Molecule Details

COc1cc(C)c(CN2CCN(C(=O)CCl)CC2)cc1OC
piperazine-chloroacetamide Enamine Mcule MolPort
Molecular Properties
SMILES:
COc1cc(C)c(CN2CCN(C(=O)CCl)CC2)cc1OC
MW: 326.14
Fraction sp3: 0.56
HBA: 4
HBD: 0
Rotatable Bonds: 5
TPSA: 42.01
cLogP: 1.9
Covalent Warhead: ✔️
Covalent Fragment: ✔️
Source
Enamine SCR: Z1562119896
Mcule: MCULE-7788259532
MolPort: MolPort-005-310-689
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3

View

Cc1ccccc1CN1CCN(C(=O)CCl)CC1

MAK-UNK-7c9d1431-20
0.508

View
COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1F

SAD-SAT-5b1897b2-5
0.493

View
O=C(CCl)N1CCN(Cc2cc(O)ccc2O)CC1

NEH-REV-107bcf72-5
0.477

View
COCCc1ccc(Cl)cc1CN1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-37
0.472

View
COc1cc(CN2CCN(C(=O)CCl)CC2)c2ccccc2c1

DAR-DIA-fb20be43-7
0.453

View
CCNc1ncc(OC)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-5
0.453

View
O=C(CCl)N1CCN(Cc2cscc2Cl)CC1

SAD-SAT-bc31ec01-1
0.453

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.439

View
Cc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-2
0.439

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.429

View
CNC(=O)Cc1c(C)cccc1CN1CCN(C(=O)CCl)CC1

STE-UNK-13e151dd-1
0.427

View
COCc1cc(CN2CCN(C(=O)CCl)CC2)sc1Br

JOH-UNI-27ac80fd-38
0.425

View
Cc1ccc(CN2CCN(C(=O)CCl)CC2)o1

MAR-LAB-ca4662a6-2
0.424

View
Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-41
0.423

View
Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

TAT-ENA-80bfd3e5-20
0.423

View
COCc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

MED-COV-4280ac29-33
0.423

View
CNC(=O)c1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-17
0.421

View
CCNc1ncc(F)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-1
0.421

View
O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.419

View
O=C(CCl)N1CCN(Cc2cc(F)cc3ccccc23)CC1

DAR-DIA-fb20be43-2
0.419

View
COc1ccccc1-n1cc(CN2CCN(C(=O)CCl)CC2)nn1

ANT-STE-dbb91f63-3
0.418

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1C(=O)N1CCC(O)CC1

MAK-UNK-e4a48a85-26
0.418

View
CCNc1ccccc1CN1CCN(C(=O)CCl)CC1

SEL-UNI-cd366922-6
0.417

View
CN(C)Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

JOK-SYG-18591e8f-1
0.414

View
O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.413

View
Cc1nc(CN2CCN(C(=O)CCl)CC2)cs1

SAD-SAT-5b1897b2-2
0.412

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

PAU-UNI-52c0427f-1
0.408

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

BRU-LEF-ae0885ba-1
0.408

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-4
0.408

View
COc1cc(CN2CCN(C(=O)CCl)CC2)c2[nH]cc(CCNC(C)=O)c2c1

DAR-DIA-fb20be43-14
0.407

View
O=C(CCl)N1CCN(Cc2cc(O)cc3c2OCO3)CC1

NEH-REV-107bcf72-3
0.405

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15
0.403

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

AAR-POS-d2a4d1df-35
0.403

View
O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

MED-COV-4280ac29-31
0.403

View
O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

AAR-POS-d2a4d1df-40
0.403

View
Cc1cc(CN2CCN(C(=O)CCl)CC2)cc(S(N)(=O)=O)c1

SAD-SAT-581007d4-4
0.403

View
CC(=O)Nc1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-18
0.403

View
COCCc1cc(Br)sc1CN1CCN(C(=O)CCl)CC1

JOH-UNI-27ac80fd-39
0.403

View
Cc1ccc(CN2CCCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-21
0.400

View
CCNc1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-3
0.397

View
COc1ccc(-n2cc(CN3CCN(C(=O)CCl)CC3)nn2)cc1

ANT-STE-dbb91f63-1
0.397

View
O=C(CCl)N1CCN(Cc2cc(F)cc(Cl)c2)CC1

SAD-SAT-581007d4-1
0.397

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

MAT-POS-2db6411e-2
0.397

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

SAD-SAT-581007d4-7
0.397

View
COC(=O)C(NS(=O)(=O)NS(N)(=O)=O)c1ccc(CN2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-af83ef51-14
0.395

View
COc1cc(CN2CCN(C(=O)CCl)CC2)c2c(c1)C(CCNC(C)=O)=CC2

DAR-DIA-fb20be43-13
0.395

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

PAU-UNI-19862c28-1
0.395

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

DAR-DIA-fb20be43-8
0.395

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

LON-WEI-8f408cad-7
0.394

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

AAR-POS-0daf6b7e-13
0.394

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

MAK-UNK-212f693e-8
0.394

View
NS(=O)(=O)CCc1ccccc1CN1CCN(C(=O)CCl)CC1

MIH-UNI-e573136b-5
0.392

View
Nc1csc(O)c1CN1CCN(C(=O)CCl)CC1

ASH-SAT-43770c7d-5
0.391

View
COc1cnc(CNC(=O)N2CCOCC2)c(CN2CCN(C(=O)CCl)CC2)c1

DAR-DIA-fb20be43-18
0.391

View
COc1cccc(-n2cc(CN3CCN(C(=O)CCl)CC3)nn2)c1

ANT-STE-dbb91f63-2
0.390

View
N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAT-POS-ee51dedd-1
0.389

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCO3)CC1

MAK-UNK-7c9d1431-14
0.389

View
CC(=O)NCCc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc12

JOK-SYG-302da050-1
0.388

View
CC(=O)NCCc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc12

NAU-LAT-f723e322-1
0.388

View
CC(=O)NCCc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc12

STU-CHA-bc0a9883-1
0.388

View
CC(=O)NCCc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc12

DAR-DIA-fb20be43-11
0.388

View
CC(=O)NCCC1=CCc2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc21

DAR-DIA-fb20be43-10
0.388

View
O=C(CCl)N1CCN(Cc2cccs2)CC1

LON-WEI-8f408cad-5
0.388

View
N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-6ca90168-14
0.388

View
O=C(CCl)N1CCN(Cc2cccs2)CC1

AAR-POS-0daf6b7e-17
0.388

View
O=C(CCl)N1CCN(Cc2ccco2)CC1

MAK-UNK-7c9d1431-28
0.388

View
O=C(CCl)N1CCN(Cc2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-2
0.388

View
CCNc1cc(CN2CCN(C(=O)CCl)CC2)c(C#N)cn1

DAV-CRI-d1e0885a-2
0.388

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)CCO3)CC1

MAK-UNK-7c9d1431-18
0.387

View
O=C(CCl)N1CCN(Cc2scc3ccccc23)CC1

PAU-UNI-b2b6b158-1
0.387

View
N#Cc1cnc(CCO)cc1CN1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-35
0.385

