Molecule Details

N#Cc1cccc(CC(=O)Nc2cccnc2)c1
3-aminopyridine-like Enamine MolPort Assayed
View on Fragalysis x2600
Molecular Properties
SMILES:
N#Cc1cccc(CC(=O)Nc2cccnc2)c1
MW: 237.262
Fraction sp3: 0.07
HBA: 3
HBD: 1
Rotatable Bonds: 3
TPSA: 65.78
cLogP: 2.13448
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine SCR: Z1343543528
Enamine REAL: Z1343543528
Enamine Extended REAL: s_22____57778____6586228
MolPort: MolPort-047-318-294
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 11.40413
Average Inhibition @ 50 µM - Fluorescence: 24.96099
Average Inhibition @ 50 µM - RapidFire: 11.54
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-03-31
Synthesis Location: enamine
Shipped: 2020-04-17
N#Cc1cncc(CC(=O)Nc2cccnc2)c1

DAR-DIA-23aa0b97-17
0.625

View
O=C(Cc1cccc(Cl)c1)Nc1cccnc1

EDG-MED-0da5ad92-2
0.623

View
N#Cc1cccc(NC(=O)Cc2cccnc2)c1

DAR-DIA-23aa0b97-4
0.585

View
N#Cc1cccc(CC(=O)Nc2cnccc2C#N)c1

SAD-SAT-24589cd1-5
0.574

View
N#Cc1cccc(CC(=O)Nc2cnccc2CN)c1

SAD-SAT-24589cd1-8
0.571

View
NS(=O)(=O)c1cccc(CC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-2
0.567

View
Cc1ccncc1NC(=O)Cc1cccc(C#N)c1

TRY-UNI-714a760b-20
0.565

View
NS(=O)(=O)Cc1cccc(CC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-5
0.559

View
N#Cc1cccc(CC(=O)Nc2cnccc2[N+](=O)[O-])c1

SAD-SAT-24589cd1-1
0.556

View
CS(=O)(=O)c1ccncc1NC(=O)Cc1cccc(C#N)c1

SAD-SAT-24589cd1-3
0.556

View
O=C(Cc1ccccc1)Nc1cccnc1

SAN-PRS-52b81272-2
0.550

View
CC(=O)NCCc1cccc(CC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-1
0.535

View
O=C(Cc1cncnc1)Nc1cccnc1

SAD-SAT-24589cd1-4
0.516

View
N#Cc1cccc(NC(=O)Nc2cccnc2)c1

DAR-DIA-23aa0b97-5
0.515

View
N#Cc1cccc(NC(=O)Nc2cccnc2)c1

ANN-UNI-26382800-4
0.515

View
N#Cc1cccc(NC(=O)Nc2cccnc2)c1

WAR-XCH-eb7b662f-1
0.515

View
N#Cc1cccc(NC(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-2
0.515

View
O=C(Cc1ccc(Cl)cc1)Nc1cccnc1

MAK-UNK-a7b37c5e-4
0.508

View
O=C(Cc1cncc(Cl)c1)Nc1cccnc1

DAR-DIA-23aa0b97-16
0.508

View
Cc1c(N)cncc1NC(=O)Cc1cccc(C#N)c1

TRY-UNI-714a760b-19
0.507

View
O=C(CC(=O)Nc1cccnc1)Nc1cccnc1

MAR-TRE-67513f76-81
0.500

View
O=C(Cc1cccc(N2CCCC2=O)c1)Nc1cccnc1

MAR-TRE-2fd8122f-39
0.500

View
O=C(Cc1ccc(F)cc1)Nc1cccnc1

MAK-UNK-a7b37c5e-5
0.500

View
N#Cc1ccc(CC(=O)Nc2cccnc2)s1

DAR-DIA-842b4336-14
0.500

View
N#Cc1cncc(NC(=O)Cc2cccnc2)c1

DAR-DIA-23aa0b97-6
0.493

View
O=C(Cc1ccsc1)Nc1cccnc1

DAR-DIA-842b4336-10
0.492

View
N#Cc1cnc(CC(=O)Nc2cccnc2)o1

DAR-DIA-842b4336-15
0.486

View
N#Cc1cccc(CC(=O)Nc2cnccc2CN2CCNCC2)c1

MAK-UNK-748f8b7a-6
0.482

View
N#Cc1cccc(CC(=O)Nc2cnccc2CN2CCOCC2)c1

SAD-SAT-24589cd1-6
0.482

View
Cn1cc(CC(=O)Nc2cccnc2)cn1

DAR-DIA-842b4336-11
0.478

View
C#Cc1cccc(NC(=O)CC(=O)Nc2cccnc2)c1

MAR-TRE-2fd8122f-57
0.471

View
O=C(Cc1ccccc1C(=O)O)Nc1cccnc1

MAK-UNK-a7b37c5e-2
0.471

View
N#Cc1cccc(N(CCC(=N)N)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-7
0.468

View
N#Cc1cccc(CC(=O)Nc2cnccc2C2CCCNC2)c1

SAD-SAT-24589cd1-10
0.459

View
O=C(CCl)Nc1cccnc1

MAK-UNK-ca11b4f7-1
0.458

View
Cc1nnc(CC(=O)Nc2cccnc2)s1

ALE-HEI-f28a35b5-5
0.456

View
N#Cc1ccc(NC(=O)Nc2cccnc2)cc1

ANN-UNI-26382800-3
0.455

View
N#Cc1ccc(NC(=O)Nc2cccnc2)cc1

JOH-UNK-14e6adc5-2
0.455

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CC(=O)N1CCC(c2ccncc2NC(=O)Cc2cccc(C#N)c2)CC1

SAD-SAT-24589cd1-9
0.453

View
N#Cc1ccc(O)c(NC(=O)Cc2cccnc2)c1

BEN-DND-61647d40-8
0.451

View
N#Cc1cccc(N(CCC2CC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-9
0.450

View
N#Cc1cccc(N(CN2CCOCC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-3
0.442

View
O=C(Cc1ccccc1Cl)Nc1cccnc1

MAK-UNK-a7b37c5e-1
0.441

View
N#Cc1cccc(N(CC2CCCCC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-20
0.440

View
O=C(CCS(=O)(=O)Cc1ccccc1)Nc1cccnc1

MAR-TRE-04c86cea-97
0.438

View
N#Cc1cccc(N(CCC2CCCCC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-18
0.435

View
O=C(Cc1ccc(Cl)s1)Nc1cccnc1

DAR-DIA-842b4336-13
0.435

View
N#Cc1cncc(NC(=O)Nc2cccnc2)c1

CHR-SOS-363cfb78-1
0.435

View
Cc1ccc(CC(=O)Nc2cccnc2)s1

DAR-DIA-842b4336-12
0.435

View
N#Cc1ccc(NCc2cccc(NC(=O)Nc3cccnc3)c2)nc1

MAK-UNK-30aad1f1-6
0.429

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Cc1cnc(CC(=O)Nc2cccnc2)o1

DAR-DIA-842b4336-16
0.429

View
N#Cc1ccc(CNC(=O)N2CCOCC2)c(CC(=O)Nc2cccnc2)c1

SAD-SAT-f25ee457-3
0.427

View
N#Cc1cccc(NC(=O)Cc2cncc(N)c2)c1

DAR-DIA-23aa0b97-3
0.427

View
CN1CCN(CN(C(=O)Nc2cccnc2)c2cccc(C#N)c2)CC1

JOR-UNI-61e7b1d5-14
0.425

View
N#Cc1cccc(CNC(=O)Cc2c[nH]c3ncccc23)c1

TRY-UNI-1fd04853-6
0.425

View
CC1COC(CO)CN1Cc1ccncc1NC(=O)Cc1cccc(C#N)c1

MAK-UNK-748f8b7a-9
0.421

View
Cn1cc(S(N)(=O)=O)cc1CC(=O)Nc1cccnc1

MAR-TRE-2fd8122f-37
0.421

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NC(=O)NC(=O)Cc1cccc(NC(=O)Nc2cccnc2)c1

WIL-UNI-5578df48-28
0.421

View
N#Cc1ccc(CC(C#N)C(=O)Nc2cccnc2)cc1

MAR-TRE-2fd8122f-69
0.419

View
O=C(CC1(Cc2cccnc2)CCCCC1)Nc1cccnc1

CHR-SOS-59746812-6
0.419

View
N#Cc1cccc(N(CCN2CCOCC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-16
0.416

View
O=C(CCCBr)Nc1cccnc1

ALE-HEI-f28a35b5-14
0.415

View
N#Cc1cccc(N(CN2CCNCC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-12
0.414

View
O=C(CC(c1ccccc1)c1ccccc1)Nc1cccnc1

AUS-ARG-7cfdce8f-11
0.412

View
N#Cc1cc(Cl)cc(NC(=O)Nc2cccnc2)c1

WAR-XCH-eb7b662f-2
0.411

View
N#Cc1ccc(Nc2ccc(NC(=O)Nc3cccnc3)cc2)nc1

MAK-UNK-30aad1f1-12
0.410

View
N#Cc1cccc(N(CN2CCC(O)CC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-5
0.409

View
CN1CCN(CCN(C(=O)Nc2cccnc2)c2cccc(C#N)c2)CC1

JOR-UNI-61e7b1d5-28
0.409

View
N#Cc1cccc(N(CCN2CCCCC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-30
0.409

View
O=C(CC1(Cc2ccccc2)CCCCC1)Nc1cccnc1

CHR-SOS-59746812-5
0.408

View
N#Cc1ccc(Nc2cccc(NC(=O)Nc3cccnc3)c2)nc1

MAK-UNK-30aad1f1-8
0.407

View
O=C(Cc1c[nH]c2ncccc12)Nc1cccnc1

KAL-WAB-eb347ebe-1
0.405

View
O=C(CC1(Cc2cccnc2)CCCC1)Nc1cccnc1

CHR-SOS-59746812-2
0.405

View
O=C(CC1(C#Cc2cccnc2)CCCCC1)Nc1cccnc1

CHR-SOS-b301fc01-2
0.405

View
Cc1nc2c(C#N)cnn2c(O)c1CC(=O)Nc1cccnc1

MAR-TRE-2fd8122f-46
0.405

View
N#Cc1cccc(N(CCN2CCNCC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-26
0.404

View
O=C(CC1(c2cccnc2)CCCC1)Nc1cccnc1

CHR-SOS-f7373dd1-5
0.403

View
Cc1ccc(NC(=O)Cc2cccc(Cl)c2)cn1

EDG-MED-0da5ad92-13
0.403

View
NS(=O)(=O)c1cccc(CCC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-4
0.403

View
N#Cc1cccc(N(CCN2CCC(O)CC2)C(=O)Nc2cccnc2)c1

JOR-UNI-61e7b1d5-24
0.400

View
CC1CCN(CN(C(=O)Nc2cccnc2)c2cccc(C#N)c2)CC1

JOR-UNI-61e7b1d5-22
0.400

View
O=C(CC1CCCCC1)Nc1cccnc1

ALE-HEI-f28a35b5-9
0.400

View
O=C(CC1CCCCC1)Nc1cccnc1

FRA-FAC-9ed5a63a-1
0.400

View
O=C(CC1CCCCC1)Nc1cccnc1

AAR-POS-d2a4d1df-13
0.400

View
N#Cc1ccc(NCc2ccc(NC(=O)Nc3cccnc3)cc2)nc1

MAK-UNK-30aad1f1-7
0.398

View
N#Cc1cccc(NC(=O)Cc2cncc3ncccc23)c1

DAR-DIA-23aa0b97-18
0.398

View
Cc1cc(C)n2nc(CC(=O)Nc3cccnc3)nc2n1

MAR-TRE-9c797165-14
0.395

View
N#Cc1cnc(O)c(NC(=O)Cc2cccnc2)c1

BEN-DND-61647d40-7
0.395

View
O=C(CC1(Cc2ccccc2)CCCC1)Nc1cccnc1

CHR-SOS-59746812-1
0.395

View
CC1(CC(=O)Nc2cccnc2)CCCCC1

MED-UNK-e6e8ef8a-6
0.394

View
O=C(C[C@H]1CCCC[C@H]1O)Nc1cccnc1

MED-UNK-e6e8ef8a-5
0.394

View
COc1ccc(CC(=O)Nc2cccnc2)cc1S(=O)(=O)N1CCOCC1

MAR-TRE-2fd8122f-35
0.393

View
Cc1c(CC(=O)Nc2cccnc2)c(=O)oc2cc(O)ccc12

MAR-TRE-04c86cea-41
0.393

View
O=C(C[C@H](NCc1cccnc1)C(=O)O)Nc1cccnc1

MAR-TRE-d0525fbf-91
0.392

View
O=C(CC1(c2cccnc2)CCCCC1)Nc1cccnc1

CHR-SOS-f7373dd1-2
0.392

View
CCc1ccc2oc(Br)c(CC(=O)Nc3cccnc3)c2c1

MAR-TRE-f6f5f473-95
0.390

View
O=C(CC1(C#Cc2ccnnc2)CCCCC1)Nc1cccnc1

CHR-SOS-b301fc01-5
0.390

View
N#Cc1cccc(NC(=O)Cc2c[nH]c3ncccc23)c1

DAR-DIA-23aa0b97-1
0.390

View
NCCc1nc(CC(=O)Nc2cccnc2)cs1

MAR-TRE-2fd8122f-99
0.390

View
Cc1cn(C)c(CC(=O)Nc2cccnc2)c1C(=O)O

MAR-TRE-67513f76-13
0.390

View
N#CC1=CC=C(CC(=O)NC2=CC=CN=C2)C=C1

0.623

View
O=C(CC1=CC(Cl)=CC=C1)NC1=CC=CN=C1

0.623

View
O=C(CC1=CC(I)=CC=C1)NC1=CC=CN=C1

0.623

View
NC1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.613

View
O=C(CC1=CC(Br)=CC=C1)NC1=CC=CN=C1

0.613

View
O=C(CC1=CC(F)=CC=C1)NC1=CC=CN=C1

0.613

View
CC1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.613

View
N#CC1=CC(CS(=O)(=O)NCC(=O)NC2=CC=CN=C2)=CC=C1

0.606

View
CN(CC(=O)NC1=CC=CN=C1)CC1=CC=CC(C#N)=C1

0.606

View
CN(CCC(=O)NC1=CC=CN=C1)CC1=CC=CC(C#N)=C1

0.606

View
N#CC1=CC(CNC(=O)NCC(=O)NC2=CC=CN=C2)=CC=C1

0.597

View
N#CC1=CC(CNC(=O)NC2=CC=CN=C2)=CC=C1

0.597

View
N#CCOC1=CC(CC(=O)NC2=CC=CN=C2)=CC=C1

0.594

View
N#CC1=CC(NC(=O)CC2=CC=CN=C2)=CC=C1

0.585

View
O=C(CC1=CC([N+](=O)[O-])=CC=C1)NC1=CC=CN=C1

0.585

View
N#CC1=CC(CS(=O)(=O)NCCC(=O)NC2=CC=CN=C2)=CC=C1

0.581

View
CN(CCC(=O)NC1=CC=CN=C1)CCC1=CC=CC(C#N)=C1

0.581

View
N#CC1=CC(CNC(=O)C(=O)NC2=CC=CN=C2)=CC=C1

0.580

View
O=C(CC1=CC=CN=C1)NC1=CC=CN=C1

0.579

View
O=C(CC1=CC(C(F)F)=CC=C1)NC1=CC=CN=C1

0.576

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=CN=C1

0.576

View
C=CCN(CC(=O)NC1=CC=CN=C1)CC1=CC=CC(C#N)=C1

0.573

View
COCC1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.567

View
CS(=O)(=O)NC1=CC=CC(CC(=O)NC2=CC=CN=C2)=C1

0.567

View
N#CC1=CC(CCNC(=O)NCC(=O)NC2=CC=CN=C2)=CC=C1

0.566

View
N#CC1=CC(CCNC(=O)NC2=CC=CN=C2)=CC=C1

0.563

View
CN(CC1=CC=CC(C#N)=C1)C(=O)NC1=CC=CN=C1

0.563

View
O=C(CC1=CC=C(CC(=O)NC2=CC=CN=C2)C=C1)NC1=CC=CN=C1

0.561

View
N#CC1=CC(OCC(=O)NC2=CC=CN=C2)=CC=C1

0.559

View
O=C(CC1=CC=CC(C2CC2)=C1)NC1=CC=CN=C1

0.559

View
C=CCN(CCC(=O)NC1=CC=CN=C1)CC1=CC=CC(C#N)=C1

0.558

View
N#CC1=CC(C(=O)NCC(=O)NC2=CC=CN=C2)=CC=C1

0.557

View
CCCCN(CC(=O)NC1=CC=CN=C1)CC1=CC=CC(C#N)=C1

0.551

View
N#CC1=CC(CCNC(=O)C(=O)NC2=CC=CN=C2)=CC=C1

0.548

View
CN(CC1=CC=CC(C#N)=C1)C(=O)C(=O)NC1=CC=CN=C1

0.541

View
N#CC1=CC(SCC(=O)NC2=CC=CN=C2)=CC=C1

0.535

View
C=CCN(CC1=CC=CC(C#N)=C1)C(=O)NC1=CC=CN=C1

0.533

View
N#CC1=CC(COC2=CC=C(NC(=O)NC3=CC=CN=C3)C=C2)=CC=C1

0.532

View
N#CC1=CC=CC(CNC2=CC=CN=C2)=C1

0.531

View
CCCCN(CCC(=O)NC1=CC=CN=C1)CC1=CC=CC(C#N)=C1

0.531

View
N#CC1=CC(C(=O)NC2=CC=CN=C2)=CC=C1

0.530

View
N#CC1=CC(CNC(=O)CC2=CC=CN=C2)=CC=C1

0.529

View
N#CC1=CC(C(=O)OCC(=O)NC2=CC=CN=C2)=CC=C1

0.528

View
N#CC1=CC(S(=O)(=O)NCC(=O)NC2=CC=CN=C2)=CC=C1

0.527

View
N#CC1=CC(CNC2=CC=C(C(=O)NC3=CC=CN=C3)C=C2)=CC=C1

0.526

View
O=C(CC1=CC=NC=C1)NC1=CC=CN=C1

0.525

View
N#CC1=CC(NC(=O)NCC(=O)NC2=CC=CN=C2)=CC=C1

0.521

View
N#CC1=CC(C(=O)NCCC(=O)NC2=CC=CN=C2)=CC=C1

0.520

View
N#CC1=CC(COC2=CC=C(NC(=O)CC3=CC=CN=C3)C=C2)=CC=C1

0.519

View
CCCCN(CC1=CC=CC(C#N)=C1)C(=O)NC1=CC=CN=C1

0.519

View
CN(C)CCN(CC1=CC=CC(C#N)=C1)C(=O)NC1=CC=CN=C1

0.519

View
N#CC1=CC(COC2=CC(NC(=O)CC3=CC=CN=C3)=CC=C2)=CC=C1

0.519

View
N#CC1=CC(CNC2=CC=CC=C2OCC(=O)NC2=CC=CN=C2)=CC=C1

0.518

View
N#CC1=CC(NC(=O)NC2=CC=CN=C2)=CC=C1

0.515

View
N#CC1=CC(SCCC(=O)NC2=CC=CN=C2)=CC=C1

0.514

View
N#CC1=CC(NC(=O)C(=O)NCC(=O)NC2=CC=CN=C2)=CC=C1

0.514

View
N#CC1=CC(S(=O)(=O)NCCC(=O)NC2=CC=CN=C2)=CC=C1

0.513

View
C=CCN(CC1=CC=CC(C#N)=C1)C(=O)C(=O)NC1=CC=CN=C1

0.513

View
N#CC1=CC(COC2=CC=C(NC(=O)C(=O)NC3=CC=CN=C3)C=C2)=CC=C1

0.513

View
N#CC1=CC(NC(=O)CC2=CC=CC(OCC3=CC=CN=C3)=C2)=CC=C1

0.512

View
N#CC1=CC(COC2=CC(NC(=O)C(=O)NC3=CC=CN=C3)=CC=C2)=CC=C1

0.506

View
N#CC1=CC(CN2CCC(C(=O)NC3=CC=CN=C3)CC2)=CC=C1

0.506

View
N#CC1=CC(COC2=CC(NC(=O)NC3=CC=CN=C3)=CC=C2)=CC=C1

0.500

View
N#CC1=CC=C(CCC(=O)NC2=CC=CN=C2)C=C1

0.500

View
CC(NCC(=O)NC1=CC=CN=C1)C1=CC=CC(C#N)=C1

0.500

View
NC1=CC=C(CC(=O)NC2=CC=CN=C2)C=C1

0.500

View
N#CC1=CC(CN2CCC(NCCC(=O)NC3=CC=CN=C3)CC2)=CC=C1

0.500

View
N#CC1=CC(OC2=CC=C(NC(=O)CC3=CC=CN=C3)C=N2)=CC=C1

0.487

View
N#CC1=CC(NC(=O)CCC2=CC=CN=C2)=CC=C1

0.486

View
N#CC1=CC=C(CC(=O)NCC(=O)NC2=CC=CN=C2)C=C1

0.486

View
N#CC1=CC(NC(=O)CC2=CC(I)=CC=C2)=CC=C1

0.485

View
N#CC1=CC=C(NC(=O)CC2=CC=CN=C2)C=C1

0.485

View
N#CC1=CC(NC(=O)C2=CC(NC(=O)CC3=CC=CN=C3)=CC=C2)=CC=C1

0.481

View
N#CC1=CC(OC2=CC=C(NC(=O)CC3=CC=CN=C3)C=C2)=CC=C1

0.481

View
N#CC1=CC(CCNC(=O)CC2=CC=CN=C2)=CC=C1

0.479

View
N#CC1=CC(NNC(=O)NC2=CC=CN=C2)=CC=C1

0.479

View
N#CC1=CC(NC(=O)CC2=CC(Cl)=CC=C2)=CC=C1

0.478

View
N#CC1=CC(NC(=O)C(=O)NNC(=O)CC2=CC=CN=C2)=CC=C1

0.474

View
N#CC1=CC(CS(=O)(=O)NC(=O)CC2=CC=CN=C2)=CC=C1

0.473

View
N#CC1=CC(NC(=O)CC2=CC(Br)=CC=C2)=CC=C1

0.471

View
N#CC1=CC(NC(=O)CC2=CC=NC=C2)=CC=C1

0.471

View
N#CC1=CC=C(CC(=O)NC2=CC=C(C(=O)NC3=CC=CN=C3)C=C2)C=C1

0.468

View
N#CC1=CC=C(CC(=O)NCCC(=O)NC2=CC=CN=C2)C=C1

0.467

View
N#CC1=CC(NNC(=O)CC2=CC=CN=C2)=CC=C1

0.466

View
N#CC1=CC=C(NC(=O)CC2=CC=CN=C2)C=N1

0.464

View
N#CC1=CC(NC(=O)NNC(=O)CC2=CC=CN=C2)=CC=C1

0.461

View
N#CC1=CC(NC(=O)CSCC2=CC=CN=C2)=CC=C1

0.461

View
N#CC1=CC(NC(=O)COCC2=CC=CN=C2)=CC=C1

0.461

View
O=C(CC1=CC=CN=C1)NC1=CC=CC(NC(=O)CC2=CC=CN=C2)=C1

0.460

View
N#CC1=CC(NC(=O)CC2=CN=CN=C2)=CC=C1

0.457

View
N#CC1=CC(NC(=O)CCNCC2=CC=CN=C2)=CC=C1

0.455

View
C#CC1=CC(NC(=O)CC2=CC=CN=C2)=CC=C1

0.451

View
N#CC1=CC=C(NC(=O)CC2=CC=CN=C2)C=C1C#N

0.451

View
N#CC1=CC(NC(=O)CC2=CC=C(CC(=O)NC3=CC=CC(C#N)=C3)C=C2)=CC=C1

0.446

View
N#CC1=CC(NC(=O)CCSCC2=CC=CN=C2)=CC=C1

0.443

View
N#CC1=CC=C(S(=O)(=O)NCC(=O)NC2=CC=CN=C2)C(F)=C1

0.443

View
N#CC1=CC=C(OC2=CC(NC(=O)CC3=CC=CN=C3)=CC=C2)C=C1

0.443

View
CN(CC(=O)NC1=CC=CC(C#N)=C1)CC1=CC=CN=C1

0.443

View
N#CC1=CC(NC(=O)COCC(=O)NCC2=CC=CN=C2)=CC=C1

0.427

View
O=C(CC1=CC=CN=C1)NC1=CC=CC(C#CC2=CC=CC=C2)=C1

0.410

View
O=C(Cc1cccc(c1)C#N)Nc1cccnc1

1.000

View
O=C(Cc1ccc(cc1)C#N)Nc1cccnc1

0.623

View
Cc1cccc(CC(=O)Nc2cccnc2)c1

0.613

View
Cc1ccncc1NC(=O)Cc1cccc(c1)C#N

0.565

View
O=C(Cc1ccccc1)Nc1cccnc1

0.550

View
Cc1ccc(CC(=O)Nc2cccnc2)cc1C

0.538

View
Clc1ccc(CC(=O)Nc2cccnc2)cc1

0.508

View
Cc1ccc(CC(=O)Nc2cccnc2)cc1

0.500

View
Fc1ccc(CC(=O)Nc2cccnc2)cc1

0.500

View
CCCCc1ccc(CC(=O)Nc2cccnc2)cc1

0.457

View
Cc1ccccc1CC(=O)Nc1cccnc1

0.441

View
Cc1ccc(C)c(CC(=O)Nc2cccnc2)c1

0.437

View
CC(C(=O)Nc1cccnc1)c1ccccc1

0.315

View
CC(C(=O)Nc1cnccc1C)c1cccc(c1)C#N

0.294

View
Cc1ccncc1NC(=O)Cc1ccccc1

0.260

View
CN(C(=O)Cc1cc(C)ccc1C)c1cccnc1

0.217

View
C(NC1=CC=CN=C1)(=O)CC1=CC=C(C#N)C=C1

0.623

View
C(NC1=CC=CN=C1)(=O)CC1C=CC=C(C)C=1

0.613

View
C(NC1=CC=CN=C1)(=O)CC1=CC=CC=C1

0.550

View
C(NC1=CC=CN=C1)(=O)CC1C=CC(F)=C(C)C=1

0.515

View
C(NC1=CC=CN=C1)(=O)CC1=CC=C(C)C=C1

0.500

View
C(NC1=CC=CN=C1)(=O)CC1=CC=C(CC)C=C1

0.500

View
C(NC1=CC=CN=C1)(=O)CC1=CC=C(C)C=C1C

0.443

View
C(NC1=CC=CN=C1)(=O)CC1C(C)=CC=C(C)C=1

0.437

View
C(NC1=CN=C(C#N)C=C1)(=O)CC1C=CC=C(C)C=1

0.419

View
C(NC1=CN=C(C#C)C=C1)(=O)CC1C=CC=C(C)C=1

0.382

View
C(NC1=CN=C(Br)C=C1)(=O)CC1C=CC=C(C)C=1

0.365

View
C(NC1=CN=C(Cl)C=C1)(=O)CC1C=CC=C(C)C=1

0.360

View
C(NC1=CN=C(F)C=C1)(=O)CC1C=CC=C(C)C=1

0.360

View
C(NC1=CN=C(Cl)C=C1)(=O)CC1=CC=C(C#N)C=C1

0.351

View
C(NC1=CN=C(F)C=C1)(=O)CC1=CC=C(C#N)C=C1

0.351

View
C(NC1=C(C)C=CN=C1)(=O)CC1C=CC=C(C)C=1

0.325

View
C(NC1=C(Cl)C=CN=C1)(=O)CC1C=CC=C(C)C=1

0.316

View
C(NC1=C(Br)N=CC=C1)(=O)CC1C=CC=C(C)C=1

0.287

View
C(NC1=C(F)N=CC=C1)(=O)CC1C=CC=C(C)C=1

0.287

View
C(NC1=C(Cl)N=CC=C1)(=O)CC1C=CC=C(C)C=1

0.287

View


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