Molecule Details

Cc1ccncc1NC(=O)Nc1cccc(Cl)c1
3-aminopyridine-like Enamine MolPort Assayed
View on Fragalysis x2908
Molecular Properties
SMILES:
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1
MW: 261.712
Fraction sp3: 0.08
HBA: 2
HBD: 2
Rotatable Bonds: 2
TPSA: 54.02
cLogP: 3.68742
Covalent Warhead:
Covalent Fragment: ✔️
Source
Enamine SCR: Z1130395540
MolPort: MolPort-047-314-818
Activity Data
IC50 (µM) - Fluorescence: 64.4136105144302
IC50 (µM) - RapidFire: 45.6892627861479
Trypsin IC50 (µM): 99.0
pIC50 (µM) - Fluorescence 4.19102235706909
Average Inhibition @ 20 µM - Fluorescence: 32.14497
Average Inhibition @ 50 µM - Fluorescence: 58.708675
Average Inhibition @ 20 µM - RapidFire: 25.5825
Average Inhibition @ 50 µM - RapidFire: 64.135
Relative Solubility @ 20 µM: 0.99
Relative Solubility @ 100 µM: 0.96
Order Status
Ordered: 2020-03-31
Synthesis Location: enamine
Shipped: 2020-04-17
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

JAG-UCB-cedd89ab-8
1.000

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Cc1ccncc1NC(=O)Nc1cccc(C#N)c1

TRY-UNI-714a760b-24
0.625

View
Cc1ccncc1NC(=O)Nc1ccccc1

ALE-HEI-f28a35b5-1
0.621

View
Cc1ccncc1NC(=O)Nc1ccccc1

TRY-UNI-714a760b-4
0.621

View
Cc1ccncc1NC(=O)Nc1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-6
0.612

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Cc1ccncc1NC(=O)Nc1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-5
0.597

View
Cc1ccncc1NC(=O)Nc1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-7
0.588

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Cc1ccncc1NC(=O)Nc1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-8
0.588

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Cc1c(N)cncc1NC(=O)Nc1cccc(Cl)c1

TRY-UNI-714a760b-9
0.585

View
Cc1ccncc1NC(=O)Nc1cccc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-9
0.571

View
O=C(Nc1cccnc1)Nc1cccc(Cl)c1

DAR-DIA-23aa0b97-14
0.567

View
O=C(Nc1cccnc1)Nc1cccc(Cl)c1

WAR-XCH-eb7b662f-7
0.567

View
O=C(Nc1cccnc1)Nc1cccc(Cl)c1

JOR-UNI-2fc98d0b-7
0.567

View
O=C(Nc1cccnc1)Nc1cccc(Cl)c1

JAN-GHE-83b26c96-19
0.567

View
Cc1ccncc1NC(=O)N(c1cccc(Cl)c1)c1cccc(Cl)c1

EDG-MED-0da5ad92-19
0.545

View
Cc1ccncc1NC(=O)C(CO)c1cccc(Cl)c1

EDG-MED-0da5ad92-5
0.544

View
Cc1ccncc1NC(=O)C(C)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-18
0.537

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Cc1ccncc1CC(=O)Nc1cccc(Cl)c1

EDJ-MED-49816e9b-1
0.530

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Cc1ccncc1NC(=O)C(=O)c1cccc(Cl)c1

MAK-UNK-6ca90168-24
0.530

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.530

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-5
0.529

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-4
0.529

View
Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

TRY-UNI-714a760b-18
0.529

View
Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-4
0.529

View
Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-5
0.529

View
Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)N(C)C

JAN-GHE-83b26c96-10
0.529

View
Cc1ccncc1NC(=O)N(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-3
0.522

View
Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)C(C)C

JAN-GHE-83b26c96-9
0.522

View
Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1

JAN-GHE-83b26c96-22
0.515

View
Cc1ccncc1NC(=O)C(C)(C)c1cccc(Cl)c1

EDG-MED-0da5ad92-10
0.515

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Cc1ccncc1NC(=O)Nc1cncc(C#N)c1

CHR-SOS-363cfb78-2
0.515

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CCCC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

JAN-GHE-83b26c96-8
0.507

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Cc1ccncc1NC(=O)C(F)(F)c1cccc(Cl)c1

JAN-GHE-83b26c96-23
0.500

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Cc1ccncc1NC(=O)N(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-2
0.493

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Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC1

JAN-GHE-83b26c96-20
0.493

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Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC1

EDG-MED-0da5ad92-11
0.493

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Nc1cncc(NC(=O)Nc2cccc(Cl)c2)c1

DAR-DIA-23aa0b97-13
0.492

View
Cc1ccncc1NC(=O)CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-3
0.487

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Cc1ccncc1NC(=O)C(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-1
0.486

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Cc1ccncc1NC(=O)c1cccc(NC(=O)Nc2cccnc2)c1

MAK-UNK-129dcd6f-9
0.486

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Cc1ccncc1NC(=O)Nc1cnn(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-66
0.486

View
Cc1ccncc1NC(=N)Cc1cccc(Cl)c1

EDG-MED-0da5ad92-6
0.485

View
CCC(O)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

BAR-COM-0f94fc3d-38
0.479

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Cc1ccncc1NC(=O)C1(c2cccc(Cl)c2)CC(=O)C1

BAR-COM-0f94fc3d-25
0.473

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CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.473

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CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.473

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Cc1ccncc1NC(=O)Nc1cnn(C2(I)CC2)c1

DAR-DIA-0cde14eb-68
0.472

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Cc1ccncc1NC(=O)Nc1cnn(C2(C)CC2)c1

DAR-DIA-0cde14eb-65
0.472

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Cc1nnc(NC(=O)Nc2cnccc2C)s1

ALE-HEI-f28a35b5-2
0.470

View
Cc1ccncc1NC(=O)Nc1cnn(C2(F)CC2)c1

DAR-DIA-0cde14eb-67
0.466

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O=C(Nc1cccc(Cl)c1)Nc1cnccc1CCNC(=O)NC1CCCCC1

DAR-DIA-03336633-3
0.460

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Cc1ccncc1NC(=O)c1ccncc1NC(=O)Nc1ccccc1

MAK-UNK-129dcd6f-15
0.459

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Cc1ccncc1NS(=O)(=O)c1cccc(Cl)c1

JAN-GHE-83b26c96-21
0.456

View
Cc1ccncc1NC(=O)C(C(=O)C(C)c1cccc(Cl)c1)c1cnccc1C

MAK-UNK-f203cb68-19
0.456

View
Cc1ccncc1NC(=O)Nc1cnn(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-69
0.453

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Cc1ccncc1NC(=O)NCCBr

ALE-HEI-f28a35b5-13
0.453

View
CC(=O)Nc1cnccc1CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-1
0.451

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Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-3
0.450

View
Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

TRY-UNI-9f475305-3
0.450

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Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.450

View
Cc1nnc(N(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-4
0.450

View
CC(=O)Nc1cnccc1C(C)(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-9
0.450

View
Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.443

View
COc1ccccc1OC[C@H](C(=O)Nc1cnccc1C)c1cccc(Cl)c1

ADA-UCB-6c2cb422-9
0.442

View
Cc1ccncc1NC(=O)c1ccc(Cl)cc1C(C)C(=O)Nc1cnccc1C

MAK-UNK-f203cb68-15
0.442

View
Cc1ccncc1NC(=O)c1cncc(NC(=O)C(C)c2cccc(Cl)c2)c1C

MAK-UNK-f203cb68-22
0.440

View
Cc1ccncc1NC(=O)Nc1cc(N2CCCCC2)cc(C2(C)CC2)c1

DAR-DIA-0cde14eb-20
0.439

View
Cc1ccncc1NC(=O)C(C)c1cncc(Cl)c1

TRY-UNI-2eddb1ff-3
0.437

View
Cc1ccncc1NC(=O)c1ccccc1NC(=O)Nc1cccnc1

MAK-UNK-129dcd6f-4
0.436

View
CCNc1ncc(C#N)cc1NC(=O)Nc1cnccc1C

TRY-UNI-1fd04853-2
0.434

View
Cc1ccncc1NC(=O)c1ccc(NC(=O)Nc2ccccc2)cn1

MAK-UNK-129dcd6f-17
0.434

View
C=CC(=O)Nc1cnccc1C

MAK-UNK-6ca90168-27
0.433

View
Cc1ccncc1NC(=O)N(Cc1ccccc1)c1cccc(Cl)c1

EDG-MED-0da5ad92-20
0.432

View
Cc1ccncc1NC(=O)c1ncccc1NC(=O)Nc1ccccc1

MAK-UNK-129dcd6f-18
0.430

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

TRY-UNI-2eddb1ff-2
0.429

View
Cc1ccncc1NC(=O)Cc1cncc(Cl)c1

EDG-MED-0da5ad92-8
0.429

View
CO[C@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-1
0.429

View
CO[C@H](C)C(=O)Nc1cnccc1C

ERI-UCB-5b47150d-1
0.429

View
Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.429

View
CO[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-2
0.429

View
Cc1ccncc1NC(=O)Nc1cc(N2CCCCC2)cc(C2(F)CC2)c1

DAR-DIA-0cde14eb-22
0.429

View
Cc1ccncc1NC(=O)c1cc(C)c(NC(=O)C(C)c2cccc(Cl)c2)cn1

MAK-UNK-f203cb68-21
0.429

View
Cc1ccncc1NC(=O)Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

MAK-UNK-f203cb68-4
0.429

View
Cc1ccncc1NC(=O)C1CCN(Cc2cccc(Cl)c2)CC1

SAD-SAT-7d5528d9-7
0.427

View
O=C(Nc1cccc(Cl)c1)Nc1nccc2[nH]ncc12

JAG-UCB-cedd89ab-7
0.427

View
Cc1ccncc1NC(=O)NC1CCCCC1

TRY-UNI-714a760b-11
0.426

View
Cc1ccncc1NC(=O)C(C)c1ccccc1

TRY-UNI-714a760b-17
0.426

View
Cc1ccncc1NC(=O)NC1CCCCC1

ALE-HEI-f28a35b5-7
0.426

View
Cc1ccncc1NC(=O)C(C)c1ccccc1

AHN-SAT-202241f6-1
0.426

View
Cc1ccncc1NC(=O)Nc1cc(N2CCCCC2)cc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-21
0.424

View
Cc1ccncc1NC(=O)c1cncc(NC(=O)Nc2ccccc2)c1

MAK-UNK-129dcd6f-16
0.423

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(C)(=O)=O)c1

WIL-MOD-03b86a88-5
0.423

View
Cc1ccncc1NC(=O)C1(Cc2cccc(Cl)c2)CCOCC1

SAD-SAT-7d5528d9-4
0.422

View
Cc1ccncc1NC(=O)Nc1ccccc1CCNS(C)(=O)=O

SIM-DEM-f31d0e65-1
0.421

View
O=C(O)CCCc1cncc(NC(=O)Nc2cccc(Cl)c2)c1

JAN-LUN-8953ce76-6
0.421

View
Cc1ccncc1NC(=O)c1ccc(NC(=O)Nc2cccnc2)cc1

MAK-UNK-129dcd6f-12
0.421

View
O=C(O)CCCc1cncc(NC(=O)Nc2cccc(Cl)c2)c1

JAN-LUN-3e0f9c09-1
0.421

View
CC(=O)Nc1ccc(NCC(=O)Nc2cnccc2C)cc1

GAB-REV-70cc3ca5-21
0.420

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(NS(N)(=O)=O)c1

WIL-MOD-03b86a88-6
0.418

View
O=C(Nc1cccc(Cl)c1)[C@@]1(c2cccnc2)CO1

BEN-DND-61647d40-19
0.417

View
CC(=O)NC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.690

View
CC1=CC=NC=C1NC(=O)CNC(=O)NC1=CC=CC(Cl)=C1

0.677

View
CC1=CC=NC=C1NC(=O)NNC1=CC=CC(Cl)=C1

0.667

View
COC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.645

View
COC(=O)NC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.645

View
CC1=CC=NC=C1NC(=S)NC1=CC=CC(Cl)=C1

0.639

View
COC1=CC=NC=C1NC(=O)NC1=CC=CC(Cl)=C1

0.635

View
CSC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.635

View
CCC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.635

View
CC1=CC=NC=C1NC(=O)NC1=CC=CC(C(C)(C)O)=C1

0.635

View
CCSC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.621

View
CC1=CSC=C1NC(=O)NC1=CC=CC(Cl)=C1

0.617

View
CC1=CC=NC=C1NC(=O)NC1=CC(OC(C)C)=CC=C1

0.615

View
CCOC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.606

View
CC1=CC=NC=C1NC(=O)NC1=CC=CC(OC(F)F)=C1

0.606

View
COC(C)C(=O)NC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.606

View
CC1=CC=NC=C1NC(=O)NC1=CC=C(O)C(Cl)=C1

0.603

View
CC1=CC=NC=C1NC(=O)CNC1=CC=CC(Cl)=C1

0.600

View
CC1=CC=CC=C1NC(=O)NC1=CC=CC(Cl)=C1

0.600

View
COCC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.597

View
CC1=CC=NC=C1NC(=O)NC1=CC=CC(CC(F)(F)F)=C1

0.597

View
CCC(C)OC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.594

View
CC1=CC=NC=C1NC(=O)NC1=CSC(Cl)=C1

0.587

View
CC1=CC(C)=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.583

View
CC1=CC=NC=C1NC(=O)NC1=CC(C)=C(O)C(C)=C1

0.583

View
CC1=CC=NC=C1NC(=O)NCC1=CC=CC(Cl)=C1

0.582

View
CC1=CC(NC(=O)NC2=CN=CC=C2C)=CC=C1O

0.581

View
CC1=CC=NC=C1NC(=O)NC1=CC=CC(N2C=CN=N2)=C1

0.580

View
COC(=O)CC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.580

View
CC1=CC=NC=C1NC(=O)N(C)CC(=O)NC1=CC=CC(Cl)=C1

0.577

View
CC(=O)NC1=CC=C(NC(=O)NC2=CN=CC=C2C)C=C1

0.576

View
CC1=CC=NC=C1NC(=O)C(=O)NNC1=CC=CC(Cl)=C1

0.574

View
CC1=CC=NC=C1NC(=O)NC(C)C1=CC=CC(Cl)=C1

0.574

View
CC1=CC=C(C)C(NC(=O)NC2=CC=CC(Cl)=C2)=C1

0.571

View
CC(=O)NC1=CC(NC(=O)NC2=CN=CC=C2C)=CC=C1C

0.571

View
CC1=C(NC(=O)NC2=CC=CC(Cl)=C2)C=NO1

0.571

View
CC(=O)NC1=CC=C(NC(=O)NC2=CN=CC=C2C)C=C1C

0.571

View
COCCOC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.571

View
O=C(NC1=CC=CN=C1)NC1=CC(Cl)=CC=C1

0.567

View
CC1=CC=C(NC(=O)NC2=CN=CC=C2C)C=C1

0.567

View
CC1=CC=NC=C1NC(=O)NCCC1=CC=CC(Cl)=C1

0.565

View
CC1=CC=NC=C1NC(=O)NC1=CC=CC(NC2CCCC2)=C1

0.563

View
CC1=CC=NC=C1NC(=O)NC1=CC(COC(C)C)=CC=C1

0.563

View
CNC(=O)COC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.563

View
CCOC(=O)CC1=CC=CC(NC(=O)NC2=CN=CC=C2C)=C1

0.563

View
CC1=C(NC(=O)NC2=CC=CC(Cl)=C2)C=NN1C

0.562

View
CN1CCN(C2=CC=NC=C2NC(=O)NC2=CC=CC(Cl)=C2)CC1

0.562

View
CC1=CC=NC=C1NC(=O)C(=O)N(C)CC(=O)NC1=CC=CC(Cl)=C1

0.562

View
CC1=CC=NC=C1NC(=O)NNC(=O)C1=CC=CC(Cl)=C1

0.559

View
CC1=CC=NC=C1NC(=O)NC1=CC=C(O)C=C1

0.557

View
CC1=CC=NC=C1NC(=O)C1=CC=CC(Cl)=C1

0.556

View
CC1=CC=CC(NC(=O)NC2=CC=CC(Cl)=C2)=C1C

0.556

View
CC1=CC=NC=C1NC(=O)NC1=CC(C2=NN=C(C)N2C)=CC=C1

0.556

View
CC1=CC=C(NC(=O)NC2=CC=CC(Cl)=C2)C(C)=C1

0.556

View
CC1=CC=NC=C1NC(=O)NC(C)(C)C1=CC=CC(Cl)=C1

0.551

View
CC1=CC=NC=C1NC(=O)NC1(C2=CC=CC(Cl)=C2)CC1

0.551

View
CC1=CC=C(NC(=O)NC2=CC=CC(Cl)=C2)C=C1C

0.550

View
CC1=CC(O)=CC=C1NC(=O)NC1=CC=CC(Cl)=C1

0.547

View
CC(=O)NC1=CC(NC(=O)NC2=CC=CC(Cl)=C2)=CC=C1C

0.547

View
CC1=CC=NC=C1C(C)NC(=O)NC1=CC=CC(Cl)=C1

0.544

View
CC1=CC=NC=C1NC(=O)CCC1=CC=CC(Cl)=C1

0.544

View
CC1=CC=NC=C1NC(=O)NC(CO)C1=CC=CC(Cl)=C1

0.543

View
CC1=CC=NC=C1NC(=O)NCCCC1=CC=CC(Cl)=C1

0.542

View
CC1=CC=NC=C1NC(=O)NCC(C)(C)C1=CC=CC(Cl)=C1

0.542

View
CC1=CN=CC(NC(=O)NC2=CC=CC(Cl)=C2)=C1

0.540

View
CCC(NC(=O)NC1=CN=CC=C1C)C1=CC=CC(Cl)=C1

0.535

View
CC1=CC=CC=C1NC(=O)NC1=CN=CC=C1C

0.533

View
CC1=CC=NC=C1C(=O)NC1=CC=CC(Cl)=C1

0.531

View
CC1=CC=NC=C1NC(=O)NNC1=CC(Cl)=CC(Cl)=C1

0.530

View
CC1=CC=NC=C1NC(=O)CC1=CC=CC(Cl)=C1

0.530

View
CC1=CC=NC=C1NC(=O)C(C)C1=CC=CC(Cl)=C1

0.529

View
CC1=CC=NC=C1NC(=O)NCC(O)C1=CC=CC(Cl)=C1

0.528

View
CC1=CC=NC=C1NC(=O)NC1=C(C)C(C)=CC=C1

0.524

View
CCOC1=CC(NC(=O)NC2=CN=CC=C2C)=CC=C1C

0.522

View
CC1=CC=C(NC(=O)NC2=CC=CC(Cl)=C2)C=C1NC(=O)C1=CC=NC=C1

0.521

View
CC1=CC=CC=C1NC(=O)NNC(=O)NC1=CC=CC(Cl)=C1

0.515

View
CC1=CC=NC=C1NC(=O)C(C)(C)C1=CC=CC(Cl)=C1

0.515

View
CC1=CC=NC=C1NC(=O)NC(C1=CC=CC=C1)C1=CC=CC(Cl)=C1

0.514

View
CC1=CC=NC=C1NC(=O)NCCOC1=CC=CC(Cl)=C1

0.514

View
CC1=CN=CC=C1C(=O)NC1=CC=CC(Cl)=C1

0.508

View
CC1=CC=NC=C1NC(=O)NC1(CC2=CC=CC(Cl)=C2)CC1

0.507

View
CC1=CC=CC(NC(=O)NC2=CC=CC(CNC(=O)NC3=CN=CC=C3C)=C2)=C1

0.506

View
CC1=CC=NC=C1NC(=O)C(=O)N1CCCN(C(=O)NC2=CC=CC(Cl)=C2)CC1

0.506

View
CC1=CC=NC=C1NC(=O)C(F)(F)C1=CC=CC(Cl)=C1

0.500

View
CC1=CN=CC=C1CNC(=O)NC1=CC=CC(Cl)=C1

0.500

View
CC1=CC=C(C2=CC=NN2C)C=C1NC(=O)NC1=CC=CC(Cl)=C1

0.500

View
CC(=O)NC1=CC=CC(CNC(=O)NC2=CN=CC=C2C)=C1

0.500

View
CC1=CC=NC=C1NC(=O)C(C)(C)OC1=CC=CC(Cl)=C1

0.493

View
CC1=CC=NC=C1CNC(=O)CNC(=O)NC1=CC=CC(Cl)=C1

0.487

View
CC1=CC=NC=C1NC(=O)C(C)(C)CC1=CC=CC(Cl)=C1

0.486

View
CC1=CC=NC=C1NC(=O)C(=O)NCC1=CC=CC(Cl)=C1

0.486

View
CC1=CC=CC(NC(=O)C(=O)NC2=CN=CC=C2C)=C1

0.485

View
CC1=CN=CC=C1CCNC(=O)NC1=CC=CC(Cl)=C1

0.479

View
CC1=CN=CC=C1NC(=O)NNC1=CC=CC(Cl)=C1

0.479

View
O=C(NNC1=CC=NC=C1Cl)NC1=CC(Cl)=CC=C1

0.478

View
CC1=CC=NC=C1NC(=O)NCC1=CC=CC(NC(=O)NCC2=CC=NC=C2)=C1

0.474

View
CC1=CC=NC=C1C(=O)NC1=CC=CC=C1C(=O)NC1=CC=CC(Cl)=C1

0.468

View
CC1=CC=NC=C1NC(=O)C1=CC=C(Cl)C=C1Cl

0.456

View
CC1=CC=C(Cl)C=C1NC(=O)NC1=CC=CN=C1

0.443

View
CC1=CC=C(Cl)C=C1NC(=O)NC1=CC=CC(O)=C1

0.429

View
Cc1ccncc1NC(=O)Nc1cccc(Cl)c1

1.000

View
Cc1ccncc1NC(=O)Nc1ccccc1

0.621

View
Clc1cccc(NC(=O)Nc2cccnc2)c1

0.567

View
Cc1ccc(Cl)cc1NC(=O)Nc1cccnc1

0.443

View
FC(F)(F)c1ccncc1NC(=O)Nc1cc(Cl)cc(Cl)c1

0.389

View
Cc1c(Cl)cccc1NC(=O)Nc1cccnc1

0.375

View
Clc1cc(Cl)cc(NC(=O)Nc2cccnc2)c1

0.353

View
Clc1ccc(NC(=O)Nc2cccnc2)cc1Cl

0.343

View


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