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1OC

MAK-UNK-7c9d1431-19
0.384

View
NS(=O)(=O)c1ccc2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc2c1

DAR-DIA-fb20be43-12
0.383

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-23
0.382

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

AAR-POS-0daf6b7e-12
0.382

View
O=C(CCl)N1CCN(Cc2cc(Cl)ccc2CNC(=O)N2CCOCC2)CC1

STU-CHA-6cae54d3-1
0.381

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3cnccc23)CC1

JOO-PER-58e158bd-1
0.380

View
N#Cc1cnc(NCO)cc1CN1CCN(C(=O)CCl)CC1

DAV-CRI-d1e0885a-3
0.380

View
CN(C)C(=O)c1ccc(CNS(C)(=O)=O)c(CN2CCN(C(=O)CCl)CC2)c1

TAM-UNI-d1c3dd9f-4
0.378

View
COCCc1cc(CN2CCN(C(=O)CCl)CC2)c2[nH]cc(CCNC(C)=O)c2c1

JOK-SYG-b9f02a42-3
0.378

View
O=C(CCl)N1CCN(Cc2ccc(CS(=O)(=O)F)cc2)CC1

JIA-UNI-93b03cae-1
0.377

View
CC(=O)Nc1cc(C#N)cc(CN2CCN(C(=O)CCl)CC2)c1

TAM-UNI-d1c3dd9f-16
0.377

View
N#Cc1cc(CN2CCN(C(=O)CCl)CC2)c2ccccc2c1

DAR-DIA-fb20be43-6
0.375

View
NS(=O)(=O)c1ccc2cccc(CN3CCN(C(=O)CCl)CC3)c2c1

MIH-UNI-e573136b-4
0.375

View
O=C(CCl)N1CCN(Cc2cc(Cl)ccc2CNS(=O)(=O)N2CCOCC2)CC1

STU-CHA-6d5cfe2b-1
0.372

View
CC(=O)NCCc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cc(Cl)cc12

DAR-DIA-fb20be43-15
0.372

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1CC(NC(=O)CS(N)(=O)=O)C(C)O

MAK-UNK-af83ef51-15
0.371

View
CC(=O)N1CCCc2cccc(CN3CCN(C(=O)CCl)CC3)c2C1

TAM-UNI-d1c3dd9f-13
0.370

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAR-TRE-6a44bbf2-54
0.370

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAK-UNK-7c9d1431-16
0.370

View
N#Cc1ccsc1CN1CCN(C(=O)CCl)CC1

DAV-CRI-d1e0885a-1
0.370

View
NS(=O)(=O)Cc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc12

JOK-SYG-302da050-2
0.369

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1C

ASH-SAT-43770c7d-10
0.368

View
O=C(NCc1ccc(Cl)cc1CN1CCN(C(=O)CCl)CC1)[C@@H]1CCCOC1

STU-CHA-7b3b91d5-1
0.367

View
NS(=O)(=O)c1ccc2c(CN3CCN(C(=O)CCl)CC3)cccc2c1

DAR-DIA-fb20be43-9
0.366

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3cccc(OCCN4CCOCC4)c23)CC1

SEA-TRI-67e8f1c7-1
0.366

View
NS(=O)(=O)c1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-3
0.365

View
CC(=O)NCCc1cn(C)c2c(CN3CCN(C(=O)CCl)CC3)cccc12

TAM-UNI-d1c3dd9f-20
0.365

View
CC(=O)NCCC1C=Nc2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc21

JOO-PER-d7ab4f65-1
0.364

View
NS(=O)(=O)CCNc1ncccc1CN1CCN(C(=O)CCl)CC1

STU-CHA-464c0256-1
0.361

View
CCC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.780

View
COCC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.762

View
COc1cc(C)c(CN2CCN(C(=O)CO)CC2)cc1OC

0.762

View
COc1cc(C)c(CN2CCN(C(C)=O)CC2)cc1OC

0.732

View
COC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.732

View
COc1cc(C)c(CN2CCN(C(=O)CSC)CC2)cc1OC

0.727

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCCC3)CC2)cc1OC

0.727

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(CC(=O)N4CCCC4)CC3)CC2)cc1OC

0.727

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)CN4CCCC4)CC3)CC2)cc1OC

0.727

View
COc1cc(C)c(CN2CCN(C(=O)CC(C)C)CC2)cc1OC

0.727

View
COc1cc(C)c(CN2CCN(C(=O)N3CCCC3)CC2)cc1OC

0.714

View
COc1cc(C)c(CN2CCN(C(=O)CS(C)(=O)=O)CC2)cc1OC

0.711

View
COc1cc(C)c(CN2CCN(C(=O)COC(C)=O)CC2)cc1OC

0.711

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCCCCCC3)CC2)cc1OC

0.711

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(C)=O)CC3)CC2)cc1OC

0.711

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCCCCC3)CC2)cc1OC

0.711

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C)CC3)CC2)cc1OC

0.711

View
CCN1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.711

View
COC(=O)N1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.711

View
CCC(=O)N1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.711

View
COC(=O)CN1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.711

View
CCC(=O)N1CCCN(Cc2cc(OC)c(OC)cc2C)CC1

0.711

View
COc1cc(C)c(CN2CCN(CC(=O)N3CCCC3)CC2)cc1OC

0.705

View
COc1cc(C)c(CN2CCN(C(=O)N3CCCCC3)CC2)cc1OC

0.698

View
COc1cc(C)c(CN2CCN(C(=O)C(=O)N3CCCC3)CC2)cc1OC

0.698

View
COc1cc(C)c(CN2CCN(C(=O)N(C)C)CC2)cc1OC

0.698

View
COC(=O)CSCC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.696

View
COc1cc(C)c(CN2CCN(C(=O)CN(C)OC)CC2)cc1OC

0.696

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)N4CCCC4)CC3)CC2)cc1OC

0.696

View
COCC(=O)N1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.696

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)CO)CC3)CC2)cc1OC

0.696

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCSSCC3)CC2)cc1OC

0.696

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(CC(N)=O)CC3)CC2)cc1OC

0.696

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCNCC3)CC2)cc1OC

0.696

View
CCN(CC)CC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.696

View
COc1cc(C)c(CN2CCN(C(=O)COc3ccc(Cl)cc3)CC2)cc1OC

0.694

View
COc1cc(C)c(CN2CCN(CC(=O)N3CCCCC3)CC2)cc1OC

0.689

View
COc1cc(C)c(CN2CCN(CC(=O)N3CCCCCC3)CC2)cc1OC

0.689

View
COc1ccc(C)cc1CN1CCN(C(=O)CCl)CC1

0.689

View
COc1cc(C)c(CN2CCN(C(=O)Cc3ccc(Cl)cc3)CC2)cc1OC

0.688

View
COc1cc(C)c(CN2CCN(C(=O)Cc3ccccc3Cl)CC2)cc1OC

0.688

View
COc1cc(C)c(CN2CCN(C(=O)COc3ccc(C)cc3)CC2)cc1OC

0.688

View
COc1cc(C)c(CN2CCN(C(=O)C(C)(C)C)CC2)cc1OC

0.682

View
COc1cc(C)c(CN2CCN(C(=O)C(C)C)CC2)cc1OC

0.682

View
CNC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.682

View
COc1cc(C)c(CN2CCN(C(=O)N3CCNCC3)CC2)cc1OC

0.682

View
COc1cc(C)c(CN2CCN(C(=O)CSCC(N)=O)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CSCC(C)=O)CC2)cc1OC

0.681

View
CCS(=O)(=O)CC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.681

View
CCC(=O)OCC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.681

View
COCC(=O)OCC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCOCC3)CC2)cc1OC

0.681

View
CCCN(CCC)CC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.681

View
COc1cc(C)c(CN(C)CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)cc1OC

0.681

View
COCCN1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCSCC3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3C4CCC3CC4)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)N4CCCCC4)CC3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCC(F)(F)CC3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)CN(C)C)CC3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN(C3CC3)C3CC3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCC4(CC3)CC4)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)N(C)C)CC3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN(C)CC(=O)N3CCCC3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3CC(C)C(C)C3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CN3C(=O)CCC3=O)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)CC3CCCCC3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)Cc3ccc(C)cc3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCN(C(=O)Cc3ccccc3)CC2)cc1OC

0.681

View
COc1cc(C)c(CN2CCCN(CC(=O)N3CCCC3)CC2)cc1OC

0.674

View
COc1cc(C)c(CN2CCN(C(=O)COC(=O)C(C)(Cl)Cl)CC2)cc1OC

0.673

View
COc1cc(C)c(CN2CCN(C(=O)COc3ccc(F)cc3)CC2)cc1OC

0.673

View
COc1cc(C)c(CN2CCN(C(=O)CSCC(C)(C)C)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)COC(=O)C(C)C)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)COC(=O)CO)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)COC(=O)C(C)(C)C)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)COC(=O)C(C)=C(C)C)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCC(C)CC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(CCO)CC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(CC(C)C)CC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(CC(F)(F)F)CC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN(C)C(C)(C)C)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(C)C)CC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)C(C)(C)C)CC3)CC2)cc1OC

0.667

View
CCN1CCCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN(C)C3CC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)C(C)C)CC3)CC2)cc1OC

0.667

View
COC(=O)CN(C)CC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CC=CCC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(C)(C)C)CC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(=O)CC(C)C)CC3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CC4CC4C3)CC2)cc1OC

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCS(=O)(=O)CC3)CC2)cc1OC

0.667

View
COc1ccccc1CN1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCS(=O)CC3)CC2)cc1OC

0.667

View
C=C1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.667

View
CCC1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.667

View
CNC(=O)N1CCN(CC(=O)N2CCN(Cc3cc(OC)c(OC)cc3C)CC2)CC1

0.667

View
COc1cc(C)c(CN2CCN(C(=O)CN3C[C@H](O)[C@H](O)C3)CC2)cc1OC

0.667

View
CCC(CC)(CC)NCC(=O)N1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.667

View
COc1cc(CN2CCN(Cc3ccccc3C)CC2)cc(OC)c1OC

0.200

View
COc1ccc(CN(CCN(C)C)Cc2ccccc2C)cc1O

0.200

View
COCCN1CCN(Cc2cc(OC)c(OC)cc2C)CC1

0.199

View
COc1ccc(CNC(=O)CN(C)Cc2ccccc2C)cc1OC

0.197

View
COc1cc(C(=O)N2CCN(Cc3ccccc3C)CC2)cc(OC)c1OC

0.196

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

0.195

View
Cl.O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

0.195

View
COc1ccc(CN2CCN(C(=O)c3ccccc3)CC2)cc1OC

0.191

View
CCN(CC)C(=O)CN1CCN(CC(=O)N(C)Cc2cc(OC)c(OC)cc2C)CC1

0.189

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCO3)CC1

0.174

View
Cl.O=C(CCl)N1CCN(Cc2ccc3c(c2)OCO3)CC1

0.174

View
COc1ccc(CN2CCN(Cc3ccccc3C)CC2)cc1OC.O=C(O)C(=O)O

0.174

View
CCN(Cc1ccc(OC)c(OC)c1)C(=O)CN1CCN(Cc2ccccc2C)CC1

0.172

View
COc1ccc(C(=O)N2CCN(Cc3ccccc3C)CC2)cc1OC

0.163

View
COc1ccc(CN2CCN(Cc3ccccc3C)CC2)cc1OC

0.158

View
COc1cc(C)c(CN2CCNCC2)cc1OC

0.158

View
COc1cc(C)c(CN2CCNCC2)cc1OC.Cl.Cl

0.150

View
COc1ccc(CN2CCN(C(C)=O)CC2)cc1OC

0.143

View
COc1cc(C)c(CN2CCNC(=O)C2)cc1OC

0.128

View
COc1cc(C)c(CN2CCN(C(=O)CN3CCN(C(C)=O)CC3)CC2)cc1OC

0.115

View
COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1OC.Cl

0.068

View
C(N1CCN(CC)CC1)(=O)C1=CC(OC)=C(OC)C=C1

0.796

View
C(N1CCN(C)CC1)(=O)C1=CC(OC)=C(OC)C=C1

0.791

View
N1(CC(NCC2=CC(OC)=C(OC)C=C2)=O)CCN(C(C2=C(C)C=CC=C2)=O)CC1

0.790

View
C(N1CCN(CC2=CC=C3C(OCO3)=C2)CC1)(=O)COC1C=CC(C)=C(C)C=1

0.786

View
C(N1CCN(CCC)CC1)(=O)C1=CC(OC)=C(OC)C=C1

0.782

View


Discussion: