Molecule Details

N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1
piperazine-chloroacetamide Enamine Mcule MolPort
View on Fragalysis x0774
Molecular Properties
SMILES:
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1
MW: 327.793
Fraction sp3: 0.38
HBA: 4
HBD: 0
Rotatable Bonds: 3
TPSA: 81.48
cLogP: 0.62998
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-22719
Enamine SCR: Z147647526
Enamine REAL: Z169512080
Mcule: MCULE-1200901596
MolPort: MolPort-002-470-569

Hetero_hetero

N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-7
1.000

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N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)C2CCN(C(=O)CCl)CC2)CC1

SAD-SAT-f2e2579e-4
0.731

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1

MAK-UNK-7c9d1431-12
0.600

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

MAR-TRE-6a44bbf2-8
0.581

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

AAR-POS-d2a4d1df-34
0.581

View
N#Cc1c(F)cccc1-c1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

SAD-SAT-bc31ec01-10
0.533

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C=CC(=O)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccccc3C#N)CC2)CC1

SAD-SAT-2ceae68f-4
0.533

View
N#Cc1c(Br)cccc1-c1ccccc1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-c74072e5-4
0.519

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N#Cc1ccccc1S(=O)(=O)N1CC2CC1CN2C(=O)CCl

MAK-UNK-3f402c2b-13
0.514

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAK-UNK-7c9d1431-9
0.500

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAR-TRE-6a44bbf2-21
0.500

View
O=C(CCl)N1CCCN(S(=O)(=O)c2ccccc2F)CC1

BEN-DND-76ad4ac9-11
0.486

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

WAR-XCH-79d12f6e-6
0.471

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-13
0.471

View
N#Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-6
0.471

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)c2cc(=O)[nH]c3cc(F)ccc23)CC1

MAT-POS-590ac91e-61
0.471

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1

AAR-POS-d2a4d1df-36
0.471

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

AAR-POS-0daf6b7e-3
0.471

View
N#Cc1ccccc1CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-9
0.470

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)c2cc(=O)[nH]c3ccc(F)cc23)CC1

MAT-POS-590ac91e-62
0.465

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc([N+](=O)[O-])cc2)CC1

MAK-UNK-7c9d1431-6
0.463

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

AAR-POS-d2a4d1df-22
0.462

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-2
0.462

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

MAR-TRE-6a44bbf2-52
0.462

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3
0.462

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CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-65
0.457

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CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

TAT-ENA-80bfd3e5-43
0.457

View
CC(=O)c1cccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-11
0.457

View
O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

MAR-TRE-6a44bbf2-4
0.455

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O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

LON-WEI-8f408cad-2
0.455

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O=C(CCl)N1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

AAR-POS-d2a4d1df-32
0.455

View
CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-78
0.455

View
CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-13
0.455

View
N#Cc1ccccc1C(Cl)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-8
0.451

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O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

LON-WEI-8f408cad-4
0.448

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

AAR-POS-d2a4d1df-23
0.448

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(F)c2)CC1

MAR-TRE-6a44bbf2-18
0.448

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

AAR-POS-d2a4d1df-44
0.446

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAK-UNK-7c9d1431-8
0.441

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1C

MAR-TRE-6a44bbf2-26
0.441

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-68
0.439

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

KAY-MCD-d0fe5261-1
0.439

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)CC1

MAT-POS-ee51dedd-2
0.439

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27
0.439

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=C2)CC1

MAK-UNK-d4768348-1
0.439

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCC=C2)CC1

SAD-SAT-3a925b8b-9
0.439

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

MAR-TRE-6a44bbf2-58
0.439

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-15
0.439

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAR-TRE-6a44bbf2-45
0.438

View
COc1ccc(OC)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

MAK-UNK-7c9d1431-30
0.438

View
O=C(CCl)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccccc3[N+](=O)[O-])CC2)CC1

SAD-SAT-f2e2579e-6
0.438

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1OC

MAK-UNK-7c9d1431-19
0.437

View
O=C(CCl)N1CCC(C(=O)N2CCN(S(=O)(=O)c3ccccc3F)CC2)CC1

SAD-SAT-9a6c5cf3-10
0.436

View
O=C(CCl)N1CCN(S(=O)(=O)c2cpcc(Cl)c2)CC1

SAD-SAT-bc31ec01-4
0.435

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Br)s2)CC1

NIM-UNI-05f93fcc-1
0.433

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

MAK-UNK-7c9d1431-4
0.425

View
CC(C(=O)N1CCN(C(=O)CCl)CC1)c1ccccc1C#N

MAK-UNK-6ca90168-7
0.425

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc([N+](=O)[O-])c2)CC1

TAT-ENA-80bfd3e5-25
0.425

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1

MAK-UNK-7c9d1431-3
0.425

View
O=C(CCl)N1CCN(S(=O)(=O)c2cc(Cl)cc(Cl)c2)CC1

SAD-SAT-bc31ec01-5
0.424

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(C3CC3)cc2)CC1

MAK-UNK-c74072e5-8
0.420

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-17
0.420

View
Cc1ccc(NCc2ccccc2)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

NAU-LAT-f723e322-5
0.420

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC[SH]=N2)CC1

MAK-UNK-d4768348-4
0.418

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

MAR-TRE-6a44bbf2-32
0.414

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(Cl)c2)CC1

MAK-UNK-7c9d1431-10
0.414

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

ABB-MCD-f8003a30-1
0.414

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccccc3)s2)CC1

NIM-UNI-05f93fcc-2
0.413

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCN=C2)CC1

MAK-UNK-d4768348-5
0.412

View
O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAK-UNK-7c9d1431-23
0.412

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CN[SH]=C2)CC1

MAK-UNK-d4768348-2
0.412

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CCS(O)=C2)CC1

MAK-UNK-d4768348-8
0.412

View
O=C(CCl)N1CCN(S(=O)(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-3
0.412

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C(Cl)CC=C2)CC1

SAD-SAT-3a925b8b-6
0.412

View
O=C(CCl)N1CCN(S(=O)(=O)Cc2ccccc2)CC1

MAR-TRE-6a44bbf2-28
0.412

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cccs2)CC1

BEN-DND-76ad4ac9-13
0.411

View
O=C(CCl)N1CCCN(S(=O)(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-12
0.411

View
O=C(CCl)N1CCN(S(=O)(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-2
0.408

View
O=C(CCl)N1CCN(S(=O)(=O)Nc2ccccc2O)CC1

SWA-SYN-d2e6fa14-2
0.408

View
CS1=CC(S(=O)(=O)N2CCN(C(=O)CCl)CC2)=CC1

MAK-UNK-d4768348-7
0.406

View
O=C(CCl)N1CCN(S(=O)(=O)C2=NC[SH]=C2)CC1

MAK-UNK-d4768348-3
0.406

View
O=C(CCl)N1CCN(S(=O)(=O)c2cccc(C(F)(F)F)c2)CC1

IND-SYN-6c8299e8-2
0.405

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cccc(F)c2)CC1

BEN-DND-76ad4ac9-14
0.405

View
CCOc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-22
0.403

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccccc3Cl)s2)CC1

NIM-UNI-05f93fcc-3
0.403

View
O=C(CCl)N1CCN(S(=O)(=O)/C=C/c2ccccc2)CC1

MAK-UNK-7c9d1431-27
0.400

View
N#CCC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-18
0.397

View
O=C(CCl)N1CCN(S(=O)(=O)C2=C3CC3[SH]=C2)CC1

SAD-SAT-3a925b8b-7
0.394

View
CCNc1cccc(C#N)c1CN1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-24
0.392

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cc(F)ccc2F)CC1

BEN-DND-76ad4ac9-10
0.390

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(-c3ccc(O)cc3)s2)CC1

NIM-UNI-05f93fcc-14
0.390

View
C#Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-5
0.389

View
Cc1noc(C)c1S(=O)(=O)N1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-24
0.386

View
N#Cc1ccc(S(=O)(=O)N2CCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-f2e2579e-10
0.383

View
N#Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-987948f6-3
0.382

View
Cc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-11
0.382

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAK-UNK-7c9d1431-7
0.382

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCC3)CC1

MAR-TRE-6a44bbf2-49
0.382

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAK-UNK-7c9d1431-5
0.382

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3c(c2)CCCC3)CC1

MAR-TRE-6a44bbf2-31
0.382

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CO)CC1

0.772

View
CCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.759

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CSCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.733

View
CS(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.721

View
CCS(=O)(=O)CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.721

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2C(=O)CCC2=O)CC1

0.714

View
CN(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.710

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COCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.710

View
CC(C)CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.710

View
CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.702

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCCC2)CC1

0.698

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCN(CC(N)=O)CC2)CC1

0.692

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2C(=O)C3=CC=CC=C3C2=O)CC1

0.682

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CC2=CC=CC=C2F)CC1

0.682

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)C(=O)O)CC1

0.678

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CC2=CC=CC=C2)CC1

0.677

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCCCCC2)CC1

0.677

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSCC(N)=O)CC1

0.677

View
CC(=O)OCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.677

View
CCN(CC)CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.677

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2C3CCC2CC3)CC1

0.677

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSCCO)CC1

0.677

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.673

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CC2=CC=CC=C2Cl)CC1

0.672

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCSSCC2)CC1

0.672

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCS(=O)CC2)CC1

0.672

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCCCCCC2)CC1

0.667

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCN(CC(=O)N3CCCC3)CC2)CC1

0.667

View
N#CC1=CC=CC=C1SCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.667

View
CC(=O)CSCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.667

View
CC(C)(C)CSCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.667

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CC2=CC=C(Cl)C=C2)CC1

0.662

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSC2=CC=CC=C2Cl)CC1

0.662

View
CCC(=O)N1CCCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.662

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CS(=O)(=O)C2=CC=CC=C2)CC1

0.657

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCN(C(=O)CN3CCCC3)CC2)CC1

0.657

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSC2=CC=CC=C2)CC1

0.657

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CC3=CC=CC=C3C2)CC1

0.657

View
CC(=O)N1CCN(CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)CC1

0.657

View
CCCN(CCC)CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.657

View
CCN1CCN(CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)CC1

0.657

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN(C2CC2)C2CC2)CC1

0.657

View
CS(=O)(=O)N1CCN(CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)CC1

0.657

View
N#CCCSCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.657

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSC2=C(Cl)C=CC=C2Cl)CC1

0.652

View
CC(Cl)(Cl)C(=O)OCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.652

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CC2CCCCC2)CC1

0.647

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCOCC2)CC1

0.647

View
CN1CCN(CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)CC1

0.647

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCSCC2)CC1

0.647

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCN(C(=O)CO)CC2)CC1

0.647

View
CCC(CC)SCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.647

View
CCC(CC)(CC)SCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.647

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSC2CCC2)CC1

0.647

View
CCC(=O)OCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.647

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)C(=O)N2CCCC2)CC1

0.645

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)COC2=C(Cl)C=CC=C2Cl)CC1

0.643

View
CC1(C)CN(CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)C1(C)C

0.638

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CC2=CC=CS2)CC1

0.638

View
CC1=CC=C(CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)C=C1

0.638

View
CCC(=O)N1CCN(CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)CC1

0.638

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCC3=CC=CC=C3CC2)CC1

0.638

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCC3(CC2)CC3)CC1

0.638

View
CN(CC(=O)N1CCCC1)CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.638

View
CC1(C)CCCN1CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.638

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSC2CCCC2)CC1

0.638

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)N2CCCC2)CC1

0.635

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSC2=CC=C(Cl)C=C2)CC1

0.634

View
N#CC1=CC=CC=C1OCC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.629

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSC2=NC=CC=N2)CC1

0.629

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2C=CC=C(C#N)C2=O)CC1

0.629

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CCC2CCCC2)CC1

0.629

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)COC2=CC=C(Cl)C=C2)CC1

0.625

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSCC2=C(Cl)C=CC=C2Cl)CC1

0.625

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)COC2=CC=C(Br)C=C2)CC1

0.625

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)COC2=CC=CC=C2Cl)CC1

0.625

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCCC23CCCC3)CC1

0.625

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)C2=CC=CC=C2)CC1

0.625

View
CC(C)CC(=O)N1CCCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1

0.623

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(CC(=O)N2CCCC2)CC1

0.621

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN(C#N)C2=CC=CC=C2)CC1

0.620

View
N#CC1=CC=C(OCC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)C=C1

0.620

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CCCC2=CC=CC=C2)CC1

0.620

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CSCC2=CC=CC=C2)CC1

0.620

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)COC(=O)C2=CC=CC=C2)CC1

0.620

View
CN(CC(=O)N1CCN(S(=O)(=O)C2=CC=CC=C2C#N)CC1)C1=CC=CC=C1

0.620

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)N2CCCCC2)CC1

0.615

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)C2=C(Cl)C=CC=C2Cl)CC1

0.612

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(CC(=O)N2CCCCCC2)CC1

0.603

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(CC(=O)N2CCCCC2)CC1

0.603

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CC2=CC(F)=CC=C2)CC1

0.603

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)COC2=CC=C(F)C=C2)CC1

0.603

View
CC1=CC=C(OCC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)C=C1

0.603

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=CC=C2Cl)CC1

0.600

View
N#CC1=CC=CC=C1N1CCN(CC(=O)N2CCN(S(=O)(=O)C3=CC=CC=C3C#N)CC2)CC1

0.595

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCN(C3=CC=CC=C3Cl)CC2)CC1

0.592

View
CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CCl)CC1

0.581

View
N#CC1=CC=CC=C1S(=O)(=O)N1CCN(C(=O)CN2CCN(C3=CC=CC=C3F)CC2)CC1

0.557

View
N#CC1=CC=C(S(=O)(=O)N2CCN(C(=O)CCl)CC2)C=C1

0.508

View
O=C(CCl)N1CCN(S(=O)(=O)C2=CC=CC=C2)CC1

0.500

View
CC(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

0.200

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CNC(=O)c2ccccc2)CC1

0.200

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)Cc2ccc3ccccc3c2)CC1

0.199

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)Cc2cccc3ccccc23)CC1

0.199

View
CC(=O)N1CCN(S(=O)(=O)c2cc(C)ccc2C)CC1

0.199

View
CC(=O)NCC(=O)N1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1

0.199

View
CC(=O)CCN1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.199

View
CC(=O)N1CCN(S(=O)(=O)c2ccc(C)cc2)CC1

0.198

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.195

View
CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

0.194

View
CCC(=O)N1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1

0.194

View
N#Cc1ccccc1S(=O)(=O)N1CCNCC1

0.194

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCNC(=O)C2CC2)CC1

0.194

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)C2CCCCC2)CC1

0.192

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)C(C)Cl)CC2)cc1

0.192

View
COC(=O)N(C)CC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.191

View
CC(C)CNC(=O)CN1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.191

View
CC(C(=O)N(C(C)C)C(C)C)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.191

View
CNC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.191

View
CC(=O)N1CCN(S(=O)(=O)c2cccc(Cl)c2C)CC1

0.190

View
CCN(CCN1CCCC1)S(=O)(=O)c1ccccc1C#N

0.189

View
CC(Cl)C(=O)N1CCN(S(=O)(=O)c2ccccc2)CC1

0.188

View
COCCN1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.188

View
CC(=O)N1CCN(S(=O)(=O)c2cc(F)ccc2C)CC1

0.187

View
Cl.N#Cc1ccccc1S(=O)(=O)N1CCNCC1

0.187

View
CC1CC(C)CN(CC(=O)N2CCN(S(=O)(=O)c3ccccc3C#N)CC2)C1

0.187

View
N#CCCN1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.184

View
CC(=O)N1CCN(S(=O)(=O)c2cc(Cl)ccc2C)CC1

0.184

View
N#Cc1ccccc1S(=O)(=O)N1CCN(CCCO)CC1

0.183

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCc2ccccc2)CC1

0.181

View
COCCCC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.174

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)C2CCCC2)CC1

0.173

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)c2ccccc2)CC1

0.173

View
CC(C)NC(=O)CN1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.172

View
C=CCN1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.168

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CCC2CCCC2)CC1

0.168

View
CC(=O)N1CCN(S(=O)(=O)c2ccc(C#N)cc2)CC1

0.166

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)C2CCC2)CC1

0.165

View
CC(=O)N1CCN(S(=O)(=O)c2c(C)cc(C)cc2C)CC1

0.165

View
CC(C)(C)SCC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.164

View
C#CCN1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.163

View
Cl.N#Cc1ccccc1S(=O)(=O)N1CCN(CCO)CC1

0.161

View
[C]C([C])=[C]C(=O)N1[C][C]N(S(=O)(=O)c2ccccc2C#N)[C][C]1

0.155

View
C[N+]1(C)CCN(S(=O)(=O)c2ccccc2C#N)CC1.[I-]

0.148

View
Cc1ccc(C)c(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c1

0.146

View
CCC(C)(C)C(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.145

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

0.142

View
CCN1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.142

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

0.142

View
CN1CCN(S(=O)(=O)c2ccccc2C#N)CC1.Cl

0.142

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CN2CCCCC2)CC1

0.140

View
C=CCCC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.140

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)C2CC2)CC1

0.140

View
CC(C)(C)CC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.135

View
N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)CN2CCN(CC(=O)NC3CC3)CC2)CC1

0.135

View
COCC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.130

View
CCCCC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.120

View
CC(C)(C)C(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.120

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)c(C)c1

0.110

View
CCC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.087

View
CC(=O)N1CCN(S(=O)(=O)c2ccccc2C#N)CC1

0.052

View
N1(S(=O)(=O)C2=C(C#N)C=CC=C2)CCN(C(C)=O)CC1

0.963

View
N1(S(=O)(=O)C2=C(C#N)C=CC=C2)CCN(C=O)CC1

0.922

View
N1(S(=O)(=O)C2=C(C#N)C=CC=C2)CCN(CC)CC1

0.908

View
N1(S(=O)(=O)C2=C(C#N)C=CC=C2)CCN(CC#N)CC1

0.897

View
N1(S(=O)(=O)C2=C(C#N)C=CC=C2)CCN(C)CC1

0.890

View

Discussion: