Molecule Details

Cc1ccncc1NC(=O)Cc1ccccc1-c1ccccn1
3-aminopyridine-like
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)Cc1ccccc1-c1ccccn1
MW: 303.14
Fraction sp3: 0.11
HBA: 3
HBD: 1
Rotatable Bonds: 4
TPSA: 54.88
cLogP: 3.63
Covalent Warhead:
Covalent Fragment:
CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8

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O=C(Cc1ccccc1-c1ccccn1)Nc1cnccc1CO

THO-SYG-cc9e9a11-6
0.690

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Cc1ccncc1NC(=O)Cc1cc(C#N)ccc1-c1ccccn1

THO-SYG-cc9e9a11-4
0.654

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Cc1ccncc1NC(=O)Cc1ccccc1Cc1ccccn1

THO-SYG-cc9e9a11-1
0.566

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Cc1ccncc1NC(=O)Cc1ccccc1N

ANN-UNI-98d2bf15-1
0.549

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Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.500

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Cc1ccncc1NC(=O)CCc1ccccn1

BEN-DND-93268d01-4
0.493

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Cc1cc(CC(=O)Nc2cnccc2C)[nH]n1

EDJ-MED-c9f55a56-1
0.493

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Cc1ccncc1NC(=O)Cc1cc(C#N)ccc1Cc1ccccn1

THO-SYG-cc9e9a11-3
0.477

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Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.471

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Cc1ccncc1NC(=O)Cc1ccccc1CN1CCC(O)CC1

SAM-UNK-2684b532-9
0.471

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Cc1ccncc1NC(=O)Cc1cccc2c1CNCC2

ADA-UCB-6c2cb422-4
0.464

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Cc1ccncc1NC(=O)CCc1ccccc1F

BEN-DND-93268d01-7
0.462

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Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.461

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Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.461

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Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.461

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Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.461

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Cc1nnc(CC(=O)Nc2cnccc2C)s1

ALE-HEI-f28a35b5-3
0.459

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Cc1ccc(CC(=O)Nc2cnccc2C)cc1

JAN-GHE-83b26c96-11
0.458

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Cc1ccncc1NC(=O)Cc1nc2ncccc2o1

GAB-REV-70cc3ca5-11
0.458

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Cc1ccncc1NC(=O)Cc1cccc(C2CC2)c1

ALP-POS-95b75b4d-4
0.457

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Cc1ccncc1NC(=O)Cc1cccc(C(N)=O)c1

ANN-UNI-98d2bf15-2
0.456

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Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.455

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Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.455

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N#Cc1ccc(-c2ccccn2)c(CC(=O)Nc2cnccc2CO)c1

THO-SYG-cc9e9a11-8
0.449

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Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.448

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Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.447

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Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.447

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Cc1ccncc1NC(=O)Cc1cccc([S+](C)[O-])c1

DAR-DIA-0cde14eb-78
0.444

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Cc1ccncc1NC(=O)Cc1cccc(S(N)(=O)=O)c1

EDJ-MED-e58735b6-3
0.444

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COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.443

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Cc1ccncc1NC(=O)Cc1ccc(S(N)(=O)=O)cc1

GAB-REV-70cc3ca5-20
0.442

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CCNc1ncc(C#N)cc1CC(=O)Nc1cnccc1C

PET-SGC-175e168c-1
0.440

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CCNc1ncc(C#N)cc1CC(=O)Nc1cnccc1C

TRY-UNI-1fd04853-1
0.440

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Cc1ccncc1NC(=O)Cc1ccsc1

MIH-UNI-6b9ca91a-1
0.440

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Cc1ccncc1NC(=O)Cc1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-1
0.439

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Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

JAN-GHE-83b26c96-14
0.438

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Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
0.438

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Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

DAR-DIA-0cde14eb-76
0.438

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Cc1ccncc1NC(=O)Cc1nc2ccccc2[nH]1

GAB-REV-70cc3ca5-9
0.434

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Cc1ccncc1NC(=O)Cc1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-2
0.434

