Molecule Details

Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1
piperazine-chloroacetamide Enamine Mcule MolPort
View on Fragalysis x0771
Molecular Properties
SMILES:
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1
MW: 330.837
Fraction sp3: 0.5
HBA: 3
HBD: 0
Rotatable Bonds: 3
TPSA: 57.69
cLogP: 1.37514
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-17538
Enamine SCR: Z56949588
Enamine REAL: Z56949588
Mcule: MCULE-2516335004
MolPort: MolPort-002-470-400

Hetero_hetero

Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

AAR-POS-0daf6b7e-3
0.661

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-13
0.661

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

WAR-XCH-79d12f6e-6
0.661

View
C=CC(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2C)CC1

JAN-GHE-4287bd1a-1
0.644

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27
0.550

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-68
0.550

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAR-TRE-6a44bbf2-26
0.524

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-7c9d1431-8
0.524

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1

MAK-UNK-7c9d1431-12
0.516

View
Cc1ccc(S(=O)(=O)N2CC3CC2CN3C(=O)CCl)c(C)c1

MAK-UNK-3f402c2b-12
0.507

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Cc1ccc(NCc2ccccc2)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

NAU-LAT-f723e322-5
0.507

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

MAR-TRE-6a44bbf2-8
0.500

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

AAR-POS-d2a4d1df-34
0.500

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-45
0.493

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-30
0.493

View
CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

TAT-ENA-80bfd3e5-43
0.493

View
CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-65
0.493

View
CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-11
0.493

View
CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-13
0.492

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CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-78
0.492

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Cc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-11
0.471

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N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-7
0.471

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-37
0.471

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

MAR-TRE-6a44bbf2-32
0.470

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

ABB-MCD-f8003a30-1
0.470

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAR-TRE-6a44bbf2-21
0.468

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAK-UNK-7c9d1431-9
0.468

View
Cc1cc(C)cc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)c1

NIM-UNI-05f93fcc-7
0.466

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

MAR-TRE-6a44bbf2-18
0.462

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

LON-WEI-8f408cad-4
0.462

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

AAR-POS-d2a4d1df-23
0.462

View
O=C(CCl)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1

SAD-SAT-bc31ec01-5
0.460

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

AAR-POS-d2a4d1df-44
0.460

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4ccc(F)cc34)CC2)c(C)c1

MAT-POS-590ac91e-64
0.458

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-17
0.455

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

MAR-TRE-6a44bbf2-58
0.453

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)CC1

MAT-POS-ee51dedd-2
0.453

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

KAY-MCD-d0fe5261-1
0.453

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O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

MAR-TRE-6a44bbf2-52
0.453

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3
0.453

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-2
0.453

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-15
0.453

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

AAR-POS-d2a4d1df-22
0.453

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=C2)CC1

MAK-UNK-d4768348-1
0.453

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4cc(F)ccc34)CC2)c(C)c1

MAT-POS-590ac91e-63
0.452

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1OC

MAK-UNK-7c9d1431-19
0.449

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(Cl)c2)CC1

MAK-UNK-7c9d1431-10
0.448

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

AAR-POS-d2a4d1df-32
0.446

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

LON-WEI-8f408cad-2
0.446

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Br)s2)CC1

NIM-UNI-05f93fcc-1
0.446

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

MAR-TRE-6a44bbf2-4
0.446

View
Cc1noc(C)c1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-24
0.439

View
CS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-7
0.439

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cc(F)ccc2F)CC1

BEN-DND-76ad4ac9-10
0.438

View
CCOc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-22
0.435

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(C3CC3)cc2)CC1

MAK-UNK-c74072e5-8
0.433

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1

MAK-UNK-7c9d1431-6
0.433

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCC=C2)CC1

SAD-SAT-3a925b8b-9
0.431

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=N2)CC1

MAK-UNK-d4768348-4
0.431

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAR-TRE-6a44bbf2-31
0.431

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAK-UNK-7c9d1431-5
0.431

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAK-UNK-7c9d1431-7
0.431

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAR-TRE-6a44bbf2-49
0.431

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C3CC3[SH]=C2)CC1

SAD-SAT-3a925b8b-7
0.426

View
O=C(CCl)N1CCN(S(=O)(=O)c2cpcc(Cl)c2)CC1

SAD-SAT-bc31ec01-4
0.426

View
Cc1ccc(S(C)(=O)=O)cc1S(=O)(=O)N1CCN(C(=O)C2CCN(C(=O)CCl)CC2)CC1

SAD-SAT-9a6c5cf3-7
0.425

View
O=C(CCl)N1CCN(S(=O)(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-3
0.424

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C(Cl)CC=C2)CC1

SAD-SAT-3a925b8b-6
0.424

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CN[SH]=C2)CC1

MAK-UNK-d4768348-2
0.424

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCN=C2)CC1

MAK-UNK-d4768348-5
0.424

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCS(O)=C2)CC1

MAK-UNK-d4768348-8
0.424

View
O=C(CCl)N1CCN(S(=O)(=O)C2=NC[SH]=C2)CC1

MAK-UNK-d4768348-3
0.418

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

TAT-ENA-80bfd3e5-25
0.417

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

MAK-UNK-7c9d1431-4
0.417

View
O=C(CCl)N1CCCN(S(=O)(=O)c2ccccc2F)CC1

BEN-DND-76ad4ac9-11
0.417

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1

MAK-UNK-7c9d1431-3
0.417

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1

IND-SYN-6c8299e8-2
0.417

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cccc(F)c2)CC1

BEN-DND-76ad4ac9-14
0.417

View
COS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-9
0.408

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1

MAK-UNK-7c9d1431-1
0.405

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCO3)CC1

MAR-TRE-6a44bbf2-38
0.405

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccccc3)s2)CC1

NIM-UNI-05f93fcc-2
0.405

View
O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAK-UNK-7c9d1431-23
0.403

View
O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAR-TRE-6a44bbf2-28
0.403

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.403

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cccs2)CC1

BEN-DND-76ad4ac9-13
0.403

View
O=C(CCl)N1CCCN(S(=O)(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-12
0.403

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc(O)cc3)s2)CC1

NIM-UNI-05f93fcc-14
0.400

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccncc3)s2)CC1

NIM-UNI-310206f0-69
0.400

View
COc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-15
0.397

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3cccnc3)s2)CC1

NIM-UNI-05f93fcc-6
0.397

View
Cc1ccc(S(=O)(=O)N2CCCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-9a6c5cf3-2
0.395

View
N#Cc1c(F)cccc1-c1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

SAD-SAT-bc31ec01-10
0.395

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)CC1

MAR-TRE-6a44bbf2-36
0.395

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)CC1

MAK-UNK-7c9d1431-2
0.395

View
Cc1cccc(N2CCN(C(=O)CCl)CC2)c1

SAD-SAT-5b1897b2-4
0.394

View
O=C(CCl)N1CCN(S(=O)(=O)/C=C/c2ccccc2)CC1

MAK-UNK-7c9d1431-27
0.391

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-25
0.391

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AHN-SAT-de2502ba-8
0.391

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3cncnc3)s2)CC1

NIM-UNI-310206f0-67
0.390

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CO)CC2)C(C)=C1

0.778

View
CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.764

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CN(C)C)CC2)C(C)=C1

0.712

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC(C)C)CC2)C(C)=C1

0.712

View
COCC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.712

View
CC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.704

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CN3C(=O)CCC3=O)CC2)C(C)=C1

0.694

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CN3CCCC3)CC2)C(C)=C1

0.677

View
CCN(CC)CC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.677

View
CCC(=O)N1CCCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.672

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)C=C1

0.667

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C(=O)O)CC2)C(C)=C1

0.667

View
CC1=CC=C(C)C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=C1

0.661

View
CC1=CC=C(S(=O)(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)C(C)=C1

0.660

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C(C)(C)C)CC2)C(C)=C1

0.655

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC=C(Cl)C=C3)CC2)C(C)=C1

0.652

View
CCOC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.650

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC=CC=C3)CC2)C(C)=C1

0.646

View
COC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.644

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C(C)C)CC2)C(C)=C1

0.644

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)N(C)C)CC2)C(C)=C1

0.644

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC=CC=C3Cl)CC2)C(C)=C1

0.642

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC=CC=C3F)CC2)C(C)=C1

0.642

View
CCN(CC)C(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.639

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)OC(C)(C)C)CC2)C(C)=C1

0.639

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3CCCCC3)CC2)C(C)=C1

0.636

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C(=O)N3CCCC3)CC2)C(C)=C1

0.633

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C(C)O)CC2)C(C)=C1

0.633

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)N3CCNCC3)CC2)C(C)=C1

0.629

View
CCNC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.629

View
CCC(CC)C(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.629

View
CCOC(=O)C(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.629

View
CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CCl)CC1

0.627

View
CC1=CC=C(OCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)C=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CN3CCOCC3)CC2)C(C)=C1

0.627

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)N3CCCC3)CC2)C(C)=C1

0.623

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C3CC3)CC2)C(C)=C1

0.623

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC=CS3)CC2)C(C)=C1

0.618

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCC3CCCC3)CC2)C(C)=C1

0.618

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(N)=O)CC2)C(C)=C1

0.613

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)NC(C)(C)C)CC2)C(C)=C1

0.613

View
CC(=O)N1CCCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.607

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)N3CCCCC3)CC2)C(C)=C1

0.603

View
CC1=CC=C(C(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)C=C1

0.603

View
COC(OC)C(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.603

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)N3CCCC3)CC2)C(C)=C1

0.600

View
CCS(=O)(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.596

View
CC(=O)NCC(=O)N1CCCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.594

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)N3CCOCC3)CC2)C(C)=C1

0.594

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)COC3=CC=C(F)C=C3)CC2)C(C)=C1

0.592

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CC3=CC(F)=CC=C3)CC2)C(C)=C1

0.592

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCCC3=CC=CC=C3)CC2)C(C)=C1

0.592

View
COC1=CC=C(CCC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)C=C1

0.592

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C3=C(Cl)C=CC=C3Cl)CC2)C(C)=C1

0.591

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C3=CC=C(Cl)C=C3)CC2)C(C)=C1

0.591

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C3=CC(Cl)=CC(Cl)=C3)CC2)C(C)=C1

0.591

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)O)CC2)C(C)=C1

0.590

View
CC1=CC=C(S(=O)(=O)N2CCN(C)CC2)C(C)=C1

0.589

View
CC1=CC=C(S(=O)(=O)N2CCN(S(C)(=O)=O)CC2)C(C)=C1

0.589

View
CCN1CCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.586

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CC3CCCC3)CC2)C(C)=C1

0.586

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C3=CC=CC=C3)CC2)C(C)=C1

0.585

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C(=O)N3CCOCC3)CC2)C(C)=C1

0.585

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)N3CCCCCC3)CC2)C(C)=C1

0.582

View
CC1=CC=C(S(=O)(=O)N2CCN(CC(=O)N3CCCCC3)CC2)C(C)=C1

0.582

View
CC1=CC=C(S(=O)(=O)N2CCN(S(=O)(=O)CBr)CC2)C(C)=C1

0.576

View
CCC1=CC=C(C(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)C=C1

0.574

View
CC1=CC=C(S(=O)(=O)N2CCCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)C(C)=C1

0.571

View
COC1=CC=CC(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)=C1

0.568

View
CC1=CC=C(NC(=O)N2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)C=C1

0.567

View
CCOC(=O)N1CCCN(S(=O)(=O)C2=CC=C(C)C=C2C)CC1

0.567

View
CC1=CC=C(S(=O)(=O)N2CCN(S(=O)(=O)C3=CC(C)=CC=C3C)CC2)C(C)=C1

0.567

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C3=CC=C(Cl)C=C3Cl)CC2)C(C)=C1

0.565

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)C3=CC=CS3)CC2)C(C)=C1

0.559

View
CC1=CC(Cl)=CC=C1S(=O)(=O)N1CCN(C(=O)CO)CC1

0.556

View
CC1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=C(C)S1

0.548

View
CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(Cl)C=C2C)CC1

0.547

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CCC3=CC=CC=C3)CC2)C(C)=C1

0.547

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CO)CC2)C(Cl)=C1

0.540

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=C(F)C=C2F)CC1

0.540

View
CC1=CC=C(S(=O)(=O)N2CCC(CC(=O)N3CCCC3)CC2)C(C)=C1

0.536

View
CC1=CC=C(S(=O)(=O)N2CCC(C(=O)N3CCN(C(=O)CO)CC3)CC2)C(C)=C1

0.535

View
CCC(=O)N1CCN(S(=O)(=O)C2=CC=C(C)C=C2Cl)CC1

0.531

View
CC1=CC=C(C)C(S(=O)(=O)N2CCN(C(=O)CO)CC2)=C1

0.531

View
CC1=CC=C(S(=O)(=O)N2CCCN(CC(=O)N3CCCC3)CC2)C(C)=C1

0.528

View
CCC(=O)N1CCN(C(=O)C2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)CC1

0.528

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1C

0.524

View
CCN1CCN(C(=O)CC2CCN(S(=O)(=O)C3=CC=C(C)C=C3C)CC2)CC1

0.521

View
CC1=CC(C)=C(C)C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=C1C

0.516

View
CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CN(C)C)CC2)C(Cl)=C1

0.515

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3C)CC2)C=C1

0.514

View
CCC(=O)N1CCN(S(=O)(=O)C2=CC(C)=CC=C2C)CC1

0.508

View
CC1=CC=C(C)C(S(=O)(=O)N2CCN(C(=O)CN)CC2)=C1

0.500

View
CC1=CC=C(S(=O)(=O)N2CCCN(C(=O)CCl)CC2)C=C1

0.493

View
CC1=CC=C(S(=O)(=O)N2CCN(C3=CC=CC=C3C)CC2)C(C)=C1

0.493

View
CC1=CC=C(OCC(=O)N2CCN(S(=O)(=O)C3=CC=C(Cl)C=C3C)CC2)C=C1

0.487

View
CC1=CC=C(N2CCN(C(=O)CCl)CC2)C(C)=C1

0.484

View
COC1=CC=C(S(=O)(=O)N2CCN(C(=O)COC3=CC=C(C)C=C3)CC2)C(C)=C1

0.474

View
CCOC1=CC=C(S(=O)(=O)N2CCN(C(=O)COC3=CC=C(C)C=C3)CC2)C(C)=C1

0.462

View
CC1=CC=C(C)C(S(=O)(=O)NCC(=O)N2CCN(S(=O)(=O)C3=CC(C)=CC=C3C)CC2)=C1

0.434

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

1.000

View
CC(C)CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.712

View
COCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.712

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CCC(N)=O

0.700

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCC1

0.677

View
CCOCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.677

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCCC1

0.667

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CNC(N)=O

0.667

View
Cc1ccc(C)c(c1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.661

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)C(C)(C)C

0.655

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)Cc1ccccc1

0.646

View
CC1CC1C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.639

View
CCC(C)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.629

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

0.623

View
CC1CCN(CC(=O)N2CCN(CC2)S(=O)(=O)c2ccc(C)cc2C)CC1

0.618

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CCc1ccccc1

0.618

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCC1

0.603

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)c1cc(C)cc(C)c1

0.594

View
CN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.589

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCN(Cc2ccccc2)CC1

0.589

View
CCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.586

View
Cc1ccc(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)C1CCCC1

0.585

View
CC=CC=CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C |w:1.0,3.2|

0.567

View
CCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.557

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.550

View
Cc1ccc(cc1C)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.524

View
CCC(C)NC(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.507

View
CCC(CC)NC(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.507

View
Cc1ccc(c(C)c1)S(=O)(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.500

View
CC(C)CNC(=O)CN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1C

0.500

View
CC(=O)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CCl

0.492

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1C#N

0.471

View
ClCC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1

0.468

View
CC(C)N1CCN(CC1=O)S(=O)(=O)c1ccc(C)cc1C

0.455

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CCC(O)=O

0.420

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.415

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CC(C)(C)C

0.412

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CC(C)(C)C

0.397

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.394

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CCC(=O)N1CCCCCC1

0.384

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(cc1C)C(C)(C)C

0.382

View
CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.377

View
CC(C)CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.371

View
CC(=O)NCC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.370

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)Cc1ccccc1

0.368

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1cc(Br)c(C)cc1C

0.368

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CN1CCCCC1

0.365

View
CCCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.361

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)CCc1ccccc1

0.354

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.354

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1cc(C)c(C)c(C)c1C

0.353

View
CN(CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1)C(C)=O

0.351

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1C#N

0.351

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)C(C)(C)C

0.348

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.344

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)CNC1CC1

0.342

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC(=O)N2CCN(CC2)S(C)(=O)=O)CC1

0.338

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C(C)(C)C

0.333

View
CCC(C)C(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.329

View
CCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(CC)cc1

0.329

View
CC(Cl)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.324

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(cc1C)C(C)(C)C

0.324

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

0.319

View
CCCC(C)C(=O)N1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.316

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC1)C(=O)c1ccccc1

0.316

View
CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(CC)cc1

0.315

View
CC(C)C(=O)N1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.314

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(C)=O

0.313

View
Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(=O)C1CC1

0.306

View
CCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C#N

0.303

View
CCCCC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(CC)cc1

0.303

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1C#N

0.301

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1c(C)c(C)c(C)c(C)c1C

0.292

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(C)(C)C

0.290

View
CCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.286

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CCO)CC1

0.278

View
CN(C)C(=O)CN1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.276

View
CCN1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.275

View
CC(Cl)C(=O)N1CCN(CC1)S(=O)(=O)c1ccccc1

0.274

View
CC(=O)N1CCN(CCNS(=O)(=O)c2c(C)cc(C)cc2C)CC1

0.273

View
CC(C)Cc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.270

View
CN(CC(=O)N1CCN(C)CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.269

View
CN1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.269

View
CCCC(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.268

View
CC(C)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.268

View
CCC(C)c1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.267

View
CCN(CC)C(=O)CN1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.266

View
Cl.CCCC(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.265

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C#N

0.264

View
CC(=O)N1CCN(CC1)S(=O)(=O)c1ccc(cc1)C(F)(F)F

0.264

View
CCCN1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.264

View
CCCCc1ccc(cc1)S(=O)(=O)N1CCN(CC1)C(C)=O

0.263

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)NCCN1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.263

View
CC(C)c1cc(C(C)C)c(c(c1)C(C)C)S(=O)(=O)N1CCN(CC1)C(C)=O

0.260

View
CCC(=O)NCCN1CCN(CC1)S(=O)(=O)c1ccc(C)cc1

0.259

View
Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCN(CC(=O)NCC=C)CC1

0.256

View
CCC(CC)NC(=O)CN1CCN(CC1)S(=O)(=O)c1c(C)cc(C)cc1C

0.256

View
CC(C)N1CCN(CC1=O)S(=O)(=O)c1c(C)cc(C)cc1C

0.237

View
[#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)c1ccc(-[#6])cc1-[#6]

0.165

View
[#6]\[#6](-[#6])=[#6]\[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)S(=O)(=O)c1c(-[#6])cc(-[#6])cc1-[#6]

0.157

View
N1(S(=O)(=O)C2C=CC(C)=CC=2C)CCN(C(C)=O)CC1

0.962

View
N1(S(=O)(=O)C2C=CC(C)=CC=2C)CCN(C=O)CC1

0.925

View
N1(S(=O)(=O)C2C=CC(C)=CC=2C)CCN(CC)CC1

0.907

View
N1(S(=O)(=O)C2C=CC(C)=CC=2C)CCN(C)CC1

0.893

View
N1(S(=O)(=O)C2=C(C)C=C(C)C=C2C)CCN(C(C)=O)CC1

0.891

View

Discussion: