Molecule Details

O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1
piperazine-chloroacetamide Enamine Mcule MolPort
View on Fragalysis x1402
Molecular Properties
SMILES:
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1
MW: 343.257
Fraction sp3: 0.5
HBA: 4
HBD: 0
Rotatable Bonds: 3
TPSA: 57.69
cLogP: 1.4732
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-22857
Enamine SCR: Z147647636
Enamine REAL: Z210803702
Enamine Extended REAL: m_270062____7598600____8147258
Mcule: MCULE-8136806651
MolPort: MolPort-002-470-578

Activated haloaromatics

Hetero_hetero

O=C(CCl)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccc(Cl)s3)CC2)CC1

SAD-SAT-f2e2579e-3
0.717

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Br)s2)CC1

NIM-UNI-05f93fcc-1
0.679

View
Cc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-11
0.581

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccccc3Cl)s2)CC1

NIM-UNI-05f93fcc-3
0.578

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccccc3)s2)CC1

NIM-UNI-05f93fcc-2
0.571

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3
0.571

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

MAR-TRE-6a44bbf2-52
0.571

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

AAR-POS-d2a4d1df-22
0.571

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc[nH]3)s2)CC1

NIM-UNI-05f93fcc-5
0.569

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc(O)cc3)s2)CC1

NIM-UNI-05f93fcc-14
0.562

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccncc3)s2)CC1

NIM-UNI-310206f0-69
0.562

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3nccs3)s2)CC1

NIM-UNI-05f93fcc-13
0.554

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3cncnc3)s2)CC1

NIM-UNI-310206f0-67
0.545

View
Cc1cc(C)cc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)c1

NIM-UNI-05f93fcc-7
0.545

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3c[nH]cn3)s2)CC1

NIM-UNI-05f93fcc-17
0.537

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3cn[nH]c3)s2)CC1

NIM-UNI-310206f0-71
0.537

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ncco3)s2)CC1

NIM-UNI-05f93fcc-9
0.529

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3cccnc3)s2)CC1

NIM-UNI-05f93fcc-6
0.529

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc(C(F)(F)F)cc3)s2)CC1

NIM-UNI-05f93fcc-10
0.529

View
COc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-15
0.529

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

AAR-POS-d2a4d1df-44
0.526

View
C=CC(=O)N(CC)CC(=O)N1CCCN(S(=O)(=O)c2ccc(Cl)s2)CC1

AHN-SAT-b1e6fbb2-1
0.521

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O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)CC1

MAT-POS-ee51dedd-2
0.517

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=C2)CC1

MAK-UNK-d4768348-1
0.517

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCC=C2)CC1

SAD-SAT-3a925b8b-9
0.517

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(C3=CCOCC3)s2)CC1

NIM-UNI-310206f0-68
0.514

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAK-UNK-7c9d1431-9
0.509

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAR-TRE-6a44bbf2-21
0.509

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1

MAK-UNK-7c9d1431-12
0.508

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O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

LON-WEI-8f408cad-2
0.508

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CN[SH]=C2)CC1

MAK-UNK-d4768348-2
0.508

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

MAR-TRE-6a44bbf2-4
0.508

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

AAR-POS-d2a4d1df-32
0.508

View
O=C(CCl)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1

SAD-SAT-bc31ec01-5
0.500

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(OCC3CCOCC3)s2)CC1

NIM-UNI-310206f0-70
0.500

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(C3CC3)cc2)CC1

MAK-UNK-c74072e5-8
0.492

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

MAR-TRE-6a44bbf2-58
0.492

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

KAY-MCD-d0fe5261-1
0.492

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O=C(CCl)N1CCN(S(=O)(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-2
0.492

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27
0.492

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-68
0.492

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(Cl)c2)CC1

MAK-UNK-7c9d1431-10
0.484

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C3CC3[SH]=C2)CC1

SAD-SAT-3a925b8b-7
0.484

View
CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-13
0.483

View
CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-78
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C(Cl)CC=C2)CC1

SAD-SAT-3a925b8b-6
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCN=C2)CC1

MAK-UNK-d4768348-5
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCS(O)=C2)CC1

MAK-UNK-d4768348-8
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc4cc[nH]c4c3)s2)CC1

NIM-UNI-05f93fcc-4
0.480

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cccs2)CC1

BEN-DND-76ad4ac9-13
0.477

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

MAR-TRE-6a44bbf2-18
0.475

View
CS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-7
0.475

View
O=C(CCl)N1CCN(S(=O)(=O)C2=NC[SH]=C2)CC1

MAK-UNK-d4768348-3
0.475

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

LON-WEI-8f408cad-4
0.475

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

AAR-POS-d2a4d1df-23
0.475

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cc3cccc4ccccc34)s2)CC1

MAK-UNK-e05327b2-8
0.474

View
CCOc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-22
0.469

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

MAR-TRE-6a44bbf2-8
0.468

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

AAR-POS-d2a4d1df-34
0.468

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1

MAK-UNK-7c9d1431-6
0.468

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-7c9d1431-8
0.468

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-17
0.468

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAR-TRE-6a44bbf2-26
0.468

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3cccc4cc[nH]c34)s2)CC1

NIM-UNI-05f93fcc-16
0.468

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=N2)CC1

MAK-UNK-d4768348-4
0.467

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

MAR-TRE-6a44bbf2-32
0.460

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

ABB-MCD-f8003a30-1
0.460

View
O=C(CCl)N1CCN(S(=O)(=O)c2cpcc(Cl)c2)CC1

SAD-SAT-bc31ec01-4
0.460

View
O=C(CCl)N1CCN(S(=O)(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-3
0.459

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3cccc4ncoc34)s2)CC1

NIM-UNI-05f93fcc-12
0.456

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)C[C@@H]1Oc1ccc(F)cc1

SAL-INS-1ea6d4ee-2
0.455

View
O=C(CCl)N1CC2CC1CN2S(=O)(=O)c1ccc(Cl)s1

MAK-UNK-3f402c2b-24
0.455

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

AAR-POS-0daf6b7e-3
0.453

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-13
0.453

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1

AAR-POS-d2a4d1df-36
0.453

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

WAR-XCH-79d12f6e-6
0.453

View
Cc1noc(C)c1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-24
0.452

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc4ncoc4c3)s2)CC1

NIM-UNI-05f93fcc-8
0.450

View
O=C(CCl)N1CCN(Cc2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-2
0.450

View
O=C(CCl)N1CCC(C(=O)N2CCCN(S(=O)(=O)c3ccc(Br)s3)CC2)CC1

SAD-SAT-f2e2579e-9
0.442

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAR-TRE-6a44bbf2-31
0.441

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAR-TRE-6a44bbf2-49
0.441

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAK-UNK-7c9d1431-5
0.441

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAK-UNK-7c9d1431-7
0.441

View
CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

TAT-ENA-80bfd3e5-43
0.439

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-37
0.439

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-7
0.439

View
CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-65
0.439

View
COS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-9
0.439

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1OC

MAK-UNK-7c9d1431-19
0.439

View
CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-11
0.439

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC3OCOC3C=C2)CC1

SAD-SAT-bc31ec01-8
0.435

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

TAT-ENA-80bfd3e5-25
0.426

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

MAK-UNK-7c9d1431-4
0.426

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1

MAK-UNK-7c9d1431-3
0.426

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1

IND-SYN-6c8299e8-2
0.426

View
CC(C#N)S(=O)(=O)Nc1ccnc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)c1

MAK-UNK-c74072e5-6
0.424

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-45
0.420

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-30
0.420

View
Nc1cc(-c2cc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)ccc2F)cs1

MAK-UNK-c74072e5-9
0.416

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

1.000

View
O=C(CCl)N1CCCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.811

View
CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.776

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O=C(CO)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.760

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NCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.745

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CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.717

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CSCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.717

View
CS(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.704

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NCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.704

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CC(=O)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.704

View
CC(C)(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.704

View
CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.700

View
NC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.700

View
CN(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

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O=C(CC(F)(F)F)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

View
O=C(CC1CC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

View
CC(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

View
N#CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

View
C=C(Cl)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

View
O=C(O)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

View
COCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

View
NOCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

View
CNCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

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CCS(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.691

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CNCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.684

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C=CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.684

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(Br)S2)CC1

0.679

View
O=C(CC1=CC=C(Cl)S1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.679

View
CC(C)(O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.679

View
CC(C)(N)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.679

View
CC(C)(C)OCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.672

View
O=C(CN1C(=O)CCC1=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.672

View
O=C(CN1CCCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CCC(=O)N1CCCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CCCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CS(=O)(=O)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
C[C@H](N)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
NCCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
C[C@@H](N)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CC(N)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
COC(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CCSCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CNS(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
C=C(C)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CC1(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)S3)CC2)CC1

0.667

View
CC(F)(F)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
O=C(CC1CCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
O=C(CCC(F)F)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CCN(CC)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.667

View
CCC(CC)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
O=C(CSC(F)F)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
C#CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
O=C(CO)N1CCCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CC(C)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
COCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CC(=O)NCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CC(=O)CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
O=C(CCC(F)(F)F)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
NC(=O)CSCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CC(C)S(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CC(C)(C)CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CN(C)C(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CC(C)(C)S(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
O=C(CCCCO)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CCOCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CSCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
NC(=O)CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CC(=O)OCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
O=C(O)CCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
O=C(O)CCCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
CCNCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.655

View
O=C(CN1CCSSCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.650

View
O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1)N1CCOCC1

0.644

View
O=C(CN1CCCCCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
O=C(O)COCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
NCC(=O)N1CCCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
CCCCCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
CC(C)OCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
O=C(CCC1CC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
CCN(CC)S(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
O=C(CC1CCCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
CCC(C)(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
O=C(CSC1CC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
O=C(CN1C2CCC1CC2)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.644

View
O=C(CN1CCNCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.639

View
O=C(CC1=C(Cl)C=CC=C1Cl)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.633

View
O=C(CCC1=CC=C(Cl)S1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.633

View
O=C(CC1=CC=CC=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.633

View
O=C(CC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.633

View
O=C(CN1CCCCCCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.633

View
O=C1CC(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)S3)CC2)C1

0.633

View
O=C(CSCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1)N1CCCCC1

0.623

View
O=C(CN1CCSCC1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.623

View
O=C(CC1=C(F)C=CC=C1F)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.613

View
O=C(CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1)C1=CC=C(Cl)S1

0.613

View
O=C1CC(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)S3)CC2)N1

0.613

View
O=C(CC1=CC=C(F)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.613

View
CC1=CC=CC(C)=C1CC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.603

View
O=C(COC1=CC=CC=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.603

View
O=C(COC1=CC=C(Cl)C=C1)N1CCN(S(=O)(=O)C2=CC=C(Cl)S2)CC1

0.594

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

1.000

View
CSCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.717

View
CC(C)CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.691

View
COCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.691

View
OC(=O)CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.691

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.667

View
CC(=O)NCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.655

View
NC(=O)NCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.655

View
OC(=O)CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.655

View
CN(CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1)C(C)=O

0.644

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCCC1

0.644

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCCCC1

0.644

View
OC(=O)COCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.644

View
CCOC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.643

View
CC(C)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.636

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

0.636

View
CC1CC1C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.632

View
CC(C)(C)OC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.632

View
CC(CC(O)=O)CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.623

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)Cc1ccoc1

0.623

View
CCNC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.621

View
CC1CC1C(=O)NCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.619

View
CCCNC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.617

View
CCC(C)(C)NCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.613

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCC1

0.603

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CCC1CCCC1

0.603

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CC1CCC=C1 |c:23|

0.603

View
CCCCNC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.597

View
Cc1ccccc1CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.594

View
CCc1ccc(CCC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)cc1

0.594

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CSc1ncccn1

0.594

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccccc1

0.593

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)NCC=C

0.590

View
OC(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.589

View
CC(=O)N1CCCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.586

View
Cc1ccc(CCC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)cc1

0.585

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CSC1=NCCS1 |t:21|

0.585

View
COc1ccc(CC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)cc1

0.585

View
FC(F)(F)c1ccc(CC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)cc1

0.585

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCCC1

0.583

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccncc1

0.583

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC(=O)N2CCCCC2)CC1

0.581

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC(=O)N2CCCCCC2)CC1

0.581

View
CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.577

View
CS(=O)(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.577

View
CC(C)CNC(=O)NCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.576

View
COc1ccc(OCC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)cc1

0.576

View
CCN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.574

View
Cc1ccc(cc1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.574

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)C12CC3CC(CC(C3)C1)C2

0.574

View
CCCCCN(CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1)C(C)C

0.574

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1cccs1

0.571

View
CC1CCCCN1CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.567

View
COc1ccc(CCC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)cc1

0.567

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCCCC1

0.565

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CCC1CCOC1

0.559

View
OC12CC3CC(C1)CC(CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1)(C3)C2

0.559

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC(=O)N2CCOCC2)CC1

0.554

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCCCC1=O

0.551

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CNC(=O)C1CCCCC1

0.551

View
CCc1ccc(C=CC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)cc1 |w:6.5|

0.551

View
Clc1ccc(s1)S(=O)(=O)N1CCNCC1

0.547

View
CC(=O)N1CCC(CC1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.547

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccc(cc1)C#N

0.547

View
NC(=O)NC(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.540

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCCO1

0.538

View
Cl.Clc1ccc(s1)S(=O)(=O)N1CCNCC1

0.537

View
CN(CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1)Cc1ccsc1

0.535

View
Cc1cccc(c1)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.530

View
CCC(C)(C)NC(C)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.529

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)S(=O)(=O)c1cccs1

0.526

View
CC(C)N(C(C)C)C(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.524

View
COC(=O)CCN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.524

View
Cc1cccc(C=CC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)c1 |w:6.5|

0.521

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CN(Cc1ccccc1)C1CC1

0.521

View
CCCNC(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.515

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CCC#N)CC1

0.508

View
Clc1ccc(s1)S(=O)(=O)N1CCN(Cc2ccccc2)CC1

0.508

View
CC(C)CNC(=O)C(C)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.508

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)C(=O)CNC(=O)Cc1cccc2ccccc12

0.506

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC1)c1ccccc1

0.500

View
Fc1ccc(cc1)N1CCN(CC1)C(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.500

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC(=O)NCC=C)CC1

0.493

View
CC(N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1)C(=O)N1CCOCC1

0.471

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CCc2ccccc2)CC1

0.470

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC(=O)NC2CCCCC2)CC1

0.458

View
CC(N1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1)C(=O)N1CCN(Cc2ccccc2)CC1

0.449

View
Clc1ccc(s1)S(=O)(=O)N1CCN(CC(=O)NCC2CCCCC2)CC1

0.446

View
CC1CCC(CC1)NC(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.446

View
Clc1ccc(s1)S(=O)(=O)N1CCNC(=O)C1

0.426

View
CC1COCCN1CCN1CCN(CC1)S(=O)(=O)c1ccc(Cl)s1

0.425

View
CC1CN(CCN2CCN(CC2)S(=O)(=O)c2ccc(Cl)s2)CCO1

0.425

View
CN(CC(=O)N1CCN(CC1)C(=O)C1CC1)S(=O)(=O)c1ccc(Cl)s1

0.365

View
[#6]\[#6](-[#6])=[#6]/[#6]-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)c1ccc(Cl)s1

0.364

View
CN(CC(=O)N1CCN(CC(=O)NC2CC2)CC1)S(=O)(=O)c1ccc(Cl)s1

0.325

View
CN(C)C(=O)CN(C)S(=O)(=O)c1ccc(Cl)s1

0.312

View
Clc1ccc(s1)S(=O)(=O)NCCN1C(=O)CCC1=O

0.304

View
CN(CCN1CCCC1)S(=O)(=O)c1ccc(Cl)s1

0.300

View
CCNC(=O)CN(C)S(=O)(=O)c1ccc(Cl)s1

0.290

View
CNC(=O)CNC(=O)CN(C)S(=O)(=O)c1ccc(Cl)s1

0.270

View
C(N1CCN(S(C)(=O)=O)CC1)(=O)C1CCN(S(C2SC(Cl)=CC=2)(=O)=O)CC1

0.729

View
C(NCCN1CCN(S(C)(=O)=O)CC1)(=O)C1CCN(S(C2SC(Cl)=CC=2)(=O)=O)CC1

0.709

View
C(N1CCN(S(CC)(=O)=O)CC1)(=O)C1CCN(S(C2SC(Cl)=CC=2)(=O)=O)CC1

0.708

View
C(N1CCN(S(C)(=O)=O)CC1)(=O)C1CN(S(C2SC(Cl)=CC=2)(=O)=O)CCC1

0.707

View


Discussion: