Molecule Details

O=C(CCl)N1CCN(C(=O)c2ccco2)CC1
piperazine-chloroacetamide Enamine Mcule MolPort
View on Fragalysis x0736
Molecular Properties
SMILES:
O=C(CCl)N1CCN(C(=O)c2ccco2)CC1
MW: 256.689
Fraction sp3: 0.45
HBA: 3
HBD: 0
Rotatable Bonds: 2
TPSA: 53.76
cLogP: 0.8028
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-01858
Enamine SCR: Z56896179
Enamine REAL: Z56896179
Enamine Extended REAL: m_270062____7594928____8147258
Mcule: MCULE-5737028138
MolPort: MolPort-002-001-394
O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

MAR-TRE-6a44bbf2-61
1.000

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O=C(CCl)N1CCN(C(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-5
0.509

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N#CC1CN(C(=O)c2ccco2)CCN1C(=O)CCl

MAK-UNK-987948f6-9
0.508

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O=C(CCl)N1CCN(C(=O)c2ccccc2)CC1

MAK-UNK-987948f6-2
0.500

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O=C(CCl)N1CCN(Cc2ccco2)CC1

MAK-UNK-7c9d1431-28
0.482

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O=C(CCl)N1CCN(C(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-4
0.481

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O=C(CCl)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-9
0.475

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O=C(CCl)N1CCN(C(=O)c2cccs2)CC1

AAR-POS-0daf6b7e-16
0.473

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O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.472

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N#CCC1CN(C(=O)c2ccco2)CCN1C(=O)CCl

MAK-UNK-987948f6-8
0.470

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O=C(CCl)N1CCN(C(=O)c2cccc(Cl)c2)CC1

MAK-UNK-6ca90168-15
0.456

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O=C(CCl)N1CCN(C(=O)c2ccsc2)CC1

MAK-UNK-6ca90168-20
0.455

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Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-25
0.455

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Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AHN-SAT-de2502ba-8
0.455

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O=C(CCl)N1CCN(C(=O)c2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-25
0.446

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O=C(CCl)N1CCN(C(=O)C2=CC[SH]=C2)CC1

SAD-SAT-3a925b8b-1
0.446

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O=C(SCF)C1CCN(C(=O)c2ccco2)CC1

GIA-UNK-995df016-11
0.443

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NC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-704ed37c-11
0.435

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O=C(CCl)N1CC2CC1CN2C(=O)c1ccco1

MAK-UNK-3f402c2b-7
0.433

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N#Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-987948f6-3
0.431

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Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1C

ASH-SAT-43770c7d-10
0.431

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O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15
0.424

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O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

AAR-POS-d2a4d1df-35
0.424

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O=C(CCl)N1CCN(C(=O)c2cscc2Cl)CC1

SAD-SAT-1b030f84-5
0.421

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Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.417

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CC(=O)N1CCN(C(=O)CCl)CC1

AAR-POS-0daf6b7e-21
0.413

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CN(C)Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

JOK-SYG-18591e8f-1
0.413

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O=C(CCl)N1CCN(C(=O)c2cccc3ccccc23)CC1

MAK-UNK-6ca90168-1
0.413

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O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.411

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O=C(CCl)N1CCN(C(=O)CC(CCc2ccccc2)N2CCN(C(=O)CCl)CC2)CC1

AHN-SAT-de2502ba-1
0.409

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C=CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-16
0.408

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O=C(CCl)N1CCCN(C(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-8
0.403

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Cc1ccc(Cn2c(=O)c(=O)n(CC(=O)N3CCN(C(=O)c4ccco4)CC3)c3cccnc32)cc1

MAR-TRE-4b834d9a-51
0.400

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O=C(CCl)N1CCN(C(=O)c2cc(O)cc(Cl)c2)CC1

SAD-SAT-581007d4-5
0.400

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N#CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-17
0.400

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Cn1cc(NC(=O)N2CCN(C(=O)c3ccco3)CC2)c2ccccc2c1=O

MAT-POS-b5746674-36
0.397

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CC(CCc1ccccc1)N1CCN(C(=O)CCl)CC1

MAK-UNK-af83ef51-2
0.397

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CSCCC(NS(=O)(=O)/C=C/c1ccccc1)C(=O)N1CCN(C(=O)c2ccco2)CC1

TAT-ENA-80bfd3e5-41
0.395

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O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAR-TRE-6a44bbf2-28
0.393

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O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAK-UNK-7c9d1431-23
0.393

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O=C(CCl)N1CCN(Cc2ccsc2)CC1

MAK-UNK-212f693e-8
0.390

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O=C(CCl)N1CCN(Cc2ccsc2)CC1

AAR-POS-0daf6b7e-13
0.390

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O=C(CCl)N1CCN(C(=O)Nc2ccccc2)CC1

AHN-SAT-de2502ba-7
0.390

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Cc1ccccc1CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-10
0.390

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O=C(CCl)N1CCN(Cc2ccsc2)CC1

LON-WEI-8f408cad-7
0.390

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O=C(CCl)N1CCN(C(=O)n2cccc2)CC1

MAK-UNK-52a1ef4b-1
0.389

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CN1CCN(C(=O)COc2ccc(C3CN(C(=O)c4ccco4)CCN3C(=O)CCl)cc2)CC1

RAF-UNK-9885c2f5-1
0.388

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O=C(CCl)N1CCN(CCCc2ccccc2)CC1

MAK-UNK-15efde89-1
0.387

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N#CC(CCc1ccccc1)N1CCN(C(=O)CCl)CC1

MAK-UNK-10dfa458-39
0.385

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N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAT-POS-ee51dedd-1
0.385

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N#Cc1nc(-c2ccco2)oc1N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-1
0.384

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O=C(CCl)N1CCN(Cc2cccs2)CC1

LON-WEI-8f408cad-5
0.383

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O=C(CCl)N1CCN(Cc2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-2
0.383

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O=C(CCl)N1CCN(Cc2cccs2)CC1

AAR-POS-0daf6b7e-17
0.383

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N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-6ca90168-14
0.383

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CC(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-987948f6-5
0.380

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O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.379

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O=C(CCl)N1CCN(C(c2ccccc2)c2ccccc2)CC1

SIM-SYN-f15aaa3a-1
0.379

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O=C(CCl)N1CCN(S(=O)(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-2
0.377

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O=C(CCl)N1CCN(c2ccccc2F)CC1

SAD-SAT-5b1897b2-10
0.373

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N#CCC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-18
0.373

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CNC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-704ed37c-12
0.373

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O=C(CCl)N1CCN(C(c2cccc(Cl)c2)c2cccc(Cl)c2)CC1

MED-COV-4280ac29-6
0.371

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O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-1
0.371

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O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-d2e6fa14-1
0.371

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Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-4
0.371

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O=C(CCl)N1CCN(Cc2ccc(CS(=O)(=O)F)cc2)CC1

JIA-UNI-93b03cae-1
0.371

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NS(=O)(=O)c1cc(Cl)cc(C(=O)N2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-6
0.369

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Cc1cccc(CC2CCN(C(=O)CCl)CC2)c1

MAK-UNK-af83ef51-6
0.369

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C=Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-3
0.369

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O=C(CCl)N1CCN(c2ncccn2)CC1

VIK-SYN-9a3d118a-4
0.368

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O=C(CCl)N1CCN(c2ncccn2)CC1

MAR-TRE-6a44bbf2-87
0.368

View
O=C(CCl)N1CCN(c2ncccn2)CC1

VIK-SYN-bf9c9ac8-7
0.368

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAR-TRE-6a44bbf2-21
0.367

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O=C(CCl)N1CCN(c2ccccn2)CC1

SAD-SAT-5b1897b2-3
0.367

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O=C(CCl)N1CCN(c2cccc(Cl)c2)CC1

SAD-SAT-65574d3f-9
0.367

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAK-UNK-7c9d1431-9
0.367

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O=C(CCl)N1CCN(C(=O)N2CCCC2)CC1

MAK-UNK-704ed37c-10
0.365

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C=C(C)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-987948f6-4
0.365

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NS(=O)(=O)CC(=O)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-8
0.365

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O=C(CCl)N1CCN(C(=O)C2CC2)CC1

SAD-SAT-5b1897b2-9
0.365

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N#Cc1ccccc1CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-9
0.365

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O=C(CCl)N1CCN(Cc2ccc3c(c2)OCO3)CC1

MAK-UNK-7c9d1431-14
0.364

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O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAR-TRE-6a44bbf2-54
0.364

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O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAK-UNK-7c9d1431-16
0.364

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O=C(CCl)N1CCN([C@@H](c2cccc(Cl)c2)c2ccc(Cl)s2)CC1

SEA-TRI-8222e606-1
0.361

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Cc1cccc(N2CCN(C(=O)CCl)CC2)c1

SAD-SAT-5b1897b2-4
0.361

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O=C(CCl)N1CCN(Cc2cccc(CNC(=O)N3CCOCC3)c2)CC1

TAM-UNI-d1c3dd9f-12
0.360

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COCc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

MED-COV-4280ac29-33
0.358

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O=C(CCl)N1CCN(Cc2cn(Cc3ccccc3)nn2)CC1

STE-KUL-2e0d2e88-7
0.357

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O=C(CCl)N1CCN(C(=O)N2C=COC2)CC1

MAK-UNK-52a1ef4b-3
0.356

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3
0.355

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

MAR-TRE-6a44bbf2-52
0.355

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Cc1ccc(CN2CCN(C(=O)CCl)CC2)o1

MAR-LAB-ca4662a6-2
0.355

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-15
0.355

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

AAR-POS-0daf6b7e-12
0.355

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

AAR-POS-d2a4d1df-22
0.355

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-23
0.355

View
O=C(CCl)N1CCN(C2(c3ccccc3)CCCCC2)CC1

WAR-XCH-79d12f6e-7
0.354

View
O=C(CCl)N1CCN(Cc2cnc(-c3ccccc3)nc2)CC1

MAK-UNK-af83ef51-1
0.353

View
O=C(CCl)N1CCN(C(=O)C2=CC=CO2)CC1

1.000

View
O=C(CO)N1CCN(C(=O)C2=CC=CO2)CC1

0.717

View
CCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.702

View
NCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.702

View
O=C(CCO)N1CCN(C(=O)C2=CC=CO2)CC1

0.688

View
O=C(CCCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.673

View
O=C(CCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.673

View
O=C(CSCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.673

View
O=C(COCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.673

View
NCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.673

View
CSCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.673

View
CCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.660

View
CC(=O)CCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.660

View
C=C(Cl)CCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.654

View
C=CCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.654

View
O=C(CCCCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
O=C(CCCCCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
O=C(CC1CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
CN(C)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
COCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
O=C(CC(F)(F)F)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
N#CCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
CC(C)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
CC(C)(C)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
CNCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
NOCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.647

View
O=C(CN1CCN(C(=O)C2=CC=CO2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.635

View
NC(=O)CCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.635

View
CS(=O)(=O)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.635

View
CC(C)(O)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.635

View
O=C(C(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.630

View
CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.630

View
NC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.630

View
CC(C)(C)OCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.630

View
O=C(CC1=CC=CO1)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
O=C(CC1=CC=CC=C1)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
O=C(CN1CCCC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
CCC(=O)N1CCN(C(=O)C(=O)N2CCN(C(=O)C3=CC=CO3)CC2)CC1

0.623

View
O=C(CC1CCC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
CCCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
C[C@H](N)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
C[C@@H](N)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
NCCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
CC(N)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
CCOCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
COC(=O)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
O=C(CSC(F)F)N1CCN(C(=O)C2=CC=CO2)CC1

0.623

View
O=C(CC(O)C(Cl)(Cl)Cl)N1CCN(C(=O)C2=CC=CO2)CC1

0.618

View
O=C(CC1CC1(Cl)Cl)N1CCN(C(=O)C2=CC=CO2)CC1

0.618

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CCC(CC)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.611

View
O=C(CCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCOCC1

0.611

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CC(C)CCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.611

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O=C(O)COCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.611

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NC(=O)CSCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.611

View
CSCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.611

View
COCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.611

View
O=C(CC(F)(F)C(F)(F)F)N1CCN(C(=O)C2=CC=CO2)CC1

0.611

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CC(=O)CCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.611

View
O=C(C1=CC=CO1)N1CCCN(C(=O)C2=CC=CO2)CC1

0.609

View
O=C(CC1=CC=C(Cl)C=C1)N1CCN(C(=O)C2=CC=CO2)CC1

0.607

View
O=C(C1=CC=C(C(=O)N2CCN(C(=O)C3=CC=CO3)CC2)C=C1)N1CCN(C(=O)C2=CC=CO2)CC1

0.604

View
O=C(CC1CCCC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.600

View
O=C(CN1CCCCCC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.600

View
CCCCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.600

View
O=C(CCC1CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.600

View
O=C(CC1OCCO1)N1CCN(C(=O)C2=CC=CO2)CC1

0.600

View
O=C(CC1=C(Cl)C=CC=C1Cl)N1CCN(C(=O)C2=CC=CO2)CC1

0.596

View
O=C(CC1=CC(Cl)=CC(Cl)=C1)N1CCN(C(=O)C2=CC=CO2)CC1

0.596

View
CCC(=O)N1CCCN(C(=O)C2=CC=CO2)CC1

0.593

View
O=C(C1=CC=CO1)N1CCN(CCN2CCN(C(=O)C3=CC=CO3)CC2)CC1

0.592

View
O=C(C1=CC=CO1)N1CCNCCN(C(=O)C2=CC=CO2)CC1

0.592

View
O=C(NCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)C1=CC=CO1

0.589

View
O=C1CC(CC(=O)N2CCN(C(=O)C3=CC=CO3)CC2)C1

0.589

View
O=C(CCC1=CC=CO1)N1CCN(C(=O)C2=CC=CO2)CC1

0.589

View
O=C(OCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)C1=CC=CO1

0.589

View
O=C(CN1CCCCCCC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.589

View
O=C(CN1CCCCCCCC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.589

View
O=C(CN1CCN(CC(=O)N2CCN(C(=O)C3=CC=CO3)CC2)CC1)N1CCCC1

0.589

View
O=C(CC1=CC=CC=C1Cl)N1CCN(C(=O)C2=CC=CO2)CC1

0.586

View
O=C(NCCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)C1=CC=CO1

0.586

View
O=C(C1=CC=CO1)N1CCN(S(=O)(=O)CCl)CC1

0.585

View
O=C(C1=CC=CO1)N1CCN(C(=O)N2CCC2)CC1

0.580

View
O=C(CC1=C(F)C=CC=C1F)N1CCN(C(=O)C2=CC=CO2)CC1

0.579

View
O=C(COC1=CC=CC=C1)N1CCN(C(=O)C2=CC=CO2)CC1

0.579

View
O=C(CN1CCCC1)N1CCN(CC(=O)N2CCN(C(=O)C3=CC=CO3)CC2)CC1

0.579

View
CCCC(CCC)CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.579

View
O=C(CSCC(=O)N1CCN(C(=O)C2=CC=CO2)CC1)N1CCCCC1

0.579

View
O=C(CC1CCCCCC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.579

View
CC1=CC=CC(C)=C1CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.569

View
O=C(CCC1=C(Cl)C=CC=C1Cl)N1CCN(C(=O)C2=CC=CO2)CC1

0.567

View
O=C(CN1CCN(C(=O)C2=CC=CO2)CC1)N1CCC1

0.564

View
O=C(C1=CC=CO1)N1CCN(C(=O)N2CCCC2)CC1

0.558

View
O=C(COC1=CC=C(Cl)C=C1)N1CCN(C(=O)C2=CC=CO2)CC1

0.557

View
O=C(C1=CC=CO1)N1CCN(C(=O)C2=C(Cl)C=CC=C2Cl)CC1

0.556

View
CC1=CC(C)=C(CC(=O)N2CCN(C(=O)C3=CC=CO3)CC2)C(C)=C1

0.550

View
CC1=CC=CC(Cl)=C1CC(=O)N1CCN(C(=O)C2=CC=CO2)CC1

0.548

View
O=C(CN1CCN(C(=O)C2=CC=CO2)CC1)N1CCCC1

0.544

View
O=C(CCC(=O)N1CCN(C2=CC=CC=C2)CC1)N1CCN(C(=O)C2=CC=CO2)CC1

0.541

View
O=C(CN1CCN(C(=O)C2=CC=CO2)CC1)N1CCCCCC1

0.525

View
O=C(C1=CC=CO1)N1CCN(C(=O)C23CC(F)(C2)C3)CC1

0.509

View
ClCC(=O)N1CCN(CC1)C(=O)c1ccco1

1.000

View
ClCCC(=O)N1CCN(CC1)C(=O)c1ccco1

0.745

View
O=C(N1CCN(CC1)C(=O)c1ccco1)c1ccco1

0.725

View
CCC(=O)N1CCN(CC1)C(=O)c1ccco1

0.702

View
CCCC(=O)N1CCN(CC1)C(=O)c1ccco1

0.660

View
CC(C)CC(=O)N1CCN(CC1)C(=O)c1ccco1

0.647

View
CC(=O)N1CCN(CC1)C(=O)c1ccco1

0.630

View
NC(=O)N1CCN(CC1)C(=O)c1ccco1

0.630

View
CCOCC(=O)N1CCN(CC1)C(=O)c1ccco1

0.623

View
OC(=O)C(=O)N1CCN(CC1)C(=O)c1ccco1

0.604

View
C=CC(=O)N1CCN(CC1)C(=O)c1ccco1

0.592

View
O=C(CNC(=O)c1ccco1)N1CCN(CC1)C(=O)c1ccco1

0.589

View
O=C(N1CCN(Cc2ccccc2)CC1)c1ccco1

0.585

View
CN1CCN(CC1)C(=O)c1ccco1

0.583

View
CCN1CCN(CC1)C(=O)c1ccco1

0.580

View
CN1CCN(CC(=O)N2CCN(CC2)C(=O)c2ccco2)CC1

0.579

View
CCN1CCN(CC(=O)N2CCN(CC2)C(=O)c2ccco2)CC1

0.579

View
CC(Cl)C(=O)N1CCN(CC1)C(=O)c1ccco1

0.577

View
NC(=O)CN1CCN(CC1)C(=O)c1ccco1

0.577

View
Cl.O=C(N1CCN(Cc2ccccc2)CC1)c1ccco1

0.574

View
Cl.CN1CCN(CC1)C(=O)c1ccco1

0.571

View
Cl.CCN1CCN(CC1)C(=O)c1ccco1

0.569

View
O=C(C#C)N1CCN(CC1)C(=O)c1ccco1

0.569

View
CC(C)(C)C(=O)N1CCN(CC1)C(=O)c1ccco1

0.569

View
CC(C)C(=O)N1CCN(CC1)C(=O)c1ccco1

0.569

View
FC(F)(F)C(=O)N1CCN(CC1)C(=O)c1ccco1

0.569

View
CNC(=O)N1CCN(CC1)C(=O)c1ccco1

0.569

View
CN(C)C(=O)N1CCN(CC1)C(=O)c1ccco1

0.569

View
COC(=O)N1CCN(CC1)C(=O)c1ccco1

0.569

View
O=CN1CCN(CC1)C(=O)c1ccco1

0.560

View
OCCN1CCN(CC1)C(=O)c1ccco1

0.558

View
CC(C)(C)CN1CCN(CC1)C(=O)c1ccco1

0.558

View
O=C(N1CCN(CC1)C(=O)c1ccccc1)c1ccco1

0.558

View
O=C(C1CC1)N1CCN(CC1)C(=O)c1ccco1

0.558

View
O=C(N1CCNCC1)c1ccco1

0.551

View
CC(C)N1CCN(CC1)C(=O)c1ccco1

0.549

View
Cl.OCCN1CCN(CC1)C(=O)c1ccco1

0.547

View
C=CCN1CCN(CC1)C(=O)c1ccco1

0.547

View
Cc1ccc(CN2CCN(CC2)C(=O)c2ccco2)cc1

0.544

View
Cl.O=C(N1CCNCC1)c1ccco1

0.540

View
CC#CC(=O)N1CCN(CC1)C(=O)c1ccco1

0.537

View
CC(O)CN1CCN(CC1)C(=O)c1ccco1

0.527

View
Cc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1ccco1

0.527

View
OC(=O)C(O)=O.CC(C)N1CCN(CC1)C(=O)c1ccco1

0.519

View
O=C(N1CCN(Cc2ccco2)CC1)c1ccco1

0.518

View
CN(C)CCN1CCN(CC1)C(=O)c1ccco1

0.518

View
O=C(N1CCN(CCN2CCOCC2)CC1)c1ccco1

0.518

View
CC(C)(C)NC(=O)CN1CCN(CC(=O)N2CCN(CC2)C(=O)c2ccco2)CC1

0.508

View
OC(=O)C(O)=O.CCC(C)N1CCN(CC1)C(=O)c1ccco1

0.500

View
COC(CN1CCN(CC1)C(=O)c1ccco1)OC

0.500

View
O=C(N1CCN(CC1)C1CCCC1)c1ccco1

0.500

View
CCC(O)CN1CCN(CC1)C(=O)c1ccco1

0.500

View
O=C(NCCN1CCN(CC1)C(=O)c1ccco1)c1ccco1

0.492

View
O=C(CN1CCN(CC1)C(=O)c1ccco1)NCc1ccco1

0.484

View
Cl.ClCC(=O)N1CCN(Cc2ccco2)CC1

0.474

View
O=C(CN1CCN(CC1)C(=O)c1ccco1)NC1CC1

0.468

View
O=C(N1CCNC(=O)C1)c1ccco1

0.464

View
CCN1CCN(CC1)C(=O)C(C)N1CCN(CC1)C(=O)c1ccco1

0.446

View
O=C(N1CC(=O)NC(=O)C1)c1ccco1

0.426

View
CC1CN(CCN1C(=O)c1ccco1)C(=O)c1ccco1

0.417

View
CC1CN(C(C)CN1C(=O)c1ccco1)C(=O)c1ccco1

0.364

View
Cc1ccc(o1)C(=O)N1CCN(CC1)C(=O)c1ccc(C)o1

0.340

View
O=C(NCCNC(=O)c1ccco1)c1ccco1

0.327

View
Cl.O=C(NCCN1CCCC1)c1ccco1

0.317

View
O=C(NCCN1CCCCC1)c1ccco1

0.308

View
O=C(NCCN1CCNCC1)c1ccco1

0.303

View
CCN1CCN(CC1)C(=O)c1ccc(C)o1

0.290

View
Cc1ccc(o1)C(=O)N1CCN(CC(Cl)=C)CC1

0.284

View
CC(C)N(C)CCNC(=O)c1ccco1

0.281

View
CCC(=O)NCCNC(=O)c1ccco1

0.274

View
Cl.OCCNCCNC(=O)c1ccco1

0.270

View
Cc1ccc(o1)C(=O)NCCN1CCN(CC1)C(=O)c1ccc(C)o1

0.260

View
Cl.Cc1ccc(o1)C(=O)N1CCNCC1

0.254

View
[#6]\[#6](-[#6])=[#6]/[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-[#7]-[#6](=O)-c2ccco2)-[#6]-[#6]-1

0.250

View
C(N1CCN(C(=O)C2OC=CC=2)CC1)(=O)CC

0.702

View
C(N1CCN(C(=O)C2OC=CC=2)CC1)(=O)CSC

0.673

View
C(N1CCN(C(=O)C2OC=CC=2)CC1)(=O)CC=C

0.660

View
C(N1CCN(C(=O)C2OC=CC=2)CC1)(=O)CN(C)C

0.647

View
C(N1CCN(C(=O)C2OC=CC=2)CC1)(=O)COC

0.647

View
C(N1CCN(C(C)=O)CC1)(=O)C1OC=CC=1

0.630

View
C(N1CCN(C(=O)C2OC=CC=2)CC1)(C(Cl)Cl)=O

0.600

View
C(N1CCN(C)CC1)(=O)C1OC=CC=1

0.583

View
C(N1CCN(CC)CC1)(=O)C1OC=CC=1

0.580

View
N1(CC(N)=O)CCN(C(=O)C2OC=CC=2)CC1

0.577

View
N1(CC(Cl)Cl)CCN(C(=O)C2OC=CC=2)CC1

0.566

View
C(N1CCN(C=O)CC1)(C1OC=CC=1)=O

0.560

View
C(N1CCN(C(C)C)CC1)(=O)C1OC=CC=1

0.549

View
N1(CC=O)CCN(C(=O)C2OC=CC=2)CC1

0.547

View
C(N1CCN(CCC)CC1)(=O)C1OC=CC=1

0.547

View
C(N1CCN(CC=C)CC1)(=O)C1OC=CC=1

0.547

View
N1(CCF)CCN(C(=O)C2OC=CC=2)CC1

0.547

View
N1(CCN(C)C)CCN(C(=O)C2OC=CC=2)CC1

0.518

View
N1(CCN(CC)CC)CCN(C(=O)C2OC=CC=2)CC1

0.517

View
C(N1CCN(C(C)=O)CC1)(=O)C1OC(Cl)=CC=1

0.333

View

Discussion: