Molecule Details

Cc1ccncc1NC(=O)CC1(CO)CC1
3-aminopyridine-like Enamine Ordered
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)CC1(CO)CC1
MW: 220.12
Fraction sp3: 0.5
HBA: 3
HBD: 2
Rotatable Bonds: 4
TPSA: 62.22
cLogP: 1.49
Covalent Warhead:
Covalent Fragment:
Source
Enamine REAL: Z1461811319
Enamine Extended REAL: s_22____3391102____7101322
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: synthesis in progress
CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

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COC1(CC(=O)Nc2cnccc2C)CC1

MAT-POS-590ac91e-9
0.632

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Cc1ccncc1NC(=O)CC1(C#N)CCC1

MAT-POS-590ac91e-15
0.600

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Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.566

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Cc1ccncc1NC(=O)CC12CCCC1C2

MAT-POS-590ac91e-25
0.562

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Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.542

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CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.540

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CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.540

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Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.536

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Cc1ccncc1NC(=O)CCCBr

ALE-HEI-f28a35b5-12
0.534

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Cc1ccncc1NC(=O)CC1CC2(CC2)C1

MAT-POS-590ac91e-24
0.532

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Cc1ccc(CC(=O)Nc2cnccc2C)cc1

JAN-GHE-83b26c96-11
0.517

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Cc1ccncc1NC(=O)CC(C)C(C)C

MAT-POS-590ac91e-11
0.508

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CNC(=O)COC1(CC(=O)Nc2cnccc2C)CCN(C)CC1

SIM-DEM-2d7ee9fd-1
0.507

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Cc1ccncc1NC(=O)CC(O)C1CC1

MAT-POS-590ac91e-7
0.500

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Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.500

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CC(=O)N1CCN(CC(=O)Nc2cnccc2C)CC1

BEN-DND-93268d01-8
0.500

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Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.500

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Cc1ccncc1NC(=O)CC(C)(C)c1ccccc1

BEN-DND-93268d01-13
0.492

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Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.492

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Cc1ccncc1NC(=O)Cc1ccsc1

MIH-UNI-6b9ca91a-1
0.492

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Cc1ccncc1NC(=O)CC1CCCCC1

TRY-UNI-714a760b-10
0.492

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Cc1ccncc1NC(=O)CN1CCCCC1

BEN-DND-93268d01-11
0.492

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Cc1ccncc1NC(=O)CN1CCN(C)CC1

BEN-DND-93268d01-9
0.492

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Cc1nnc(CC(=O)Nc2cnccc2C)s1

ALE-HEI-f28a35b5-3
0.492

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Cc1ccncc1NC(=O)CC1CCCCC1

ALE-HEI-f28a35b5-6
0.492

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CC(=O)Nc1ccc(NCC(=O)Nc2cnccc2C)cc1

GAB-REV-70cc3ca5-21
0.492

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Cc1ccncc1NC(=O)CC1CCCCC1

EDG-MED-0da5ad92-4
0.492

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Cc1ccncc1NC(=O)CC1CC2CC2C1

MAT-POS-590ac91e-23
0.492

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CC(=O)NCCN1CCC(CNS(C)(=O)=O)(CC(=O)Nc2cnccc2C)CC1

SIM-DEM-163f01e0-1
0.487

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Cc1ccncc1NC(=O)CC1(c2cccc(S(N)(=O)=O)c2)CCC1

CHR-SOS-e960e883-6
0.487

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Cc1ccncc1NC(=O)Cc1cnn(C2(I)CC2)c1

DAR-DIA-0cde14eb-64
0.486

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Cc1ccncc1NC(=O)Cc1cnn(C2(C)CC2)c1

DAR-DIA-0cde14eb-61
0.486

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Cc1ccncc1NC(=O)Cc1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-1
0.486

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Cc1ccncc1NC(=O)CCc1ccccn1

BEN-DND-93268d01-4
0.485

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Cc1cc(CC(=O)Nc2cnccc2C)[nH]n1

EDJ-MED-c9f55a56-1
0.484

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Cc1ccncc1NC(=O)CCOC1CC1

MAT-POS-590ac91e-10
0.484

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Cc1ccncc1NC(=O)CN1CCOCC1

BEN-DND-93268d01-10
0.484

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Cc1ccncc1NC(=O)CCCCC(=N)N

PET-SGC-6e7c5dc0-1
0.484

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Cc1ccncc1NC(=O)Cc1cnn(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-62
0.479

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Cc1ccncc1NC(=O)Cc1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-2
0.479

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Cc1ccncc1NC(=O)Cc1cnn(C2(F)CC2)c1

DAR-DIA-0cde14eb-63
0.479

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Cc1ccncc1NC(=O)Cc1ccccc1N

ANN-UNI-98d2bf15-1
0.477

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Cc1ccncc1NC(=O)CCc1ccn[nH]1

MAT-POS-590ac91e-17
0.477

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Cc1ccncc1NC(=O)CC1(c2cccc(S(N)(=O)=O)c2)CCCC1

CHR-SOS-e960e883-5
0.474

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Cc1ccncc1NC(=O)Cc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-3
0.472

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Cc1ccncc1NC(=O)Cc1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-4
0.472

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CC(=O)N1CCCN(CC(=O)Nc2cnccc2C)CC1

BEN-DND-6de5dfa0-6
0.471

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Cc1ccncc1NC(=O)Cc1cccc([S+](C)[O-])c1

DAR-DIA-0cde14eb-78
0.471

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CCC(=O)N1CCN(CC(=O)Nc2cnccc2C)CC1

BEN-DND-6de5dfa0-1
0.471

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Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.470

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Cc1ccncc1NC(=O)CCc1ccc(F)cc1

BEN-DND-93268d01-5
0.470

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Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.470

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Cc1ccncc1NC(=O)Cc1ccc(S(N)(=O)=O)cc1

GAB-REV-70cc3ca5-20
0.470

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Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.470

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CC(C(=O)Nc1cnccc1C)=C1CC1

ERI-UCB-5b47150d-4
0.467

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Cc1ccncc1NC(=O)CNC1(c2ccccc2)CCCCC1

WAR-XCH-e55cba98-11
0.466

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(C)C(N)=O)c1

WIL-MOD-03b86a88-3
0.466

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C=CC(=O)Nc1cnccc1C

MAK-UNK-6ca90168-27
0.464

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Cc1ccncc1NC(=O)CN1CCCC1=O

BEN-DND-22e6b372-4
0.463

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Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.463

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Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.463

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Cc1ccncc1NC(=O)CC1(c2cccc(S(N)(=O)=O)c2)CCCCC1

CHR-SOS-e960e883-4
0.463

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Cc1ccncc1NC(=O)C(CO)c1ccccc1

BEN-DND-93268d01-3
0.462

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Cc1ccncc1NC(=O)CCCCC(N)N

ALE-HEI-f28a35b5-10
0.462

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Cc1ccncc1NC(=O)Cc1cnn(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-74
0.459

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CC(=O)N[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-13
0.459

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CC(=O)NC1CCN(CC(=O)Nc2cnccc2C)CC1

BEN-DND-6de5dfa0-14
0.457

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Cc1ccncc1NC(=O)CN1CCN(S(C)(=O)=O)CC1

BEN-DND-6de5dfa0-3
0.456

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Cc1ccncc1NC(=O)CN1CCN(C)C(=O)C1

BEN-DND-6de5dfa0-5
0.456

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Cc1ccncc1NC(=O)CC1CCCNC1

EDG-MED-0da5ad92-9
0.456

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Cc1ccncc1NC(=O)Cc1cccc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-14
0.453

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Cc1ccncc1NC(=O)Nc1ccccc1

TRY-UNI-714a760b-4
0.452

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Cc1ccncc1NC(=O)Nc1ccccc1

ALE-HEI-f28a35b5-1
0.452

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CC(=O)N(C)C1CCN(CC(=O)Nc2cnccc2C)CC1

BEN-DND-6de5dfa0-15
0.451

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Cc1ccncc1NC(=O)CN1CCCCC1=O

BEN-DND-22e6b372-3
0.449

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Cc1ccncc1NC(=O)CCc1ccccc1F

BEN-DND-93268d01-7
0.449

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Cc1ccncc1NC(=O)CN1CCNC(=O)C1

BEN-DND-6de5dfa0-4
0.449

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COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.449

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NC23CC(C2)C3)c1

MAT-POS-e501d84c-1
0.447

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Cc1ccncc1NC(=O)C1CCC12CCC2

MAT-POS-590ac91e-22
0.446

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CC(=O)N1CCN(CC(=O)Nc2cnccc2C)C(=O)C1

BEN-DND-22e6b372-1
0.444

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Cc1ccncc1NC(=O)Cc1cccc(C2CC2)c1

ALP-POS-95b75b4d-4
0.444

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Cc1ccncc1NC(=O)Cc1cncc(C#N)c1

TRY-UNI-2eddb1ff-1
0.443

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Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
0.443

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Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

DAR-DIA-0cde14eb-76
0.443

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Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

JAN-GHE-83b26c96-14
0.443

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Cc1ccncc1NC(=O)CCc1cccc(Cl)c1

ALP-POS-f13221e1-4
0.443

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Cc1ccncc1NC(=O)CN1CCN(C(=O)CCl)CC1

BEN-DND-6de5dfa0-16
0.443

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CCOC(=O)N1CCN(CC(=O)Nc2cnccc2C)CC1

BEN-DND-6de5dfa0-7
0.443

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Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

ANN-UNI-98d2bf15-2
0.443

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Cc1ccncc1NC(=O)CCSCCS(C)(=O)=O

MAK-UNK-372b0df5-3
0.441

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Cc1ccncc1NC(=O)C12CC(CO1)C2

MAT-POS-590ac91e-4
0.439

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Cc1ccncc1NC(=O)Cc1ccccc1Cc1ccccn1

THO-SYG-cc9e9a11-1
0.438

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Cc1ccncc1NC(=O)Cc1ccc2[nH]ncc2c1

VLA-UCB-00f2c2b3-2
0.438

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Cc1ccncc1NC(=O)Cc1cccc(C#N)c1

TRY-UNI-714a760b-20
0.437

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Cc1ccncc1NC(=O)CN1CCN(C)CC1=O

BEN-DND-22e6b372-2
0.437

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Cc1ccncc1NC(=O)CCc1cccc(F)c1

BEN-DND-93268d01-6
0.437

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Cc1ccncc1NC(=O)NCCBr

ALE-HEI-f28a35b5-13
0.435

View
Cc1ccncc1NC(=O)CNC(=O)Cc1cccnc1

GAB-REV-70cc3ca5-13
0.435

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Cc1ccncc1NC(=O)C12CCC(CO1)C2

MAT-POS-590ac91e-29
0.435

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Cc1ccncc1NC(=O)CC1(CO)CCC1

0.902

View
Cc1ccncc1NC(=O)CC1(CC(=O)O)CC1

0.791

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Cc1ccncc1NC(=O)CC1(CN)CC1

0.767

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Cc1ccncc1NC(=O)CC1(CC(=O)Nc2cnccc2C)CCCC1

0.762

View
Cc1ccncc1NC(=O)CC1(CC(=O)Nc2cnccc2C)CCCCC1

0.744

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CSCC1(CC(=O)Nc2cnccc2C)CC1

0.733

View
COCC1(CC(=O)Nc2cnccc2C)CC1

0.733

View
Cc1cnccc1NC(=O)CC1(CO)CCC1

0.733

View
Cc1ccncc1NC(=O)CC1(CS(C)(=O)=O)CC1

0.717

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COC(=O)CC1(CC(=O)Nc2cnccc2C)CC1

0.717

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Cc1ccncc1NC(=O)CC1(C)CC1

0.698

View
Cc1ccncc1NC(=O)NCC1(CO)CC1

0.696

View
Cc1ccncc1NC(=O)C(=O)NCC1(CO)CC1

0.696

View
Cc1ccncc1NC(=O)CC1(O)CCCC1

0.689

View
Cc1ccncc1NC(=O)CC1(O)CCC1

0.689

View
Cc1ccncc1NC(=O)CCC1(CCC(=O)Nc2cnccc2C)CC1

0.682

View
Cc1ccncc1NC(=O)CC1(CN)CCCCC1

0.681

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O=C(CC1(CO)CCC1)Nc1cnccc1O

0.674

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Cc1ccncc1NC(=O)CC1(O)CCCCC1

0.674

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Cc1ccncc1NC(=O)CC1(C#N)CC1

0.674

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Cc1ccncc1NC(=O)N1CCC(CO)(CO)CC1

0.674

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Cc1ccncc1NC(=O)CC1(CSc2ccccc2)CC1

0.673

View
Cc1ccncc1NC(=O)CC1(C)CCCC1

0.667

View
Cc1ccncc1NC(=O)CCC1(CC(=O)Nc2cnccc2C)CCCCC1

0.667

View
Cc1ccncc1NC(=O)CC1(CNC(=O)OC(C)(C)C)CC1

0.667

View
Cc1ccncc1NC(=O)NCCC1(CO)CC1

0.667

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Cc1ccncc1NC(=O)CO

0.659

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CC(=O)NCC1(CC(=O)Nc2cnccc2C)CCCCC1

0.653

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COc1ccncc1NC(=O)CC1(CO)CCC1

0.653

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CSc1ccncc1NC(=O)CC1(CO)CCC1

0.653

View
Cc1ccncc1NC(=O)CC1(C)CCCCC1

0.652

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Cc1ccncc1NC(=O)CC1(N)CCC1

0.652

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Cc1ccncc1NC(=O)NC1CC(CO)(CO)C1

0.646

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Cc1ccncc1NC(=O)C1(CO)CC1

0.644

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CC(C)(C)Oc1ccncc1NC(=O)CC1(CO)CCC1

0.640

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Cc1ccncc1NC(=O)CC1(C(F)(F)F)CC1

0.638

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COC1(CC(=O)Nc2cnccc2C)CCC1

0.638

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Cc1ccncc1NC(=O)CC1(C#N)CCCCC1

0.633

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Cc1ccncc1NC(=O)NCC1(CO)CCC1

0.633

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CCC1(CO)CCN(C(=O)Nc2cnccc2C)CC1

0.633

View
Cc1ccncc1NC(=O)NCC1(CO)CCCC1

0.633

View
Cc1ccncc1NC(=O)C(=O)NCC1(CO)CCC1

0.633

View
Cc1ccncc1NC(=O)C(=O)NCC1(CO)CCCC1

0.633

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COCC1(CC(=O)Nc2cnccc2C)CCOCC1

0.627

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Cc1ccc(-c2ccncc2)cc1NC(=O)CC1(CO)CCC1

0.627

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O=C(CC1(CO)CCC1)Nc1ccncc1I

0.625

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Cc1ccncc1NC(=O)CC1(C(=O)Nc2cnccc2C)CCCCC1

0.625

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Cc1nccn1-c1ccncc1NC(=O)CC1(CO)CCC1

0.623

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Cc1ccncc1NC(=O)NCC1(CO)CCCCC1

0.620

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Cc1ccncc1NC(=O)C(=O)NCC1(CO)CCCCC1

0.620

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Cc1ccncc1NC(=O)CC12CC3CC(CC(C3)C1)C2

0.617

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Cc1ccncc1NC(=O)CC1(C)CC1(Cl)Cl

0.617

View
Cc1ccncc1NC(=O)NC1(CO)CC1

0.617

View
Cc1ccncc1NC(=O)N1CC(C)(CO)C1

0.617

View
Cc1cnccc1NC(=O)CC1(CN)CC1

0.617

View
Cc1ccc(-c2cccnc2)cc1NC(=O)CC1(CO)CCC1

0.611

View
Cc1ccccc1NC(=O)CC1(CO)CCC1

0.609

View
Cc1cnccc1NC(=O)CC1(CC(=O)Nc2ccncc2C)CCCC1

0.609

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O=C(CC1(CO)CCC1)Nc1cnccc1-c1ccccc1

0.608

View
Cc1ccncc1NC(=O)NCCC1(CO)CCC1

0.608

View
Cc1ccncc1NC(=O)N1CCC(CO)(CCO)C1

0.608

View
Cc1ccncc1NC(=O)CC1(O)CCCNC1

0.608

View
Cc1ccncc1NC(=O)Cc1ccc(CC(=O)Nc2cnccc2C)cc1

0.605

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Cc1ccc(O)cc1NC(=O)CC1(CO)CCC1

0.604

View
Cc1ccncc1NC(=O)CCC1(O)CCC1

0.604

View
Cc1ccncc1NC(=O)N1CCC(C)(CO)CC1

0.604

View
Cc1ccncc1NC(=O)N1C[C@@](C)(CO)[C@@](C)(CO)C1

0.604

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Cc1ccncc1NC(=O)C(=O)NC1(CO)CC1

0.604

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Cc1ccncc1NC(=O)CC1(CC(=O)Nc2nccs2)CCCCC1

0.604

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CN1CCN(c2ccncc2NC(=O)CC2(CO)CCC2)CC1

0.604

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Cc1ccncc1NC(=O)CC1CC1

0.600

View
Cc1ccncc1NC(=O)CC1(CNC(=O)OC(C)(C)C)CCCCC1

0.600

View
Cc1ccncc1CNC(=O)CC1(CO)CCC1

0.600

View
Cc1ccncc1NC(=O)CC1(N)CCSC1

0.600

View
Cc1ccncc1NC(=O)CC1(O)CCCN(C)C1

0.596

View
Cc1ccncc1NC(=O)NCC1(CO)CCOCC1

0.596

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Cc1ccncc1NC(=O)NCC1(CO)CC2(CCC2)C1

0.596

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COCC1(CO)CCN(C(=O)Nc2cnccc2C)C1

0.596

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CCCC1(CO)CCN(C(=O)Nc2cnccc2C)C1

0.596

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Cc1ccncc1NC(=O)C(=O)NCC1(CO)CCOCC1

0.596

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CCC1(CO)CCN(C(=O)C(=O)Nc2cnccc2C)CC1

0.596

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Cc1ccncc1NC(=O)C(=O)NCC1(CO)CC2(CCC2)C1

0.596

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Cc1ccncc1NC(=O)C(=O)NCCC1(CO)CCC1

0.596

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Cc1ccc(C)c(NC(=O)CC2(CO)CCC2)c1

0.596

View
Cc1ccncc1NC(=O)CCC1(C)CC1

0.596

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Cc1cnccc1NC(=O)CC1(CC(=O)Nc2ccncc2C)CCCCC1

0.596

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Cc1ccncc1NC(=O)CN

0.595

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Cc1ccncc1NC(=O)CCl

0.595

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Cc1ccncc1NC(=O)CC1(CC(=O)N2CCOCC2)CCCC1

0.593

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Cc1ccncc1NC(=O)CC1CCC(C)(C)CC1

0.592

View
CSCC1(CC(=O)Nc2ccncc2C)CC1

0.592

View
COCC1(CC(=O)Nc2ccncc2C)CC1

0.592

View
Cc1ccncc1NC(=O)NC1(CO)CCCC1

0.592

View
Cc1ccncc1NC(=O)NC1(CO)CCC1

0.592

View
Cc1ccncc1NC(=O)N1CCC(O)(CO)CC1

0.592

View
Cc1ccncc1NC(=O)N(C)C1(CO)CC1

0.592

View
Cc1ccncc1NC(=O)Cc1ccncc1

0.591

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O=C(CC1(CO)CCC1)Nc1ccnc2ccncc12

0.588

View
Cc1ccncc1NC(=O)NCC1(CO)COC1

0.588

View
Cc1ccncc1NC(=O)Cc1ccc(O)cc1

0.587

View
O=C(CC1CC1)Nc1cnccc1CO

0.098

View
COC(C)(C)CC(=O)Nc1cnccc1C

0.180

View
Cc1ccncc1NC(=O)CCC1CCCC1

0.176

View
CC(=O)CCCC(=O)Nc1cnccc1C

0.172

View
CC1(C)C[C@@H]1C(=O)Nc1cnccc1CO

0.156

View
CCC(C)C(C)C(=O)Nc1cnccc1CO

0.152

View
Cc1ccncc1N(C)C(=O)CC1(C)CC1

0.119

View
C(NC1=C(C)C=CN=C1)(=O)CC1CC1

0.849

View
C(NC1=C(C)C=CN=C1)(=O)CC(C)(C)C

0.829

View
C(NC1=C(C)C=CN=C1)(=O)CC(CC)C

0.826

View
C(NC1=C(C)C=CN=C1)(CC1CCOC1)=O

0.817

View
C(NC1=C(C)C=CN=C1)(=O)CCC(C)C

0.791

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