Molecule Details

Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1
3-aminopyridine-like Enamine Mcule Assayed
View on Fragalysis x10422
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1
MW: 288.778
Fraction sp3: 0.25
HBA: 2
HBD: 1
Rotatable Bonds: 3
TPSA: 41.99
cLogP: 3.95972
Covalent Warhead:
Covalent Fragment:
Source
Enamine Extended REAL: s_22____3391102____5183200
Mcule: MCULE-9013689716
Activity Data
IC50 (µM) - Fluorescence: 96.9383202483582
IC50 (µM) - RapidFire: 24.522808858117
Trypsin IC50 (µM): 99.0
pIC50 (µM) - Fluorescence 4.01350451002268
Average Inhibition @ 20 µM - Fluorescence: 49.325525
Average Inhibition @ 50 µM - Fluorescence: 67.95416
Average Inhibition @ 50 µM - RapidFire: 66.91403689
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-06-10
Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-10
1.000

View
Cc1ccncc1NC(=O)C(C)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-18
0.710

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Cc1ccncc1NC(=O)C(F)(F)c1cccc(Cl)c1

JAN-GHE-83b26c96-23
0.662

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CCC(O)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

BAR-COM-0f94fc3d-38
0.632

View
CC(=O)Nc1cnccc1C(C)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-9
0.587

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Cc1ccncc1OCCNC(=O)C(C)(C)c1cccc(Cl)c1

WIL-UNI-2e73223c-4
0.539

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Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)C(C)C

JAN-GHE-83b26c96-9
0.521

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Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

TRY-UNI-714a760b-12
0.515

View
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

JAG-UCB-cedd89ab-8
0.515

View
Cc1ccncc1NC(=O)C(=O)c1cccc(Cl)c1

MAK-UNK-6ca90168-24
0.507

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.507

View
Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

TRY-UNI-714a760b-18
0.507

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-4
0.507

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-5
0.507

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-4
0.507

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-5
0.507

View
Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)N(C)C

JAN-GHE-83b26c96-10
0.507

View
Cc1ccncc1NC(=O)N(c1cccc(Cl)c1)c1cccc(Cl)c1

EDG-MED-0da5ad92-19
0.500

View
Cc1ccncc1NC(=O)N(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-3
0.500

View
Cc1ccncc1NC(=O)C(CO)c1cccc(Cl)c1

EDG-MED-0da5ad92-5
0.500

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Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC1

JAN-GHE-83b26c96-20
0.493

View
Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC1

EDG-MED-0da5ad92-11
0.493

View
Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC(=O)C1

BAR-COM-0f94fc3d-25
0.474

View
Cc1ccncc1NC(=O)C(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-1
0.468

View
CCCC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

JAN-GHE-83b26c96-8
0.468

View
Cc1ccncc1NC(=N)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-6
0.465

View
Cc1ccncc1NC(=O)c1cncc(NC(=O)C(C)c2cccc(Cl)c2)c1C

MAK-UNK-f203cb68-22
0.459

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Cc1ccncc1NC(=O)N(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-2
0.455

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Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

TRY-UNI-9f475305-3
0.451

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Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-3
0.451

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Cc1ccncc1NC(=O)CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-3
0.450

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CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.448

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CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.448

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Cc1ccncc1NC(=O)Cc1cccc(C(C)(F)F)c1

DAR-DIA-0cde14eb-79
0.447

View
Cc1ccncc1NC(=O)C(C(=O)C(C)c1cccc(Cl)c1)c1cnccc1C

MAK-UNK-f203cb68-19
0.439

View
CC(=O)Nc1cnccc1CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-1
0.435

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Cc1nnc(N(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-4
0.434

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Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.429

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Cc1ccncc1NC(=O)CC(C)(C)c1ccccc1

BEN-DND-93268d01-13
0.425

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Cc1ccncc1NC(=O)C1(Cc2cccc(Cl)c2)CCOCC1

SAD-SAT-7d5528d9-4
0.424

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Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

DAR-DIA-0cde14eb-76
0.421

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Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

JAN-GHE-83b26c96-14
0.421

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
0.421

View
Cc1ccncc1NC(=O)N(Cc1ccccc1)c1cccc(Cl)c1

EDG-MED-0da5ad92-20
0.417

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Cc1ccncc1NS(=O)(=O)c1cccc(Cl)c1

JAN-GHE-83b26c96-21
0.417

View
Cc1ccncc1NC(=O)c1cc(C)c(NC(=O)C(C)c2cccc(Cl)c2)cn1

MAK-UNK-f203cb68-21
0.414

View
Cc1ccncc1NC(=O)Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-4
0.414

View
Cc1ccncc1NC(=O)N(CCC1CCCCC1)c1cccc(Cl)c1

MAT-POS-136e7878-1
0.414

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C=CC(=O)Nc1cnccc1C

MAK-UNK-6ca90168-27
0.413

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CCC(F)(F)c1cccc(CC(=O)Nc2cnccc2C)c1

DAR-DIA-0cde14eb-77
0.412

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Cc1ccncc1NC(=O)C1CCN(Cc2cccc(Cl)c2)CC1

SAD-SAT-7d5528d9-7
0.412

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.411

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.411

View
Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.409

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Cc1ccncc1NC(=O)[C@@H]1CC(=O)N(C)[C@@H]1c1cccc(Cl)c1

MAR-TRE-4b834d9a-26
0.402

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Cc1ccncc1NC(=O)c1nccc(C)c1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-20
0.400

View
Cc1ccncc1NC(=O)C(C)c1cncc(Cl)c1

TRY-UNI-2eddb1ff-3
0.400

View
COc1ccccc1OC[C@H](C(=O)Nc1cnccc1C)c1cccc(Cl)c1

ADA-UCB-6c2cb422-9
0.396

View
Cc1ccncc1NC(=O)CCc1nc2cc(Cl)ccc2o1

GAB-REV-70cc3ca5-22
0.395

View
Cc1ccncc1NC(=O)Cn1ccc2ccc(Cl)cc21

BAR-COM-0f94fc3d-41
0.395

View
Cc1ccncc1NS(=O)(=O)Cc1cccc(Cl)c1

JAN-GHE-83b26c96-17
0.395

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(C(N)=O)c1

RAL-THA-6b94ceba-6
0.392

View
CC(=O)N[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-13
0.391

View
Cc1ccncc1NC(=O)[C@@H]1CCc2ccc(Cl)cc21

ADA-UCB-6c2cb422-2
0.390

View
COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.390

View
Cc1ccncc1NC(=O)C(C)c1ccccc1

AHN-SAT-202241f6-1
0.389

View
Cc1ccncc1NC(=O)C(C)c1ccccc1

TRY-UNI-714a760b-17
0.389

View
Cc1ccncc1NC(=O)C1CCOc2ccc(Cl)cc21

JAN-GHE-f4ca5a00-13
0.388

View
Cc1ccncc1NC(=O)C1CCOc2ccc(Cl)cc21

BRU-CON-c4e3408a-1
0.388

View
CO[C@H](C)C(=O)Nc1cnccc1C

ERI-UCB-5b47150d-1
0.388

View
CO[C@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-1
0.388

View
CO[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-2
0.388

View
Cc1ccncc1NC(=O)Nc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-6
0.388

View
Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.387

View
Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.387

View
Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.387

View
Cc1ccncc1CC(=O)Nc1cccc(Cl)c1

EDJ-MED-49816e9b-1
0.387

View
Cc1ccncc1NC(=O)Nc1ccccc1

TRY-UNI-714a760b-4
0.386

View
Cc1ccncc1NC(=O)Nc1ccccc1

ALE-HEI-f28a35b5-1
0.386

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-11
0.386

View
COc1cc(Cl)cc(OC(=O)Nc2cnccc2C)c1

MAT-POS-6c3d76b3-1
0.385

View
COc1cc(Cl)cc(OC(=O)Nc2cnccc2C)c1

MAT-POS-0d6fb2dd-1
0.385

View
CC(=O)Nc1ccc(NCC(=O)Nc2cnccc2C)cc1

GAB-REV-70cc3ca5-21
0.384

View
Cc1ccncc1NC(=O)C(F)c1ccccc1

ABI-SAT-4d06482b-1
0.384

View
Cc1ccncc1NC(=O)Cc1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-2
0.383

View
CNC(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-7
0.383

View
Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.382

View
Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.382

View
Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.380

View
COc1cccc(C(O)C(=O)Nc2cnccc2C)c1

BAR-COM-0f94fc3d-19
0.380

View
Cc1ccncc1NC(=O)C(CO)c1ccccc1

BEN-DND-93268d01-3
0.378

View
Cc1ccncc1NC(=O)Cc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-3
0.378

View
CC(C(=O)Nc1cnccc1C)=C1CC1

ERI-UCB-5b47150d-4
0.377

View
COc1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

MAT-POS-c9973a83-1
0.375

View
Cc1ccncc1NC(=O)Nc1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-5
0.375

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-10
0.373

View
Cc1ccncc1NC(=O)c1ccc(Cl)cc1C(C)C(=O)Nc1cnccc1C

MAK-UNK-f203cb68-15
0.373

View
CNS(=O)(=O)c1cc(Cl)cc(CC(=O)Nc2cnccc2C)c1

RAL-THA-6b94ceba-14
0.373

View
Cc1ccncc1NC(=O)Cc1ccccc1N

ANN-UNI-98d2bf15-1
0.373

View
Cc1ccncc1NC(=O)Nc1cccc(C#N)c1

TRY-UNI-714a760b-24
0.372

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

1.000

View
CC1=CN=CC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.683

View
CC(C)(C(=O)NC1=CN=CC=C1O)C1=CC=CC(Cl)=C1

0.683

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC(Br)=C1

0.683

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC(F)=C1

0.683

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC(C(F)(F)F)=C1

0.672

View
CC1=CC=NC=C1NC(=O)C(F)(F)C1=CC=CC(Cl)=C1

0.662

View
COC1=CC=CC(C(C)(C)C(=O)NC2=CN=CC=C2C)=C1

0.662

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(Cl)C(Cl)=C1

0.661

View
CC1=CN=NC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.651

View
COC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.642

View
CC(C)(C(=O)NC1=CC=NC=C1Br)C1=CC=CC(Cl)=C1

0.641

View
CCC(O)(C(=O)NC1=CN=CC=C1C)C1=CC=CC(Cl)=C1

0.632

View
CC1=CC(Cl)=NC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.631

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(Cl)C=C1

0.629

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC=C1

0.623

View
CC(C)(C(=O)NC1=CC=NC=C1F)C1=CC=CC(Cl)=C1

0.621

View
CC(C)(C(=O)NC1=CC=NC=C1I)C1=CC=CC(Cl)=C1

0.621

View
CC1=CC(Br)=NC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.621

View
CC(C)(C(=O)NC1=CN=CC(Cl)=C1Cl)C1=CC=CC(Cl)=C1

0.615

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(F)C(F)=C1

0.615

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CN=C1

0.613

View
CCC1=CN=CC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.612

View
CC(C)(C(=O)NC1=CC=CC2=CC=NC=C12)C1=CC=CC(Cl)=C1

0.606

View
CC1=CC=CC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.603

View
CC1=CC(C(C)(C)C(=O)NC2=CN=CC=C2C)=CC=C1Br

0.600

View
CC1=NC=NC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.597

View
CC1=CC=NC=C1NC(=O)NC(C)(C)C1=CC=CC(Cl)=C1

0.594

View
CC1=CC(C(F)(F)F)=NC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.594

View
CC1=CSC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.594

View
CC(=O)NC1=CC=C(C)C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C1

0.588

View
CC1=CC=NC=C1S(=O)(=O)NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.586

View
CC1=CC=CC(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C1C

0.585

View
CC1=NN=CC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.582

View
COC1=CC=C(C(C)(C)C(=O)NC2=CN=CC=C2C)C=C1OC

0.582

View
CC1=CC=C(C(=O)O)C=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.582

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(C(C)(C)C)C=C1

0.581

View
CC1=CC=NC=C1NC(=O)C(C)(C)OC1=CC=CC(Cl)=C1

0.580

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C2C=CC=CC2=C1

0.580

View
CC(C)(C(=O)NC1=CC=NC=C1)C1=CC=CC(Cl)=C1

0.578

View
CC1=CC=C(C)C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C1

0.576

View
CC(C)(C(=O)NC1=CC=CN=C1)C1=CC=CC(Cl)=C1

0.576

View
CC(C)(C(=O)NC1=CN=CC=N1)C1=CC=CC(Cl)=C1

0.576

View
CC(C)(C(=O)NC1=CC=NC2=CC=NC=C12)C1=CC=CC(Cl)=C1

0.575

View
CC1=CC(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C(C)C=N1

0.574

View
CC1=CC=NC=C1NC(=O)C(C)(C)CC1=CC=CC(Cl)=C1

0.571

View
CC1=CC=NC=C1CNC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.571

View
CC1=CC=C(C(C)(C)C(=O)NC2=CN=CC=C2C)C=C1

0.571

View
CC1=NC=CC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.567

View
CC1=C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)C=NN1C

0.567

View
CC1=CC(Cl)=CN=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.567

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(Cl)C=C1F

0.565

View
CC1=CC=NC=C1C(C)NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.563

View
CC1=CC=NC=C1NC(=O)NCC(C)(C)C1=CC=CC(Cl)=C1

0.562

View
CC1=CC=NC=C1NC(=O)NCC(C)(O)C1=CC=CC(Cl)=C1

0.562

View
CC1=CC(O)=CC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.561

View
CC1=CC=C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)C(C)=C1

0.561

View
CC1=CC=C(F)C=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.559

View
CC1=CC=NC=C1CCNC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.556

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(Br)C=C1

0.554

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(F)C=C1

0.554

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(C(F)(F)F)C=C1

0.554

View
CC(C)(C(=O)NC1=CC=CN=C1Cl)C1=CC=CC(Cl)=C1

0.552

View
CC1=CC=CC(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C1F

0.552

View
CC1=CC=CC(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C1O

0.552

View
CC1=NC(Cl)=CC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.552

View
CC1=CN=C(Cl)C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C1

0.551

View
CC1=NC=C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)C(C)=N1

0.551

View
CC1=NC=CC(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C1Cl

0.551

View
CC(C)(C(=O)NC1=CC=CC=C1Cl)C1=CC=CC(Cl)=C1

0.547

View
CC1=CC=NC=C1NC(=O)C(=O)NCC(C)(C)C1=CC=CC(Cl)=C1

0.547

View
CC1=CC=NC=C1NC(=O)C(=O)NCC(C)(O)C1=CC=CC(Cl)=C1

0.547

View
CC(C)(C(=O)NC1=CN=CN=C1)C1=CC=CC(Cl)=C1

0.545

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC=C1Cl

0.544

View
CC1=CC=CN=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.544

View
CC1=CC=C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)C(Cl)=N1

0.544

View
CC1=CC(F)=CC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.544

View
CC1=CC=C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)C(C)=N1

0.544

View
CC1=CC=C(C(N)=O)C=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.543

View
CC1=NC=C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)C=N1

0.537

View
CC1=CN=CC(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=C1

0.536

View
CC1=C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)N(C)N=C1

0.536

View
CC1=CC=NC=C1NC(=O)C1=CC=CC(Cl)=C1

0.530

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C(C2=CC=CC=C2)C=C1

0.529

View
CC(C)(C(=O)NNC1=CC=NC=C1Cl)C1=CC=CC(Cl)=C1

0.529

View
CC1=CN=CC=C1CNC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.528

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C2OCCOC2=C1

0.527

View
CCOC1=CC=C(C(C)(C)C(=O)NC2=CN=CC=C2C)C=C1OCC

0.527

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=C2OCOC2=C1

0.527

View
CC1=CC=C(C(=O)N(C)C)C=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.521

View
CC1=NC=C(C)C(NC(=O)C(C)(C)C2=CC=CC(Cl)=C2)=N1

0.514

View
CC(C)(C(=O)NC1=NC=CC2=CC=NC=C12)C1=CC=CC(Cl)=C1

0.506

View
CC1=CC=C(C2=CC=NN2C)C=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.506

View
CC1=CC=NC=C1NC(=O)C(=O)NCC1=CC=CC(Cl)=C1

0.467

View
CC1=CC=NC=C1NC(=O)C(=O)NNC1=CC=CC(Cl)=C1

0.467

View
CC1=CN=CC=C1NC(=O)C(F)(F)C1=CC=CC(Cl)=C1

0.459

View
CC1=CC(Cl)=CC=C1NC(=O)C(C)(C)C1=CC=CN=C1

0.458

View
CC1=CC=C(Cl)C=C1NC(=O)C(C)(C)C1=CC=CN=C1

0.452

View
CC1=CN=CC=C1NC(=O)C(C)(C)C1=CC=CC(Br)=C1

0.452

View
CC1=CN=CC=C1NC(=O)C(C)(C)C1=CC=CC(C(F)(F)F)=C1

0.452

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

0.507

View
CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

0.507

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)cc1

0.408

View
CC(C(=O)Nc1cnccc1C)c1ccccc1

0.389

View
Cc1ccncc1NC(=O)Cc1ccccc1

0.380

View
CC(C(=O)Nc1cccnc1)c1ccc(Cl)cc1

0.222

View
Clc1ccc(CC(=O)Nc2cccnc2)cc1Cl

0.205

View
C(NC1=C(C)C=CN=C1)(=O)C(C)C1=CC=C(Cl)C=C1

0.855

View
C(NC1=C(C)C=CN=C1)(=O)C(C)C1=CC=CC=C1

0.814

View
C(NC1=CN=CC(Cl)=C1C)(=O)C(C)C1=CC=C(Cl)C=C1

0.798

View
C(NC1=C(C)C=CN=C1)(=O)C(C1=CC=C(C)C=C1)C

0.790

View
C(NC1=C(C)C=CN=C1)(=O)CC1=CC=CC(Cl)=C1

0.786

View


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