All of the substances displayed on this site are designed to be biologically active. The prediction of toxic effects remains an extremely difficult problem. Therefore all materials described here should be treated as having high biological activity with a risk of severe toxicity which may include, but is not limited to: cardiac impairment up to and including the risk of causing cardiac arrest, irreversible liver or renal damage, carcinogenicity, mutagenicity, teratogenicity (risk to the unborn child) and, or generation of a severe allergic response. Unless otherwise stated, no material has been profiled for toxicological effects and therefore no materials should under any circumstances be synthesised and taken for any therapeutic or recreational effect by any person or for any other purpose.