Molecule Details

COCC(C(=O)Nc1cnccc1C)c1ccccc1
3-aminopyridine-like
Molecular Properties
SMILES:
COCC(C(=O)Nc1cnccc1C)c1ccccc1
MW: 270.14
Fraction sp3: 0.25
HBA: 3
HBD: 1
Rotatable Bonds: 5
TPSA: 51.22
cLogP: 2.76
Covalent Warhead:
Covalent Fragment:
CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

View

Cc1ccncc1NC(=O)C(CO)c1ccccc1

BEN-DND-93268d01-3
0.729

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Cc1ccncc1NC(=O)[C@H](CNS(C)(=O)=O)c1ccccc1

DAN-RED-da448e80-1
0.657

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Cc1ccncc1NC(=O)C(CNS(C)(=O)=O)c1ccccc1

DRE-WAB-eb790b7a-1
0.657

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Cc1ccncc1NC(=O)[C@@H](CNS(C)(=O)=O)c1ccccc1

PED-UNI-5b7f1100-1
0.657

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Cc1ccncc1NC(=O)[C@@H](CNS(C)(=O)=O)c1ccccc1

PED-UNI-8d53fd73-1
0.657

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Cc1ccncc1NC(=O)C(C)c1ccccc1

TRY-UNI-714a760b-17
0.587

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Cc1ccncc1NC(=O)C(C)c1ccccc1

AHN-SAT-202241f6-1
0.587

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Cc1ccncc1NC(=O)C(F)c1ccccc1

ABI-SAT-4d06482b-1
0.578

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Cc1ccncc1NC(=O)C(CN1CCC(O)CC1)c1ccccc1

SAM-UNK-2684b532-10
0.573

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Cc1ccncc1NC(=O)C(C)Cc1ccccc1

BEN-DND-93268d01-14
0.552

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CO[C@H](C)C(=O)Nc1cnccc1C

ERI-UCB-5b47150d-1
0.550

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CO[C@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-1
0.550

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CO[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-2
0.550

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Cc1ccncc1NC(=O)C(CO)c1cccc(Cl)c1

EDG-MED-0da5ad92-5
0.521

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COc1ccc([C@@H](CNS(C)(=O)=O)C(=O)Nc2cnccc2C)cc1

DAN-RED-da448e80-13
0.513

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COc1ccccc1OC[C@H](C(=O)Nc1cnccc1C)c1cccc(Cl)c1

ADA-UCB-6c2cb422-9
0.512

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Cc1ccncc1NC(=O)C(c1ccccc1)c1cccc(Cl)c1

SAM-UNK-2684b532-1
0.507

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CCCC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

JAN-GHE-83b26c96-8
0.487

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Cc1ccncc1NC(=O)[C@H](CNS(C)(=O)=O)c1ccc(Cl)cc1

DAN-RED-da448e80-9
0.487

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Cc1ccncc1NC(=O)[C@H](CNS(C)(=O)=O)c1ccc(F)cc1

DAN-RED-da448e80-5
0.487

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Cc1ccncc1NC(=O)Cc1ccccc1

TRY-UNI-714a760b-5
0.485

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CC(=O)N[C@@H](C)C(=O)Nc1cnccc1C

MAT-POS-590ac91e-13
0.477

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Cc1ccncc1NC(=O)[C@H](CNS(C)(=O)=O)c1cccs1

DAN-RED-da448e80-17
0.474

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COc1cccc(C(O)C(=O)Nc2cnccc2C)c1

BAR-COM-0f94fc3d-19
0.473

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Cc1ccncc1NC(=O)[C@H](C)OC(F)F

MAT-POS-590ac91e-16
0.470

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Cc1ccncc1NC(=O)[C@@H](C)OC(F)F

MAT-POS-5d20d11c-1
0.470

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Cc1ccncc1NC(=O)Nc1ccccc1

TRY-UNI-714a760b-4
0.470

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Cc1ccncc1NC(=O)Nc1ccccc1

ALE-HEI-f28a35b5-1
0.470

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Cc1ccncc1NC(=O)CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-3
0.468

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Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-4
0.466

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Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-4
0.466

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Cc1ccncc1NC(=O)[C@@H](C)c1cccc(Cl)c1

JAN-GHE-83b26c96-5
0.466

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Cc1ccncc1NC(=O)C(C)c1cccc(Cl)c1

TRY-UNI-714a760b-18
0.466

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Cc1ccncc1NC(=O)[C@H](C)c1cccc(Cl)c1

TRY-UNI-2eddb1ff-5
0.466

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COC(=O)C(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAT-POS-1e5f28a7-1
0.461

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Cc1ccncc1NC(=O)C(C)CC1CC1

MAT-POS-590ac91e-5
0.449

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CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8
0.448

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CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
0.448

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Cc1ccncc1NC(=O)CC(C)(C)c1ccccc1

BEN-DND-93268d01-13
0.444

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Cc1ccncc1NC(=O)CC(CNS(C)(=O)=O)c1ccccc1

WIL-WAB-6ef46ddb-1
0.443

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Cc1ccncc1NC(=O)CC(CNS(C)(=O)=O)c1ccccc1

PET-SGC-d5b502b1-1
0.443

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Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)C(C)C

JAN-GHE-83b26c96-9
0.440

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Cc1ccncc1NC(=O)C[C@H](c1ccccc1)N1CCC(O)CC1

ALP-POS-90c18d1d-1
0.439

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Cc1ccncc1NC(=O)C(CCc1ccccc1)c1cc(Cl)cc(OC2CC(=O)N2)c1

ALP-POS-3fc1724e-6
0.438

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CC(=O)Nc1cnccc1CC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

MAK-UNK-f203cb68-1
0.435

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Cc1ccncc1NC(=O)NCCBr

ALE-HEI-f28a35b5-13
0.433

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Cc1ccncc1NC(=O)CC#N

ASH-SAT-43770c7d-9
0.431

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Cc1ccncc1NC(=O)C(c1cccc(Cl)c1)N(C)C

JAN-GHE-83b26c96-10
0.429

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Cc1ccncc1NC(=O)CCl

MAK-UNK-6ca90168-26
0.429

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COc1cccc(CC(=O)Nc2cnccc2C)c1

EDJ-MED-e58735b6-1
0.427

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Cc1ccncc1NC(=O)Cc1cccc(CO)c1

EDJ-MED-e58735b6-2
0.425

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Cc1ccncc1NC(=O)C(C)c1cccc(C#N)c1

TRY-UNI-714a760b-22
0.423

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Cc1ccncc1NC(=O)NC1(Oc2ccccc2)CC1

CHR-SOS-1f323c23-10
0.421

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Cc1ccncc1NC(=O)Cc1cccc(F)c1

ALP-POS-95b75b4d-1
0.419

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Cc1ccncc1NC(=O)C(C#N)CC1CC1

MAT-POS-590ac91e-14
0.419

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Cc1ccncc1NC(=O)C(C)c1cncc(Cl)c1

TRY-UNI-2eddb1ff-3
0.419

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Cc1ccncc1NC(=O)CCOC1CC1

MAT-POS-590ac91e-10
0.417

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Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

SAM-UNK-2684b532-3
0.417

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Cc1nnc(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)s1

TRY-UNI-9f475305-3
0.417

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Cc1ccncc1NC(=O)CC1(CO)CC1

MAT-POS-590ac91e-6
0.414

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C=CC(=O)Nc1cnccc1C

MAK-UNK-6ca90168-27
0.413

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Cc1ccncc1NC(=O)NC1(Oc2ccccc2)CCCCC1

CHR-SOS-1f323c23-1
0.412

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Cc1ccncc1NC(=O)CC(C)C(C)C

MAT-POS-590ac91e-11
0.412

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Cc1ccncc1NC(=O)Cc1ccccc1N

ANN-UNI-98d2bf15-1
0.411

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Cc1ccncc1NC(=O)NCCCC(N)N

ALE-HEI-f28a35b5-11
0.411

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Cc1ccncc1NC(=O)C(C)C1CCCCC1

TRY-UNI-714a760b-16
0.411

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Cc1ccncc1NC(=O)NC1(Oc2ccccc2)CCC1

CHR-SOS-1f323c23-7
0.410

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COC1(CC(=O)Nc2cnccc2C)CC1

MAT-POS-590ac91e-9
0.408

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Cc1ccncc1NC(=O)CNC1(c2ccccc2)CCCCC1

WAR-XCH-e55cba98-11
0.407

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Cc1ccncc1NC(=O)C(C)c1cccc(C2(C)CC2)c1

DAR-DIA-0cde14eb-10
0.407

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Cc1ccncc1NC(=O)Cc1cccc(O)c1

ALP-POS-95b75b4d-2
0.405

View
Cc1ccncc1NC(=O)Cc1cccc(Cl)c1

TRY-UNI-714a760b-6
0.405

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Cc1ccncc1NC(=O)Cc1cccc(I)c1

JAN-GHE-83b26c96-13
0.405

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Cc1ccncc1NC(=O)NC1(Oc2ccccc2)CCCC1

CHR-SOS-1f323c23-4
0.405

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Cc1ccncc1NC(=O)Cc1cccc(C2CC2)c1

ALP-POS-95b75b4d-4
0.405

View
Cc1ccncc1NC(=O)C(C(=O)C(C)c1cccc(Cl)c1)c1cnccc1C

MAK-UNK-f203cb68-19
0.405

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(F)CC2)c1

DAR-DIA-0cde14eb-12
0.402

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(I)CC2)c1

DAR-DIA-0cde14eb-13
0.402

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(Cl)CC2)c1

DAR-DIA-0cde14eb-11
0.402

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CC(=O)N1CCN(C(C(=O)Nc2cnccc2C)c2cccc(Cl)c2)CC1

VLA-UCB-05e51b3f-2
0.400

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Cc1ccncc1NC(=O)CCc1ccccn1

BEN-DND-93268d01-4
0.400

View
COc1ccc(Br)cc1C(N)C(=O)Nc1cnccc1C

BAR-COM-0f94fc3d-58
0.400

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Cc1ccncc1NC(=O)Cc1cccc(Br)c1

JAN-GHE-83b26c96-12
0.400

View
Cc1ccncc1NC(=O)C(C)c1cnn(C2(I)CC2)c1

DAR-DIA-0cde14eb-73
0.395

View
COc1cc(Cl)cc(C(CCC2CCCCC2)C(=O)Nc2cnccc2C)c1

ALP-POS-3fc1724e-7
0.394

View
Cc1ccncc1NC(=O)Cc1cccc([S+](C)[O-])c1

DAR-DIA-0cde14eb-78
0.392

View
Cc1ccncc1NC(=O)CCCBr

ALE-HEI-f28a35b5-12
0.391

View
Cc1ccncc1NC(=O)CCc1ccccc1F

BEN-DND-93268d01-7
0.390

View
Cc1ccncc1NC(=O)NC1CCCCC1

TRY-UNI-714a760b-11
0.389

View
CC(C(=O)Nc1cnccc1O)c1ccccc1

BEN-DND-93268d01-15
0.389

View
Cc1ccncc1NC(=O)CC(O)C1CC1

MAT-POS-590ac91e-7
0.389

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Cc1ccncc1NC(=O)NC1CCCCC1

ALE-HEI-f28a35b5-7
0.389

View
Cc1ccncc1NC(=O)C(C)c1cccc(C2(C#N)CC2)c1

DAR-DIA-0cde14eb-15
0.388

View
Cc1ccncc1NC(=O)c1ccncc1NC(=O)Nc1ccccc1

MAK-UNK-129dcd6f-15
0.388

View
Cc1ccncc1NC(=O)Cc1cccc(OC(F)(F)F)c1

ANN-UNI-98d2bf15-5
0.388

View
Cc1ccncc1NC(=O)C(C)c1cc(Cl)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-8
0.386

View
Cc1ccncc1NC(=O)Nc1cncc(C#N)c1Oc1ccccc1

CHR-SOS-363cfb78-7
0.386

View
CCCCC(C(=O)Nc1cnccc1C)c1cc(Cl)cc(OC2CC(=O)N2)c1

JAN-GHE-f4ca5a00-15
0.385

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

ALP-POS-95b75b4d-3
0.385

View
Cc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)c1

DAR-DIA-0cde14eb-76
0.385

View
CCC(C(=O)Nc1cnccc1C)c1ccccc1

0.791

View
CCCC(C(=O)Nc1cnccc1C)c1ccccc1

0.739

View
Cc1ccncc1NC(=O)C(CC(C)C)c1ccccc1

0.739

View
Cc1ccncc1NC(=O)C(CC(F)(F)F)c1ccccc1

0.723

View
C=CCC(C(=O)Nc1cnccc1C)c1ccccc1

0.708

View
Cc1ccncc1NC(=O)C(CS(C)(=O)=O)c1ccccc1

0.708

View
COC(C(=O)Nc1cnccc1C)c1ccccc1

0.696

View
CO[C@@H](C(=O)Nc1cnccc1C)c1ccccc1

0.696

View
COCC(C)C(=O)Nc1cnccc1C

0.689

View
Cc1ccncc1NC(=O)C(c1ccccc1)c1ccccc1

0.682

View
C=CCCC(C(=O)Nc1cnccc1C)c1ccccc1

0.680

View
Cc1ccncc1NC(=O)C(CCS(C)(=O)=O)c1ccccc1

0.680

View
Cc1ccncc1NC(=O)C(CN1CCCC1)c1ccccc1

0.680

View
COCC(OC)C(=O)Nc1cnccc1C

0.674

View
COC[C@H](N)C(=O)Nc1cnccc1C

0.674

View
COCC(N)C(=O)Nc1cnccc1C

0.674

View
Cc1ccncc1NC(=O)C(C)C(N)c1ccccc1

0.674

View
Cc1ccncc1NC(=O)C(CNC(=O)OC(C)(C)C)c1ccccc1

0.673

View
Cc1ccncc1NC(=O)C(C)c1ccccc1

0.667

View
Cc1ccncc1NC(=O)[C@@H](C)c1ccccc1

0.667

View
Cc1ccncc1NC(=O)[C@H](C)c1ccccc1

0.667

View
Cc1ccncc1NC(=O)C(OC(C)C)c1ccccc1

0.667

View
COCC(C)C(C)C(=O)Nc1cnccc1C

0.660

View
CCOC(C(=O)Nc1cnccc1C)c1ccccc1

0.653

View
CCC(C(=O)Nc1cnccc1C)c1ccc(OC)cc1

0.653

View
Cc1ccncc1NC(=O)C(O)c1ccccc1

0.652

View
Cc1ccncc1NC(=O)C(F)c1ccccc1

0.652

View
Cc1ccncc1NC(=O)[C@@H](O)c1ccccc1

0.652

View
Cc1ccncc1NC(=O)[C@H](O)c1ccccc1

0.652

View
COC(=O)C(CNC(=O)Nc1cnccc1C)c1ccccc1

0.647

View
Cc1ccncc1NC(=O)C(N)C(C)c1ccccc1

0.646

View
CCC(C(=O)NNC(=O)Nc1cnccc1C)c1ccccc1

0.640

View
Cc1ccncc1NC(=O)CC(c1ccccc1)c1ccccc1

0.638

View
Cc1ccncc1NC(=O)C(c1ccccc1)C(C)C

0.638

View
CSC(C(=O)Nc1cnccc1C)c1ccccc1

0.638

View
CCC(C(=O)Nc1ccncc1C)c1ccccc1

0.638

View
COC(=O)C(CNC(=O)C(=O)Nc1cnccc1C)c1ccccc1

0.635

View
Cc1ccncc1NC(=O)C(Oc1ccccc1)c1ccccc1

0.633

View
CCC(C(=O)Nc1cnccc1OC)c1ccccc1

0.633

View
CCC(C(=O)NNC(=O)C(=O)Nc1cnccc1C)c1ccccc1

0.627

View
Cc1ccncc1NC(=O)C(c1ccccc1)N(C)C

0.625

View
CCc1ccccc1OC(C(=O)Nc1cnccc1C)c1ccccc1

0.623

View
CCC(C)C(C(=O)Nc1cnccc1C)c1ccccc1

0.620

View
CCN(CC)C(C(=O)Nc1cnccc1C)c1ccccc1

0.620

View
COC(Cc1ccccc1)C(=O)Nc1cnccc1C

0.620

View
Cc1ccncc1NC(=O)C(OC(C)(C)C)c1ccccc1

0.620

View
Cc1ccncc1NC(=O)CC(c1ccccc1)C(C)C

0.612

View
CCC(C(=O)Nc1cnccc1C)c1ccc(Br)cc1

0.612

View
Cc1ccncc1NC(=O)C(c1ccccc1)C1CC1

0.612

View
CCC(C(=O)Nc1cnccc1C)c1ccc(F)cc1

0.612

View
Cc1ccncc1NC(=O)NCC(c1ccccc1)c1ccccc1

0.612

View
CCN(C)C(C(=O)Nc1cnccc1C)c1ccccc1

0.608

View
CCC(C(=O)Nc1cnccc1C)c1cccc(Cl)c1

0.608

View
COCC(COC)NC(=O)Nc1cnccc1C

0.604

View
Cc1ccncc1NC(=O)C(Oc1ccccc1Br)c1ccccc1

0.604

View
COCC(Cc1ccccc1)NC(=O)Nc1cnccc1C

0.604

View
Cc1ccncc1NC(=O)C(Sc1ccccc1)c1ccccc1

0.600

View
COC(OC)C(=O)Nc1cnccc1C

0.600

View
CCCC(C(=O)Nc1ccncc1C)c1ccccc1

0.600

View
Cc1cnccc1NC(=O)C(CC(C)C)c1ccccc1

0.600

View
Cc1ccncc1NC(=O)C(=O)NCC(c1ccccc1)c1ccccc1

0.600

View
Cc1ccncc1NC(=O)COCC(C)c1ccccc1

0.596

View
CCCC(C(=O)Nc1cnccc1OC)c1ccccc1

0.596

View
COc1ccncc1NC(=O)C(CC(C)C)c1ccccc1

0.596

View
COC(CNC(=O)Nc1cnccc1C)c1ccccc1

0.596

View
COCC(Cc1ccccc1)NC(=O)C(=O)Nc1cnccc1C

0.593

View
CCC(C(=O)Nc1cnccc1O)c1ccccc1

0.592

View
Cc1ccncc1NC(=O)C(C)Oc1ccccc1

0.592

View
Cc1ccncc1NC(=O)CC(C)c1ccccc1

0.592

View
Cc1ccncc1NC(=O)C(C)Cc1ccccc1

0.592

View
Cc1ccncc1NC(=O)[C@H](C)Cc1ccccc1

0.592

View
Cc1ccncc1NC(=O)C(F)Cc1ccccc1

0.592

View
COCC(C)CC(=O)Nc1cnccc1C

0.592

View
COC[C@@H](C)NC(=O)Nc1cnccc1C

0.592

View
COC[C@H](C)NC(=O)Nc1cnccc1C

0.592

View
COCC(C)NC(=O)Nc1cnccc1C

0.592

View
COCC(COC)NC(=O)C(=O)Nc1cnccc1C

0.592

View
COCC(=O)Nc1cnccc1C

0.591

View
CCC(Oc1ccccc1)C(=O)Nc1cnccc1C

0.588

View
Cc1ccncc1NC(=O)C(NC(=O)c1ccccc1)c1ccccc1

0.588

View
Cc1ccncc1NC(=O)C(C)OCc1ccccc1

0.588

View
CCC(Sc1ccccc1)C(=O)Nc1cnccc1C

0.588

View
Cc1ccncc1NC(=O)[C@H](C)OCc1ccccc1

0.588

View
Cc1cnccc1NC(=O)C(CC(F)(F)F)c1ccccc1

0.588

View
CCC(C(=O)Nc1cnccc1OC(C)(C)C)c1ccccc1

0.588

View
Cc1ccncc1NC(=O)NCCC(c1ccccc1)c1ccccc1

0.588

View
COC(C)C(=O)Nc1cnccc1C

0.587

View
CO[C@H](C)C(=O)Nc1cnccc1C

0.587

View
Cc1ccncc1NC(=O)C(NC(=O)CC(C)C)c1ccccc1

0.585

View
COc1ccncc1NC(=O)C(CC(F)(F)F)c1ccccc1

0.585

View
COCC(NC(=O)Nc1cnccc1C)c1ccccn1

0.585

View
COC(CNC(=O)C(=O)Nc1cnccc1C)c1ccccc1

0.585

View
Cc1ccncc1NC(=O)[C@H](N)COCc1ccccc1

0.585

View
Cc1ccncc1NC(=O)[C@@H](N)COCc1ccccc1

0.585

View
CCC(OC)C(=O)Nc1cnccc1C

0.583

View
Cc1ccncc1NC(=O)NC(c1ccccc1)c1ccccc1

0.583

View
Cc1ccncc1NC(=O)C(NC(=O)OCc1ccccc1)c1ccccc1

0.582

View
COCCN(C(=O)Nc1cnccc1C)C(C)c1ccccc1

0.582

View
COCC(Cc1ccccc1)N(C)C(=O)Nc1cnccc1C

0.582

View
CCC(C(=O)Nc1cnccc1NC(C)=O)c1ccccc1

0.580

View

C(NC1=C(C)C=CN=C1)(=O)C(C)C1=CC=CC=C1

0.874

View
C(NC1=C(C)C=CN=C1)(=O)C(C1=CC=C(C)C=C1)C

0.847

View
C(NC1=C(C)C=CN=C1)(=O)C(C)C1=CC=C(F)C=C1

0.816

View
C(NC1=C(C)C=CN=C1)(=O)C(CC)C1=CC=CC=C1

0.815

View
C(NC1=C(C)C=CN=C1)(=O)C(C)C1=CC=C(Cl)C=C1

0.815

View


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