Molecule Details

Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1
3-aminopyridine-like Enamine Mcule Assayed
View on Fragalysis x10247
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1
MW: 294.276
Fraction sp3: 0.2
HBA: 2
HBD: 1
Rotatable Bonds: 3
TPSA: 41.99
cLogP: 3.59002
Covalent Warhead:
Covalent Fragment:
Source
Enamine Extended REAL: s_22____3391102____59036
Mcule Ultimate: XYFCSWHALYQBPC-UHFFFAOYSA-N
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 23.988545
Average Inhibition @ 50 µM - Fluorescence: 49.125045
Average Inhibition @ 50 µM - RapidFire: 49.315057451583
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-05-26
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

JAN-GHE-83b26c96-14
1.000

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
1.000

View
Cc1ccncc1NC(=O)Cc1cccc(C(C)(F)F)c1

DAR-DIA-0cde14eb-79
0.806

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CCC(F)(F)c1cccc(CC(=O)Nc2cnccc2C)c1

DAR-DIA-0cde14eb-77
0.769

View
Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.683

View
Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.672

View
Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

ANN-UNI-98d2bf15-5
0.662

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Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.656

View
Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.656

View
Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.656

View
Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.646

View
COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.627

View
Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

ANN-UNI-98d2bf15-2
0.618

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Cc1ccncc1NC(=O)Cc1cccc(C#N)c1

TRY-UNI-714a760b-20
0.609

View
Cc1ccncc1NC(=O)Cc1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-2
0.606

View
Cc1ccncc1NC(=O)Cc1cccc(S(N)(=O)=O)c1

EDJ-MED-e58735b6-3
0.600

View
Cc1ccncc1NC(=O)Cc1cccc([S+](C)[O-])c1

DAR-DIA-0cde14eb-78
0.600

View
Cc1ccncc1NC(=O)Cc1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-1
0.592

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Cc1ccncc1NC(=O)Cc1cccc(C2CC2)c1

ALP-POS-95b75b4d-4
0.592

View
Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.587

View
Cc1ccncc1NC(=O)Cc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-3
0.575

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Cc1ccncc1NC(=O)Cc1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-4
0.575

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Cc1ccncc1NC(=O)Cc1cccc(-c2cn[nH]c2)c1

EDJ-MED-e58735b6-4
0.560

View
Cc1ccncc1NC(=O)Cc1cccc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-14
0.553

View
Cc1ccncc1NC(=O)Cc1cccc(CN2CCOCC2)c1

SAD-SAT-7d5528d9-1
0.545

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-7
0.538

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Cc1ccc(CC(=O)Nc2cnccc2C)cc1

JAN-GHE-83b26c96-11
0.538

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

BRU-LEF-c49414a7-1
0.538

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Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.522

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.522

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Cc1ccncc1NC(=O)Cc1ccsc1

MIH-UNI-6b9ca91a-1
0.515

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Cc1ccncc1NC(=O)CCc1cccc(F)c1

BEN-DND-93268d01-6
0.500

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Cc1ccncc1NC(=O)Cc1ccc2[nH]ncc2c1

VLA-UCB-00f2c2b3-2
0.500

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Cc1ccncc1NC(=O)Cc1ccc2[nH]ccc2c1

VLA-UCB-00f2c2b3-1
0.494

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(N)=O)c1

RAL-THA-6b94ceba-6
0.493

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Cc1ccncc1NC(=O)Cc1ccc(S(N)(=O)=O)cc1

GAB-REV-70cc3ca5-20
0.493

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Cc1ccncc1NC(=O)Cc1ccc2nc[nH]c2c1

GAB-REV-70cc3ca5-18
0.487

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Cc1ccncc1NC(=O)Cc1cncc(C#N)c1

TRY-UNI-2eddb1ff-1
0.486

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Cc1cc(CC(=O)Nc2cnccc2C)[nH]n1

EDJ-MED-c9f55a56-1
0.486

View
Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.484

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Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.484

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Cc1ccncc1NC(=O)Cc1ccccc1N

ANN-UNI-98d2bf15-1
0.479

View
COc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

MAT-POS-c9973a83-1
0.474

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Cc1ccncc1NC(=O)CC(C)(C)c1ccccc1

BEN-DND-93268d01-13
0.472

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Cc1nnc(CC(=O)Nc2cnccc2C)s1

ALE-HEI-f28a35b5-3
0.471

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CNS(=O)(=O)Cc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-16
0.468

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CNS(C)(=O)=O)c1

RAL-THA-6b94ceba-12
0.468

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Cc1ccncc1NC(=O)C(F)(F)c1cccc(Cl)c1

JAN-GHE-83b26c96-23
0.467

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O=C(Cc1cccc(Cl)c1)Nc1cnccc1C(F)(F)F

SAM-UNK-2684b532-12
0.467

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Cc1ccncc1NC(=O)CCCBr

ALE-HEI-f28a35b5-12
0.463

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Cc1ccncc1NC(=O)Cc1cnn(C2(F)CC2)c1

DAR-DIA-0cde14eb-63
0.462

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CNC(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-7
0.462

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(S(N)(=O)=O)c1

RAL-THA-6b94ceba-13
0.462

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Cc1ccncc1NC(=O)CNC(=O)Cc1cccnc1

GAB-REV-70cc3ca5-13
0.459

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CC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-5
0.456

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CS(N)(=O)=O)c1

RAL-THA-6b94ceba-15
0.456

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Cc1ccncc1NC(=O)CCc1ccccc1F

BEN-DND-93268d01-7
0.453

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Cc1ccncc1NC(=O)CCc1ccc(F)cc1

BEN-DND-93268d01-5
0.452

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Cc1ccncc1NC(=N)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-6
0.452

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(C)(=O)=O)c1

WIL-MOD-03b86a88-5
0.450

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(C)C(N)=O)c1

WIL-MOD-03b86a88-3
0.450

View
CNS(=O)(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-14
0.450

View
Cc1ccncc1NC(=O)Cc1cnn(C2(C)CC2)c1

DAR-DIA-0cde14eb-61
0.449

View
Cc1ccncc1NC(=O)Cc1cnn(C2(I)CC2)c1

DAR-DIA-0cde14eb-64
0.449

View
Cc1cccc(CC(=O)Nc2cnccc2C#N)c1

ALP-POS-95b75b4d-9
0.447

View
Cc1ccncc1NC(=O)CC1CC2(CC2)C1

MAT-POS-590ac91e-24
0.444

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

SAM-UNK-2684b532-13
0.444

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(N)(=O)=O)c1

WIL-MOD-03b86a88-6
0.444

View
COC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-8
0.444

View
O=C(Cc1cccc(Cl)c1)Nc1cnccc1Cl

ALP-POS-95b75b4d-8
0.444

View
Cc1ccncc1NC(=O)CCOC1CC1

MAT-POS-590ac91e-10
0.444

View
Cc1ccncc1NC(=O)Cc1cnn(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-62
0.443

View
Cc1ccncc1NC(=O)CC1(CO)CC1

MAT-POS-590ac91e-6
0.443

View
Cc1ccncc1NC(=O)CCCCC(=N)N

PET-SGC-6e7c5dc0-1
0.443

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)c(OC2CC(=O)N2)c1

RAL-THA-901e9a10-8
0.442

View
Cc1ccncc1NC(=O)CC(C)C(C)C

MAT-POS-590ac91e-11
0.441

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2nnc[nH]2)c1

RAL-THA-6b94ceba-10
0.440

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C2COC2)c1

WIL-MOD-03b86a88-2
0.439

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2ncc[nH]2)c1

RAL-THA-6b94ceba-9
0.439

View
Cc1ccncc1NC(=O)Cc1ccccc1-c1ccccn1

THO-SYG-cc9e9a11-2
0.438

View
Cc1ccncc1NC(=O)Cc1nc2cccc(C)c2o1

GAB-REV-70cc3ca5-23
0.438

View
COC1(CC(=O)Nc2cnccc2C)CC1

MAT-POS-590ac91e-9
0.437

View
Cc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-1
0.435

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2cnc[nH]2)c1

RAL-THA-6b94ceba-11
0.434

View
Cc1ccncc1NC(=O)Cc1cc(Cl)c2c(c1)OCCO2

BAR-COM-0f94fc3d-28
0.434

View
CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.433

View
CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.433

View
Cc1ccncc1NC(=O)CC1CC2CC2C1

MAT-POS-590ac91e-23
0.431

View
Cc1ccncc1NC(=O)CC1CCCCC1

ALE-HEI-f28a35b5-6
0.431

View
Cc1ccncc1NC(=O)CC1CCCCC1

TRY-UNI-714a760b-10
0.431

View
Cc1ccncc1NC(=O)CC1CCCCC1

EDG-MED-0da5ad92-4
0.431

View
CC(=O)Nc1ccc(NCC(=O)Nc2cnccc2C)cc1

GAB-REV-70cc3ca5-21
0.431

View
Cc1ccncc1NC(=O)Cc1cnn(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-74
0.427

View
Cc1ccncc1NC(=O)CCc1ccccn1

BEN-DND-93268d01-4
0.427

View
Cc1ccncc1NC(=O)CCSCCS(C)(=O)=O

MAK-UNK-372b0df5-3
0.427

View
Cc1ccncc1NC(=O)Cc1cc(F)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-2
0.425

View
Cc1ccncc1NC(=O)Cc1ccccc1Cc1ccccn1

THO-SYG-cc9e9a11-1
0.425

View
Cc1ccncc1NC(=O)Cc1nc2ccccc2[nH]1

GAB-REV-70cc3ca5-9
0.425

View
Cc1ccncc1NC(=O)CN1CCOCC1

BEN-DND-93268d01-10
0.425

View
Cc1ccncc1NC(=O)CCCCC(N)N

ALE-HEI-f28a35b5-10
0.425

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

1.000

View
CC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.694

View
CC1=CN=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.692

View
CC1=CC=NC=C1NC(=O)CCCC1=CC=CC(C(F)(F)F)=C1

0.686

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(I)=C1

0.683

View
O=C(CC1=CC=CC(C(F)(F)F)=C1)NC1=CN=CC=C1O

0.677

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(F)=C1

0.672

View
CC(=O)NC1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.662

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OC(F)(F)F)=C1

0.662

View
CC1=CN=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.662

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.656

View
COC1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.652

View
CSC1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.652

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC(F)(F)F)=C1

0.648

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Br)=C1

0.646

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C(F)(F)F)C=C1

0.641

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=NC=C1Br

0.636

View
O=C(CC1=CC=CC(C(F)(F)F)=C1)NC1=CC=NC=C1O

0.636

View
CC1=CC=NC=C1NC(=O)N(CC1=CC=CC(C(F)(F)F)=C1)C(C)C

0.634

View
CC1=CC(C(F)(F)F)=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.632

View
CCC1=CN=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.632

View
CC1=CC(Br)=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.632

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)F)=C1

0.632

View
O=C(CC1=CC=CC(C(F)(F)F)=C1)NC1=CC=NC=C1F

0.627

View
COC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.627

View
CC(C)(C)OC1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.625

View
CC1=CC=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.625

View
CC1=CC=NC=C1NC(=O)N(C)CC1=CC=CC(C(F)(F)F)=C1

0.625

View
CC1=CC(Cl)=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.623

View
CC1=CC=NC=C1NC(=O)NCC1=CC=CC(C(F)(F)F)=C1

0.620

View
CC1=CC=NC=C1NC(=O)C(O)CC1=CC=CC(C(F)(F)F)=C1

0.620

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=NC=C1I

0.618

View
CC1=CC=NC=C1NC(=O)C(=O)N(C)CC1=CC=CC(C(F)(F)F)=C1

0.616

View
CC(=O)C1=CN=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.614

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OC(F)F)=C1

0.614

View
CC1=CC=NC=C1NC(=O)C(C)CC1=CC=CC(C(F)(F)F)=C1

0.611

View
COCC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.609

View
CC1=CN=CC(C)=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.606

View
CC1=CSC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.606

View
CC1=NC=CN1C1=CC=NC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.605

View
CC1=CC(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)=C(C)C=N1

0.603

View
CC1=CC=C(F)C=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.603

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CN=CC(Cl)=C1Cl

0.603

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CN=CC=C1C1=CC=CC=C1

0.603

View
CC1=CC=NC=C1NC(=O)C(=O)NCC1=CC=CC(C(F)(F)F)=C1

0.603

View
CC1=CC=NC=C1NC(=O)CC(C)C1=CC=CC(C(F)(F)F)=C1

0.603

View
CC1=CN(C2=CC=NC=C2NC(=O)CC2=CC=CC(C(F)(F)F)=C2)N=C1

0.597

View
CN1CCN(C2=CC=NC=C2NC(=O)CC2=CC=CC(C(F)(F)F)=C2)CC1

0.597

View
CCCOC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.597

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CN=CC=C1N1C=CC=N1

0.595

View
CC1=CC=C(Br)C=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.594

View
CC1=NN=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.594

View
CC1=CC=NC=C1CNC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.592

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=CC2=CC=NC=C12

0.589

View
CC(C)C(=O)C1=CN=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.589

View
CC1=CC=C(C)C(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)=C1

0.588

View
CC1=CC=CC(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)=C1Cl

0.588

View
CC1=CC=NC=C1NC(=O)CC1=CC=CN=C1

0.587

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=NC=C1

0.585

View
N#CC1=CN=CC=C1NC(=O)CC1=CC(C(F)(F)F)=CC=C1

0.583

View
CC1=CC=NC=C1NC(=O)CNC1=CC=CC(C(F)(F)F)=C1

0.583

View
CC1=CC=NC=C1NC(=O)COC1=CC=CC(C(F)(F)F)=C1

0.583

View
CC1=CC=NC=C1NC(=S)NCC1=CC=CC(C(F)(F)F)=C1

0.583

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CN=CC=N1

0.582

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=CC2=CN=CC=C12

0.581

View
CC1=NC=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.580

View
CC1=CC=NC(C)=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.580

View
CC1=CC=C(CO)C=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.580

View
CC1=C(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)C=NN1C

0.580

View
CC1=CC=NC=C1NC(=O)N(CCN(C)C)CC1=CC=CC(C(F)(F)F)=C1

0.577

View
CC1=CC=NC=C1C(C)NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.575

View
CC1=CC=NC=C1CCNC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.575

View
CC1=CC=CC(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)=C1C

0.574

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=CN=C1

0.574

View
CC1=CC=C(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)C(C)=C1

0.574

View
CC1=CC=CC(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)=C1F

0.574

View
CC1=CC=NC=C1NC(=O)NCCCC1=CC=CC(C(F)(F)F)=C1

0.571

View
CC1=CC=C(Cl)C=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.571

View
CC1=CC=C(N)C=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.571

View
CC1=CC=C(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)C=C1NC(=O)C1=CC=NC=C1

0.570

View
CC1=CC=NC=C1NC(=O)CNS(=O)(=O)C1=CC=CC(C(F)(F)F)=C1

0.566

View
CC1=CC(O)=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.565

View
CC1=CC=NC=C1NC(=O)C1=CC=CC(C(F)(F)F)=C1

0.565

View
CC1=CC=CC(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)=C1O

0.565

View
CC1=CC=NC=C1NC(=O)C(=O)NCCCC1=CC=CC(C(F)(F)F)=C1

0.564

View
CC1=NC=C(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)C(C)=N1

0.563

View
CC1=CC=NC=C1NCC1=CC=CC(C(F)(F)F)=C1

0.559

View
CC1=CC=CC(NC(=O)CC2=CC=CC(C(F)(F)F)=C2)=C1Br

0.557

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CC=NC2=CC=NC=C12

0.553

View
CC1=CC=NC=C1NC(=O)N1CCN(CC2=CC=CC(C(F)(F)F)=C2)CC1

0.550

View
CC1=CC=NC=C1NC(=O)N1CC(CC2=CC=CC(C(F)(F)F)=C2)C1

0.550

View
CC1=NC(C(F)(F)F)=CC=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.549

View
CC1=CN=CC=C1CNC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.548

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC(C(F)(F)F)=C1

0.535

View
O=C(CC1=CC(C(F)(F)F)=CC=C1)NC1=CN=CC2=CC=CC=C12

0.533

View
CC1=CC=C(C(=O)N(C)C)C=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.533

View
CC1=CC=NC=C1NC(=O)C(=O)N1CCN(CC2=CC=CC(C(F)(F)F)=C2)CC1

0.530

View
CC1=CC=C(C2=CC=NN2C)C=C1NC(=O)CC1=CC=CC(C(F)(F)F)=C1

0.519

View
CC1=CC=C(C(F)(F)F)C=C1NC(=O)CC1=CC=CN=C1

0.459

View
CC1=CC(C(F)(F)F)=CC=C1NC(=O)CC1=CC=CN=C1

0.458

View
Cc1ccncc1NC(=O)Cc1cccc(c1)C#N

0.609

View
Cc1ccncc1NC(=O)Cc1ccccc1

0.587

View
FC(F)(F)c1cccc(CC(=O)Nc2cccnc2)c1

0.574

View
Cc1ccncc1NC(=O)Cc1ccc(F)cc1

0.545

View
FC(F)(F)c1ccc(CC(=O)Nc2cccnc2)cc1

0.325

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

1.000

View
C(NC1=C(Cl)C=CN=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.677

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=C(C(F)(F)F)C=C1

0.641

View
C(NC1=C(C(OC)=O)C=CN=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.634

View
C(NC1=CN=CC(C#N)=C1C)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.597

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.592

View
C(NC1=C(C)C(OC)=CN=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.583

View
C(NC1=CC=CN=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.574

View
C(NC1C(C)=C(C)C(C)=NC=1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.563

View
C(NC1=C(F)N=CC=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.551

View
C(NC1=C(C)C(Br)=C(C)N=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.541

View
C(NC1=C(Cl)N=CC=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.535

View
C(NC1=C(C)N=C(C)C=C1C)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.528

View
C(NC1=C(C)C=C(C)N=C1Cl)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.514

View
C(NC1=CN=C(F)C=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.500

View
C(NC1=CN=C(Br)C=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.500

View
C(NC1=CN=C(C#C)C=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.493

View
C(NC1=CN=C(Cl)C=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.493

View
C(NC1=CN=C(C#N)C=C1)(=O)CC1=CC=CC(C(F)(F)F)=C1

0.474

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1=CC=C(C(F)(F)F)C=C1

0.350

View

Discussion: