Molecule Details

N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1
piperazine-chloroacetamide Enamine Assayed
Molecular Properties
SMILES:
N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1
MW: 277.1
Fraction sp3: 0.43
HBA: 3
HBD: 0
Rotatable Bonds: 3
TPSA: 47.34
cLogP: 1.44
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine SCR: Z4450620211
Activity Data
IC50 (µM) - Fluorescence: 19.6916117921927
IC50 (µM) - RapidFire: 12.2462267635219
pIC50 (µM) - Fluorescence 4.7057187346589
Average Inhibition @ 20 µM - Fluorescence: 53.37036
Average Inhibition @ 50 µM - Fluorescence: 85.20008
Average Inhibition @ 20 µM - RapidFire: 64.3036339317386
Relative Solubility @ 20 µM: 1.01
Relative Solubility @ 100 µM: 0.99
Order Status
Shipped: 2020-05-20

CC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

PAT-UNK-b2d83456-1
0.714

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15
0.649

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

AAR-POS-d2a4d1df-35
0.649

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.610

View
N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-6ca90168-14
0.603

View
N#Cc1ncc(CCc2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-9
0.586

View
CN(C)Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

JOK-SYG-18591e8f-1
0.571

View
N#Cc1ncc(-c2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-7
0.571

View
O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.544

View
CN(c1cnc(C#N)nc1)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-849bee6c-14
0.541

View
N#Cc1nccc(-c2cccc(CN3CCN(C(=O)CCl)CC3)c2)n1

MAK-UNK-849bee6c-6
0.539

View
N#Cc1cccc(CC2CCN(C(=O)CCl)CC2)c1

MAK-UNK-10dfa458-40
0.537

View
N#Cc1ncc(Sc2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-16
0.526

View
N#Cc1ncc(Nc2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-4
0.526

View
N#Cc1ncc(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-12
0.526

View
N#Cc1ncccc1-c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-849bee6c-5
0.519

View
N#Cc1nccc(CCc2cccc(CN3CCN(C(=O)CCl)CC3)c2)n1

MAK-UNK-849bee6c-8
0.519

View
CC(=O)Nc1cc(C#N)cc(CN2CCN(C(=O)CCl)CC2)c1

TAM-UNI-d1c3dd9f-16
0.514

View
C=C(Cc1ccno1)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

SEA-TRI-f93fcab4-1
0.513

View
CC(C)C[C@@H]1CN(C(=O)CCl)CCN1Cc1cccc(C#N)c1

SAD-SAT-c989feaa-2
0.506

View
N#Cc1cccc(CN2CCN(C(=O)c3cc(=O)[nH]c4ccccc34)CC2)c1

ERI-UCB-a0b0dbcb-14
0.506

View
CC(=O)Nc1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-18
0.500

View
N#Cc1nccc(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)n1

MAK-UNK-849bee6c-13
0.494

View
N#Cc1nccc(Nc2cccc(CN3CCN(C(=O)CCl)CC3)c2)n1

MAK-UNK-849bee6c-3
0.494

View
N#Cc1nccc(Sc2cccc(CN3CCN(C(=O)CCl)CC3)c2)n1

MAK-UNK-849bee6c-17
0.494

View
CCNc1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-3
0.493

View
CN(c1cccc(CN2CCN(C(=O)CCl)CC2)c1)c1ccnc(C#N)n1

MAK-UNK-849bee6c-15
0.488

View
N#Cc1cc(CN2CCN(C(=O)CCl)CC2)c2ccccc2c1

DAR-DIA-fb20be43-6
0.486

View
CC#Cc1cccc(CN2CCN(C(C)=O)CC2)c1

PAT-UNK-b2d83456-2
0.485

View
O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.483

View
CNCCSC(=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-176ca439-3
0.480

View
CNCCSC(=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-cd94b63c-1
0.480

View
CNC(=O)c1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-17
0.479

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.475

View
O=C(CCl)N1CCN(Cc2cccc(CNC(=O)N3CCOCC3)c2)CC1

TAM-UNI-d1c3dd9f-12
0.474

View
COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1F

SAD-SAT-5b1897b2-5
0.471

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAR-TRE-6a44bbf2-54
0.471

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAK-UNK-7c9d1431-16
0.471

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCO3)CC1

MAK-UNK-7c9d1431-14
0.471

View
N#COC1CCCC(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)C1

MAK-UNK-10dfa458-45
0.470

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

LON-WEI-8f408cad-7
0.460

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

MAK-UNK-212f693e-8
0.460

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

AAR-POS-0daf6b7e-13
0.460

View
CCNC(COc1cccc(CN2CCN(C(=O)CCl)CC2)c1)OCC#N

MAK-UNK-af83ef51-20
0.459

View
N#Cc1cccc(CN2CCN(S(=O)(=O)/C=C/CN3CCC3=O)CC2)c1

SEA-TRI-ec70a9dd-1
0.456

View
N#Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-987948f6-3
0.453

View
N#Cc1ccsc1CN1CCN(C(=O)CCl)CC1

DAV-CRI-d1e0885a-1
0.449

View
NS(=O)(=O)c1ccc2cc(CN3CCN(C(=O)CCl)CC3)ccc2c1

SEL-UNI-cd366922-7
0.446

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-4
0.446

View
N#Cc1cccc(C(c2ccccc2)N2CCN(C(=O)CCl)CC2)c1

DAR-DIA-3e9bbd81-11
0.446

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

PAU-UNI-52c0427f-1
0.446

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

BRU-LEF-ae0885ba-1
0.446

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)CCO3)CC1

MAK-UNK-7c9d1431-18
0.444

View
CNC(=O)C(NCCNC(C)=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-176ca439-2
0.444

View
O=C(CCl)N1CCN(Cc2cc(F)cc(Cl)c2)CC1

SAD-SAT-581007d4-1
0.439

View
Cc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-2
0.439

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

MAT-POS-2db6411e-2
0.439

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

SAD-SAT-581007d4-7
0.439

View
O=C(CCl)N1CCN(Cc2ccc(CS(=O)(=O)F)cc2)CC1

JIA-UNI-93b03cae-1
0.439

View
COC1CCCC(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)C1

MAK-UNK-3c359d2a-1
0.439

View
O=C(CSCc1cccc(CN2CCN(C(=O)CCl)CC2)c1)CN1CCC(O)CC1

MAK-UNK-e4a48a85-7
0.439

View
COC1CCCC(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)C1

MAK-UNK-176ca439-4
0.439

View
CCNC1CC(c2cccc(CN3CCN(C(=O)CCl)CC3)c2)CC(O)C1OC#N

MAK-UNK-af83ef51-21
0.438

View
CCNc1cccc(C#N)c1CN1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-24
0.434

View
C=CC(=O)N1CCN(Cc2cccc(Cl)c2)CC1

MAK-UNK-6ca90168-13
0.433

View
N#Cc1cccc(C(CCc2ccccc2)N2CCN(C(=O)CCl)CC2)c1

PAU-WEI-b9b69149-4
0.432

View
O=C(CCl)N1CCN(Cc2cccs2)CC1

AAR-POS-0daf6b7e-17
0.431

View
O=C(CCl)N1CCN(Cc2cccs2)CC1

LON-WEI-8f408cad-5
0.431

View
O=C(CCl)N1CCN(Cc2ccco2)CC1

MAK-UNK-7c9d1431-28
0.431

View
O=C(CCl)N1CCN(Cc2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-2
0.431

View
CCNC1CC(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)CCC1OC#N

MAK-UNK-af83ef51-19
0.429

View
O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

MED-COV-4280ac29-31
0.423

View
O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

AAR-POS-d2a4d1df-40
0.423

View
CCNc1ccc(Nc2cc(C#N)cc(CN3CCN(C(=O)CCl)CC3)c2)c(C#N)c1

MAK-UNK-10dfa458-44
0.420

View
O=C(CCl)N1CCN(Cc2c(F)cccc2Cl)CC1

AHN-SAT-de2502ba-15
0.420

View
Cc1ccc(CN2CCCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-21
0.420

View
N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1C(=O)N1CCC(O)CC1

MAK-UNK-10dfa458-38
0.420

View
O=C(CCl)N1CCN(Cc2cn(Cc3ccccc3)nn2)CC1

STE-KUL-2e0d2e88-7
0.419

View
N#Cc1ccc(-c2cc(CN3CCN(C(=O)CCl)CC3)cc3cnccc23)cc1

FAB-UNK-7ad5ab26-2
0.419

View
Cc1ccccc1CN1CCN(C(=O)CCl)CC1

MAK-UNK-7c9d1431-20
0.418

View
O=C(CCl)N1CCN(Cc2cnc(-c3ccccc3)nc2)CC1

MAK-UNK-af83ef51-1
0.417

View
N#Cc1cccc(CC2CC3CCC(C2)N3C(=O)CCl)c1

MAK-UNK-10dfa458-41
0.413

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

DAR-DIA-fb20be43-8
0.413

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

PAU-UNI-19862c28-1
0.413

View
N#Cc1ccc(CNC(=O)N2CCOCC2)c(CN2CCN(C(=O)CCl)CC2)c1

TAM-UNI-d1c3dd9f-1
0.412

View
N#Cc1ccc(CNC(=O)N2CCOCC2)c(CN2CCN(C(=O)CCl)CC2)c1

DAR-DIA-fb20be43-16
0.412

View
O=C(CCl)N1CCN(Cc2cc(O)ccc2O)CC1

NEH-REV-107bcf72-5
0.412

View
O=C(CCl)N1CCN(C(=O)c2cccc(Cl)c2)CC1

MAK-UNK-6ca90168-15
0.409

View
N#Cc1cccc(NC2CCN(C(=O)CCl)C2)c1

TAT-ENA-80bfd3e5-10
0.408

View
NC(=O)CCCCC(=O)N1CCN(Cc2cccc(F)c2)CC1

VIT-UNK-2a0afa28-3
0.405

View
CS(=O)(=O)N1CCc2ccc(CN3CCN(C(=O)CCl)CC3)cc2C1

TAM-UNI-d1c3dd9f-5
0.405

View
CNS(=O)(=O)c1ccc2ccc(CN3CCN(C(=O)CCl)CC3)cc2c1

TAM-UNI-d1c3dd9f-6
0.405

View
Cc1ccc(CN2CCN(C(=O)CCl)CC2)o1

MAR-LAB-ca4662a6-2
0.403

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-23
0.403

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

AAR-POS-0daf6b7e-12
0.403

View
COCc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

MED-COV-4280ac29-33
0.403

View
NS(=O)(=O)c1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-3
0.403

View
Cc1cc(CN2CCN(C(=O)CCl)CC2)cc(S(N)(=O)=O)c1

SAD-SAT-581007d4-4
0.403

View
CC(=O)NCCc1cccc(CN2CCN(C(C)=O)CC2)c1

WIL-LEE-23e8b574-3
0.403

View
N#Cc1cnc(CCO)cc1CN1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-35
0.403

View
CCC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.762

View
N#Cc1cccc(CN2CCN(C(=O)CO)CC2)c1

0.762

View
N#Cc1cccc(CN2CCN(C(=O)Cc3ccccc3)CC2)c1

0.744

View
N#Cc1cccc(CN2CCN(C(=O)CN3CCCC3)CC2)c1

0.744

View
N#Cc1cccc(CN2CCN(C(=O)Cc3cccc(Cl)c3)CC2)c1

0.733

View
N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

0.732

View
CN(C)CC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.727

View
N#Cc1cccc(CN2CCN(CC(=O)N3CCCC3)CC2)c1

0.721

View
N#Cc1cccc(CN2CCN(C(=O)Cc3ccc(Cl)cc3)CC2)c1

0.717

View
N#Cc1cccc(CN2CCN(C(=O)N3CCCC3)CC2)c1

0.714

View
N#Cc1cccc(CN2CCN(C(=O)C(=O)N3CCCC3)CC2)c1

0.714

View
CC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.714

View
COCC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.711

View
CC(C)CC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.711

View
N#Cc1cccc(CN2CCN(C(=O)Cc3cccc(F)c3)CC2)c1

0.711

View
N#Cc1cccc(CN2CCN(C(=O)c3c(Cl)cccc3Cl)CC2)c1

0.711

View
N#Cc1cccc(CN2CCN(CC(=O)N3CCCCCC3)CC2)c1

0.705

View
N#Cc1cccc(CN2CCN(CC(=O)N3CCCCC3)CC2)c1

0.705

View
N#Cc1cccc(CN2CCN(C(=O)N3CCCCC3)CC2)c1

0.698

View
CCC(=O)N1CCCN(Cc2cccc(C#N)c2)CC1

0.696

View
N#Cc1cccc(CN2CCCN(CC(=O)N3CCCC3)CC2)c1

0.689

View
N#Cc1cccc(CN2CCN(C(=O)Cc3ccccc3Cl)CC2)c1

0.688

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

0.683

View
N#Cc1cccc(CN2CCN(C(=O)CN3CCOCC3)CC2)c1

0.681

View
N#Cc1cccc(CN2CCN(C(=O)CN3C(=O)CCC3=O)CC2)c1

0.681

View
N#Cc1cccc(CN2CCN(C(=O)CCCc3ccccc3)CC2)c1

0.681

View
Cc1ccc(CC(=O)N2CCN(Cc3cccc(C#N)c3)CC2)cc1

0.681

View
CCN(CC)CC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.681

View
N#Cc1cccc(CN2CCN(Cc3cccc(C#N)c3)CC2)c1

0.676

View
N#Cc1cccc(CN2CCN(C(=O)COc3ccc(F)cc3)CC2)c1

0.673

View
CC(C)(C)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.667

View
N#Cc1cccc(CN2CCN(C(=O)Cc3cccs3)CC2)c1

0.667

View
CC(C)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.667

View
COC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.667

View
N#Cc1cccc(CN2CCN(C(=O)Cc3ccccc3F)CC2)c1

0.667

View
N#Cc1cccc(CN2CCN(C(=O)CC3CCCCC3)CC2)c1

0.667

View
CN(C)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.667

View
N#Cc1cccc(CN2CCN(C(=O)c3ccccc3)CC2)c1

0.667

View
N#Cc1cccc(CN2CCN(C(=O)C3CC3)CC2)c1

0.667

View
CNC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.667

View
N#Cc1ccc(CN2CCCN(C(=O)CCl)CC2)cc1

0.667

View
N#Cc1cccc(CN2CCN(C(=O)N3CCNCC3)CC2)c1

0.667

View
Cc1ccc(OCC(=O)N2CCN(Cc3cccc(C#N)c3)CC2)cc1

0.660

View
N#Cc1cccc(CN2CCN(C(=O)COc3ccc(Br)cc3)CC2)c1

0.660

View
N#Cc1cccc(CN2CCN(C(=O)c3cccs3)CC2)c1

0.660

View
N#Cc1cccc(CN2CCN(C(=O)c3cc(Cl)cc(Cl)c3)CC2)c1

0.660

View
N#Cc1cccc(CN2CCN(C(=O)c3ccc(Cl)cc3)CC2)c1

0.660

View
N#Cc1cccc(CN2CCN(C(=O)CCC3CCCC3)CC2)c1

0.653

View
N#Cc1cccc(CN2CCCN(C(=O)CCc3ccccc3)CC2)c1

0.653

View
COc1cccc(CC(=O)N2CCN(Cc3cccc(C#N)c3)CC2)c1

0.653

View
N#Cc1cccc(CN2CCCN(C(=O)Cc3cccc(F)c3)CC2)c1

0.653

View
CC(C)CC(=O)N1CCCN(Cc2cccc(C#N)c2)CC1

0.653

View
N#Cc1cccc(CN2CCN(C(=O)N3CCOCC3)CC2)c1

0.652

View
N#Cc1cccc(CN2CCN(C(=O)C(=O)N3CCOCC3)CC2)c1

0.652

View
CC(=O)N1CCCN(Cc2cccc(C#N)c2)CC1

0.652

View
CCN(CC)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.652

View
N#Cc1cccc(CN2CCN(C(=O)c3c(F)cccc3F)CC2)c1

0.652

View
N#Cc1cccc(CN2CCCN(C(N)=O)CC2)c1

0.652

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

0.651

View
O=C(CCl)N1CCN(Cc2cccc(O)c2)CC1

0.651

View
N#Cc1cccc(CN2CCN(C(=O)c3cccc(Cl)c3)CC2)c1

0.646

View
N#Cc1cccc(CN2CCN(C(=O)CCC3CCCCC3)CC2)c1

0.640

View
N#Cc1cccc(CN2CCCN(C(=O)CC3CCCC3)CC2)c1

0.640

View
CCOC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.638

View
CCNC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.638

View
CC(O)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.638

View
CCC(CC)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.638

View
N#Cc1cccc(CN2CCN(C(=O)Oc3ccccc3)CC2)c1

0.638

View
N#Cc1cccc(CN2CCN(C(=O)c3ccc(F)cc3)CC2)c1

0.638

View
N#Cc1cccc(CN2CCN(CC(N)=O)CC2)c1

0.636

View
N#Cc1cccc(CN2CCN(CC(=O)O)CC2)c1

0.636

View
CN(CC(=O)N1CCN(Cc2cccc(Cl)c2)CC1)Cc1cccc(C#N)c1

0.635

View
N#Cc1cccc(CN2CCN(Cc3cccc(Cl)c3)CC2)c1

0.634

View
N#Cc1cccc(CN2CCN(C(=O)c3ccc(Cl)cc3Cl)CC2)c1

0.633

View
N#Cc1cccc(CN2CCN(C(=O)c3cccc(Cl)c3Cl)CC2)c1

0.633

View
O=C(CCl)N1CCN(Cc2cccc([N+](=O)[O-])c2)CC1

0.630

View
N#Cc1cccc(OCC(=O)N2CCN(Cc3cccc(Cl)c3)CC2)c1

0.627

View
N#Cc1cccc(SCC(=O)N2CCN(Cc3cccc(Cl)c3)CC2)c1

0.627

View
CN(CC(=O)N1CCN(Cc2ccccc2)CC1)Cc1cccc(C#N)c1

0.627

View
Cc1cc(C)cc(OCC(=O)N2CCN(Cc3cccc(C#N)c3)CC2)c1

0.627

View
CC(=O)NCC(=O)N1CCCN(Cc2cccc(C#N)c2)CC1

0.627

View
N#Cc1cccc(CN2CCN(C(=O)Cn3cnnn3)CC2)c1

0.627

View
CCC(=O)N1CCN(Cc2cccc(OCc3cccc(C#N)c3)c2)CC1

0.627

View
CCN1CCN(C(=O)CC2CCN(Cc3cccc(C#N)c3)CC2)CC1

0.627

View
N#Cc1cccc(COc2cccc(CN3CCN(C(=O)CO)CC3)c2)c1

0.627

View
N#Cc1cccc(C(=O)N2CCN(Cc3cccc(Cl)c3)CC2)c1

0.625

View
N#Cc1ccc(CC(=O)N2CCN(Cc3cccc(Cl)c3)CC2)cc1

0.625

View
N#Cc1cccc(CN2CCCN(Cc3cccc(C#N)c3)CC2)c1

0.625

View
CC(C)(C)OC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.625

View
N#Cc1cccc(CN2CCN(C(=O)OCc3ccccc3)CC2)c1

0.625

View
N#Cc1cccc(CN2CCN(C(=O)c3ccc(O)cc3)CC2)c1

0.625

View
N#Cc1cccc(CN2CCC(CC(=O)N3CCCC3)CC2)c1

0.625

View
Cc1ccc(C(=O)N2CCN(Cc3cccc(C#N)c3)CC2)cc1

0.625

View
N#Cc1cccc(CN2CCN(C(=O)c3ccc(Br)cc3)CC2)c1

0.625

View
N#Cc1cccc(CN2CCN(C(=O)c3cccc(F)c3)CC2)c1

0.625

View
N#Cc1cccc(CN2CCN(C(=O)c3ccccc3F)CC2)c1

0.625

View
CC(C)(C)NC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.625

View
COC(OC)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.625

View
O=C(CCl)N1CCN(Cc2cccc(C(F)(F)F)c2)CC1

0.622

View
COc1cccc(CN2CCN(C(=O)CCl)CC2)c1

0.622

View
CC(Cl)C(=O)N1CCN(C(C)c2cccc(C#N)c2)CC1

0.197

View
O=C(CCl)N1CCN(Cc2ccccc2)CC1

0.196

View
Cl.O=C(CCl)N1CCN(Cc2ccccc2)CC1

0.196

View
CC(=O)N1CCN(C(=O)c2cccc(C#N)c2)CC1

0.190

View
N#CCC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.190

View
N#Cc1cccc(C(=O)N2CCN(Cc3ccccc3)CC2)c1

0.183

View
CN1CCN(C(=O)c2cccc(C#N)c2)CC1

0.183

View
CC(C)C(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.183

View
Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1C

0.165

View
CC(=O)N1CCN(C(=O)CN(C)Cc2cccc(C#N)c2)CC1

0.161

View
N#Cc1cccc(CN2CCN(C(=O)c3ccccc3)CC2)c1

0.153

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

0.108

View
CC(=O)N1CCN(Cc2cccc(C#N)c2)CC1

0.078

View
N1(CC2C=CC=C(C#N)C=2)CCN(C(C)=O)CC1

0.939

View
N1(CC2C=CC=C(C#N)C=2)CCN(C=O)CC1

0.888

View
N1(CC2C=CC=C(C)C=2)CCN(C(C)=O)CC1

0.878

View
C(N1CCN(CC2C=CC=C(C)C=2)CC1)(=O)C(Cl)Cl

0.860

View
N(CC1C=CC=C(C#N)C=1)(C)CC(N1CCN(C)CC1)=O

0.853

View


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