Molecule Details

NS(=O)(=O)CCc1ccccc1CN1CCN(C(=O)CCl)CC1
piperazine-chloroacetamide Assayed
Molecular Properties
SMILES:
NS(=O)(=O)CCc1ccccc1CN1CCN(C(=O)CCl)CC1
MW: 359.879
Fraction sp3: 0.53
HBA: 4
HBD: 1
Rotatable Bonds: 6
TPSA: 83.71
cLogP: 0.4006
Covalent Warhead: ✔️
Covalent Fragment: ✔️
Activity Data
IC50 (µM) - Fluorescence: 2.71702061388963
IC50 (µM) - RapidFire: 0.83373139690581
Trypsin IC50 (µM): 99.0
pIC50 (µM) - Fluorescence 5.56590706660068
Average Inhibition @ 20 µM - Fluorescence: 101.27855
Average Inhibition @ 50 µM - Fluorescence: 102.5626
Average Inhibition @ 50 µM - RapidFire: 100.0
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-04-17
Synthesis Location: enamine
Shipped: 2020-07-08
CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

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CC(=O)NCCc1c[nH]c2ccc(F)cc12

AAR-POS-d2a4d1df-2

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CC(=O)Nc1cnccc1C

MAK-UNK-6435e6c2-8

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O=C(CC1CCCCC1)Nc1cccnc1

ALE-HEI-f28a35b5-9

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O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

MED-COV-4280ac29-31

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NC(=O)[C@H]1CCC[C@H]1c1ccsc1

AAR-POS-d2a4d1df-14

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CN1CCN(C(=O)Cc2c[nH]c3ncccc23)CC1

AAR-POS-d2a4d1df-20

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Cc1ccccc1CN1CCN(C(=O)CCl)CC1

MAK-UNK-7c9d1431-20
0.531

View
NS(=O)(=O)CCNc1ncccc1CN1CCN(C(=O)CCl)CC1

STU-CHA-464c0256-1
0.506

View
NS(=O)(=O)CCc1ccccc1CN1CC2CC1CN2C(=O)CCl

MAK-UNK-bae89c02-4
0.493

View
O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

MED-COV-4280ac29-31
0.486

View
O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

AAR-POS-d2a4d1df-40
0.486

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CCNc1ccccc1CN1CCN(C(=O)CCl)CC1

SEL-UNI-cd366922-6
0.479

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NS(=O)(=O)c1ccc2c(CN3CCN(C(=O)CCl)CC3)cccc2c1

DAR-DIA-fb20be43-9
0.474

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NC(=O)C1CCCN1c1ccccc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-9
0.468

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NC(=O)C1CCCN1c1ccccc1CN1CCN(C(=O)CCl)CC1

DUN-NEW-f8ce3686-2
0.468

View
O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.468

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NS(=O)(=O)c1ccc2cccc(CN3CCN(C(=O)CCl)CC3)c2c1

MIH-UNI-e573136b-4
0.468

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NS(=O)(=O)Cc1nc2cccc(CN3CCN(C(=O)CCl)CC3)c2[nH]1

STU-CHA-0f79177c-1
0.457

View
O=C(CCl)N1CCN(Cc2cc(O)ccc2O)CC1

NEH-REV-107bcf72-5
0.456

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O=C(CCl)N1CCN(Cc2ccco2)CC1

MAK-UNK-7c9d1431-28
0.455

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COCCc1ccc(Cl)cc1CN1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-37
0.453

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Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-41
0.444

View
Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

TAT-ENA-80bfd3e5-20
0.444

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CC(=O)Nc1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-18
0.442

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O=C(CCl)N1CCN(Cc2cc(F)cc3ccccc23)CC1

DAR-DIA-fb20be43-2
0.440

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O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.438

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Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1CC(NC(=O)CS(N)(=O)=O)C(C)O

MAK-UNK-af83ef51-15
0.437

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O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

DAR-DIA-fb20be43-8
0.434

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O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

PAU-UNI-19862c28-1
0.434

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O=C(CCl)N1CCN(Cc2cscc2Cl)CC1

SAD-SAT-bc31ec01-1
0.433

View
Cc1cc(CN2CCN(C(=O)CCl)CC2)cc(S(N)(=O)=O)c1

SAD-SAT-581007d4-4
0.425

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NS(=O)(=O)c1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-3
0.425

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Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.420

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O=C(CCl)N1CCN(Cc2ccc(CS(=O)(=O)F)cc2)CC1

JIA-UNI-93b03cae-1
0.420

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NS(=O)(=O)c1ccc2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc2c1

DAR-DIA-fb20be43-12
0.420

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COc1cc(CN2CCN(C(=O)CCl)CC2)c2ccccc2c1

DAR-DIA-fb20be43-7
0.418

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CN(C)C(=O)c1ccc(CNS(C)(=O)=O)c(CN2CCN(C(=O)CCl)CC2)c1

TAM-UNI-d1c3dd9f-4
0.415

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N#Cc1cc(CN2CCN(C(=O)CCl)CC2)c2ccccc2c1

DAR-DIA-fb20be43-6
0.412

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O=C(CCl)N1CCN(Cc2cccs2)CC1

AAR-POS-0daf6b7e-17
0.412

View
O=C(CCl)N1CCN(Cc2cccs2)CC1

LON-WEI-8f408cad-5
0.412

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CCC(=O)N1CCN(Cc2ccccc2CN2CCN(C(=O)C(O)F)CC2)CC1

JON-UIO-066ce08b-11
0.411

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CNC(=O)Cc1c(C)cccc1CN1CCN(C(=O)CCl)CC1

STE-UNK-13e151dd-1
0.410

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O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

AAR-POS-d2a4d1df-35
0.406

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O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

AAR-POS-0daf6b7e-12
0.406

View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15
0.406

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-23
0.406

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Cc1ccc(CN2CCN(C(=O)CCl)CC2)o1

MAR-LAB-ca4662a6-2
0.406

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CNC(=O)c1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-17
0.405

View
NS(=O)(=O)Cc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cc(F)cc12

JOK-SYG-302da050-2
0.405

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O=C(CCl)N1CCN(Cc2c(F)cccc2Cl)CC1

AHN-SAT-de2502ba-15
0.403

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O=C(CCl)N1CCN(Cc2cnc(-c3ccccc3)nc2)CC1

MAK-UNK-af83ef51-1
0.400

View
CC(=O)N1CCN(Cc2ccc(CCS(N)(=O)=O)cc2)CC1

WIL-LEE-23e8b574-4
0.400

View
CC(=O)NCCc1cn(C)c2c(CN3CCN(C(=O)CCl)CC3)cccc12

TAM-UNI-d1c3dd9f-20
0.400

View
O=C1NCCCc2cccc(CN3CCN(C(=O)CCl)CC3)c21

TAM-UNI-d1c3dd9f-15
0.398

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

LON-WEI-8f408cad-7
0.397

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

AAR-POS-0daf6b7e-13
0.397

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

MAK-UNK-212f693e-8
0.397

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NS(=O)(=O)c1ccc2cc(CN3CCN(C(=O)CCl)CC3)ccc2c1

SEL-UNI-cd366922-7
0.392

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COc1ccc(CN2CCN(C(=O)CCl)CC2)cc1F

SAD-SAT-5b1897b2-5
0.392

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COc1cc(C)c(CN2CCN(C(=O)CCl)CC2)cc1OC

SAD-SAT-65574d3f-10
0.392

View
O=C(CCl)N1CCN(Cc2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-2
0.391

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N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-6ca90168-14
0.391

View
O=C(CCl)N1CCN(Cc2cc(Cl)ccc2CNS(=O)(=O)N2CCOCC2)CC1

STU-CHA-6d5cfe2b-1
0.391

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CC(=O)NCCc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cccc12

DUN-NEW-f8ce3686-24
0.391

View
CC(=O)N1CCCc2cccc(CN3CCN(C(=O)CCl)CC3)c2C1

TAM-UNI-d1c3dd9f-13
0.390

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.388

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CC(=O)N1CCN(Cc2cccc(CCS(N)(=O)=O)c2)CC1

JAN-GHE-1d98ec1c-2
0.387

View
O=C1Cc2c(cccc2CN2CCN(C(=O)CCl)CC2)CCN1

TAM-UNI-d1c3dd9f-14
0.386

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1C(=O)N1CCC(O)CC1

MAK-UNK-e4a48a85-26
0.386

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CCNc1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-3
0.383

View
O=C(CCl)N1CCN(C/C=C/c2ccccc2)CC1

AHN-SAT-de2502ba-14
0.380

View
O=C(CCl)N1CCN(C/C=C/c2ccccc2)CC1

SAD-SAT-65574d3f-1
0.380

View
CN(C)Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

JOK-SYG-18591e8f-1
0.378

View
NS(=O)(=O)CC(=O)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-8
0.377

View
Cc1ccccc1CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-10
0.377

View
CCc1ccccc1NC(=O)CN1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-27
0.377

View
Nc1csc(O)c1CN1CCN(C(=O)CCl)CC1

ASH-SAT-43770c7d-5
0.375

View
O=C(CCl)N1CCN(CCCc2ccccc2)CC1

MAK-UNK-15efde89-1
0.375

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCO3)CC1

MAK-UNK-7c9d1431-14
0.373

View
N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAT-POS-ee51dedd-1
0.373

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAR-TRE-6a44bbf2-54
0.373

View
O=C(CCl)N1CCN(Cc2ccc3c(c2)OCCO3)CC1

MAK-UNK-7c9d1431-16
0.373

View
N#Cc1ccsc1CN1CCN(C(=O)CCl)CC1

DAV-CRI-d1e0885a-1
0.373

View
N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1C(=O)N1CCC(O)CC1

MAK-UNK-10dfa458-38
0.372

View
O=C(CCl)N1CCN(Cc2scc3ccccc23)CC1

PAU-UNI-b2b6b158-1
0.372

View
O=C(CCl)N1CCN(Cc2cc(O)cc3c2OCO3)CC1

NEH-REV-107bcf72-3
0.372

View
N#Cc1cnc(CCO)cc1CN1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-35
0.370

View
O=C(NCc1ccc(Cl)cc1CN1CCN(C(=O)CCl)CC1)[C@@H]1CCCOC1

STU-CHA-7b3b91d5-1
0.370

View
Nc1nc(CN2CCN(C(=O)CCl)CC2)ncc1Cc1ccccc1

MED-COV-4280ac29-19
0.369

View
NS(=O)(=O)c1ccc(Br)c(CCN2CCCN(C(=O)CCl)CC2)c1

PED-UNI-89deb5c9-1
0.369

View
O=C(CCl)N1CCN(Cc2cc(Cl)ccc2CNC(=O)N2CCOCC2)CC1

STU-CHA-6cae54d3-1
0.368

View
NS(=O)(=O)c1cccc(-n2cc(CN3CCN(C(=O)CCl)CC3)nn2)c1

NIM-UNI-594fbbb6-3
0.368

View
NS(=O)(=O)c1cccc(-n2cc(CN3CCN(C(=O)CCl)CC3)nn2)c1

NIM-UNI-bb610069-3
0.368

View
O=C(CCl)N1CCN(Cc2cn(Cc3ccccc3)nn2)CC1

STE-KUL-2e0d2e88-7
0.367

View
COC(=O)C(NS(=O)(=O)NS(N)(=O)=O)c1ccc(CN2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-af83ef51-14
0.367

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3cnccc23)CC1

JOO-PER-58e158bd-1
0.366

View
N#Cc1cnc(NCO)cc1CN1CCN(C(=O)CCl)CC1

DAV-CRI-d1e0885a-3
0.366

View
O=C(CCl)N1CCN(CC2=CC3OCOC3C=C2)CC1

SAD-SAT-bc31ec01-7
0.364

View
O=C1CN(C(=O)NCc2ccc(Cl)cc2CN2CCN(C(=O)CCl)CC2)CCN1

STU-CHA-5350f95a-1
0.363

View
O=C(CCl)N1CCN(Cc2cc(F)cc(Cl)c2)CC1

SAD-SAT-581007d4-1
0.361

View
Cc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-2
0.361

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

MAT-POS-2db6411e-2
0.361

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

SAD-SAT-581007d4-7
0.361

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

PAU-UNI-52c0427f-1
0.358

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

BRU-LEF-ae0885ba-1
0.358

View
CCNc1ncc(C#N)cc1CN1CCN(C(=O)CCl)CC1

DAR-DIA-fb20be43-4
0.358

View
O=C(CCl)N1CCN(Cc2ccccc2Cl)CC1

0.628

View
NS(=O)(=O)CCCC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.612

View
Cc1ccccc1CN1CCN(C(=O)CCl)CC1

0.600

View
NS(=O)(=O)CCCCCC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.588

View
Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

0.583

View
NS(=O)(=O)CCN1CCN(C(=O)CCl)CC1

0.581

View
O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

0.574

View
Cc1ccccc1CN1CCN(C(=O)CCCS(N)(=O)=O)CC1

0.569

View
COc1ccccc1CN1CCN(C(=O)CCl)CC1

0.562

View
Cc1ccccc1CN1CCCN(C(=O)CCCS(N)(=O)=O)CC1

0.556

View
NS(=O)(=O)CCCC(=O)N1CCN(Cc2cccc3ccccc23)CC1

0.547

View
Cc1ccccc1CN1CCN(C(=O)CCCCCS(N)(=O)=O)CC1

0.547

View
Cc1ccccc1CN1CCN(C(=O)CCCCCCS(N)(=O)=O)CC1

0.547

View
Cc1ccccc1CN1CCN(C(=O)CN2CCN(CCS(N)(=O)=O)CC2)CC1

0.547

View
NS(=O)(=O)CCN1CCN(C(=O)CCc2ccccc2Cl)CC1

0.538

View
COc1ccccc1CN1CCN(C(=O)CCCS(N)(=O)=O)CC1

0.537

View
NS(=O)(=O)c1ccc(CCC(=O)N2CCN(Cc3ccccc3Cl)CC2)cc1

0.537

View
Cc1ccccc1CN1CCCN(C(=O)CCCCCS(N)(=O)=O)CC1

0.536

View
Cc1ccccc1CN1CCCN(C(=O)CCCCCCS(N)(=O)=O)CC1

0.536

View
Cc1ccccc1CN1CCCN(C(=O)CN2CCN(CCS(N)(=O)=O)CC2)CC1

0.536

View
O=C(CCl)N1CCCN(Cc2ccccc2)CC1

0.532

View
NS(=O)(=O)CCN1CCN(C(=O)Cc2ccccc2Cl)CC1

0.529

View
CCc1ccccc1CC(=O)N1CCN(CCS(N)(=O)=O)CC1

0.529

View
Nc1ccccc1CCC(=O)N1CCN(CCS(N)(=O)=O)CC1

0.529

View
NS(=O)(=O)c1ccc(CC(=O)N2CCN(Cc3ccccc3Cl)CC2)cc1

0.528

View
NS(=O)(=O)CCCCCC(=O)N1CCN(Cc2cccc3ccccc23)CC1

0.527

View
NS(=O)(=O)c1ccc(OCC(=O)N2CCN(Cc3ccccc3Cl)CC2)cc1

0.527

View
NS(=O)(=O)CCCCCCC(=O)N1CCN(Cc2cccc3ccccc23)CC1

0.527

View
Cc1ccccc1CN1CCN(C(=O)CN(C)CCS(N)(=O)=O)CC1

0.527

View
O=C(CO)N1CCN(Cc2ccccc2CN2CCN(C(=O)CO)CC2)CC1

0.523

View
CCC(=O)N1CCN(Cc2ccccc2CN2CCN(C(=O)CC)CC2)CC1

0.523

View
NCC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.522

View
NS(=O)(=O)CCN1CCN(C(=O)CCc2ccccc2F)CC1

0.519

View
NS(=O)(=O)CCN1CCN(C(=O)CCc2ccccc2Br)CC1

0.519

View
NS(=O)(=O)CCN1CCN(C(=O)CCCc2ccccc2Cl)CC1

0.519

View
NS(=O)(=O)CCCNC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.519

View
COc1ccccc1CN1CCN(C(=O)CCCCCS(N)(=O)=O)CC1

0.518

View
COc1ccccc1CN1CCN(C(=O)CCCCCCS(N)(=O)=O)CC1

0.518

View
Cc1ccccc1CN1CCCN(C(=O)CN(C)CCS(N)(=O)=O)CC1

0.517

View
CCC(=O)N1CCCN(Cc2ccccc2CN2CCCN(C(=O)CC)CC2)CC1

0.511

View
NS(=O)(=O)CCN1CCN(Cc2ccccc2Cl)CC1

0.511

View
CS(=O)(=O)CCC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.510

View
NS(=O)(=O)CCN1CCN(C(=O)Cc2ccccc2Br)CC1

0.510

View
NS(=O)(=O)CCN1CCN(C(=O)Cc2ccccc2F)CC1

0.510

View
Nc1ccccc1CCC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.510

View
O=C(CCl)N1CCCN(Cc2cc(F)ccc2F)CC1

0.510

View
NS(=O)(=O)CCCC(=O)N1CCCN(Cc2ccccc2)CC1

0.509

View
Cc1ccccc1CCC(=O)N1CCN(CCS(N)(=O)=O)CC1

0.509

View
NS(=O)(=O)CCCN1CCN(C(=O)Cc2ccccc2Cl)CC1

0.509

View
NS(=O)(=O)CCN1CCN(C(=O)NCc2ccccc2CN2CCCC2)CC1

0.509

View
NS(=O)(=O)CCCCNC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.509

View
Cc1ccccc1CN1CCN(C(=O)CCc2ccc(S(N)(=O)=O)cc2)CC1

0.500

View
CS(=O)(=O)CC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.500

View
NS(=O)(=O)c1ccc(CC(=O)N2CCN(Cc3ccccc3Cl)CC2)s1

0.500

View
CC(C)(C)S(=O)(=O)CC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.500

View
NS(=O)(=O)CCN1CCN(C(=O)NCc2ccccc2CN2CCCCCC2)CC1

0.500

View
Cc1ccccc1CC(=O)N1CCN(CCS(N)(=O)=O)CC1

0.500

View
NS(=O)(=O)CCN1CCN(C(=O)Cc2ccccc2I)CC1

0.500

View
NS(=O)(=O)CCN1CCN(C(=O)Cc2ccccc2O)CC1

0.500

View
N#CCc1ccccc1CC(=O)N1CCN(CCS(N)(=O)=O)CC1

0.500

View
NC(=O)c1ccccc1CCC(=O)N1CCN(CCS(N)(=O)=O)CC1

0.500

View
NS(=O)(=O)CCN1CCN(C(=O)CCCc2ccccc2Br)CC1

0.500

View
Cc1ccccc1CN1CCN(C(=O)COC(=O)CCCS(N)(=O)=O)CC1

0.500

View
CN(C)CC(=O)N1CCN(Cc2ccccc2CN2CCN(C(=O)CN(C)C)CC2)CC1

0.500

View
NS(=O)(=O)CCCCN1CCN(C(=O)Cc2ccccc2Cl)CC1

0.500

View
NC(=O)N1CCCN(Cc2ccccc2CN2CCCN(C(N)=O)CC2)CC1

0.500

View
NS(=O)(=O)CCN1CCN(CC(=O)N2CCN(Cc3ccccc3)CC2)CC1

0.500

View
COC(=O)Cc1ccccc1CN1CCN(CCS(N)(=O)=O)CC1

0.500

View
CCc1ccccc1CN1CCN(CCS(N)(=O)=O)CC1

0.500

View
Nc1ccccc1CC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.500

View
O=C(CCl)N1CCN(CCc2ccccc2)CC1

0.500

View
Cc1ccccc1CN1CCCN(C(=O)CCc2ccc(S(N)(=O)=O)cc2)CC1

0.492

View
Cc1ccccc1CN1CCN(C(=O)COc2ccc(S(N)(=O)=O)cc2)CC1

0.491

View
NS(=O)(=O)c1cnn(CC(=O)N2CCN(Cc3ccccc3Cl)CC2)c1

0.491

View
NS(=O)(=O)CCCC(=O)N1CCN(Cc2cccc3cc[nH]c23)CC1

0.491

View
CN1CCN(Cc2ccccc2CNC(=O)N2CCN(CCS(N)(=O)=O)CC2)CC1

0.491

View
Cc1ccccc1CN1CCN(C(=O)Cc2ccc(S(N)(=O)=O)cc2)CC1

0.491

View
NS(=O)(=O)CCCCCC(=O)N1CCCN(Cc2ccccc2)CC1

0.491

View
NS(=O)(=O)c1cc(C(=O)N2CCN(Cc3ccccc3Cl)CC2)ccc1Cl

0.491

View
O=C(CS(=O)(=O)CCCc1ccccc1)N1CCN(Cc2ccccc2Cl)CC1

0.491

View
NS(=O)(=O)CCCCCCC(=O)N1CCCN(Cc2ccccc2)CC1

0.491

View
NS(=O)(=O)CCN1CCN(C(=O)CCc2cccc3ccccc23)CC1

0.491

View
O=C(CCS(=O)(=O)c1ccccc1)N1CCN(Cc2ccccc2Cl)CC1

0.491

View
NS(=O)(=O)c1ccc(C(=O)N2CCN(Cc3ccccc3Cl)CC2)cc1

0.491

View
CCCS(=O)(=O)CC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.491

View
CS(=O)(=O)CCCC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.491

View
NS(=O)(=O)CCN1CCN(C(=O)Cc2ccccc2C(F)(F)F)CC1

0.491

View
NS(=O)(=O)CCN1CCN(C(=O)CCc2c(Cl)cccc2Cl)CC1

0.491

View
NS(=O)(=O)CCCN1CCN(C(=O)Cc2ccccc2F)CC1

0.491

View
CC(C)(O)CC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.490

View
NS(=O)(=O)C1(C(=O)N2CCN(Cc3ccccc3Cl)CC2)CC1

0.490

View
NS(=O)(=O)CCN1CCN(C(=O)CCc2ccccc2)CC1

0.490

View
NS(=O)(=O)CCN1CCN(C(=O)CCC(=O)N2CCN(c3ccccc3)CC2)CC1

0.490

View
CC(C)(N)CC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.490

View
O=C(CC(F)(F)F)N1CCN(Cc2ccccc2Cl)CC1

0.490

View
NS(=O)(=O)CCCN1CCN(Cc2ccccc2Cl)CC1

0.490

View
NCCC(=O)N1CCN(Cc2ccccc2Cl)CC1

0.490

View
O=C(CCl)N1CCN(Cc2ccccn2)CC1

0.490

View
O=C(CCl)N1CCCN(Cc2ccc(F)cc2)CC1

0.490

View
COCC(=O)N1CCN(Cc2ccccc2CN2CCN(C(=O)COC)CC2)CC1

0.489

View

C(N1CCN(CC)CC1)(=O)C1=C(CC)C=CC=C1

0.718

View
C(N1CCN(C)CC1)(=O)C1=C(CC)C=CC=C1

0.713

View
N1(CC2=C(C)C=CC=C2)CCN(C(C)=O)CC1

0.710

View
N1(CCN2CCC3=C(C=CC=C3)C2)CCN(C(C)=O)CC1

0.708

View
C(N1CCN(CCS(C)(=O)=O)CC1)(=O)C1=C(CC)C=CC=C1

0.701

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