Molecule Details

Cc1ccncc1NC(=O)Cc1cncc(C#N)c1
3-aminopyridine-like Assayed
View on Fragalysis x10314
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)Cc1cncc(C#N)c1
MW: 252.1
Fraction sp3: 0.14
HBA: 4
HBD: 1
Rotatable Bonds: 3
TPSA: 78.67
cLogP: 1.84
Covalent Warhead:
Covalent Fragment: ✔️
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 35.51632
Average Inhibition @ 50 µM - Fluorescence: 42.149045
Average Inhibition @ 50 µM - RapidFire: 22.867788855
Relative Solubility @ 20 µM: 1.01
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-06-10
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.641

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.641

View
Cc1ccncc1NC(=O)Cc1cccc(C#N)c1

TRY-UNI-714a760b-20
0.632

View
N#Cc1cncc(CC(=O)Nc2cccnc2)c1

DAR-DIA-23aa0b97-17
0.551

View
CCNc1ncc(C#N)cc1CC(=O)Nc1cnccc1C

TRY-UNI-1fd04853-1
0.547

View
CCNc1ncc(C#N)cc1CC(=O)Nc1cnccc1C

PET-SGC-175e168c-1
0.547

View
Cc1ccc(CC(=O)Nc2cnccc2C)cc1

JAN-GHE-83b26c96-11
0.538

View
Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.538

View
Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.536

View
Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.532

View
Cc1ccncc1NC(=O)Nc1cncc(C#N)c1

CHR-SOS-363cfb78-2
0.521

View
Cc1ccncc1NC(=O)Cc1ccsc1

MIH-UNI-6b9ca91a-1
0.515

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.514

View
Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.514

View
Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.514

View
COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.514

View
Cc1ccncc1NC(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-3
0.512

View
Cc1ccncc1NC(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-6
0.512

View
Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.507

View
Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.507

View
Cc1ccncc1NC(=O)Cc1cccc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-14
0.494

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(N)=O)c1

RAL-THA-6b94ceba-6
0.493

View
Cc1ccncc1NC(=O)Cc1ccc(S(N)(=O)=O)cc1

GAB-REV-70cc3ca5-20
0.493

View
Cc1nnc(CC(=O)Nc2cnccc2C)s1

ALE-HEI-f28a35b5-3
0.493

View
Cc1ccncc1NC(=O)CN(C)c1cccc(C#N)c1

GAB-REV-70cc3ca5-19
0.487

View
Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

ANN-UNI-98d2bf15-5
0.487

View
Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

ANN-UNI-98d2bf15-2
0.486

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

JAN-GHE-83b26c96-14
0.486

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

DAR-DIA-0cde14eb-76
0.486

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
0.486

View
Cc1cc(CC(=O)Nc2cnccc2C)[nH]n1

EDJ-MED-c9f55a56-1
0.486

View
Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.484

View
Cc1ccncc1NC(=O)Cc1cnn(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-74
0.481

View
CNC(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-7
0.481

View
Cc1ccncc1NC(=O)Cc1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-2
0.481

View
Cc1ccncc1NC(=O)Cc1cc(C#N)ccc1-c1ccccn1

THO-SYG-cc9e9a11-4
0.476

View
COc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

MAT-POS-c9973a83-1
0.474

View
Cc1ccncc1NC(=O)Cc1cccc([S+](C)[O-])c1

DAR-DIA-0cde14eb-78
0.474

View
Cc1ccncc1NC(=O)Cc1cccc(C(C)(F)F)c1

DAR-DIA-0cde14eb-79
0.474

View
Cc1ccncc1NC(=O)Cc1cccc(S(N)(=O)=O)c1

EDJ-MED-e58735b6-3
0.474

View
Cc1ccncc1NC(=O)Cc1cc(C#N)ccc1Cc1ccccn1

THO-SYG-cc9e9a11-3
0.471

View
CNS(=O)(=O)Cc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-16
0.468

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(C)(=O)=O)c1

WIL-MOD-03b86a88-5
0.468

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(C)C(N)=O)c1

WIL-MOD-03b86a88-3
0.468

View
Cc1ccncc1NC(=O)Cc1cccc(C2CC2)c1

ALP-POS-95b75b4d-4
0.468

View
Cc1ccncc1NC(=O)Cc1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-1
0.468

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Cc1ccncc1NC(=O)CCCBr

ALE-HEI-f28a35b5-12
0.463

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COC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-8
0.463

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(N)(=O)=O)c1

WIL-MOD-03b86a88-6
0.463

View
Cc1ccncc1NC(=O)Cc1ccc2[nH]ncc2c1

VLA-UCB-00f2c2b3-2
0.462

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CCNc1ncc(C#N)cc1NC(=O)Nc1cnccc1C

TRY-UNI-1fd04853-2
0.462

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(S(N)(=O)=O)c1

RAL-THA-6b94ceba-13
0.462

View
Cc1ccncc1NC(=O)CC1(C#N)CCC1

MAT-POS-590ac91e-15
0.458

View
Cc1ccncc1NC(=O)Cc1ccccc1N

ANN-UNI-98d2bf15-1
0.458

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C2COC2)c1

WIL-MOD-03b86a88-2
0.457

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2ncc[nH]2)c1

RAL-THA-6b94ceba-9
0.457

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CS(N)(=O)=O)c1

RAL-THA-6b94ceba-15
0.456

View
CC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-5
0.456

View
Cc1ccncc1NC(=O)Cc1ccc2[nH]ccc2c1

VLA-UCB-00f2c2b3-1
0.456

View
CCC(F)(F)c1cccc(CC(=O)Nc2cnccc2C)c1

DAR-DIA-0cde14eb-77
0.456

View
Cc1ccncc1NC(=O)Cc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-3
0.456

View
Cc1ccncc1NC(=O)Cc1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-4
0.456

View
Cc1ccncc1NC(=O)Cc1cc(C#N)ccc1CN1CCC(O)CC1

TRY-UNI-9f475305-1
0.455

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2cnc[nH]2)c1

RAL-THA-6b94ceba-11
0.451

View
Cc1ccncc1NC(=O)Cc1ccc2nc[nH]c2c1

GAB-REV-70cc3ca5-18
0.450

View
CNS(=O)(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-14
0.450

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CNS(C)(=O)=O)c1

RAL-THA-6b94ceba-12
0.450

View
Cc1ccncc1NC(=O)Cc1cnn(C2(I)CC2)c1

DAR-DIA-0cde14eb-64
0.449

View
Cc1ccncc1NC(=O)Cc1cnn(C2(C)CC2)c1

DAR-DIA-0cde14eb-61
0.449

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-7
0.446

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

BRU-LEF-c49414a7-1
0.446

View
Cc1ccncc1NC(=O)Cc1cccc(-c2cn[nH]c2)c1

EDJ-MED-e58735b6-4
0.444

View
Cc1ccncc1NC(=O)CCCCC(N)N

ALE-HEI-f28a35b5-10
0.444

View
Cc1ccncc1NC(=O)Cc1cc(C#N)ccc1CNC(=O)N1CCOCC1

PET-SGC-276eba5a-1
0.444

View
C#Cc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-4
0.443

View
Cc1ccncc1NC(=O)Cc1cnn(C2(F)CC2)c1

DAR-DIA-0cde14eb-63
0.443

View
Cc1ccncc1NC(=O)Cc1cnn(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-62
0.443

View
Cc1ccncc1NC(=O)CCCCC(=N)N

PET-SGC-6e7c5dc0-1
0.443

View
Cc1ccncc1NC(=O)CC1(CO)CC1

MAT-POS-590ac91e-6
0.443

View
Cc1ccncc1NC(=O)CC(C)C(C)C

MAT-POS-590ac91e-11
0.441

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2nnc[nH]2)c1

RAL-THA-6b94ceba-10
0.440

View
Cc1ccncc1NC(=O)CNC(=O)Cc1cccnc1

GAB-REV-70cc3ca5-13
0.440

View
CCCCOc1ccc(Cl)cc1CC(=O)Nc1cnccc1C

EDG-MED-0da5ad92-7
0.439

View
CCNc1ncc(C#N)cc1C(=O)Nc1cnccc1C

SAD-SAT-cefd50cc-10
0.438

View
Cc1ccncc1NC(=O)Nc1cccc(C#N)c1

TRY-UNI-714a760b-24
0.434

View
Cc1ccncc1NC(=O)Cc1cc(Cl)c2c(c1)OCCO2

BAR-COM-0f94fc3d-28
0.434

View
Cc1ccncc1NC(=O)Cc1cccc(CN2CCOCC2)c1

SAD-SAT-7d5528d9-1
0.434

View
Cc1ccncc1NC(=O)Cc1cc(N2CCCCC2)cc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-29
0.433

View
CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.433

View
CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.433

View
Cc1ccncc1NC(=O)CCc1ccc(F)cc1

BEN-DND-93268d01-5
0.432

View
Cc1ccncc1NC(=O)Cc1cc(N2CCCCC2)cc(C2(F)CC2)c1

DAR-DIA-0cde14eb-18
0.432

View
C=CC(=O)N1CCOC(c2cc(C#N)ccc2CC(=O)Nc2cnccc2C)C1

TRY-UNI-9f475305-9
0.429

View
N#Cc1cccc(CC(=O)Nc2cnccc2C#N)c1

SAD-SAT-24589cd1-5
0.429

View
Cc1ccncc1NC(=O)CN1CCOCC1

BEN-DND-93268d01-10
0.425

View
Cc1ccncc1NC(=O)CCOC1CC1

MAT-POS-590ac91e-10
0.425

View
Cc1ccncc1NC(=O)CC1CC2(CC2)C1

MAT-POS-590ac91e-24
0.425

View
Cc1ccncc1NC(=O)CCc1cccc(F)c1

BEN-DND-93268d01-6
0.423

View
Cc1ccncc1NC(=O)Cc1cccc2c1CNCC2

ADA-UCB-6c2cb422-4
0.422

View
Cc1ccncc1NC(=O)CC1CCCNC1

EDG-MED-0da5ad92-9
0.421

View
CC1=CN=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.651

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C#N)C=C1

0.641

View
CC1=CC=NC=C1NC(=O)CC1=CN=CC(O)=C1

0.641

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.583

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1C

0.569

View
CC1=CC=NC=C1NC(=O)CC1=CN=CN=C1

0.562

View
CC1=CC=NC=C1NC(=O)CC1=CC=CN=C1

0.562

View
CC1=CC=NC=C1NC(=O)CC1=CC=NC=C1

0.556

View
CC1=CC(C)=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.554

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(I)C=C1

0.545

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=N1

0.545

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(OCC#N)C=C1

0.542

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.538

View
CC(=O)NC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.537

View
CC1=CC=NC=C1NC(=O)CC1=CC=C([N+](=O)[O-])C=C1

0.536

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(I)=C1

0.536

View
CC1=CC=NC=C1NC(=O)CCC1=CC=C(C#N)C=C1

0.535

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(O)C=C1

0.530

View
CCC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.530

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Br)C=C1

0.530

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1O

0.529

View
CC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1Br

0.529

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C(N)=O)C=C1

0.529

View
CC1=CC(C)=C(CC(=O)NC2=CN=CC=C2C)C(C)=C1

0.522

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C=C1

0.522

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(F)C=C1

0.522

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(CN)C=C1

0.522

View
CC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.522

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)C(Cl)=C1

0.522

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC(OC)=C1

0.522

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(OCC#N)=C1

0.519

View
CC1=CC=NC=C1NC(=O)CC1=CSC=C1

0.515

View
CC(=O)C1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.515

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C(C)(C)C)C=C1

0.515

View
CC1=CC=NC=C1NC(=O)CC1=COC=C1

0.515

View
CC1=CC=NC=C1NC(=O)CC1=CC=C([Si](C)(C)C)C=C1

0.515

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(F)C(F)=C1

0.514

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.514

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C)C([N+](=O)[O-])=C1

0.514

View
COC1=CC=CC(CC(=O)NC2=CN=CC=C2C)=C1

0.514

View
CC1=CC=NC=C1NC(=O)CN

0.508

View
CC1=CC=NC=C1NC(=O)CC1=C(C)C=CC=C1C

0.507

View
CCCC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.507

View
COC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.507

View
CC1=CC=NC=C1NC(=O)CC1=CN(C)N=C1

0.507

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(Cl)N=C1

0.507

View
CC1=CC=NC=C1NC(=O)CNC1=CC=C(C#N)C=C1

0.507

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Br)=C1

0.507

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(F)=C1

0.507

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC=C1C

0.507

View
COC1=CC(CC(=O)NC2=CN=CC=C2C)=CC(OC)=C1OC

0.507

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC([N+](=O)[O-])=C1

0.507

View
CC1=CC=NC=C1NC(=O)CC1=NOC(C)=C1C#N

0.507

View
CC1=CC=NC=C1NC(=O)CSCC1=CC=C(C#N)C=C1

0.507

View
CC1=CC=NC=C1NC(=O)COC1=CC=C(C#N)C=C1

0.500

View
CC1=CC=NC=C1NC(=O)CC1=CN=C2C=CC=CC2=C1

0.500

View
CC1=CC=NC=C1NC(=O)CCCC#N

0.500

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(OCCCC#N)C=C1

0.500

View
CC1=CC=NC=C1NC(=O)CNC1=CC=C(C#N)C=N1

0.500

View
CC1=CC=NC=C1NC(=O)CNC(=O)C1=CC=C(C#N)C=C1

0.500

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(CC(C)C)C=C1

0.500

View
CC1=CC=NC=C1NC(=O)CC1=C(C)C=C(N(C)C)C=C1C

0.500

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC=C1CC#N

0.500

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C(F)(F)F)C=C1

0.500

View
COC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1OC

0.493

View
CC1=CN=CC=C1CC(=O)NC1=CN=CC=C1C

0.493

View
CC1=CC=NC=C1NC(=O)COC1=CC=CC(C#N)=C1

0.487

View
CC1=CC=NC=C1NC(=O)CSC1=CC=C(C#N)C=C1

0.486

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2C=CC=CC2=C1

0.486

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(C2=CC=CC=C2)C=C1

0.486

View
CCCCC1=CC=C(CC(=O)NC2=CN=CC=C2C)C=C1

0.486

View
CC1=CC=NC=C1NC(=O)CCCCC#N

0.486

View
CC1=CC=NC=C1NC(=O)CS(=O)(=O)CC1=CC=C(C#N)C=C1

0.481

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2CCCCC2=C1

0.480

View
CC1=CC=NC=C1NC(=O)C1=CC=C(C#N)C=C1

0.478

View
CC1=CC=NC=C1NC(=O)CC1=CC=C2CCCC2=C1

0.474

View
CC1=CN=CC(CC(=O)NC2=CC(C#N)=CC=C2C)=C1

0.473

View
CC1=CC=NC=C1NC(=O)CC1=C(C)N(C)N=C1C

0.472

View
CC1=CC=NC=C1NC(=O)CCCCCC#N

0.472

View
CC1=CC=NC=C1NC(=O)CC1=CC=C(N2C=CC=C2)C=C1

0.467

View
CC1=CC=NC=C1NC(=O)C1=NC=C(C#N)C=C1C

0.466

View
CC1=CC=NC=C1NC(=O)NCC1=CC=CC(C#N)=C1

0.462

View
CC1=CC=NC=C1NC(=O)NCC1=CC=C(C#N)C=C1

0.453

View
CC1=CC=NC=C1NC(=O)C(=O)NCC1=CC=CC(C#N)=C1

0.450

View
CC1=CN=CC(CC(=O)NC2=CC=NC=C2C#N)=C1

0.447

View
CC1=CC=NC=C1NC(=O)C1=CC(C#N)=C[NH]1

0.446

View
CC1=CC=NC=C1NC(=O)N(C)CC1=CC=CC(C#N)=C1

0.444

View
CC1=CC=C(C#N)C=C1NC(=O)CC1=CC=CN=C1

0.440

View
CC1=CC=NC=C1NC(=O)NCCC1=CC=CC(C#N)=C1

0.439

View
CNC1=CC=C(C#N)C=C1NC(=O)CC1=CC(C)=CN=C1

0.436

View
CC1=CN=CC(CC(=O)NC2=CC=NC=C2C)=C1

0.431

View
CC1=CC=C(C#N)C=C1NC(=O)CC1=CC=NC=C1

0.419

View
CC1=CN=CC=C1NC(=O)CC1=CC=C(C#N)C=C1

0.419

View
CC1=CC=C(C#N)C=C1NC(=O)CC1=CN=CN=C1

0.413

View
CC1=CC=NC=C1NC(=O)CC(C)C1=CC=NC=C1

0.405

View
CNC1=CC=C(C#N)C=C1NC(=O)CC1=CC=CN=C1

0.397

View
CC1=CN=CC=C1CC(=O)NC1=CC(C#N)=CC=C1C

0.397

View
CNC1=CC=C(C#N)C=C1NC(=O)CC1=CC=NC=C1C

0.378

View
CNC1=CC=C(C#N)C=C1NC(=O)CC1=CC=NC=C1

0.372

View
CC1=CC(C)=C(CC(=O)NC2=CC=NC=C2C#N)C(C)=C1

0.362

View
Cc1ccncc1NC(=O)Cc1cccc(c1)C#N

0.632

View
O=C(Cc1cncc(c1)C#N)Nc1cccnc1

0.551

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=CN=C1

0.562

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=NC=C1

0.556

View
C(NC1=C(C)C=CN=C1)(=O)CC1C=CC=C(C)C=1

0.522

View
C(NC1=C(C)C=CN=C1)(=O)CC1=C(Cl)N=CC=C1

0.446

View
C(NC1=CN=CC(C#N)=C1C)(=O)CC1=CC=CN=C1

0.403

View
C(NC1=CN=CC(C#N)=C1C)(=O)CC1=CC=NC=C1

0.395

View
C(NC1=CN=CC(C#N)=C1C)(=O)CC1C=CC=C(C)C=1

0.354

View
C(NC1=CN=CC(C#N)=C1C)(=O)CCC1=CC=CN=C1

0.345

View
C(NC1=CN=CC(Cl)=C1C)(=O)CC1=CC=CN=C1

0.329

View
C(NC1=C(C)C(OC)=CN=C1)(=O)CC1=CC=CN=C1

0.329

View
C(NC1=CN=CC(C#N)=C1C)(=O)CC1=C(Cl)N=CC=C1

0.310

View
C(NC1C(C)=C(C)C(C)=NC=1)(=O)CC1=CC=CN=C1

0.300

View
C(NC1=CC=CN=C1)(=O)CC1=CC=CN=C1

0.257

View


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