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Cc1ccncc1NC(=O)CCCCC(=N)N

PET-SGC-6e7c5dc0-1
0.432

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Cc1ccncc1NC(=O)CC1(CO)CC1

MAT-POS-590ac91e-6
0.432

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Cc1ccncc1NC(=O)Cc1cccc(C#N)c1

TRY-UNI-714a760b-20
0.432

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Cc1ccncc1NC(=O)CC(C)C(C)C

MAT-POS-590ac91e-11
0.431

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Cc1ccncc1NC(=O)CCCBr

ALE-HEI-f28a35b5-12
0.431

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CCCCOc1ccc(Cl)cc1CC(=O)Nc1cnccc1C

EDG-MED-0da5ad92-7
0.430

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Cc1ccncc1NC(=O)Cc1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-4
0.429

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Cc1ccncc1NC(=O)Cc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-3
0.429

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CC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-5
0.429

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Cc1ccncc1NC(=O)Cc1nc2cccc(C)c2o1

GAB-REV-70cc3ca5-23
0.429

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Cc1ccncc1NC(=O)Cc1cccc(C(C)(F)F)c1

DAR-DIA-0cde14eb-79
0.427

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Cc1ccncc1NC(=O)CC(O)C1CC1

MAT-POS-590ac91e-7
0.427

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Cc1ccncc1NC(=O)Nc1ccccc1

TRY-UNI-714a760b-4
0.425

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Cc1ccncc1NC(=O)Nc1ccccc1

ALE-HEI-f28a35b5-1
0.425

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CNS(C)(=O)=O)c1

RAL-THA-6b94ceba-12
0.424

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Cc1ccncc1NC(=O)Cc1ccc2nc[nH]c2c1

GAB-REV-70cc3ca5-18
0.424

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Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

ANN-UNI-98d2bf15-5
0.422

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Cc1ccncc1NC(=O)Cc1cnn(C2(I)CC2)c1

DAR-DIA-0cde14eb-64
0.422

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Cc1ccncc1NC(=O)CCNC(=O)c1ccccc1F

PET-SGC-2e937068-1
0.422

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Cc1ccncc1NC(=O)Cc1cncc(C#N)c1

TRY-UNI-2eddb1ff-1
0.420

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Cc1ccncc1NC(=O)Cc1cccc(-c2cn[nH]c2)c1

EDJ-MED-e58735b6-4
0.419

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COC(=O)NCc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-8
0.419

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Cc1ccncc1NC(=O)Cc1cnn(C2(F)CC2)c1

DAR-DIA-0cde14eb-63
0.417

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(S(N)(=O)=O)c1

RAL-THA-6b94ceba-13
0.417

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Cc1ccncc1NC(=O)CC1CC2(CC2)C1

MAT-POS-590ac91e-24
0.416

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C2COC2)c1

WIL-MOD-03b86a88-2
0.414

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Cc1ccncc1NC(=O)Cc1cccc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-14
0.414

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Cc1ccncc1NC(=O)Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-4
0.413

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CCC(F)(F)c1cccc(CC(=O)Nc2cnccc2C)c1

DAR-DIA-0cde14eb-77
0.412

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Cc1ccncc1NC(=O)Cc1ccc2[nH]ccc2c1

VLA-UCB-00f2c2b3-1
0.412

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(CS(N)(=O)=O)c1

RAL-THA-6b94ceba-15
0.412

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COc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

MAT-POS-c9973a83-1
0.410

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Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(N)=O)c1

RAL-THA-6b94ceba-6
0.410

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Cc1ccncc1NC(=O)Cc1cccc(CN2CCOCC2)c1

SAD-SAT-7d5528d9-1
0.409

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COC1(CC(=O)Nc2cnccc2C)CC1

MAT-POS-590ac91e-9
0.408

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COc1ccc(-c2csc(CC(=O)Nc3cnccc3C)n2)cc1

GAB-REV-70cc3ca5-15
0.407

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CNS(=O)(=O)Cc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-16
0.407

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Cc1ccncc1NC(=O)CC(C)(C)c1ccccc1

BEN-DND-93268d01-13
0.405

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Cc1ccncc1NC(=O)Cc1cnn(C2(C)CC2)c1

DAR-DIA-0cde14eb-61
0.405

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Cc1ccncc1NC(=O)Nc1ccccc1CCNS(C)(=O)=O

SIM-DEM-f31d0e65-1
0.405

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Cc1ccncc1NC(=O)CCc1cccc(Cl)c1

ALP-POS-f13221e1-4
0.402

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Cc1ccncc1NC(=O)CCc1cc(S(N)(=O)=O)ccc1Br

PET-SGC-83d43576-1
0.402

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CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.400

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CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.400

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Cc1ccncc1NC(=O)Cc1ccc2[nH]ncc2c1

VLA-UCB-00f2c2b3-2
0.400

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Cc1ccncc1NC(=O)Cc1cnn(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-62
0.400

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CNC(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-7
0.400

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Cc1ccncc1NC(=O)Nc1ccccc1CN1CCC(O)CC1

SAM-UNK-2684b532-8
0.398

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(-c2ncc[nH]2)c1

RAL-THA-6b94ceba-9
0.398

View
Cc1ccncc1NC(=O)CCc1cccc(F)c1

BEN-DND-93268d01-6
0.398

View
Cc1ccncc1NC(=O)CN1CCOCC1

BEN-DND-93268d01-10
0.397

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Cc1ccncc1NC(=O)CCOC1CC1

MAT-POS-590ac91e-10
0.397

View
Cc1ccncc1NC(=O)CCCCC(N)N

ALE-HEI-f28a35b5-10
0.397

View
CC(=O)NCCc1c[nH]c2c(CC(=O)Nc3cnccc3C)cc(F)cc12

PET-SGC-1c3a473d-1
0.396

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NCC(C)(C)C#N)c1

MAT-POS-044491d2-7
0.396

View
Cc1ccncc1NC(=O)CNC(=O)Cc1cccnc1

GAB-REV-70cc3ca5-13
0.395

View
Cc1ccncc1NC(=O)Cc1cc(Cl)c2c(c1)OCCO2

BAR-COM-0f94fc3d-28
0.393

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NC23CC(C2)C3)c1

MAT-POS-e501d84c-1
0.393

View
CC(=O)N1CCN(CC(=O)Nc2cnccc2C)CC1

BEN-DND-93268d01-8
0.392

View
Cc1ccncc1NC(=O)CCc1ccn[nH]1

MAT-POS-590ac91e-17
0.392

View
Cc1ccncc1NC(=O)Cc1ccccc1CO

0.702

View
Cc1ccccc1CC(=O)Nc1cnccc1C

0.696

View
Cc1ccncc1NC(=O)Cc1cccnc1C

0.688

View
CCc1ccccc1CC(=O)Nc1cnccc1C

0.667

View
Cc1ccncc1NC(=O)Cc1cccnc1Br

0.660

View
Cc1ccncc1NC(=O)Cc1ccccc1F

0.653

View
Cc1ccncc1NC(=O)Cc1ccccc1Cl

0.653

View
Cc1ccncc1NC(=O)Cc1ccccc1I

0.653

View
Cc1ccncc1NC(=O)Cc1ccccc1Br

0.653

View
Cc1ccncc1NC(=O)Cc1ccccc1C(F)(F)F

0.647

View
COc1ccccc1CC(=O)Nc1cnccc1C

0.640

View
CC(=O)Nc1ccccc1CC(=O)Nc1cnccc1C

0.640

View
Cc1ccncc1NC(=O)Cc1cccc2cccnc12

0.635

View
Cc1ccncc1NC(=O)Cc1cccc2ccccc12

0.627

View
CSc1ccccc1CC(=O)Nc1cnccc1C

0.627

View
Cc1ccncc1NC(=O)Cc1csc(-c2ccccn2)n1

0.625

View
Cc1ccncc1NC(=O)c1cccc(-c2ccccn2)c1C

0.623

View
Cc1cnccc1CC(=O)Nc1cnccc1C

0.617

View
Cc1ccncc1NC(=O)Cc1ccccc1NS(C)(=O)=O

0.615

View
Cc1ccncc1NC(=O)Cc1ccccc1CC#N

0.615

View
Cc1ccncc1NC(=O)Cc1ccccc1S(C)=O

0.615

View
CCSc1ccccc1CC(=O)Nc1cnccc1C

0.615

View
C#Cc1ccccc1CC(=O)Nc1cnccc1C

0.615

View
Cc1ccncc1NC(=O)Cc1ccccc1S(C)(=O)=O

0.615

View
Cc1ccncc1NC(=O)Cc1cccc(F)c1F

0.608

View
Cc1ccncc1NC(=O)Cc1cccc(C)c1Cl

0.608

View
Cc1ccncc1NC(=O)Cc1ccccc1[N+](=O)[O-]

0.604

View
COC(=O)c1ccccc1CC(=O)Nc1cnccc1C

0.604

View
Cc1ccncc1NC(=O)Cc1ccccc1OC1CCCC1

0.600

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1Cl

0.596

View
Cc1ccncc1NC(=O)Cc1cccc(Br)c1C

0.596

View
Cc1ccncc1NC(=O)Cc1ccccc1OC(C)C

0.593

View
Cc1ccncc1NC(=O)Cc1ccccc1COC(C)C

0.593

View
Cc1ccncc1NC(=O)Cc1cnccc1Cl

0.592

View
Cc1cnccc1CC(=O)Nc1c[nH]nc1-c1ccccn1

0.589

View
Cc1ccccc1CC(=O)Nc1cnccc1O

0.588

View
Cc1ccncc1CC(=O)Nc1ccccc1CC(F)(F)F

0.585

View
Cc1ccncc1NC(=O)Cc1ccccc1OC(F)F

0.582

View
Cc1ccncc1NC(=O)Cc1c[nH]c2ncccc12

0.582

View
Cc1ccncc1NC(=O)CCc1ccccn1

0.577

View
Cc1ccncc1NC(=O)CCC(=O)c1ccccn1

0.577

View
Cc1ccncc1NC(=O)Cc1ccc(CC(=O)Nc2cnccc2C)cc1

0.574

View
Cc1ccncc1NC(=O)Cc1c[nH]c2ccccc12

0.574

View
Cc1ccncc1NC(=O)Cc1cn(C)c2ccccc12

0.574

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1F

0.574

View
Cc1ccncc1NC(=O)Cc1ccnc(O)c1Br

0.574

View
Cc1cnccc1CC(=O)Nc1nnc(-c2ccccn2)[nH]1

0.571

View
Cc1ccncc1NC(=O)Cc1c(C)cccc1C

0.571

View
Cc1ccncc1NC(=O)Cc1ccccc1NC(=O)OC(C)(C)C

0.571

View
Cc1ccncc1NC(=O)Cc1ccccc1C(=O)OC(C)(C)C

0.571

View
Cc1ccc(C)c(CC(=O)Nc2cnccc2C)c1

0.569

View
Cc1ccccc1CCC(=O)Nc1cnccc1C

0.569

View
Cc1cnccc1NC(=O)Cc1ccccc1CO

0.569

View
Cc1ccccc1CC(=O)Nc1cnccc1-c1ccccc1

0.566

View
Cc1ncccc1CC(=O)Nc1cnccc1O

0.566

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)nc1C

0.566

View
Cc1ccncc1NC(=O)Cc1ncccc1F

0.566

View
Cc1ncccc1CC(=O)Nc1cnccc1-c1ccccc1

0.564

View
CCn1cc(CC(=O)Nc2cnccc2C)c2ccccc21

0.564

View
Cc1ccncc1NC(=O)Cc1coc2ccccc12

0.564

View
Cc1ccncc1NC(=O)Cc1ccncc1

0.562

View
Cc1cnccc1CC(=O)Nc1ccccc1C

0.560

View
Cc1ccncc1NC(=O)Cc1ccc(O)cc1

0.560

View
Cc1ccncc1NC(=O)Cc1cccnc1

0.560

View
Cc1ccccc1CC(=O)Nc1ccncc1C

0.560

View
CCc1ccccc1NC(=O)Cc1cnccc1C

0.558

View
Cc1ccncc1NC(=O)Cc1ccc(-c2ccccc2)cc1

0.558

View
Cc1ccncc1NC(=O)CN1C(=O)c2ccccc2C1=O

0.558

View
Cc1ccncc1NC(=O)Cc1cc(F)c(F)cc1F

0.558

View
Cc1ccncc1NC(=O)Cc1cncc(O)c1

0.558

View
Cc1ccncc1NC(=O)Cc1cnn(C)c1C

0.558

View
Cc1cnccc1NC(=O)Cc1cccnc1C

0.558

View
Cc1ccccc1CC(=O)Nc1ccncc1O

0.558

View
Cc1cnccc1NC(=O)Cc1ccccc1O

0.558

View
Cc1ccncc1NC(=O)CCCc1ccccn1

0.556

View
Cc1ccncc1NC(=O)CCSc1ccccn1

0.556

View
Cc1ccncc1NC(=O)CN1Cc2ccccc2C1=O

0.554

View
Cc1ccncc1NC(=O)Cc1cccc([N+](=O)[O-])c1C

0.554

View
COc1ccc(C(=O)Nc2cnccc2C)cc1-c1ccccn1

0.552

View
Cc1ccncc1NC(=O)c1ccccn1

0.551

View
Cc1ccncc1NC(=O)CCc1nc(-c2ccccn2)no1

0.550

View
O=C(Cc1ccccc1CO)Nc1cnccc1O

0.549

View
Cc1ccncc1NC(=O)Cc1ncc[nH]1

0.549

View
CC(=O)Nc1ccncc1NC(=O)Cc1ccccc1C

0.547

View
Cc1ccncc1NC(=O)Cc1cccc(I)c1

0.547

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)cn1

0.547

View
Cc1cc(Br)ccc1CC(=O)Nc1cnccc1C

0.547

View
Cc1ccncc1NC(=O)Cc1c[nH]c2cnccc12

0.547

View
Cc1ccncc1NC(=O)CSCc1ccccn1

0.545

View
Cc1ccncc1NC(=O)CN1CCc2ccccc21

0.545

View
Cc1ccncc1NC(=O)Cc1ccc(Br)cc1O

0.545

View
Cc1ccncc1NC(=O)Cc1cnc2ccccc2c1

0.545

View
COc1cccnc1CC(=O)Nc1cnccc1C

0.545

View
Cc1ccncc1NC(=O)COCc1ccccn1

0.545

View
Cc1ccccc1CC(=O)Nc1c[nH]nc1-c1ccccn1

0.545

View
Cc1ccncc1CC(=O)Nc1ccccc1C(C)(F)F

0.545

View
Cc1ccncc1NC(=O)NNC(=O)Cc1ccccn1

0.545

View
Cc1ccncc1NC(=O)Nc1c[nH]nc1-c1ccccn1

0.545

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Cc1ccncc1NC(=O)C(=O)Nc1c[nH]nc1-c1ccccn1

0.545

View
Cc1ccncc1NC(=O)CNC(=O)Cc1cccc2ccccc12

0.544

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C(NC1=CC=C(C2=CC=CC=C2)N=C1)(=O)CC1=C(C)C=CC=C1

0.818

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C(NC1=C(C2=C(C)C=CC=C2)N=CC=C1)(=O)CC1=CC=NC=C1

0.813

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C(NC1=C(C2=C(C)C=CC=C2)N=CC=C1)(=O)CC1=C(C)C=CC=C1

0.801

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C(NC1=C(C2=C(C)C=CC=C2)N=CC=C1)(=O)CC1=CC=CC=C1

0.801

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C(NC1=C(C2=C(C)C=CC=C2)N=CC=C1)(=O)CC1=CC=C(C)C=C1

0.775

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