=C1)(=O)CC1=CC=C(Cl)C=C1

0.940

View
C(NC1=CN=C(Cl)C=C1)(=O)CC1=CC=CC(Cl)=C1

0.929

View
C(NC1=CC=CN=C1)(=O)CC1=C(Cl)C=CC=C1

0.908

View
C(NC1=CN=C(F)C=C1)(=O)CC1=CC=CC(Cl)=C1

0.908

View

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