Molecule Details

Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1
piperazine-chloroacetamide Enamine Mcule MolPort
View on Fragalysis x0731
Molecular Properties
SMILES:
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1
MW: 316.81
Fraction sp3: 0.46
HBA: 3
HBD: 0
Rotatable Bonds: 3
TPSA: 57.69
cLogP: 1.06672
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-08171
Enamine SCR: Z55928785
Enamine REAL: Z55928785
Mcule: MCULE-1213384460
MolPort: MolPort-002-465-803

Hetero_hetero

Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27
1.000

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CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-13
0.712

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CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-78
0.712

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

AAR-POS-d2a4d1df-44
0.706

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

MAR-TRE-6a44bbf2-58
0.692

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

KAY-MCD-d0fe5261-1
0.692

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COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-17
0.685

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(C3CC3)cc2)CC1

MAK-UNK-c74072e5-8
0.655

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1

MAK-UNK-7c9d1431-6
0.655

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAR-TRE-6a44bbf2-21
0.654

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAK-UNK-7c9d1431-9
0.654

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CCOc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-22
0.649

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-7c9d1431-8
0.625

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAR-TRE-6a44bbf2-26
0.625

View
Cc1ccc(S(=O)(=O)N2CCCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-9a6c5cf3-2
0.612

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O=C(CCl)N1CCN(S(=O)(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-2
0.600

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

MAR-TRE-6a44bbf2-32
0.586

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

ABB-MCD-f8003a30-1
0.586

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O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)CC1

MAT-POS-ee51dedd-2
0.571

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CC(=O)Nc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc(C)cc3)CC2)cc1

MAT-POS-b5746674-55
0.564

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(Cl)c2)CC1

MAK-UNK-7c9d1431-10
0.559

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COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1OC

MAK-UNK-7c9d1431-19
0.557

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Cc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-11
0.556

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O=C(CCl)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1

SAD-SAT-bc31ec01-5
0.554

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

AAR-POS-d2a4d1df-23
0.552

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

MAR-TRE-6a44bbf2-18
0.552

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

LON-WEI-8f408cad-4
0.552

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1

AAR-POS-d2a4d1df-36
0.550

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Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

AAR-POS-0daf6b7e-3
0.550

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Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-13
0.550

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Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

WAR-XCH-79d12f6e-6
0.550

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CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

TAT-ENA-80bfd3e5-43
0.532

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CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-65
0.532

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CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-11
0.532

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAR-TRE-6a44bbf2-31
0.531

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAK-UNK-7c9d1431-7
0.531

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAR-TRE-6a44bbf2-49
0.531

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAK-UNK-7c9d1431-5
0.531

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Cc1ccc(S(=O)(=O)N2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)cc1

MAT-POS-b5746674-57
0.528

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CS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-7
0.525

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NS(=O)(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-f2e2579e-5
0.522

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O=C(CCl)N1CCN(S(=O)(=O)C2=CCC=C2)CC1

SAD-SAT-3a925b8b-9
0.517

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O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=C2)CC1

MAK-UNK-d4768348-1
0.517

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O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=N2)CC1

MAK-UNK-d4768348-4
0.517

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)n3ccnc3)CC2)cc1

SAD-SAT-2fd372d1-9
0.516

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

MAK-UNK-7c9d1431-4
0.516

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

TAT-ENA-80bfd3e5-25
0.516

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1

MAK-UNK-7c9d1431-3
0.516

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O=C(CCl)N1CCN(S(=O)(=O)C2=CCN=C2)CC1

MAK-UNK-d4768348-5
0.508

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O=C(CCl)N1CCN(S(=O)(=O)C2=CCS(O)=C2)CC1

MAK-UNK-d4768348-8
0.508

View
O=C(CCl)N1CCN(S(=O)(=O)c2cpcc(Cl)c2)CC1

SAD-SAT-bc31ec01-4
0.508

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1

MAR-TRE-6a44bbf2-38
0.500

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1

MAK-UNK-7c9d1431-1
0.500

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cc3cccc4ccccc34)cc2)CC1

MED-COV-4280ac29-5
0.493

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1

IND-SYN-6c8299e8-2
0.492

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O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

MAR-TRE-6a44bbf2-52
0.492

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-15
0.492

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

AAR-POS-d2a4d1df-22
0.492

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3
0.492

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)N(C)Cc3cc(C)on3)CC2)cc1

SIM-SYN-3099a863-2
0.486

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O=C(CCl)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccc([N+](=O)[O-])cc3)CC2)CC1

SAD-SAT-9a6c5cf3-5
0.486

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)CC1

MAR-TRE-6a44bbf2-36
0.485

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)CC1

MAK-UNK-7c9d1431-2
0.485

View
COS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-9
0.484

View
O=C(CCl)N1CCN(S(=O)(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-3
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

MAR-TRE-6a44bbf2-4
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Br)s2)CC1

NIM-UNI-05f93fcc-1
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

LON-WEI-8f408cad-2
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

AAR-POS-d2a4d1df-32
0.483

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CN[SH]=C2)CC1

MAK-UNK-d4768348-2
0.483

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1

MAK-UNK-7c9d1431-12
0.483

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)N(C)Cc3cccnc3)CC2)cc1

SIM-SYN-3099a863-3
0.479

View
N#Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-f2e2579e-10
0.479

View
Cc1cc(C)cc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)c1

NIM-UNI-05f93fcc-7
0.478

View
Cc1ccc(S(=O)(=O)NC2CCN(C(=O)CCl)CC2)cc1

WAR-XCH-79d12f6e-4
0.476

View
Cc1noc(C)c1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-24
0.475

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CN(C)S(=O)(=O)c3ccc4c(c3)OCCO4)CC2)cc1

MAR-LAB-ff9967db-22
0.474

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Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AHN-SAT-de2502ba-8
0.474

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-25
0.474

View
Cc1ccc(S(=O)(=O)N2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-3f402c2b-5
0.469

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

MAR-TRE-6a44bbf2-8
0.468

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

AAR-POS-d2a4d1df-34
0.468

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-45
0.463

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-30
0.463

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C(Cl)CC=C2)CC1

SAD-SAT-3a925b8b-6
0.459

View
O=C(CCl)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccc(C4CCCCC4)cc3)CC2)CC1

SAD-SAT-9a6c5cf3-9
0.453

View
O=C(CCl)N1CCN(S(=O)(=O)C2=NC[SH]=C2)CC1

MAK-UNK-d4768348-3
0.452

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc(O)cc3)s2)CC1

NIM-UNI-05f93fcc-14
0.449

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cccc(F)c2)CC1

BEN-DND-76ad4ac9-14
0.448

View
Cc1ccc(NC(=O)CN2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-12
0.444

View
COc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-15
0.444

View
Cc1ccc(NCc2ccccc2)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

NAU-LAT-f723e322-5
0.440

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-37
0.439

View
Cc1cc(CN2CCN(C(=O)CCl)CC2)cc(S(N)(=O)=O)c1

SAD-SAT-581007d4-4
0.439

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-7
0.439

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C3CC3[SH]=C2)CC1

SAD-SAT-3a925b8b-7
0.438

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccccc3)s2)CC1

NIM-UNI-05f93fcc-2
0.435

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC3OCOC3C=C2)CC1

SAD-SAT-bc31ec01-8
0.435

View
Nc1cc(-c2cc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)ccc2F)cs1

MAK-UNK-c74072e5-9
0.434

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4ccc(Cl)cc34)CC2)cc1

MAT-POS-590ac91e-66
0.430

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CCl)CC2)C=C1

0.792

View
CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2)CC1

0.740

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CO)CC2)C=C1

0.740

View
CC(=O)C1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.712

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2)CC1

0.706

View
CC(C)(C)C1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.698

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCC3)CC2)C=C1

0.698

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(Br)C=C2)CC1

0.692

View
CC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2)CC1

0.688

View
CC(C)C1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.685

View
COC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.685

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCCC3)CC2)C=C1

0.685

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CN(C)C)CC2)C=C1

0.685

View
COCC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2)CC1

0.685

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC(C)C)CC2)C=C1

0.685

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.673

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(S(C)(=O)=O)CC3)CC2)C=C1

0.673

View
CC(=O)N1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.673

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCS(=O)(=O)CC3)CC2)C=C1

0.667

View
CCCC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.661

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(C)CC3)CC2)C=C1

0.661

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCCCCC3)CC2)C=C1

0.661

View
CCC(=O)N1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.661

View
CCOC(=O)C1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.655

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CN3C(=O)CCC3=O)CC2)C=C1

0.655

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(C(C)C)CC3)CC2)C=C1

0.655

View
N#CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.655

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=CC=C2)CC1

0.654

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCCCCCC3)CC2)C=C1

0.649

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CN3CCCC3)CC2)C=C1

0.649

View
CCN(CC)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2)CC1

0.649

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CC(C)C3)CC2)C=C1

0.649

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CC=CC3)CC2)C=C1

0.638

View
CCC(C)C1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.638

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCOCC3)CC2)C=C1

0.638

View
C=C1CN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)C1

0.638

View
CCN1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.638

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCC(C)CC3)CC2)C=C1

0.638

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC=C(Cl)C=C3)CC2)C=C1

0.633

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCSCC3)CC2)C=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCC(=O)CC3)CC2)C=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC=CC=C3)CC2)C=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(C(C)(C)C)CC3)CC2)C=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCC(C)(C)CC3)CC2)C=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCC4(CC3)CC4)CC2)C=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N(C)C)CC2)C=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1C

0.625

View
CC1=CC=C(S(=O)(=O)CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.623

View
CCC(=O)N1CCCN(S(=O)(=O)C2=CC=C(C)C=C2)CC1

0.621

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CO)CC2)C=C1

0.621

View
CC1=CC=C(OCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.617

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(C(=O)CN(C)C)CC3)CC2)C=C1

0.617

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCS(=O)CC3)CC2)C=C1

0.617

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(C(=O)C(C)(C)C)CC3)CC2)C=C1

0.617

View
COCC(=O)N1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.617

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(C(=O)C(C)C)CC3)CC2)C=C1

0.617

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(C(=O)CC(C)C)CC3)CC2)C=C1

0.617

View
COC(=O)N1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.617

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CC(F)C3)CC2)C=C1

0.617

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCN(C(=O)N(C)C)CC3)CC2)C=C1

0.617

View
C=C1CCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.617

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CN)CC2)C=C1

0.610

View
CSCC(=O)N1CCCN(S(=O)(=O)C2=CC=C(C)C=C2)CC1

0.600

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC(=O)N3CCSC3)CC2)C=C1

0.597

View
CC(=O)N1CCCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.597

View
CCC(=O)N1CCCN(C(=O)CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.597

View
CCCC(=O)N1CCCN(S(=O)(=O)C2=CC=C(C)C=C2)CC1

0.590

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CS(C)(=O)=O)CC2)C=C1

0.590

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)N3CCN(S(C)(=O)=O)CC3)CC2)C=C1

0.590

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(Cl)C(Cl)=C2)CC1

0.589

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(CCCl)C=C3)CC2)C=C1

0.587

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.581

View
CC1=CC=C(S(=O)(=O)CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3)CC2)C=C1

0.581

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CN(C)C)CC2)C=C1

0.581

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(S(N)(=O)=O)C=C3)CC2)C=C1

0.581

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)N3CCN(CC(=O)N4CCCC4)CC3)CC2)C=C1

0.574

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)N3CCN(C(=O)CN4CCCC4)CC3)CC2)C=C1

0.574

View
CC1=CC=C(CC(=O)N2CCCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)C=C1

0.571

View
CCC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC=C(C)C=C3)CC2)C=C1

0.565

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(S(C)(=O)=O)C=C3)CC2)C=C1

0.565

View
COC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CCl)CC2)C=C1

0.565

View
CC(=O)N1CCN(C(=O)CN2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.565

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(CCCCl)C=C3)CC2)C=C1

0.561

View
O=C(CCl)N1CCCN(S(=O)(=O)C2=CC=C(F)C=C2)CC1

0.557

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(F)C=C3)CC2)C=C1

0.556

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)N3CCN(CC(=O)N4CCCCC4)CC3)CC2)C=C1

0.556

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(I)C=C3)CC2)C=C1

0.556

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(N)C=C3)CC2)C=C1

0.556

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(S(=O)(=O)F)C=C3)CC2)C=C1

0.556

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)N3CCN(C)CC3)CC2)C=C1

0.556

View
CCN1CCN(C(=O)CN2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.556

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Br)C=C3)CC2)C=C1

0.556

View
CCC(=O)N1CCN(C(=O)CN2CCN(S(=O)(=O)C3=CC=C(C)C=C3)CC2)CC1

0.556

View
CC1=CC=C(S(=O)(=O)NCC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.552

View
CC1=CC=C(C)C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=C1

0.550

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CC3=C(Cl)C=CC=C3Cl)CC2)C=C1

0.544

View
CC1=CC=C(OCC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3)CC2)C=C1

0.537

View
O=C(CCl)N1CCCN(S(=O)(=O)C2=CC=CC=C2)CC1

0.533

View
CC1=CC=C(OCC(=O)N2CCN(S(=O)(=O)C3=CC=C(CCCl)C=C3)CC2)C=C1

0.521

View
CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CCl)CC1

0.517

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

1.000

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.740

View
CC(=O)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.712

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(Cl)cc1

0.706

View
CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.698

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CC(C)(C)C

0.698

View
Fc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.692

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.688

View
CC(C)CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.685

View
CCCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.661

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1

0.654

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNC(N)=O

0.649

View
CSCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.649

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCC1

0.649

View
CN(CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1)C(C)=O

0.638

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCCC1

0.627

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCCCC1

0.627

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)Cc1ccccc1

0.627

View
Cc1ccc(cc1C)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.625

View
CC(Cl)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.618

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNC1CC1

0.617

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C(C)(C)C

0.611

View
CC(C)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.611

View
CCC(CC)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.596

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

0.589

View
CC1CCN(CC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(C)cc2)CC1

0.587

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC(N)=O)CC1

0.571

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCC1

0.569

View
CN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.560

View
Fc1cccc(c1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.552

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.550

View
Cc1ccc(C)c(c1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.550

View
Cl.CN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.549

View
CCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.547

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(CC)cc1

0.517

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc2ccccc2c1

0.516

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(C)=O

0.509

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(O)=O

0.509

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(C)(C)C

0.508

View
CCCC(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.500

View
CC(C)C(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.500

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(C)C

0.500

View
Cl.CCCC(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.493

View
CCC(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.492

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CCNC(=O)C(C)(C)C)CC1

0.492

View
CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(CC)cc1

0.492

View
CCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.491

View
CCC(CC)C(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.485

View
CCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CC(C)(C)C

0.484

View
CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(C)(C)C

0.484

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1Cl

0.483

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1

0.483

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(CC(C)C)cc1

0.476

View
CCC(C)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CC

0.476

View
CCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CC(C)C

0.476

View
CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(C)C

0.476

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(C)(C)C

0.474

View
Cl.Cc1ccc(cc1)S(=O)(=O)N1CCN(CCNC(=O)C2CC2)CC1

0.471

View
CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C#N

0.469

View
CC(C)(C)CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C#N

0.469

View
CCCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(CC)cc1

0.469

View
CC(=O)NCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.468

View
Fc1ccccc1S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.468

View
CNC(=O)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.467

View
CC(C)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.466

View
Cl.COCC(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.464

View
CN(C)CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(F)(F)F

0.462

View
Cc1ccc(cc1)S(=O)(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.462

View
CC(C)Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.459

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C#N

0.458

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(F)(F)F

0.458

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)c(Cl)c1

0.458

View
CCC(C)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.452

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1

0.446

View
CCCCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.444

View
CCN1CCN(CC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(cc2)C(C)(C)C)CC1

0.441

View
CCC(C)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CN(C)C

0.441

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1C#N

0.439

View
CCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C(C)(C)C

0.435

View
CCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C(C)C

0.435

View
CC(C)N(C)CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(F)(F)F

0.435

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)c(C)c1

0.433

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)c(F)c1

0.419

View
CCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

0.415

View
CCC(C)(C)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C#N

0.412

View
CC(Cl)C(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1

0.397

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.381

View
CCN(CC(=O)N1CCN(CC)CC1)S(=O)(=O)c1ccc(C)cc1

0.371

View
CN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c1ccc(C)cc1

0.368

View
CCC(=O)N1CCN(CCNS(=O)(=O)c2ccc(C)cc2)CC1

0.366

View
CCN1CCN(CC1)C(=O)CN(C)S(=O)(=O)c1ccc(C)cc1

0.357

View
CC(=O)N1CCN(CCNS(=O)(=O)c2ccc(C)cc2)CC1

0.353

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.339

View
CC(=O)NCC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.338

View
CCN(CC)C(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(cc1)C#N

0.329

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)C(C)(C)C

0.319

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC(=O)N2CCN(CC2)S(C)(=O)=O)CC1

0.307

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)C(C)(C)C

0.294

View
CC(=O)N1CCN(CCNS(=O)(=O)c2ccc(cc2)C#N)CC1

0.231

View
[#6]\[#6](-[#6])=[#6]/[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)c1ccc(-[#6])cc1

0.187

View
N1(S(=O)(=O)C2C=CC(C)=CC=2)CCN(C(C)=O)CC1

0.954

View
C(N1CCN(S(C2=CC=C(C)C=C2)(=O)=O)CC1)(C(Cl)Cl)=O

0.950

View
N1(S(=O)(=O)C2C=CC(CC)=CC=2)CCN(C(C)=O)CC1

0.929

View
N1(S(=O)(=O)C2C=CC(C#N)=CC=2)CCN(C(C)=O)CC1

0.920

View
C(N1CCN(S(C2=CC=C(C)C=C2)(=O)=O)CC1)(=O)CC

0.918

View

Discussion: