Molecule Details

EDJ-MED-49816e9b-2 View Submission
Cc1ccnc(C)c1NC(=O)Cc1cccc(Cl)c1
3-aminopyridine-like Enamine Assayed
View on Fragalysis x10334
Molecular Properties
SMILES:
Cc1ccnc(C)c1NC(=O)Cc1cccc(Cl)c1
MW: 274.09
Fraction sp3: 0.2
HBA: 2
HBD: 1
Rotatable Bonds: 3
TPSA: 41.99
cLogP: 3.53
Covalent Warhead: ✗
Covalent Fragment: ✗
Source
Enamine REAL: Z2194192724
Enamine Extended REAL: s_11____10117600____3020516
Activity Data
Average Inhibition @ 20 µM - Fluorescence: -1.5983266
Average Inhibition @ 50 µM - Fluorescence: 13.252905
Average Inhibition @ 50 µM - RapidFire: 8.4970087445
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-06-10
Cc1ccnc(N)c1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-18
0.741

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Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-14
0.597

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Cc1ccnnc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-15
0.562

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Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.538

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Cc1ccc(NC(=O)Cc2cccc(Cl)c2)cn1

EDG-MED-0da5ad92-13
0.531

View
Cc1cnn(C)c1NC(=O)Cc1cccc(Cl)c1

EDJ-MED-49816e9b-3
0.523

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Cc1[nH]ncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-21
0.508

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Cc1cnncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-16
0.508

View
Cc1ncncc1NC(=O)Cc1cccc(Cl)c1

ABI-SAT-4d06482b-2
0.507

View
Cc1nnn(C)c1NC(=O)Cc1cccc(Cl)c1

EDJ-MED-49816e9b-5
0.500

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Cc1cc(N)ncc1NC(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-17
0.500

View
O=C(Cc1cccc(Cl)c1)Nc1cnccn1

JAN-GHE-5a013bed-8
0.500

View
Cc1cncc(NC(=O)Cc2cccc(Cl)c2)c1C

PET-UNK-8df914d1-3
0.493

View
Cc1nnc(NC(=O)Cc2cccc(Cl)c2)n1C

JAG-UCB-a3ef7265-15
0.485

View
O=C(Cc1cccc(Cl)c1)Nc1nncs1

NAU-LAT-e1818702-10
0.484

View
O=C(Cc1cccc(Cl)c1)Nc1nncs1

JAN-GHE-5a013bed-7
0.484

View
Cc1cncc(NC(=O)Cc2cccc(Cl)c2)c1

EDG-MED-0da5ad92-12
0.478

View
O=C(Cc1cccc(Cl)c1)Nc1cccnc1

EDG-MED-0da5ad92-2
0.477

View
O=C(Cc1cccc(Cl)c1)Nc1nnn[nH]1

JAN-GHE-5a013bed-11
0.477

View
C=Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

AGN-NEW-c7b24fe3-1
0.471

View
O=C(Cc1cccc(Cl)c1)Nc1cnns1

JAN-GHE-5a013bed-6
0.469

View
O=C(Cc1cccc(Cl)c1)Nc1cncnc1

JAN-GHE-5a013bed-9
0.469

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

SAM-UNK-2684b532-13
0.463

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Cn1cnnc1NC(=O)Cc1cccc(Cl)c1

NAU-LAT-e1818702-7
0.463

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Cn1cnnc1NC(=O)Cc1cccc(Cl)c1

JAG-UCB-a3ef7265-17
0.463

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

ALP-POS-95b75b4d-8
0.463

View
Cn1cncc1NC(=O)Cc1cccc(Cl)c1

PET-UNK-8df914d1-4
0.463

View
Cc1c(N)cncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-3
0.457

View
N#Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

AGN-NEW-c7b24fe3-4
0.457

View
C#Cc1ncccc1NC(=O)Cc1cccc(Cl)c1

AGN-NEW-c7b24fe3-5
0.457

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1O

ALP-POS-95b75b4d-6
0.456

View
O=C(Cc1cccc(Cl)c1)Nc1cn[nH]c1

MIC-UNK-66895286-1
0.455

View
O=C(Cc1cccc(Cl)c1)Nc1cncc(Cl)c1Cl

JAN-GHE-5a013bed-10
0.448

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Cc1nnn(NC(=O)Cc2cccc(Cl)c2)c1C

JAN-GHE-5a013bed-1
0.448

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O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)F

SAM-UNK-2684b532-11
0.444

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NS(=O)(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

ALP-POS-95b75b4d-7
0.438

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NC(=O)c1ccncc1NC(=O)Cc1cccc(Cl)c1

ANN-UNI-98d2bf15-3
0.437

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Cc1ccncc1N(C)C(=O)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-1
0.437

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Cc1ccncc1N(C)C(=O)Cc1cccc(Cl)c1

JAN-GHE-83b26c96-15
0.437

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N#Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

MAK-UNK-6ca90168-23
0.431

View
Cc1ccncc1NC(=N)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-6
0.429

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O=C(Cc1cccc(Cl)c1)Nc1cnccc1-c1ccccc1

ALP-POS-0c2c77e1-1
0.427

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O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)(F)F

SAM-UNK-2684b532-12
0.425

View
O=C(Cc1cccc(Cl)c1)Nn1cnnc1

JAN-GHE-5a013bed-5
0.422

View
O=C(Cc1cccc(Cl)c1)Nc1cccc2[nH]ncc12

VLA-UCB-00f2c2b3-7
0.419

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O=C(Cc1cccc(Cl)c1)Nc1cnc2ccccc2c1

ALP-POS-3b848b35-3
0.419

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O=C(Cc1cccc(Cl)c1)Nc1cncc2ncccc12

MIC-UNK-08cd9c58-1
0.416

View
O=C(Cc1cccc(Cl)c1)Nc1ncn2ccccc12

EDJ-MED-50fe53e8-3
0.413

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1C1CC1

ALP-POS-95b75b4d-5
0.413

View
O=C(Cc1cccc(Cl)c1)Nc1cnc2ccccn12

PET-UNK-8df914d1-2
0.413

View
O=C(Cc1cccc(Cl)c1)Nc1nncn1C1CC1

NAU-LAT-e1818702-1
0.411

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O=C(Cc1cccc(Cl)c1)Nc1nncn1C1CC1

JAN-GHE-f4ca5a00-12
0.411

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1OCO2

EDJ-MED-a364e151-3
0.408

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O=C(Cc1cccc(Cl)c1)Nc1ncc2ccccn12

EDJ-MED-50fe53e8-4
0.408

View
O=C(Cc1cccc(Cl)c1)Nc1cncn1C1CC1

PET-UNK-8df914d1-5
0.405

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COc1ccc2cncc(NC(=O)Cc3cccc(Cl)c3)c2c1

EDJ-MED-00c1612e-1
0.400

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COc1ccc2cncc(NC(=O)Cc3cccc(Cl)c3)c2c1

PET-UNK-8df914d1-1
0.400

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2ccccc12

ADA-UCB-6c2cb422-1
0.400

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1CCCC2

EDJ-MED-a364e151-1
0.397

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1OCCO2

EDJ-MED-a364e151-2
0.397

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CCn1c(=O)n(CC(=O)Nc2c(C)ccnc2C)c2ccccc21

BAR-COM-0f94fc3d-51
0.392

View
O=C(Cc1cccc(Cl)c1)NC1CCNC1=O

MIC-UNK-42806bd5-1
0.391

View
O=C(Cc1cccc(Cl)c1)Nc1nncn1Cc1ccccc1

NAU-LAT-e1818702-9
0.390

View
O=C(Cc1cccc(Cl)c1)Nc1nncn1-c1ccccc1

NAU-LAT-e1818702-8
0.390

View
O=C(Cc1cccc(Cl)c1)Nc1nncc2ccccc12

EDJ-MED-50fe53e8-1
0.390

View
O=C(Cc1cccc(Cl)c1)Nc1cnnc2ccccc12

EDJ-MED-50fe53e8-2
0.390

View
Cc1ccnc(C)c1NC(=O)C(C)c1ccc(F)c(F)c1

BAR-COM-0f94fc3d-46
0.389

View
CC1(NC(=O)Cc2cccc(Cl)c2)CCNC1=O

MAT-POS-0bc33984-2
0.389

View
O=C1CC(NC(=O)Cc2cccc(Cl)c2)CN1

MIC-UNK-42806bd5-2
0.386

View
Cc1ccncc1N(CC#N)C(=O)Cc1cccc(Cl)c1

PET-UNK-bbe8d7ff-2
0.385

View
Cc1ccncc1N(CC=O)C(=O)Cc1cccc(Cl)c1

PET-UNK-bbe8d7ff-1
0.385

View
C=CC(=O)NN(C(=O)Cc1cccc(Cl)c1)c1cnccc1C

JAN-GHE-d851b096-1
0.383

View
Cc1ccncc1N(CC[C@@H](N)CO)C(=O)Cc1cccc(Cl)c1

BAR-COM-ebf5acce-10
0.381

View
O=C(Cc1cccc(Cl)c1)Nn1cn[nH]c1=O

JAN-GHE-5a013bed-4
0.380

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2[nH]c(=O)[nH]c12

MIC-UNK-8971c93c-1
0.380

View
Cc1ccncc1N(CNc1ncco1)C(=O)Cc1cccc(Cl)c1

BAR-COM-ebf5acce-7
0.379

View
CC1CCNC(=O)C1NC(=O)Cc1cccc(Cl)c1

MAT-POS-0bc33984-1
0.378

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1OCCC2

EDJ-MED-976da9a6-1
0.378

View
O=C(Cc1cccc(Cl)c1)Nc1cncc2c1CCCO2

EDJ-MED-976da9a6-2
0.378

View
Cc1ccncc1N(C[C@]1(C)C[C@@]1(C)N)C(=O)Cc1cccc(Cl)c1

BAR-COM-ebf5acce-9
0.373

View
O=C(Cc1cccc(Cl)c1)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-e1b5ac6b-1
0.372

View
Cc1ccncc1CC(=O)Nc1cccc(Cl)c1

EDJ-MED-49816e9b-1
0.370

View
Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.370

View
Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.370

View
Cc1ccnc(C)c1NC(=O)NCc1cccc(N2CCOCC2)c1

BAR-COM-0f94fc3d-33
0.369

View
Cc1ccncc1N(C(=O)Cc1cccc(Cl)c1)n1cnc(O)c1

BAR-COM-ebf5acce-2
0.369

View
O=C(Cc1cccc(Cl)c1)Nn1cnc2ccccc21

JAN-GHE-5a013bed-2
0.368

View
Cc1ccncc1N(C(=O)Cc1cccc(Cl)c1)c1ocnc1CO

BAR-COM-ebf5acce-8
0.368

View
O=C1CC(NC(=O)Cc2cccc(Cl)c2)C(=O)N1

MIC-UNK-fc94cdb5-1
0.366

View
Cc1ccncc1N(CC1(O)CC1)C(=O)Cc1cccc(Cl)c1

BAR-COM-ebf5acce-1
0.366

View
CC[C@@H](O)CN(C(=O)Cc1cccc(Cl)c1)c1cnccc1C

BAR-COM-ebf5acce-3
0.366

View
O=C(Cc1cccc(Cl)c1)NC1CCCNC1=O

MIC-UNK-4c7b8ba7-1
0.365

View
Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.365

View
O=C(Cc1cccc(Cl)c1)Nn1nncc1C1CC1

JAN-GHE-f4ca5a00-17
0.364

View
Cc1ccncc1N(CNc1ccon1)C(=O)Cc1cccc(Cl)c1

BAR-COM-ebf5acce-12
0.364

View
CC(=O)Nc1c(C)ccnc1NC(=O)CCl

RAF-SAT-b3ff87a1-4
0.364

View
Cc1ccncc1N(C[C@@H](O)CN)C(=O)Cc1cccc(Cl)c1

BAR-COM-ebf5acce-15
0.361

View
Cc1ccnc(C)c1NC(=O)C1CC2CC2C1

MAT-POS-590ac91e-20
0.358

View
Cc1ccncc1N(C[C@H](N)C(C)(C)O)C(=O)Cc1cccc(Cl)c1

BAR-COM-ebf5acce-6
0.357

View
CCCN(C(=O)Cc1cccc(Cl)c1)c1cccnc1

JAN-GHE-83b26c96-16
0.355

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

1.000

View
CC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.702

View
CC1=CC=NC(C)=C1NC(=O)CCC1=CC=CC(Cl)=C1

0.683

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(F)=C1

0.678

View
CC1=CC=C(CC(=O)NC2=C(C)C=CN=C2C)C=C1Cl

0.672

View
CC1=CC(C)=C(NC(=O)CC2=CC=CC(Cl)=C2)C(C)=N1

0.650

View
COC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.645

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(C(F)F)=C1

0.645

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC([N+](=O)[O-])=C1

0.645

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C(Cl)C(Cl)=C1

0.644

View
CC1=CC=CC(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.643

View
COCC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.635

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.635

View
CC1=CC=C(CC(=O)NC2=C(C)C=CN=C2C)C=C1Br

0.627

View
CCS(=O)(=O)C1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.625

View
CC1=CC=NC(C)=C1NC(=O)CSCC1=CC=CC(Cl)=C1

0.621

View
CC1=CC=NC(C)=C1NC(=O)COCC1=CC=CC(Cl)=C1

0.621

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C(Cl)C=C1

0.621

View
CC1=C(NC(=O)CC2=CC(OC(C)C)=CC=C2)C(C)=NC=C1

0.615

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(C2CC2)=C1

0.615

View
CC1=CC(Cl)=CC(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.614

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C(F)C(F)=C1

0.607

View
CC1=NOC(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.607

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(OC(F)F)=C1

0.606

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(OC(F)(F)F)=C1

0.606

View
CC1=CC=CC(Cl)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.600

View
CC1=CC=CC(O)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.600

View
CCCOC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.597

View
CC1=NC=CC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.597

View
CC1=CC(NC(=O)CC2=CC=CC(Cl)=C2)=CC=N1

0.597

View
COC1=CC(CC(=O)NC2=C(C)C=CN=C2C)=CC=C1C

0.597

View
CC1=CC=NC(C)=C1NC(=O)COC1=CC=CC(Cl)=C1

0.594

View
CC1=CC(C)=C(NC(=O)CC2=CC=CC(Cl)=C2)C(C)=C1

0.593

View
CC1=N[NH]C(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.590

View
CCC1=CC=CC(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.590

View
CNC(=O)COC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.588

View
COCCOC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.588

View
CC1=CC=NC(C)=C1NC(=O)CC1=CSC(CC2=CC=CC(Cl)=C2)=N1

0.587

View
CC1=CC=NC(C)=C1NC(=O)NCC1=CC=CC(Cl)=C1

0.585

View
CC1=CC=NC(C)=C1NC(=O)N1CCN(C(=O)CC2=CC=CC(Cl)=C2)CC1

0.583

View
CC1=CC=CC(F)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.581

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(OCC(F)(F)F)=C1

0.580

View
CC1=NC=CC(NC(=O)CC2=CC=CC(Cl)=C2)=C1Cl

0.578

View
CC1=CC(C)=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.576

View
CC1=C(NC(=O)C(C)CC2=CC=CC(Cl)=C2)C(C)=NC=C1

0.576

View
COC1=CC(CC(=O)NC2=C(C)C=CN=C2C)=CC=C1Cl

0.576

View
CC1=CC=NC(C)=C1NC(=O)CC1=C(Cl)C=CC=C1Cl

0.574

View
CC1=CC=CN=C1NC(=O)CC1=CC=CC(Cl)=C1

0.574

View
CC1=CC(Br)=CC(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.574

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C(Cl)C=C1Cl

0.571

View
O=C(CC1=CC=CC(Cl)=C1)NC1=C(F)N=CC=C1F

0.571

View
CC1=CC=CC(C(=O)O)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.571

View
CC1=NC=CC(NC(=O)CC2=CC=CC(Cl)=C2)=C1Br

0.569

View
CC1=C(NC(=O)N(C)CC2=CC=CC(Cl)=C2)C(C)=NC=C1

0.567

View
CC1=CC=NC(C)=C1NC(=O)NCCC1=CC=CC(Cl)=C1

0.567

View
CC1=CC=CC(Cl)=C1CC(=O)NC1=C(C)C=CN=C1C

0.565

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(NC(=O)OC(C)(C)C)=C1

0.563

View
CC(C)=CCOC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.563

View
CC=CCOC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.563

View
CC1=CC=NC(NC(=O)CC2=CC=CC(Cl)=C2)=N1

0.562

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C2C=CC=CC2=C1

0.561

View
CC1=CC=C(CC(=O)NC2=C(C)C=CN=C2C)C=C1

0.559

View
CC1=CC=NC(NC(=O)CC2=CC=CC(Cl)=C2)=C1

0.556

View
COC1=CC=C(CC(=O)NC2=C(C)C=CN=C2C)C=C1OC

0.554

View
CSC1=CC=CC(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.554

View
COC1=CC=CC(C)=C1NC(=O)CC1=CC=CC(Cl)=C1

0.554

View
CCN(CC1=CC=CC(Cl)=C1)C(=O)NC1=C(C)C=CN=C1C

0.551

View
CC1=C(NC(=O)N(CC2=CC=CC(Cl)=C2)C(C)C)C(C)=NC=C1

0.551

View
CC1=CC=CC(C)=C1CC(=O)NC1=C(C)C=CN=C1C

0.550

View
CCC1=CC=C(CC(=O)NC2=C(C)C=CN=C2C)C=C1

0.550

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(OCCCOC2=CC=CC=C2)=C1

0.548

View
CC1=CC=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1Cl

0.547

View
CC1=NC=CC(NC(=O)CC2=CC=CC(Cl)=C2)=N1

0.547

View
CC1=CC=NC(C)=C1NC(=O)CCSC1=CC=CC(Cl)=C1

0.544

View
CC1=CC=NC(C)=C1NC(=O)NCCCC1=CC=CC(Cl)=C1

0.543

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C(F)C=C1

0.541

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C(Br)C=C1

0.541

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC=C1Cl

0.540

View
COC1=CC(CC(=O)NC2=C(C)C=CN=C2C)=CC(OC)=C1

0.540

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.538

View
COC1=CC=C(Cl)C=C1CC(=O)NC1=C(C)C=CN=C1C

0.537

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C2CCCCC2=C1

0.537

View
CC1=C(NC(=O)CC2=CC=CC(Cl)=C2)C2=NC=NN2C=C1

0.535

View
CC1=CC=NC(C)=C1NC(=O)NCC(C)(C)CC1=CC=CC(Cl)=C1

0.535

View
CC1=CN=CC(CC(=O)NC2=C(C)C=CN=C2C)=C1

0.531

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C2OCCOC2=C1

0.529

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C2OCOC2=C1

0.529

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C2CCCC2=C1

0.529

View
CC1=CC=NC(C)=C1NC(=O)NCC(O)CC1=CC=CC(Cl)=C1

0.528

View
CC1=CC=NC(C)=C1NC(=O)C1=CC=CC(Cl)=C1

0.524

View
CC1=CC=NC(C)=C1NC(=O)CC1=C(F)C=CC=C1Cl

0.522

View
CC1=CC(C)=C(CC(=O)NC2=C(C)C=CN=C2C)C(C)=C1

0.516

View
COC1=CC=CC(OC)=C1CC(=O)NC1=C(C)C=CN=C1C

0.516

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C(C2=CC=CC=C2)C=C1

0.515

View
CC1=C(NC(=O)N(CCN(C)C)CC2=CC=CC(Cl)=C2)C(C)=NC=C1

0.514

View
CC1=CC=NC(C)=C1NC(=O)N1CCN(CC2=CC=CC(Cl)=C2)CC1

0.514

View
CC1=CC=NC(C)=C1NC(=O)N(CCCO)CC1=CC=CC(Cl)=C1

0.514

View
CC1=C(CC(=O)NC2=C(C)N=CC=C2C)C(C)=CC(Br)=C1

0.500

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=C(N2C=CC=C2)C=C1

0.500

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC(Cl)=C2OCCOC2=C1

0.500

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

0.538

View
Cc1ncccc1NC(=O)Cc1ccc(Cl)cc1

0.352

View
CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

0.321

View
Cc1ncccc1NC(=O)Cc1cccc(Cl)c1F

0.308

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)cc1

0.297

View
Clc1ccc(CC(=O)Nc2cccnc2)cc1Cl

0.280

View
C(NC1=C(C)N=C(C)C=C1C)(=O)CC1=CC=CC(Cl)=C1

0.897

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=CC(Cl)=C1

0.866

View
C(NC1=C(C)N=C(C)C=C1C)(=O)CC1=CC=C(Cl)C=C1

0.859

View
C(NC1=C(C)N=C(C)C=C1C)(=O)CC1=C(Cl)C=CC=C1

0.843

View
C(NC1=C(C)N=C(C)C=C1C)(CC1=CC=CC=C1)=O

0.827

View

Discussion:

Contributor: Ed J Griffen, MedChemica - Thu, 14 May 2020 21:49:57 +0000