Submission Details

Molecule(s):
CC(=O)NCCc1c[nH]c2ccc(F)cc12

AAR-POS-d2a4d1df-2

CC(=O)NCCc1c[nH]c2ccc(F)cc12

CC(=O)Nc1cnccc1C

AAR-POS-d2a4d1df-3
Duplicate of:
MAK-UNK-6435e6c2-8

CC(=O)Nc1cnccc1C

CN1CCCc2ccc(S(N)(=O)=O)cc21

AAR-POS-d2a4d1df-4

CN1CCCc2ccc(S(N)(=O)=O)cc21

Cc1ccc(OCC(=O)N2CCN(C)CC2)cc1

AAR-POS-d2a4d1df-6

Cc1ccc(OCC(=O)N2CCN(C)CC2)cc1

Cc1cc(CN(C)C(=O)NC2CC2)no1

AAR-POS-d2a4d1df-9

Cc1cc(CN(C)C(=O)NC2CC2)no1

O=C(Nc1ccccc1)Nc1cccnc1

AAR-POS-d2a4d1df-11

O=C(Nc1ccccc1)Nc1cccnc1

3-aminopyridine-like Made Check Availability on Manifold View
O=C(CC1CCCCC1)Nc1cccnc1

AAR-POS-d2a4d1df-13
Duplicate of:
ALE-HEI-f28a35b5-9

O=C(CC1CCCCC1)Nc1cccnc1

Duplicate 3-aminopyridine-like Made Check Availability on Manifold View
CC(=O)NC(Cc1ccc(O)cc1)C(=O)NCC#CBr

AAR-POS-d2a4d1df-16

CC(=O)NC(Cc1ccc(O)cc1)C(=O)NCC#CBr

CN1CCN(C(=O)Cc2c[nH]c3ncccc23)CC1

AAR-POS-d2a4d1df-20

CN1CCN(C(=O)Cc2c[nH]c3ncccc23)CC1

N#Cc1ccc(CNC(=O)N2CCOCC2)cc1

AAR-POS-d2a4d1df-21

N#Cc1ccc(CNC(=O)N2CCOCC2)cc1

O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

AAR-POS-d2a4d1df-22
Duplicate of:
LON-WEI-8f408cad-3

O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

Duplicate piperazine-chloroacetamide Assayed Check Availability on Manifold View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

AAR-POS-d2a4d1df-23
Duplicate of:
LON-WEI-8f408cad-4

O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

Duplicate piperazine-chloroacetamide Assayed Check Availability on Manifold View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24

Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

piperazine-chloroacetamide Made Check Availability on Manifold View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-25

Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

piperazine-chloroacetamide Made Check Availability on Manifold View
O=C(CCl)NNC(=O)c1cc2c(s1)CCCC2

AAR-POS-d2a4d1df-26

O=C(CCl)NNC(=O)c1cc2c(s1)CCCC2

Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27

Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

piperazine-chloroacetamide Made Check Availability on Manifold View
O=C(CCl)N1CCN(c2ccccc2[N+](=O)[O-])CC1

AAR-POS-d2a4d1df-28

O=C(CCl)N1CCN(c2ccccc2[N+](=O)[O-])CC1

piperazine-chloroacetamide Made Check Availability on Manifold View
O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

AAR-POS-d2a4d1df-29

O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

piperazine-chloroacetamide Made Check Availability on Manifold View
O=C(CCl)N1CCCC(c2nc3ccccc3s2)C1

AAR-POS-d2a4d1df-30

O=C(CCl)N1CCCC(c2nc3ccccc3s2)C1

O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

AAR-POS-d2a4d1df-32
Duplicate of:
LON-WEI-8f408cad-2

O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

Duplicate piperazine-chloroacetamide Assayed Check Availability on Manifold View
O=C(CCl)N1CCOC(c2ccc(F)cc2)C1

AAR-POS-d2a4d1df-33

O=C(CCl)N1CCOC(c2ccc(F)cc2)C1

O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

AAR-POS-d2a4d1df-34

O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

piperazine-chloroacetamide Made Check Availability on Manifold View
O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

AAR-POS-d2a4d1df-35
Duplicate of:
MED-COV-4280ac29-15

O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

Duplicate piperazine-chloroacetamide Assayed Check Availability on Manifold View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1

AAR-POS-d2a4d1df-36

Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1

piperazine-chloroacetamide Made Check Availability on Manifold View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-37

N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

piperazine-chloroacetamide Made Check Availability on Manifold View
O=C(CCl)Nc1cccc(C(=O)N2CCSCC2)c1

AAR-POS-d2a4d1df-38

O=C(CCl)Nc1cccc(C(=O)N2CCSCC2)c1

CC(NC(=O)CCl)c1cccc2ccccc12

AAR-POS-d2a4d1df-39

CC(NC(=O)CCl)c1cccc2ccccc12

O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

AAR-POS-d2a4d1df-40
Duplicate of:
MED-COV-4280ac29-31

O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

Duplicate piperazine-chloroacetamide Assayed Check Availability on Manifold View
Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-41

Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

CC(=O)N[C@H](C(=O)NCC#CBr)[C@H](C)O

AAR-POS-d2a4d1df-42

CC(=O)N[C@H](C(=O)NCC#CBr)[C@H](C)O

CC(=O)NC(CC(N)=O)C(=O)NCC#CBr

AAR-POS-d2a4d1df-43

CC(=O)NC(CC(N)=O)C(=O)NCC#CBr

O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

AAR-POS-d2a4d1df-44

O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

piperazine-chloroacetamide Made Check Availability on Manifold View

Design Rationale:

First batch of fragments so we have a Moonshot CID for them

Inspired By:
Discussion: