Molecule Details

Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1
piperazine-chloroacetamide Enamine Mcule MolPort
View on Fragalysis x0705
Molecular Properties
SMILES:
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1
MW: 280.755
Fraction sp3: 0.43
HBA: 2
HBD: 0
Rotatable Bonds: 2
TPSA: 40.62
cLogP: 1.51822
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-48205
Enamine SCR: Z561892132
Enamine REAL: Z1562125490
Enamine Extended REAL: m_270062____7601626____8147258
Mcule: MCULE-1155106631
MolPort: MolPort-002-503-201
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AHN-SAT-de2502ba-8
1.000

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N#Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-987948f6-3
0.627

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O=C(CCl)N1CCN(C(=O)c2ccccc2)CC1

MAK-UNK-987948f6-2
0.625

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Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1C

ASH-SAT-43770c7d-10
0.596

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O=C(CCl)N1CCN(C(=O)c2ccsc2)CC1

MAK-UNK-6ca90168-20
0.569

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O=C(CCl)N1CCN(C(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-5
0.538

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O=C(CCl)N1CCN(C(=O)c2cccc(Cl)c2)CC1

MAK-UNK-6ca90168-15
0.509

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Cc1ccc(C(=O)N2CCN(C(=O)CCl)C(CC(=N)N)C2)cc1

SEL-UNI-cd366922-1
0.477

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O=C(CCl)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-9
0.475

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27
0.474

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-68
0.474

View
O=C(CCl)N1CCN(C(=O)c2cc(O)cc(Cl)c2)CC1

SAD-SAT-581007d4-5
0.474

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O=C(CCl)N1CCN(C(=O)c2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-25
0.473

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O=C(CCl)N1CCN(C(=O)c2ccc(COc3ccc(N4CCN(C(=O)CCl)CC4)cc3)cc2)CC1

YOI-UNK-090ea88a-1
0.471

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O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

AAR-POS-d2a4d1df-29
0.455

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O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

MAR-TRE-6a44bbf2-61
0.455

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Cc1ccc(NC(=O)CN2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-12
0.450

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O=C(CCl)N1CCN(C(=O)c2cccs2)CC1

AAR-POS-0daf6b7e-16
0.446

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CC(=O)N1CCN(C(=O)CCl)CC1

AAR-POS-0daf6b7e-21
0.444

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Cc1ccc(CN2CCCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-21
0.443

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NS(=O)(=O)c1cc(Cl)cc(C(=O)N2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-6
0.435

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NC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-704ed37c-11
0.435

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Cc1ccc(C(=O)N2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-3f402c2b-4
0.433

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Cc1ccc(C(c2ccccc2)N2CCN(C(=O)CCl)CC2)cc1

GIA-UNK-7337c2f3-7
0.429

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O=C(CCl)N1CCN(C(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-4
0.429

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Cc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-11
0.424

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O=C(CCl)N1CCN(C(=O)c2cscc2Cl)CC1

SAD-SAT-1b030f84-5
0.421

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O=C(CCl)N1CCN(C(=O)C2=CC[SH]=C2)CC1

SAD-SAT-3a925b8b-1
0.421

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Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.417

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Cc1ccccc1CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-10
0.414

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O=C(CCl)N1CCN(C(=O)c2cccc3ccccc23)CC1

MAK-UNK-6ca90168-1
0.413

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CC(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-987948f6-5
0.408

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Cc1cccc(N2CCN(C(=O)CCl)CC2)c1

SAD-SAT-5b1897b2-4
0.407

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Cc1ccc(C(c2cccc(C)c2)N2CCN(C(=O)CCl)CC2)cc1

MED-COV-4280ac29-23
0.403

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N#CCC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-18
0.400

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CNC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-704ed37c-12
0.400

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CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-13
0.393

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Cc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-2
0.393

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CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-78
0.393

View
Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-4
0.393

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Cc1ccccc1CN1CCN(C(=O)CCl)CC1

MAK-UNK-7c9d1431-20
0.393

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O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.393

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C=C(C)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-987948f6-4
0.392

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Cc1ccc(S(=O)(=O)NC2CCN(C(=O)CCl)CC2)cc1

WAR-XCH-79d12f6e-4
0.391

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1

AAR-POS-d2a4d1df-36
0.391

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

AAR-POS-0daf6b7e-3
0.391

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

WAR-XCH-79d12f6e-6
0.391

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Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-13
0.391

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

MAK-UNK-212f693e-8
0.390

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O=C(CCl)N1CCN(Cc2ccsc2)CC1

AAR-POS-0daf6b7e-13
0.390

View
O=C(CCl)N1CCN(c2cccc(Cl)c2)CC1

SAD-SAT-65574d3f-9
0.390

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O=C(CCl)N1CCN(Cc2ccsc2)CC1

LON-WEI-8f408cad-7
0.390

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O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.386

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Cc1cccc(C)c1NC(=O)CN1CCN(C(=O)CCl)CC1

TAT-ENA-80bfd3e5-30
0.385

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O=C(CCl)N1CCCN(C(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-8
0.381

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C=CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-16
0.380

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Cc1cc(CN2CCN(C(=O)CCl)CC2)cc(S(N)(=O)=O)c1

SAD-SAT-581007d4-4
0.379

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O=C(CCl)N1CCCC1

MAK-UNK-4b073b5c-16
0.378

View
CCNC(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-bf9c9ac8-2
0.377

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CC(C)N(C)C(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-bf9c9ac8-1
0.377

View
CC(C)N(C)C(=O)N1CCN(C(=O)CCl)CC1

YOI-UNK-15f562e8-4
0.377

View
Cc1ccc(CN2CCN(C(=O)CCl)CC2)o1

MAR-LAB-ca4662a6-2
0.377

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N#CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-17
0.373

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CC(C)NC(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-9a3d118a-1
0.370

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COc1ccc(N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-0daf6b7e-18
0.367

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2)CC1

AHN-SAT-de2502ba-7
0.367

View
O=C(CCl)N1CCN(C(=O)N2CCCC2)CC1

MAK-UNK-704ed37c-10
0.365

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NS(=O)(=O)CC(=O)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-8
0.365

View
O=C(CCl)N1CCN(C(=O)C2CC2)CC1

SAD-SAT-5b1897b2-9
0.365

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N#Cc1ccccc1CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-9
0.365

View
O=C(CCl)N1CCN(C(=O)n2cccc2)CC1

MAK-UNK-52a1ef4b-1
0.364

View
Cc1cccc(NC2CCN(C(=O)CCl)CC2)c1

NIR-THE-0d6461ce-1
0.364

View
CC(C)(C)NC(=O)CN1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-56
0.362

View
O=C(CCl)N1CCCCC1

SAD-SAT-d8079f6f-3
0.362

View
O=C(CCl)N1CCCCCC1

SAD-SAT-d8079f6f-5
0.362

View
Cc1cc(C)cc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)c1

NIM-UNI-05f93fcc-7
0.361

View
N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-6ca90168-14
0.361

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-7c9d1431-8
0.359

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAR-TRE-6a44bbf2-26
0.359

View
CN1CCN(C(=O)c2ccc3c(c2)CCN(C(=O)CCl)C3)CC1

ALE-SYG-bac15da4-2
0.357

View
O=C(CCl)N1CCN(C(=O)N2C=CSC2)CC1

MAK-UNK-52a1ef4b-2
0.356

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.356

View
O=C(CCl)N1CCN(C(c2ccccc2)c2ccccc2)CC1

SIM-SYN-f15aaa3a-1
0.356

View
Cc1ccc(CCC(c2cccc(Cl)c2)N2CCN(C(=O)CCl)CC2)cc1

PAU-WEI-b9b69149-3
0.355

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3
0.355

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

MAR-TRE-6a44bbf2-52
0.355

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-15
0.355

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15
0.355

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)CC1

MAT-POS-ee51dedd-2
0.355

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

AAR-POS-d2a4d1df-22
0.355

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

AAR-POS-d2a4d1df-35
0.355

View
O=C(CCl)N1CCN(Oc2ccsc2)CC1

MAK-UNK-212f693e-9
0.355

View
O=C(CCl)N1CCCCCCC1

SAD-SAT-d8079f6f-6
0.354

View
O=C(CCl)N1CCN(C(=O)N2CCCCCC2)CC1

MAK-UNK-704ed37c-13
0.352

View
O=C(CCl)N1CCN(c2ccccc2F)CC1

SAD-SAT-5b1897b2-10
0.350

View
O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAR-TRE-6a44bbf2-28
0.349

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-1
0.349

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Br)s2)CC1

NIM-UNI-05f93fcc-1
0.349

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-d2e6fa14-1
0.349

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

LON-WEI-8f408cad-2
0.349

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCl)CC2)C=C1

1.000

View
CC1=CC=C(C(=O)N2CCN(C(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.725

View
CCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.717

View
CC1=CC=C(C(=O)N2CCN(C(=O)CO)CC2)C=C1

0.717

View
CC1=CC=C(C(=O)N2CCN(C(=O)CN)CC2)C=C1

0.702

View
CCCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.688

View
CSCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.688

View
O=C(CCl)N1CCN(C(=O)C2=CC=C(Cl)C=C2)CC1

0.681

View
O=C(CCl)N1CCN(C(=O)C2=CC=C(O)C=C2)CC1

0.681

View
CCC1=CC=C(C(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.673

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC(C)C)CC2)C=C1

0.673

View
CC(=O)CCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.673

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCO)CC2)C=C1

0.673

View
O=C(CCl)N1CCN(C(=O)C2=CC=C(F)C=C2)CC1

0.667

View
O=C(CCl)N1CCN(C(=O)C2=CC=C(Br)C=C2)CC1

0.667

View
COC1=CC=C(C(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.660

View
CC1=CC=C(C(=O)N2CCN(C(=O)CN(C)C)CC2)C=C1

0.660

View
CNCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.660

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC#N)CC2)C=C1

0.660

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC(C)(C)C)CC2)C=C1

0.660

View
COCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.660

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCN)CC2)C=C1

0.660

View
C=C(Cl)CCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.654

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC(F)(F)F)CC2)C=C1

0.647

View
CC1=CC=C(C(=O)N2CCN(C(=O)CS(C)(=O)=O)CC2)C=C1

0.647

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCC(=O)O)CC2)C=C1

0.647

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3CC3)CC2)C=C1

0.647

View
CC1=CC=C(C(=O)N2CCN(C(=O)CON)CC2)C=C1

0.647

View
CC1=CC=C(C(=O)N2CCN(C(=O)C[C@@H](C)N)CC2)C=C1

0.647

View
CC1=CC=C(C(=O)N2CCN(C(=O)C[C@H](C)N)CC2)C=C1

0.647

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC(C)N)CC2)C=C1

0.647

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC(C)(C)O)CC2)C=C1

0.647

View
CC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.644

View
CC1=CC=C(C(=O)N2CCN(C(=O)COC(C)(C)C)CC2)C=C1

0.642

View
CC1=CC=C(C(=O)N2CCN(C(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.638

View
CC1=CC=C(CC(=O)N2CCN(C(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.635

View
CCC(CC)CC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.635

View
CC1=CC=C(C(=O)CCC(=O)N2CCN(C(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.635

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCC(N)=O)CC2)C=C1

0.635

View
CCCCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.635

View
CC(=O)NCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.635

View
COC(=O)CC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.635

View
CCSCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.635

View
C=C(C)CCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.635

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC(C)(F)F)CC2)C=C1

0.635

View
CC1=CC=C(C(=O)N2CCN(C(=O)CSC(C)C)CC2)C=C1

0.635

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC(C)(C)N)CC2)C=C1

0.635

View
CC1=CC=C(C(=O)N2CCN(C(=O)C(=O)N3CCN(C(=O)C4=CC=C(C)C=C4)CC3)CC2)C=C1

0.630

View
O=C(CCl)N1CCN(C(=O)C2=CC=C(C(F)(F)F)C=C2)CC1

0.627

View
O=C(CCl)N1CCN(C(=O)C2=CC=CC=C2)CC1

0.625

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCC(C)C)CC2)C=C1

0.623

View
CCNCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.623

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3(C)CC3)CC2)C=C1

0.623

View
CCOCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.623

View
CC(=O)CCCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.623

View
COCCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.623

View
CCN(CC)CC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.623

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC(=O)N(C)C)CC2)C=C1

0.623

View
CSCCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.623

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCC(C)(C)C)CC2)C=C1

0.623

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCCN)CC2)C=C1

0.623

View
CC1=CC=C(C(=O)N2CCN(C(=O)CN3C(=O)CCC3=O)CC2)C=C1

0.618

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3=CC(C)=CC(C)=C3)CC2)C=C1

0.618

View
CC(=O)C1=CC=C(C(=O)N2CCN(C(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.617

View
CCCC(CCC)CC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.611

View
CC1=CC=C(C(=O)N2CCN(C(=O)CN3CCCC3)CC2)C=C1

0.611

View
CCCCCC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.611

View
CC1=CC=C(C(=O)N2CCN(C(=O)CSC(F)F)CC2)C=C1

0.611

View
CC1=CC=C(C(=O)N2CCN(C(=O)CNC(C)(C)C)CC2)C=C1

0.611

View
CCC(C)(C)CC(=O)N1CCN(C(=O)C2=CC=C(C)C=C2)CC1

0.611

View
CC1=CC=C(C(=O)N2CCCN(C(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.609

View
CC1=CC=C(C(=O)N2CCN(C(=O)C3=CC=CC=C3)CC2)C=C1

0.604

View
CCC(=O)N1CCCN(C(=O)C2=CC=C(C)C=C2)CC1

0.604

View
CC1=CC=C(SCC(=O)N2CCN(C(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.600

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCC(=O)N3CCOCC3)CC2)C=C1

0.600

View
CC1=CC=C(C(=O)N2CCN(C(=O)COCC(=O)O)CC2)C=C1

0.600

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3=CC=C(Cl)C=C3)CC2)C=C1

0.596

View
CC1=CC=C(C(=O)N2CCN(C)CC2)C=C1

0.596

View
CC1=CC=C(OCC(=O)N2CCN(C(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.589

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3=CC=CC=C3)CC2)C=C1

0.589

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3=C(Cl)C=CC=C3Cl)CC2)C=C1

0.586

View
CC1=CC=C(C(=O)N2CCN(S(=O)(=O)CCl)CC2)C=C1

0.585

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3=C(C)C=C(C)C=C3C)CC2)C=C1

0.579

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3=C(C)C=CC=C3C)CC2)C=C1

0.579

View
CC1=CC=C(C(=O)N2CCN(CC(=O)N3CCC3)CC2)C=C1

0.574

View
CC1=CC=C(C(=O)N2CCCN(C(=O)CC(C)C)CC2)C=C1

0.571

View
CC1=CC=C(OCCC(=O)N2CCN(C(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.569

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3=C(F)C=CC=C3F)CC2)C=C1

0.569

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCl)CC2)C=C1F

0.564

View
CC1=CC=C(C(=O)N2CCN(CC(=O)N3CCCC3)CC2)C=C1

0.564

View
CC1=CC=C(C(=O)N2CCN(C(=O)COC3=CC=C(Cl)C=C3)CC2)C=C1

0.557

View
CC1=CC=C(C(=O)N2CCN(C(=O)CC3=C(C)C=CC=C3Cl)CC2)C=C1

0.557

View
O=C(CCl)N1CCCN(C(=O)C2=CC=C(Cl)C=C2)CC1

0.545

View
CC1=CC=C(CC(=O)N2CCN(C(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.542

View
CC1=CC=C(CC(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.538

View
CC1=CC=C(C(=O)N2CCN(C3=CC=C(C)C=C3)CC2)C=C1

0.538

View
O=C(CCl)N1CCCN(C(=O)C2=CC=C(F)C=C2)CC1

0.536

View
CC1=CC=C(C(=O)N2CCN(C(=O)CCC(=O)N3CCN(C4=CC=CC=C4)CC3)CC2)C=C1

0.532

View
CC1=CC=C(OCC(=O)N2CCN(C(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.508

View
O=C(CCl)N1CCCN(C(=O)C2=CC=CC=C2)CC1

0.500

View
Cc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)CCl

1.000

View
Cc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1ccc(C)cc1

0.725

View
CCC(=O)N1CCN(CC1)C(=O)c1ccc(C)cc1

0.717

View
CC(=O)N1CCN(CC1)C(=O)c1ccc(C)cc1

0.644

View
ClCC(=O)N1CCN(CC1)C(=O)c1ccccc1

0.625

View
Cc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1ccccc1

0.604

View
Cc1ccc(CN2CCN(CC2)C(=O)c2ccc(C)cc2)cc1

0.596

View
CN1CCN(CC1)C(=O)c1ccc(C)cc1

0.596

View
CCN1CCN(CC1)C(=O)c1ccc(C)cc1

0.592

View
Cl.CN1CCN(CC1)C(=O)c1ccc(C)cc1

0.583

View
Cc1ccc(cc1)C(=O)N1CCN(CC1)C=O

0.560

View
CCCN1CCN(CC1)C(=O)c1ccc(C)cc1

0.558

View
Cc1ccc(cc1)C(=O)N1CCN(CCO)CC1

0.558

View
Cc1ccc(cc1)C(=O)N1CCN(Cc2ccccc2)CC1

0.554

View
Cc1ccc(cc1)C(=O)N1CCNCC1

0.551

View
Cl.Cc1ccc(cc1)C(=O)N1CCN(CCO)CC1

0.547

View
Cl.Cc1ccc(cc1)C(=O)N1CCNCC1

0.540

View
Cc1ccc(cc1)C(=O)N1CCN(CC=C)CC1

0.537

View
Cc1ccc(cc1)C(=O)N1CCN(Cc2ccc(cc2)C#N)CC1

0.508

View
Cc1ccc(cc1)C(=O)NCCN1CCN(CC1)C(=O)c1ccc(C)cc1

0.500

View
CCc1ccc(cc1)C(=O)N1CCN(Cc2ccc(C)cc2)CC1

0.492

View
Cc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1ccc2ccccc2c1

0.492

View
Cc1ccc(CN2CCN(CC2)C(=O)c2ccccc2)cc1

0.450

View
CN1CCN(CC1)C(=O)c1ccc(cc1)C(=O)N1CCN(C)CC1

0.438

View
CCc1ccc(cc1)C(=O)N1CCN(CC1)C(C)=O

0.426

View
CC(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(N)=O

0.415

View
O=C(N1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(=O)N1CCN(Cc2ccccc2)CC1

0.404

View
CCc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1ccccc1

0.404

View
Cl.Cl.O=C(N1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C(=O)N1CCN(Cc2ccccc2)CC1

0.397

View
O=C(N1CCN(CC1)C(=O)c1ccccc1)c1ccccc1

0.396

View
ClCC(=O)N1CCN(Cc2ccccc2)CC1

0.393

View
CC(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C#N

0.393

View
CCc1ccc(cc1)C(=O)N1CCN(C)CC1

0.393

View
CN1CCN(CC1)C(=O)c1ccc(CO)cc1

0.393

View
CC(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C(F)(F)F

0.393

View
CN1CCN(CC1)C(=O)c1ccc(CN)cc1

0.386

View
Cl.ClCC(=O)N1CCN(Cc2ccccc2)CC1

0.386

View
CCN1CCN(CC1)C(=O)c1ccc(CC)cc1

0.386

View
CC(=O)N1CCN(CC1)C(=O)c1ccccc1

0.377

View
Cc1ccc(cc1)C(=O)NCC(=O)N1CCN(Cc2ccccc2)CC1

0.377

View
CCc1ccc(cc1)C(=O)N1CCN(Cc2ccccc2)CC1

0.375

View
CCN1CCN(CC1)C(=O)c1ccc(cc1)C#N

0.373

View
CN1CCN(CC1)C(=O)c1ccc(cc1)C#N

0.362

View
Cl.CC(C)N1CCN(CC1)C(=O)c1ccc(CN)cc1

0.361

View
Cl.CCN1CCN(CC1)C(=O)c1ccc(cc1)C(F)(F)F

0.361

View
Cl.CN1CCN(CC1)C(=O)c1ccc(cc1)C#N

0.356

View
O=C(N1CCN(CC1)C(=O)c1ccc(cc1)C#N)c1ccccc1

0.356

View
Cl.CCc1ccc(cc1)C(=O)N1CCNCC1

0.356

View
Cl.CN1CCN(CC1)C(=O)c1ccc(cc1)C(F)(F)F

0.356

View
CCN(Cc1ccc(cc1)C(=O)N1CCN(CC1)C(C)=O)C(C)C

0.354

View
CCN1CCN(CC1)C(=O)c1ccccc1

0.351

View
Cl.ClCCN1CCN(CC1)C(=O)c1ccccc1

0.350

View
O=C(N1CCN(Cc2ccccc2)CC1)c1ccccc1

0.350

View
ClC(=C)CN1CCN(CC1)C(=O)c1ccccc1

0.344

View
O=C(N1CCN(Cc2ccccc2)CC1)c1ccc(cc1)C#N

0.343

View
CCc1ccc(CN2CCN(CC2)C(=O)c2ccccc2)cc1

0.338

View
O=C(N1CCN(CCN2CCN(CC2)C(=O)c2ccccc2)CC1)c1ccccc1

0.333

View
Cl.Cl.NCc1ccc(cc1)C(=O)N1CCN(CC1)C1CC1

0.333

View
CCCN1CCN(CC1)C(=O)c1ccccc1

0.333

View
FC(F)(F)c1ccc(cc1)C(=O)N1CCN(CC1)C=O

0.328

View
Cl.NC(=O)c1ccc(cc1)C(=O)N1CCNCC1

0.328

View
CC(C)N1CCN(CC1)C(=O)c1ccccc1

0.328

View
Cc1ccc(cc1)C(=O)NCCNC(=O)c1ccc(C)cc1

0.327

View
CCN(CC)CCN1CCN(CC1)C(=O)c1ccccc1

0.318

View
CN1CCN(CCNC(=O)c2ccc(C)cc2)CC1

0.317

View
O=C(N1CCN(Cc2ccc(cc2)C#N)CC1)c1ccccc1

0.304

View
O=C(N1CCN(CCN2CCNCC2)CC1)c1ccccc1

0.303

View
O=C(N1CCNCC1)c1ccccc1

0.298

View
CCN(CC)Cc1ccc(cc1)C(=O)NCc1ccc(cc1)C(=O)N1CCN(C)CC1

0.295

View
Cl.O=C(N1CCNCC1)c1ccccc1

0.293

View
CN(C)CCNC(=O)c1ccc(C)cc1

0.293

View
O=C(NCCN1CCN(CC1)C(=O)c1ccccc1)c1ccccc1

0.290

View
Cc1ccc(cc1)C(=O)NCCNC(=O)c1ccccc1

0.283

View
CCNC(=O)c1ccc(CN2CCN(Cc3ccccc3)CC2)cc1

0.211

View
CN1CCN(CCNC(=O)c2ccc(cc2)C(=O)NC(C)(C)C)CC1

0.205

View
CN1CCN(CCNC(=O)c2ccccc2)CC1

0.186

View
CCN(CC)CCNC(=O)c1ccc(cc1)C(=O)NCCN(CC)CC

0.177

View
CC(C)N(CCNC(=O)c1ccc(cc1)C(=O)NCCN(C(C)C)C(C)C)C(C)C

0.175

View
Cl.Cl.CN(C)CCNC(=O)c1ccc(CN)cc1

0.162

View
CN(C)Cc1ccc(cc1)C(=O)NCCNC(C)=O

0.157

View
Cl.Cl.CCN(CC)CCNC(=O)c1ccc(CN)cc1

0.153

View
Cl.Cl.CN(CCNC(=O)c1ccc(cc1)C(=O)NCCN(C)Cc1ccccc1)Cc1ccccc1

0.151

View
CCN(CCN(C)CC=C)C(=O)c1ccc(cc1)C(N)=O

0.132

View
C(N1CCN(C(C)=O)CC1)(=O)C1=CC=C(C)C=C1

0.945

View
C(N1CCN(C(C2=CC=C(C)C=C2)=O)CC1)(C(Cl)Cl)=O

0.928

View
C(N1CCN(C(C)=O)CC1)(=O)C1=CC=C(C=O)C=C1

0.927

View
C(N1CCN(C=O)CC1)(=O)C1=CC=C(C)C=C1

0.926

View
C(N1CCN(C=O)CC1)(=O)C1=CC=C(C=O)C=C1

0.911

View

Discussion: