Molecule Details

O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
piperazine-chloroacetamide Enamine Mcule MolPort
View on Fragalysis x1308
Molecular Properties
SMILES:
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1
MW: 337.228
Fraction sp3: 0.42
HBA: 3
HBD: 0
Rotatable Bonds: 3
TPSA: 57.69
cLogP: 1.4117
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-08173
Enamine SCR: Z56949574
Enamine REAL: Z56949574
Enamine Extended REAL: m_270062____7595236____8147258
Mcule: MCULE-4357480999
MolPort: MolPort-002-465-805

Activated haloaromatics

Hetero_hetero

Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27
0.706

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

MAR-TRE-6a44bbf2-58
0.706

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-68
0.706

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

KAY-MCD-d0fe5261-1
0.706

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CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-13
0.692

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CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-78
0.692

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(C3CC3)cc2)CC1

MAK-UNK-c74072e5-8
0.667

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1

MAK-UNK-7c9d1431-6
0.667

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-17
0.667

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAR-TRE-6a44bbf2-21
0.667

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAK-UNK-7c9d1431-9
0.667

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CCOc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-22
0.661

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(Cl)c2)CC1

MAK-UNK-7c9d1431-10
0.655

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

ABB-MCD-f8003a30-1
0.625

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

MAR-TRE-6a44bbf2-32
0.625

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O=C(CCl)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1

SAD-SAT-bc31ec01-5
0.623

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O=C(CCl)N1CCN(S(=O)(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-2
0.611

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O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)CC1

MAT-POS-ee51dedd-2
0.582

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-7c9d1431-8
0.579

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAR-TRE-6a44bbf2-26
0.579

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O=C(CCl)N1CCN(S(=O)(=O)c2cpcc(Cl)c2)CC1

SAD-SAT-bc31ec01-4
0.569

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

LON-WEI-8f408cad-4
0.561

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

AAR-POS-d2a4d1df-23
0.561

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

MAR-TRE-6a44bbf2-18
0.561

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O=C(CCl)N1CCN(S(=O)(=O)C2=CCC=C2)CC1

SAD-SAT-3a925b8b-9
0.554

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1

MAK-UNK-7c9d1431-12
0.544

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COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1OC

MAK-UNK-7c9d1431-19
0.541

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O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=C2)CC1

MAK-UNK-d4768348-1
0.526

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O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=N2)CC1

MAK-UNK-d4768348-4
0.526

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-15
0.526

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

TAT-ENA-80bfd3e5-25
0.524

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1

MAK-UNK-7c9d1431-3
0.524

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

MAK-UNK-7c9d1431-4
0.524

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O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

LON-WEI-8f408cad-2
0.517

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O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

AAR-POS-d2a4d1df-32
0.517

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

MAR-TRE-6a44bbf2-4
0.517

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O=C(CCl)N1CCN(S(=O)(=O)C2=CCN=C2)CC1

MAK-UNK-d4768348-5
0.517

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O=C(CCl)N1CCN(S(=O)(=O)C2=CCS(O)=C2)CC1

MAK-UNK-d4768348-8
0.517

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CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

TAT-ENA-80bfd3e5-43
0.516

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CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-65
0.516

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CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-11
0.516

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAK-UNK-7c9d1431-7
0.516

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAR-TRE-6a44bbf2-49
0.516

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAK-UNK-7c9d1431-5
0.516

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAR-TRE-6a44bbf2-31
0.516

View
CS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-7
0.508

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1

MAK-UNK-7c9d1431-1
0.508

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1

MAR-TRE-6a44bbf2-38
0.508

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NS(=O)(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-f2e2579e-5
0.507

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

AAR-POS-d2a4d1df-34
0.500

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1

IND-SYN-6c8299e8-2
0.500

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O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

MAR-TRE-6a44bbf2-52
0.500

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3
0.500

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

MAR-TRE-6a44bbf2-8
0.500

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

AAR-POS-d2a4d1df-22
0.500

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cc3cccc4ccccc34)cc2)CC1

MED-COV-4280ac29-5
0.500

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O=C(CCl)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccc([N+](=O)[O-])cc3)CC2)CC1

SAD-SAT-9a6c5cf3-5
0.493

View
Cc1cc(/C=C/C(=O)N2CCN(S(=O)(=O)c3ccc(Cl)cc3)CC2)no1

NAU-LAT-f723e322-6
0.493

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)CC1

MAK-UNK-7c9d1431-2
0.493

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)CC1

MAR-TRE-6a44bbf2-36
0.493

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CN[SH]=C2)CC1

MAK-UNK-d4768348-2
0.492

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O=C(CCl)N1CCN(S(=O)(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-3
0.492

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C(Cl)CC=C2)CC1

SAD-SAT-3a925b8b-6
0.492

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Br)s2)CC1

NIM-UNI-05f93fcc-1
0.492

View
N#Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-f2e2579e-10
0.486

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Nc1cc(-c2cc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)ccc2F)cs1

MAK-UNK-c74072e5-9
0.479

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COS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-9
0.469

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O=C(CCl)N1CCN(S(=O)(=O)C2=C3CC3[SH]=C2)CC1

SAD-SAT-3a925b8b-7
0.468

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O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.464

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O=C(CCl)N1CC2CC1CN2S(=O)(=O)c1ccc(Cl)cc1

MAK-UNK-3f402c2b-15
0.460

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

AAR-POS-0daf6b7e-3
0.460

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1

AAR-POS-d2a4d1df-36
0.460

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-13
0.460

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

WAR-XCH-79d12f6e-6
0.460

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O=C(CCl)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccc(C4CCCCC4)cc3)CC2)CC1

SAD-SAT-9a6c5cf3-9
0.459

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O=C(CCl)N1CCN(S(=O)(=O)C2=NC[SH]=C2)CC1

MAK-UNK-d4768348-3
0.459

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O=C(CCl)N1CCCN(S(=O)(=O)c2cccc(F)c2)CC1

BEN-DND-76ad4ac9-14
0.455

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COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-30
0.448

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COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-45
0.448

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-37
0.446

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-7
0.446

View
Cc1ccc(S(=O)(=O)N2CCCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-9a6c5cf3-2
0.446

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC3OCOC3C=C2)CC1

SAD-SAT-bc31ec01-8
0.441

View
O=C(CCl)N1CCCN(S(=O)(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-12
0.439

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Cc1noc(C)c1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-24
0.435

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cc(F)ccc2F)CC1

BEN-DND-76ad4ac9-10
0.435

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc(O)cc3)s2)CC1

NIM-UNI-05f93fcc-14
0.435

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)C[C@@H]1Oc1ccc(F)cc1

SAL-INS-1ea6d4ee-1
0.434

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O=C(CCl)N1CCCN(S(=O)(=O)c2ccccc2F)CC1

BEN-DND-76ad4ac9-11
0.433

View
O=C(COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1)NCc1ccc2c(c1)OCO2

DAV-UNK-07f953a2-3
0.430

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccccc3Cl)s2)CC1

NIM-UNI-05f93fcc-3
0.429

View
O=C(CCl)N1CCN(S(=O)(=O)/C=C/c2ccccc2)CC1

MAK-UNK-7c9d1431-27
0.429

View
Cc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-11
0.426

View
O=C(C(=O)N1Cc2ccccc2C(c2ccccc2)C1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

JAR-IMP-ed466bb3-4
0.425

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccccc3)s2)CC1

NIM-UNI-05f93fcc-2
0.420

View
O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAK-UNK-7c9d1431-23
0.419

View
O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAR-TRE-6a44bbf2-28
0.419

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cccs2)CC1

BEN-DND-76ad4ac9-13
0.418

View
O=C(c1cc(=O)[nH]c2ccc(F)cc12)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

MAT-POS-590ac91e-67
0.418

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O=C(CCl)N1CCN(S(=O)(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-2
0.415

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

1.000

View
O=C(CO)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.755

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CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.740

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NCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.740

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O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1)N1CCC1

0.712

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NCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.712

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CSCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.712

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O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(Br)C=C2)CC1

0.706

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CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.698

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CS(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.698

View
CC(C)C1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.698

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CC(C)(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.698

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CC(=O)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.698

View
CC(=O)C1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.692

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O=C(CC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

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O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1)N1CCCC1

0.685

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CN(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

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O=C(CC(F)(F)F)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

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O=C(CC1CC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

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CC(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

View
N#CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

View
COCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

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NOCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

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CNCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

View
CCS(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.685

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CC(C)(C)C1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.679

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C=CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.679

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NC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.673

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CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.673

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CC(=O)N1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)CC1

0.673

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CC(C)(O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.673

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NCCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.673

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COC(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.673

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O=C(CCl)N1CCN(S(=O)(=O)C2=CC=CC=C2)CC1

0.667

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CC(C)(C)OCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.667

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COC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.667

View
N#CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.667

View
O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1)N1CCCCCC1

0.661

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CCC(CC)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
CCC(=O)N1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)CC1

0.661

View
O=C(CN1CCCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
CN1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)CC1

0.661

View
CCCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
CS(=O)(=O)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
C[C@@H](N)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
C[C@H](N)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
CC(N)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
O=C(CC1CCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
CNS(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
O=C(CCC(F)F)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.661

View
O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1)N1CCCCCCC1

0.649

View
O=C(CCS(=O)(=O)C1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
O=C(CSC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
CC(C)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
C#CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1)N1CCOCC1

0.649

View
NC(=O)CSCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
CC(C)(C)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
CCOCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
CSCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
CC(=O)CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
COCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
O=C(CCC(F)(F)F)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
CC(C)S(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.649

View
CCCC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.643

View
O=C(CCC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.638

View
O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1)C1=CC=C(Cl)C=C1

0.638

View
O=C(CC1=CC=CC=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.638

View
O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1)N1CCSCC1

0.638

View
O=C1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)CC1

0.638

View
O=C(CN1CCCCCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.638

View
O=C(O)COCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.638

View
CCCCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.638

View
CCN1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)CC1

0.638

View
CCC(C)(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.638

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(Cl)C(Cl)=C2)CC1

0.630

View
O=C(COC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.627

View
O=C(CNS(=O)(=O)C1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.627

View
O=C(CNC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.627

View
O=C(CCC(=O)N1CCS(=O)CC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.627

View
O=C(CC1=C(F)C=CC=C1F)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.627

View
O=C(CC1=CC=CC(Cl)=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.623

View
CCC(=O)N1CCCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.621

View
O=C(CC1=CC=C(F)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.617

View
O=C(CS(=O)(=O)C1=CC=CC=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.617

View
O=C(CC1=CC=C(Cl)C(Cl)=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.617

View
O=C(CC1=CC=C(Br)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.617

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.617

View
CCC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.617

View
O=C(CCOC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.607

View
O=C(CCCC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.607

View
O=C(CCC(=O)N1CCSC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.607

View
O=C(COC1=CC=CC=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.597

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=CC(Cl)=C2)CC1

0.596

View
O=C(CC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(CCCl)C=C2)CC1

0.571

View
O=C(CCl)N1CCCN(S(=O)(=O)C2=CC=C(F)C=C2)CC1

0.567

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CCl)CC2)C=C1

0.567

View
O=C(CC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(F)C=C2)CC1

0.565

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC(Cl)=CC=C2Cl)CC1

0.542

View
O=C(CCl)N1CCCN(S(=O)(=O)C2=CC=CC=C2)CC1

0.542

View
CCC(C)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.200

View
O=C(CSc1ccc(Cl)cc1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.200

View
N#CCCN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.200

View
CCCCNC(=O)CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.200

View
CC(C(=O)NC(C)(C)C)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.200

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

0.199

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

0.199

View
CN(C)CC(=O)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1

0.198

View
CN(C)C(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.195

View
O=C(CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)NC1CC1

0.195

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

0.195

View
CN(CC(=O)N1CCNC(=O)C1)S(=O)(=O)c1ccc(Cl)cc1

0.194

View
CCN(CC)C(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.194

View
CCNC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.194

View
CCN(CC)C(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1

0.194

View
CC(=O)NCCNS(=O)(=O)c1ccc(Cl)cc1

0.193

View
O=C(NCCNS(=O)(=O)c1ccc(Cl)cc1)C(Cl)(Cl)Cl

0.192

View
CC(=O)N1CCN(S(=O)(=O)c2cc(Cl)c(Cl)cc2Cl)CC1

0.192

View
COCCOCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.192

View
CC1CCCCN1CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.192

View
CC(C)C(C)N(CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)C1CC1

0.192

View
O=C(Cc1ccccc1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.191

View
CNC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.190

View
CC(=O)N1CCN(CC(C)(C)NS(=O)(=O)c2ccc(Cl)cc2)CC1

0.188

View
CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)c(Cl)c2Cl)CC1

0.188

View
O=C(C1CCCC1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.186

View
CC1CCCN(CC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)cc3)CC2)C1

0.186

View
CC1CC(C)CN(CC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)cc3)CC2)C1

0.186

View
O=C(CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC1

0.186

View
CN1CCN(C(=O)CN(CC(=O)N2CCN(C)CC2)S(=O)(=O)c2ccc(Cl)cc2)CC1

0.185

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

0.184

View
CN1CCN(CC(=O)NCCNS(=O)(=O)c2ccc(Cl)cc2)CC1

0.182

View
CCN1CCN(CC(=O)NCCNS(=O)(=O)c2ccc(Cl)cc2)CC1

0.182

View
CC1CC1C(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.182

View
O=C(CCC1CCCC1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.181

View
CCN(CC)CCNC(=O)CN(C)S(=O)(=O)c1ccc(Cl)cc1

0.180

View
O=C(O)CCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.178

View
C=CCNC(=O)CCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.178

View
O=C(CCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCC1

0.178

View
N#CCNC(=O)CCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.178

View
CC(C)NC(=O)CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.176

View
CC(C)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.174

View
CCCN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.174

View
CC(Cl)C(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

0.174

View
O=C(CN1CCOCC1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.173

View
CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)c(C)c2)CC1

0.173

View
CC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

0.173

View
O=S(=O)(c1ccc(Cl)cc1)N1CCN(CCO)CC1

0.173

View
Cl.O=S(=O)(c1ccc(Cl)cc1)N1CCN(CCO)CC1

0.173

View
CC(=O)N1CCN(S(=O)(=O)c2cccc(Cl)c2)CC1

0.173

View
CC(=O)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1

0.173

View
C=CC(=O)NCCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.172

View
NC(=O)CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.169

View
CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2F)CC1

0.169

View
CCCNC(=O)CCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.169

View
CC(=O)N1CCN(S(=O)(=O)c2c(Cl)cccc2Cl)CC1

0.168

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1

0.167

View
CCN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c1ccc(Cl)cc1

0.166

View
CCN1CCN(C(=O)CN(CC)S(=O)(=O)c2ccc(Cl)cc2)CC1

0.166

View
CC(C)NC(=O)CN1CCN(CC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1.O=C(O)C(=O)O

0.164

View
CC1CCN(CC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1

0.164

View
O=C(CCl)NCCNS(=O)(=O)c1ccc(Cl)cc1

0.160

View
CSCCN(C)CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.159

View
O=S(=O)(NCCN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1

0.158

View
Cl.O=S(=O)(NCCN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)c1ccc(Cl)cc1

0.158

View
CN1CCN(C(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2)CC1

0.156

View
CCN1CCN(C(=O)CN(C)S(=O)(=O)c2ccc(Cl)cc2)CC1

0.156

View
CC(=O)N1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)c3ccc(Cl)cc3)CC2)CC1

0.154

View
CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.153

View
CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1.Cl

0.153

View
CCNC(=O)CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.150

View
CCNC(=O)CCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.149

View
CCN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.147

View
CC(C)NC(=O)C(=O)NCCN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.145

View
CC(=O)N[C@@H](C)C(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.144

View
C=CCCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.144

View
CC(C)CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.139

View
O=C(CCCCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.139

View
O=C(CN1CCCCC1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.139

View
O=C(CCCN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.139

View
NC(=O)NCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.133

View
O=C(C(F)F)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.133

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1

0.124

View
CC(C)(C)C(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.123

View
CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)c3ccccc23)CC1

0.121

View
CC(C)(C)NCC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.117

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

0.113

View
CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2Cl)CC1

0.112

View
O=CN1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.100

View
CC(=O)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.047

View
N1(S(=O)(=O)C2=CC=C(Cl)C=C2)CCN(C(C)=O)CC1

0.956

View
N1(S(=O)(=O)C2=CC=C(Cl)C=C2)CCN(C=O)CC1

0.912

View
N1(S(=O)(=O)C2=CC=CC(Cl)=C2)CCN(C(C)=O)CC1

0.909

View
C(N1CCN(S(=O)(C2=CC=CC=C2)=O)CC1)(C(Cl)Cl)=O

0.903

View
C(N1CCN(S(=O)(C2=CC=CC=C2)=O)CC1)(=O)C

0.896

View

Discussion: