Molecule Details

COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1F
piperazine-chloroacetamide Enamine Mcule MolPort
Molecular Properties
SMILES:
COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1F
MW: 300.1
Fraction sp3: 0.5
HBA: 3
HBD: 0
Rotatable Bonds: 4
TPSA: 32.78
cLogP: 1.72
Covalent Warhead: ✔️
Covalent Fragment: ✔️
Source
Enamine SCR: Z1562119860
Enamine REAL: Z1562119860
Mcule: MCULE-4671351786
MolPort: MolPort-005-310-681
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24

View

O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.534

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.532

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O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

AAR-POS-d2a4d1df-35
0.516

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15
0.516

View
CN(C)Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

JOK-SYG-18591e8f-1
0.500

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAK-UNK-7c9d1431-16
0.493

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCO3)CC1

MAK-UNK-7c9d1431-14
0.493

View
COc1cc(C)c(CN2CCN(C(=O)CCl)CC2)cc1OC

SAD-SAT-65574d3f-10
0.493

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAR-TRE-6a44bbf2-54
0.493

View
O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.492

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)CCO3)CC1

MAK-UNK-7c9d1431-18
0.486

View
O=C(CCl)N1CCN(Cc2cc(F)cc(Cl)c2)CC1

SAD-SAT-581007d4-1
0.484

View
O=C(CCl)N1CCN(Cc2ccc(CS(=O)(=O)F)cc2)CC1

JIA-UNI-93b03cae-1
0.484

View
N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-6ca90168-14
0.476

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.475

View
N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAT-POS-ee51dedd-1
0.471

View
COCc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

MED-COV-4280ac29-33
0.464

View
Cc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-2
0.462

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

MAK-UNK-212f693e-8
0.460

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

LON-WEI-8f408cad-7
0.460

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

AAR-POS-0daf6b7e-13
0.460

View
COCCc1ccc(Cl)cc1CN1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-37
0.452

View
NS(=O)(=O)c1ccc2cc(CN3CCN(C(=O)CCl)CC3)ccc2c1

SEL-UNI-cd366922-7
0.446

View
CS(=O)(=O)N1CCc2ccc(CN3CCN(C(=O)CCl)CC3)cc2C1

TAM-UNI-d1c3dd9f-5
0.442

View
CNS(=O)(=O)c1ccc2ccc(CN3CCN(C(=O)CCl)CC3)cc2c1

TAM-UNI-d1c3dd9f-6
0.442

View
Cc1ccc(CN2CCCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-21
0.441

View
O=C(CCl)N1CCN(Cc2c(F)cccc2Cl)CC1

AHN-SAT-de2502ba-15
0.441

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

MAT-POS-2db6411e-2
0.439

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

SAD-SAT-581007d4-7
0.439

View
O=C(CCl)N1CCN(Cc2cc(O)ccc2O)CC1

NEH-REV-107bcf72-5
0.433

View
O=C(CCl)N1CCN(Cc2cccs2)CC1

LON-WEI-8f408cad-5
0.431

View
O=C(CCl)N1CCN(Cc2cccs2)CC1

AAR-POS-0daf6b7e-17
0.431

View
N#Cc1ncc(-c2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-7
0.429

View
COC(=O)C(NS(=O)(=O)NS(N)(=O)=O)c1ccc(CN2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-af83ef51-14
0.429

View
CN(c1cnc(C#N)nc1)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-849bee6c-14
0.425

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

AAR-POS-0daf6b7e-12
0.424

View
Cc1ccc(CN2CCN(C(=O)CCl)CC2)o1

MAR-LAB-ca4662a6-2
0.424

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-23
0.424

View
CNCCSC(=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-176ca439-3
0.423

View
CNCCSC(=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-cd94b63c-1
0.423

View
Cc1cc(CN2CCN(C(=O)CCl)CC2)cc(S(N)(=O)=O)c1

SAD-SAT-581007d4-4
0.423

View
COC1CCCC(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)C1

MAK-UNK-176ca439-4
0.422

View
COC1CCCC(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)C1

MAK-UNK-3c359d2a-1
0.422

View
O=C(CCl)N1CCN(Cc2cc(F)cc3ccccc23)CC1

DAR-DIA-fb20be43-2
0.419

View
Cc1ccccc1CN1CCN(C(=O)CCl)CC1

MAK-UNK-7c9d1431-20
0.418

View
COc1ccccc1-n1cc(CN2CCN(C(=O)CCl)CC2)nn1

ANT-STE-dbb91f63-3
0.418

View
COc1cc(CN2CCN(C(=O)CCl)CC2)c2ccccc2c1

DAR-DIA-fb20be43-7
0.416

View
Cc1nc(CN2CCN(C(=O)CCl)CC2)cs1

SAD-SAT-5b1897b2-2
0.412

View
CNC(=O)C(NCCNC(C)=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-176ca439-2
0.410

View
O=C(CCl)N1CCN(Cc2ccco2)CC1

MAK-UNK-7c9d1431-28
0.409

View
O=C(CCl)N1CCN(Cc2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-2
0.409

View
COCc1cc(CN2CCN(C(=O)CCl)CC2)sc1Br

JOH-UNI-27ac80fd-38
0.405

View
N#Cc1ncc(CCc2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-9
0.405

View
CC(=O)NCCc1cn(C)c2cc(CN3CCN(C(=O)CCl)CC3)ccc12

TAM-UNI-d1c3dd9f-19
0.405

View
CN(C)c1cc(F)c(N2CCN(C(=O)CCl)CC2)c(F)c1

NIM-UNI-310206f0-6
0.403

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1OC

MAK-UNK-7c9d1431-19
0.403

View
NS(=O)(=O)c1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-3
0.403

View
CCNc1ncc(F)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-1
0.403

View
O=C(CCl)N1CCN(Cc2cccc(CNC(=O)N3CCOCC3)c2)CC1

TAM-UNI-d1c3dd9f-12
0.400

View
N#Cc1ncc(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-12
0.398

View
COc1ccc(-n2cc(CN3CCN(C(=O)CCl)CC3)nn2)cc1

ANT-STE-dbb91f63-1
0.397

View
CCNc1ncc(OC)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-5
0.397

View
CCNc1ccccc1CN1CCN(C(=O)CCl)CC1

SEL-UNI-cd366922-6
0.397

View
O=C(CCl)N1CCN(Cc2cnc(-c3ccccc3)nc2)CC1

MAK-UNK-af83ef51-1
0.397

View
CC(=O)NCCC1=CNc2cc(CN3CCN(C(=O)CCl)CC3)ccc2C1

SEL-UNI-cd366922-8
0.395

View
CC(=O)Nc1cc(C#N)cc(CN2CCN(C(=O)CCl)CC2)c1

TAM-UNI-d1c3dd9f-16
0.395

View
CCNC(COc1cccc(CN2CCN(C(=O)CCl)CC2)c1)OCC#N

MAK-UNK-af83ef51-20
0.393

View
NS(=O)(=O)CCc1ccccc1CN1CCN(C(=O)CCl)CC1

MIH-UNI-e573136b-5
0.392

View
Cc1cc(CN2CCN(C(=O)CCl)CC2)ccc1NCCNCN1CCC(O)CC1

MAK-UNK-e4a48a85-18
0.391

View
COc1cccc(-n2cc(CN3CCN(C(=O)CCl)CC3)nn2)c1

ANT-STE-dbb91f63-2
0.390

View
Cc1cc(-c2ccc(CN3CCN(C(=O)COC(F)(F)F)CC3)cc2F)ncn1

BEN-VAN-c986b20b-18
0.388

View
O=C(CCl)N1CCN(Cc2cc(Cl)ccc2CNS(=O)(=O)N2CCOCC2)CC1

STU-CHA-6d5cfe2b-1
0.388

View
O=C(CCl)N1CCN(Cc2cscc2Cl)CC1

SAD-SAT-bc31ec01-1
0.388

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-30
0.387

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-45
0.387

View
CN(c1cccc(CN2CCN(C(=O)CCl)CC2)c1)c1ccnc(C#N)n1

MAK-UNK-849bee6c-15
0.386

View
COCCc1cc(Br)sc1CN1CCN(C(=O)CCl)CC1

JOH-UNI-27ac80fd-39
0.385

View
CNC(=O)c1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-17
0.385

View
NS(=O)(=O)c1ccc2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc2c1

DAR-DIA-fb20be43-12
0.383

View
O=C(CCl)N1CCN(Cc2cn(Cc3ccccc3)nn2)CC1

STE-KUL-2e0d2e88-7
0.382

View
N#Cc1ncc(Nc2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-4
0.381

View
N#Cc1ncc(Sc2cccc(CN3CCN(C(=O)CCl)CC3)c2)cn1

MAK-UNK-849bee6c-16
0.381

View
O=C(CCl)N1CCN(Cc2cc(Cl)ccc2CNC(=O)N2CCOCC2)CC1

STU-CHA-6cae54d3-1
0.381

View
CCNc1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-3
0.380

View
O=C(CCl)N1CCN(c2c(F)cc(-c3ccncc3)cc2F)CC1

NIM-UNI-310206f0-1
0.378

View
CN(C)C(=O)c1ccc(CNS(C)(=O)=O)c(CN2CCN(C(=O)CCl)CC2)c1

TAM-UNI-d1c3dd9f-4
0.378

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

PAU-UNI-19862c28-1
0.377

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

DAR-DIA-fb20be43-8
0.377

View
N#Cc1nccc(-c2cccc(CN3CCN(C(=O)CCl)CC3)c2)n1

MAK-UNK-849bee6c-6
0.376

View
N#Cc1ncccc1-c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-849bee6c-5
0.376

View
N#Cc1nccc(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)n1

MAK-UNK-849bee6c-13
0.375

View
N#Cc1nccc(Sc2cccc(CN3CCN(C(=O)CCl)CC3)c2)n1

MAK-UNK-849bee6c-17
0.375

View
COc1ccc(N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-0daf6b7e-18
0.373

View
O=C(CSCc1cccc(CN2CCN(C(=O)CCl)CC2)c1)CN1CCC(O)CC1

MAK-UNK-e4a48a85-7
0.372

View
Nc1csc(O)c1CN1CCN(C(=O)CCl)CC1

ASH-SAT-43770c7d-5
0.371

View
N#COC1CCCC(Oc2cccc(CN3CCN(C(=O)CCl)CC3)c2)C1

MAK-UNK-10dfa458-45
0.371

View
N#Cc1ccsc1CN1CCN(C(=O)CCl)CC1

DAV-CRI-d1e0885a-1
0.370

View
O=C(CCl)N1CCN(Cc2cc(O)cc3c2OCO3)CC1

NEH-REV-107bcf72-3
0.368

View
O=C(CCl)N1CCN(Cc2scc3ccccc23)CC1

PAU-UNI-b2b6b158-1
0.368

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1C

ASH-SAT-43770c7d-10
0.368

View
COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1F

1.000

View
COc1ccc(CC(=O)N2CCN(Cc3ccc(OC)c(F)c3)CC2)cc1F

0.805

View
COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1OC

0.805

View
CCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.786

View
COc1ccc(CN2CCN(C(=O)CN)CC2)cc1F

0.786

View
COCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.767

View
COc1ccc(CN2CCN(C(=O)CO)CC2)cc1F

0.767

View
COc1ccc(CN2CCN(C(=O)Cc3c(Cl)cccc3Cl)CC2)cc1F

0.761

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(Cl)cc3)CC2)cc1F

0.756

View
COc1ccc(CC(=O)N2CCN(Cc3ccc(OC)c(OC)c3)CC2)cc1F

0.750

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(F)cc3)CC2)cc1F

0.750

View
COc1ccc(CCC(=O)N2CCN(Cc3ccc(OC)c(F)c3)CC2)cc1F

0.750

View
COc1ccc(CN2CCN(C(=O)CN(C)C)CC2)cc1F

0.750

View
CCCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.750

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(OC)c(OC)c3)CC2)cc1F

0.750

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(F)c(F)c3)CC2)cc1F

0.750

View
COc1ccc(CC(=O)N2CCN(Cc3ccc(Cl)cc3)CC2)cc1F

0.739

View
COc1ccc(CN2CCN(C(=O)COC(C)(C)C)CC2)cc1F

0.739

View
COc1ccc(CN2CCN(C(=O)Cc3c(OC)cccc3OC)CC2)cc1F

0.739

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(Cl)c(OC)c3)CC2)cc1F

0.739

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(Cl)c(Cl)c3)CC2)cc1F

0.739

View
COc1ccc(CN2CCN(C(=O)Cc3c(F)cccc3F)CC2)cc1F

0.739

View
CCC(CC)CC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.739

View
COc1ccc(CN2CCN(C(C)=O)CC2)cc1F

0.738

View
COc1ccc(CN2CCN(C(=O)CC(C)C)CC2)cc1F

0.733

View
COc1ccc(CN2CCN(C(=O)CCC(C)=O)CC2)cc1F

0.733

View
COC(=O)CC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.733

View
COc1ccc(CN2CCN(C(=O)CSC)CC2)cc1F

0.733

View
COc1ccc(CN2CCN(C(=O)CC(F)(F)F)CC2)cc1F

0.733

View
COCCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.733

View
CCc1ccc(CC(=O)N2CCN(Cc3ccc(OC)c(F)c3)CC2)cc1

0.733

View
COc1ccc(CN2CCN(C(=O)CCO)CC2)cc1F

0.733

View
COc1ccc(CC(=O)N2CCN(Cc3ccc(OC)c(F)c3)CC2)cc1

0.733

View
COc1ccc(CN2CCN(C(=O)CC(C)(C)C)CC2)cc1F

0.733

View
COc1ccc(CN2CCN(C(=O)CSC(F)F)CC2)cc1F

0.733

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(C)cc3)CC2)cc1F

0.733

View
COc1ccc(CN2CCN(C(=O)Cc3ccccc3)CC2)cc1F

0.733

View
COc1ccc(CN2CCN(C(=O)CON)CC2)cc1F

0.733

View
COc1ccc(CN2CCN(C(=O)CN3CCCC3)CC2)cc1F

0.733

View
COc1ccc(CN2CCN(C(=O)CCN)CC2)cc1F

0.733

View
CNCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.733

View
COc1ccc(OCC(=O)N2CCN(Cc3ccc(OC)c(F)c3)CC2)cc1

0.723

View
C=C(Cl)CCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.723

View
COc1ccc(CN2CCN(C(N)=O)CC2)cc1F

0.721

View
COC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.721

View
CCCCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.717

View
COc1ccc(CN2CCN(C(=O)CC#N)CC2)cc1F

0.717

View
CCOCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.717

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(Br)cc3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)CCC(C)C)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(O)cc3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)CCC(N)=O)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(O)c(F)c3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)CS(C)(=O)=O)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)CC3CC3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)CC(C)OC)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)CC(C)(F)F)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)Cc3cc(OC)c(OC)c(OC)c3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)CN3CCN(C)CC3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(CC(=O)N3CCN(C(C)=O)CC3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(CC(=O)N3CCN(C)CC3)CC2)cc1F

0.717

View
CCC(=O)N1CCCN(Cc2ccc(OC)c(F)c2)CC1

0.717

View
COc1ccc(CN2CCN(C(=O)CN3CCNCC3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)C[C@@H](C)N)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)C[C@H](C)N)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(CN)cc3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)COCC(=O)O)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)Cc3ccc(N)cc3)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)CC(C)N)CC2)cc1F

0.717

View
COc1ccc(CN2CCN(C(=O)Cc3c(F)cccc3Cl)CC2)cc1F

0.714

View
COc1ccc(CN2CCN(C(=O)COc3ccc(Cl)cc3)CC2)cc1F

0.714

View
COc1ccc(CN2CCN(C(=O)C34CC(F)(C3)C4)CC2)cc1F

0.711

View
COc1ccc(CN2CCN(CC(=O)N3CCCC3)CC2)cc1F

0.711

View
COc1ccc(CN2CCN(CC(=O)N3CCC3)CC2)cc1F

0.711

View
COc1ccc(CC(=O)N2CCN(Cc3cccc(Cl)c3)CC2)cc1F

0.708

View
COc1ccc(CN2CCN(C(=O)COc3ccccc3)CC2)cc1F

0.708

View
COc1ccc(CN2CCN(C(=O)COc3ccc(F)cc3)CC2)cc1F

0.708

View
COc1ccc(CN2CCN(C(=O)Cc3cc(Cl)ccc3OC)CC2)cc1F

0.708

View
COc1ccc(CN2CCN(C(=O)CCc3ccc(Cl)cc3)CC2)cc1F

0.708

View
COc1ccc(CN2CCN(C(=O)Cc3cccc(Cl)c3)CC2)cc1F

0.708

View
COc1ccc(CN2CCN(C(=O)Cc3c(C)cccc3C)CC2)cc1F

0.708

View
CCOc1ccc(CC(=O)N2CCN(Cc3ccc(OC)c(F)c3)CC2)cc1

0.708

View
COc1ccc(CN2CCN(C(=O)CCc3ccc(OC)c(Cl)c3)CC2)cc1F

0.708

View
COc1ccc(CN2CCN(C(=O)CC3CC3(Cl)Cl)CC2)cc1F

0.708

View
COc1ccc(CN2CCN(C(=O)C3(C)CC3)CC2)cc1F

0.705

View
COc1ccc(CN2CCN(C(=O)N3CCC3)CC2)cc1F

0.705

View
COc1ccc(CN2CCN(C(=O)N3CCCC3)CC2)cc1F

0.705

View
COc1ccc(CN2CCN(C(=O)C3(F)CC3)CC2)cc1F

0.705

View
COc1ccc(CN2CCN(C(=O)N(C)C)CC2)cc1F

0.705

View
COc1ccc(N2CCN(C(=O)CCl)CC2)cc1F

0.705

View
COc1ccc(CN2CCN(C(=O)C(=O)N3CCCC3)CC2)cc1F

0.705

View
COc1ccc(CN2CCN(C(=O)C(=O)N3CCC3)CC2)cc1F

0.705

View
COc1cc(CN2CCN(C(=O)Cc3ccc(OC)c(F)c3)CC2)cc(OC)c1

0.702

View
CCCCCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.702

View
COc1ccc(CN2CCN(C(=O)CCC(=O)N3CCOCC3)CC2)cc1F

0.702

View
COc1ccc(CN2CCN(C(=O)CCc3ccc(OC)c(OC)c3)CC2)cc1F

0.702

View
COc1ccc(CN2CCN(C(=O)CCc3ccc(F)cc3)CC2)cc1F

0.702

View
COc1cc(CC(=O)N2CCN(Cc3ccc(OC)c(F)c3)CC2)ccc1C

0.702

View
COc1ccc(CN2CCN(C(=O)Cc3ccncc3)CC2)cc1F

0.702

View
CCSCC(=O)N1CCN(Cc2ccc(OC)c(F)c2)CC1

0.702

View
COc1ccc(C(=O)N2CCN(C(=O)c3cccc(F)c3)CC2)cc1

0.200

View
COc1ccc(CN(C)C(=O)CN2CCN(CCO)CC2)cc1F

0.200

View
COc1ccc(CN2CCN(C(=O)c3ccc(C#N)cc3)CC2)cc1F

0.200

View
COc1ccc(CN2CCN(C(=O)[C@@H](N)C(C)C)CC2)cc1F.Cl.Cl

0.195

View
COc1ccc(CN2CCN(C(=O)C3(N)CC3)CC2)cc1F.Cl.Cl

0.193

View
COCCN1CCN(Cc2ccc(OC)c(F)c2)CC1

0.191

View
COc1ccc(CN2CCN(C(=O)c3ccc4ccccc4c3)CC2)cc1F

0.189

View
COc1ccc(CN2CCN(Cc3cccc(F)c3)CC2)cc1

0.186

View
COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1.Cl

0.186

View
COc1ccc(C(=O)N2CCNCC2)cc1F

0.181

View
COc1ccc(CN2CCN(C(=O)c3ccccc3F)CC2)cc1F

0.179

View
COc1ccc(CN2CCN(CCO)CC2)cc1F

0.179

View
COc1ccc(CN2CCN(C(=O)c3cccc(F)c3)CC2)cc1

0.177

View
COc1ccc(C(=O)N2CCN(Cc3cccc(F)c3)CC2)cc1

0.177

View
CCN(CC(=O)NC)Cc1ccc(OC)c(F)c1

0.174

View
COc1ccc(C(=O)N2CCN(Cc3ccccc3)CC2)cc1F

0.174

View
COc1ccc(CN2CCN(C(=O)C(C)(C)N)CC2)cc1F

0.168

View
COc1ccc(CN2CCN(C(=O)c3ccc(C)cc3)CC2)cc1F

0.156

View
CCN(Cc1ccc(OC)c(F)c1)C(=O)CCl

0.156

View
COc1ccc(CN(C)C(=O)CCl)cc1F

0.156

View
COc1ccc(CN2CCNCC2)cc1F

0.155

View
COc1ccc(CN2CCNC(=O)C2)cc1F

0.138

View
COc1ccc(CN2CCN(C(=O)CN)CC2)cc1F

0.092

View
N1(CC2=CC(F)=C(OC)C=C2)CCN(C(C)=O)CC1

0.946

View
N1(CC2=CC(F)=C(OC)C=C2)CCN(C=O)CC1

0.901

View
N(CC1=CC(F)=C(OC)C=C1)(C)CC(N1CCN(C)CC1)=O

0.872

View
C(N1CCN(CC)CC1)(=O)C1=CC(F)=C(OC)C=C1

0.871

View
C(N1CCN(C)CC1)(=O)C1=CC(F)=C(OC)C=C1

0.865

View

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