Molecule Details

CC(=O)N1CCN(C(=O)CCl)CC1
piperazine-chloroacetamide Enamine Mcule MolPort
View on Fragalysis x1493
Molecular Properties
SMILES:
CC(=O)N1CCN(C(=O)CCl)CC1
MW: 204.657
Fraction sp3: 0.75
HBA: 2
HBD: 0
Rotatable Bonds: 1
TPSA: 40.62
cLogP: -0.0841000000000001
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-04558
Enamine SCR: Z56886547
Enamine REAL: Z56886547
Enamine Extended REAL: m_270062____7594792____8147258
Mcule: MCULE-8064927847
MolPort: MolPort-002-498-218
O=C(CCl)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-9
0.760

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CC(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-987948f6-5
0.636

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C=C(C)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-987948f6-4
0.600

View
NC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-704ed37c-11
0.594

View
CNC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-704ed37c-12
0.571

View
C=CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-16
0.543

View
N#CCC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-18
0.528

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N#CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-17
0.528

View
CC(C)N(C)C(=O)N1CCN(C(=O)CCl)CC1

YOI-UNK-15f562e8-4
0.526

View
CC(C)N(C)C(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-bf9c9ac8-1
0.526

View
CCNC(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-bf9c9ac8-2
0.526

View
O=C(CCl)N1CCC1

MAK-UNK-95198336-3
0.517

View
O=C(CCl)N1CCCC1

MAK-UNK-4b073b5c-16
0.516

View
O=C(CCl)N1CCN(C(=O)N2CCCC2)CC1

MAK-UNK-704ed37c-10
0.514

View
O=C(CCl)N1CCN(C(=O)C2CC2)CC1

SAD-SAT-5b1897b2-9
0.514

View
NS(=O)(=O)CC(=O)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-8
0.514

View
CC(C)NC(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-9a3d118a-1
0.513

View
O=C(CCl)N1CCN(C(=O)N2CCCCCC2)CC1

MAK-UNK-704ed37c-13
0.487

View
CC1CCN(C(=O)CCl)CC1

SAD-SAT-d8079f6f-4
0.486

View
O=C(CCl)N1CCCCCC1

SAD-SAT-d8079f6f-5
0.485

View
O=C(CCl)N1CCCCC1

SAD-SAT-d8079f6f-3
0.485

View
O=C(CCl)N1CCCCCCC1

SAD-SAT-d8079f6f-6
0.471

View
O=C(CCl)N1CCN(C(=O)n2cccc2)CC1

MAK-UNK-52a1ef4b-1
0.463

View
C#CCN1CCN(C(=O)CCl)CC1

TOB-UNK-c2aba166-1
0.462

View
O=C(CCl)N1CCS(=O)(=O)CC1

SAD-SAT-bc31ec01-2
0.457

View
O=C(CCl)N1CCOCC1

MAK-UNK-f983951f-21
0.457

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Cc1ccccc1CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-10
0.457

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AHN-SAT-de2502ba-8
0.444

View
O=C(CCl)N1CCN(C(=O)N2C=COC2)CC1

MAK-UNK-52a1ef4b-3
0.444

View
O=C(CCl)N1CCN(C(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-4
0.444

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-25
0.444

View
O=C(CCl)N1C[S+]([O-])C1

MAK-UNK-95198336-11
0.441

View
O=C(CCl)N1CCC(N2CCN(C(=O)CCl)CC2)CC1

WAR-XCH-b0339bbe-18
0.439

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O=C(CCl)N1CCN(C(=O)c2ccccc2)CC1

MAK-UNK-987948f6-2
0.432

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CC(C)(C)NC(=O)CN1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-56
0.422

View
O=C(CCl)N1CCN(C2CCS(=O)(=O)C2)CC1

SAD-SAT-5b1897b2-6
0.422

View
CS1=NC(CC(=O)N2CCN(C(=O)CCl)CC2)C=C1

SAD-SAT-1b030f84-4
0.417

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1C

ASH-SAT-43770c7d-10
0.417

View
O=C(CCl)N1CCC2(CC1)OCCO2

SAD-SAT-65574d3f-5
0.415

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O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

MAR-TRE-6a44bbf2-61
0.413

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CNC(=O)NS(=O)(=O)N1CCN(C(=O)CCl)CC1

SWA-SYN-6423ea73-5
0.413

View
CNC(=O)NS(=O)(=O)N1CCN(C(=O)CCl)CC1

SWA-SYN-d2e6fa14-5
0.413

View
O=C(CCl)N1CCN(C(=O)N2C=CSC2)CC1

MAK-UNK-52a1ef4b-2
0.413

View
O=C(CCl)N1CCN(C(=O)c2ccsc2)CC1

MAK-UNK-6ca90168-20
0.413

View
O=C(CCl)N1CCN(C(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-5
0.413

View
O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

AAR-POS-d2a4d1df-29
0.413

View
N#CC1CCN(C(=O)CCl)CC1

MAK-UNK-6c8f5f75-1
0.410

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NC(=O)C1CCN(C(=O)CCl)CC1

MAK-UNK-750cfbcc-1
0.410

View
O=C(CCl)N1CCN(C(=O)c2cc(O)cc(Cl)c2)CC1

SAD-SAT-581007d4-5
0.408

View
O=C(CCl)N1CSC1

MAK-UNK-95198336-6
0.406

View
O=C(CCl)N1COC1

MAK-UNK-95198336-7
0.406

View
O=C(CCl)N1CNC1

MAK-UNK-95198336-4
0.406

View
CNC(=O)C1CCN(C(=O)CCl)CC1

MAK-UNK-750cfbcc-2
0.405

View
O=C(CCl)N1CCN(C(=O)c2cscc2Cl)CC1

SAD-SAT-1b030f84-5
0.404

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O=C(CCl)N1CCN(C(=O)c2cccs2)CC1

AAR-POS-0daf6b7e-16
0.404

View
O=C(CCl)N1CCN(C(=O)C2=CC[SH]=C2)CC1

SAD-SAT-3a925b8b-1
0.404

View
O=C(CCl)N1CCN(C(=O)c2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-25
0.404

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O=C(CCl)N1CCN(c2ncccn2)CC1

VIK-SYN-9a3d118a-4
0.400

View
Cc1ccccc1CN1CCN(C(=O)CCl)CC1

MAK-UNK-7c9d1431-20
0.400

View
CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-13
0.400

View
CC(=O)c1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-78
0.400

View
O=C(CCl)N1CCN(c2ncccn2)CC1

VIK-SYN-bf9c9ac8-7
0.400

View
O=C(CCl)N1CCN(c2ncccn2)CC1

MAR-TRE-6a44bbf2-87
0.400

View
Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-4
0.400

View
O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.400

View
CC(C#N)C(C(=O)N1CCN(C(=O)CCl)CC1)S(N)(=O)=O

SAD-SAT-89668ff1-8
0.400

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2)CC1

AHN-SAT-de2502ba-7
0.396

View
O=C(CCl)N1CCN(c2cccc(Cl)c2)CC1

SAD-SAT-65574d3f-9
0.396

View
COc1ccc(N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-0daf6b7e-18
0.396

View
N#Cc1ccccc1CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-9
0.392

View
O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.391

View
N#Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-987948f6-3
0.388

View
O=C(CCl)N1CCN(C(=O)c2cccc(Cl)c2)CC1

MAK-UNK-6ca90168-15
0.388

View
Cc1cccc(N2CCN(C(=O)CCl)CC2)c1

SAD-SAT-5b1897b2-4
0.388

View
CN(CN1CCC(O)CC1)CN1CCN(C(=O)CCl)CC1

MAK-UNK-e4a48a85-14
0.388

View
O=C(CCl)N1CCN(C(c2ccccc2)c2ccccc2)CC1

SIM-SYN-f15aaa3a-1
0.383

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.383

View
O=C(CCl)N1CCCSCC1

SAD-SAT-edc8a235-3
0.381

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccsc2)CC1

MAT-POS-ee51dedd-2
0.380

View
Cc1ccc(CN2CCN(C(=O)CCl)CC2)o1

MAR-LAB-ca4662a6-2
0.380

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27
0.380

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-68
0.380

View
CN(C)c1cc(F)c(N2CCN(C(=O)CCl)CC2)c(F)c1

NIM-UNI-310206f0-6
0.380

View
CC(CCc1ccccc1)N1CCN(C(=O)CCl)CC1

MAK-UNK-af83ef51-2
0.377

View
O=C(CCl)N1CCN(c2ccccc2F)CC1

SAD-SAT-5b1897b2-10
0.375

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

SAD-SAT-581007d4-7
0.373

View
Cc1cc(Cl)cc(CN2CCN(C(=O)CCl)CC2)c1

SAD-SAT-581007d4-2
0.373

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-d2e6fa14-1
0.373

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-1
0.373

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1

MAK-UNK-7c9d1431-12
0.373

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.373

View
O=C(CCl)N1CCN(Cc2cc(O)cc(Cl)c2)CC1

MAT-POS-2db6411e-2
0.373

View
O=C(CCl)N1CCOC1

SAD-SAT-6b5a89f0-2
0.368

View
O=C(CCl)N1CCSC1

MAK-UNK-4b073b5c-17
0.368

View
CC(=O)N1CCN(C(=O)Cc2ccccn2)CC1

JON-UIO-066ce08b-3
0.367

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAR-TRE-6a44bbf2-21
0.367

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

LON-WEI-8f408cad-7
0.367

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAK-UNK-7c9d1431-9
0.367

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

AAR-POS-0daf6b7e-13
0.367

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

MAK-UNK-212f693e-8
0.367

View
CC(=O)N1CCN(C(=O)CCl)CC1

1.000

View
CC(=O)N1CCCN(C(=O)CCl)CC1

0.697

View
CCC(=O)N1CCN(C(=O)CCl)CC1

0.645

View
CCN(CC)C(=O)N1CCN(C(=O)CCl)CC1

0.583

View
CC(=O)N1CCN(C(=O)CO)CC1

0.581

View
CN(C)CC(=O)N1CCN(C(=O)CCl)CC1

0.571

View
CC(C)(C)C(=O)N1CCN(C(=O)CCl)CC1

0.571

View
COCC(=O)N1CCN(C(=O)CCl)CC1

0.571

View
CC(C)C(=O)N1CCN(C(=O)CCl)CC1

0.571

View
CC(C)CC(=O)N1CCN(C(=O)CCl)CC1

0.571

View
COC(=O)N1CCN(C(=O)CCl)CC1

0.571

View
CN(C)C(=O)N1CCN(C(=O)CCl)CC1

0.571

View
CC(=O)N1CCN(C(=O)CN)CC1

0.562

View
CC(C)N1CCN(C(=O)CCl)CC1

0.559

View
CCCN1CCN(C(=O)CCl)CC1

0.556

View
CC(=O)CCC(=O)N1CCN(C(C)=O)CC1

0.545

View
CC(C)(C)N1CCN(C(=O)CCl)CC1

0.543

View
CCOC(=O)N1CCN(C(=O)CCl)CC1

0.541

View
CC(=O)N1CCN(C(=O)CCNC(=O)CCl)CC1

0.538

View
CC(=O)N1CCN(C(=O)CCCC(=O)N2CCN(C(C)=O)CC2)CC1

0.529

View
CC(=O)N1CCN(C(=O)CSCC(=O)N2CCN(C(C)=O)CC2)CC1

0.529

View
CSCC(=O)N1CCN(C(C)=O)CC1

0.529

View
CC(=O)N1CCN(C(=O)CCO)CC1

0.529

View
CCNC(=O)N1CCN(C(=O)CCl)CC1

0.526

View
CCN(CC)CC(=O)N1CCN(C(=O)CCl)CC1

0.526

View
CCC(CC)C(=O)N1CCN(C(=O)CCl)CC1

0.526

View
CC(C)(C)OC(=O)N1CCN(C(=O)CCl)CC1

0.526

View
CC(=O)N1CCN(C(=O)CN(C)C)CC1

0.514

View
CC(=O)N1CCN(C(=O)COCC(=O)N2CCN(C(C)=O)CC2)CC1

0.514

View
CC(=O)N1CCN(C(=O)CN2CCN(CC(=O)N3CCN(C(C)=O)CC3)CC2)CC1

0.514

View
CC(=O)N1CCN(C(=O)CC(C)(C)C)CC1

0.514

View
COCC(=O)N1CCN(C(C)=O)CC1

0.514

View
CC(=O)N1CCN(C(=O)CC(C)C)CC1

0.514

View
CC(=O)N1CCN(C(=O)CCN)CC1

0.514

View
CNCC(=O)N1CCN(C(C)=O)CC1

0.514

View
CCC(=O)N1CCCN(C(=O)CCl)CC1

0.514

View
O=C(CCl)N1CCN(C(=O)N2CCCC2)CC1

0.514

View
O=C(CCl)N1CCN(C(=O)C(=O)N2CCCC2)CC1

0.514

View
C=C(Cl)CCC(=O)N1CCN(C(C)=O)CC1

0.514

View
CCS(=O)(=O)N1CCN(C(=O)CCl)CC1

0.514

View
CC(C)(C)NC(=O)N1CCN(C(=O)CCl)CC1

0.513

View
CC(=O)N1CCN(C(=O)CCCCCC(=O)N2CCN(C(C)=O)CC2)CC1

0.500

View
CC(=O)N1CCN(C(=O)CCCCCCC(=O)N2CCN(C(C)=O)CC2)CC1

0.500

View
CC(=O)C1CCN(C(=O)CCl)CC1

0.500

View
CC(=O)N1CCN(C(=O)CC(C)CC(=O)N2CCN(C(C)=O)CC2)CC1

0.500

View
CC(=O)N1CCN(C(=O)COC(C)(C)C)CC1

0.500

View
CC(C)CN1CCN(C(=O)CCl)CC1

0.500

View
CC(=O)N1CCN(C(=O)CC(F)(F)F)CC1

0.500

View
CC(=O)N1CCN(C(=O)CS(C)(=O)=O)CC1

0.500

View
CC(=O)N1CCN(C(=O)CC2CC2)CC1

0.500

View
C=C(C)CCC(=O)N1CCN(C(C)=O)CC1

0.500

View
CC(=O)N1CCN(C(=O)CON)CC1

0.500

View
NC(=O)N1CCCN(C(=O)CCl)CC1

0.500

View
CCC(C)N1CCN(C(=O)CCl)CC1

0.500

View
O=C(CCl)N1CCN(C(=O)N2CCCCC2)CC1

0.487

View
O=C(CCl)N1CCN(CCN2CCCC2)CC1

0.487

View
O=C(CCl)N1CCN(C(=O)CN2CCCC2)CC1

0.487

View
CC(=O)NCCC(=O)N1CCN(C(C)=O)CC1

0.487

View
CC(=O)N1CCN(C(=O)CCCCCCCC(=O)N2CCN(C(C)=O)CC2)CC1

0.486

View
CC(=O)N1CCN(C(=O)CCCCCCCCC(=O)N2CCN(C(C)=O)CC2)CC1

0.486

View
CC(=O)N1CCN(CC(=O)N2CCN(C(C)=O)CC2)CC1

0.486

View
CC(=O)CCCC(=O)N1CCN(C(C)=O)CC1

0.486

View
CC(=O)N1CCN(C(=O)CCC(N)=O)CC1

0.486

View
CCCCC(=O)N1CCN(C(C)=O)CC1

0.486

View
CC(=O)NCC(=O)N1CCN(C(C)=O)CC1

0.486

View
CC(=O)OCC(=O)N1CCN(C(C)=O)CC1

0.486

View
CC(=O)N1CCN(C(=O)C[C@H](C)N)CC1

0.486

View
CC(=O)N1CCN(C(=O)CC(C)N)CC1

0.486

View
CC(=O)N1CCN(C(=O)C[C@@H](C)N)CC1

0.486

View
O=C(CCl)N1CCN(C2CC2)CC1

0.486

View
COC(=O)CC(=O)N1CCN(C(C)=O)CC1

0.486

View
CC(=O)N1CCN(C(=O)CC2(CC(=O)N3CCN(C(C)=O)CC3)CCCC2)CC1

0.475

View
CCC(CC)CC(=O)N1CCN(C(C)=O)CC1

0.474

View
CC(=O)N1CCN(C(=O)COCCOCC(=O)N2CCN(C(C)=O)CC2)CC1

0.474

View
CC(=O)N1CCN(C(=O)CCSCCC(=O)N2CCN(C(C)=O)CC2)CC1

0.474

View
CC(=O)N1CCN(C(=O)CCOCCC(=O)N2CCN(C(C)=O)CC2)CC1

0.474

View
CC(=O)N1CCN(C(=O)CCC(C)C)CC1

0.474

View
CC(=O)CSCC(=O)N1CCN(C(C)=O)CC1

0.474

View
CCOCC(=O)N1CCN(C(C)=O)CC1

0.474

View
O=C(CCl)N1CCCCCCCC1

0.471

View
CC(C)OCCN1CCN(C(=O)CCl)CC1

0.465

View
CC(=O)NCC(=O)N1CCCN(C(=O)CCl)CC1

0.465

View
CC(C)CC(=O)N1CCCN(C(=O)CCl)CC1

0.463

View
CC(=O)N1CCN(C(=O)CC2=CC=C(CC(=O)N3CCN(C(C)=O)CC3)C=C2)CC1

0.462

View
CC(=O)N1CCN(C(=O)CN2CCCC2)CC1

0.462

View
CC(=O)N1CCN(CC(=O)N2CCN(C(=O)CN3CCN(C(C)=O)CC3)CC2)CC1

0.459

View
O=C(CCl)N1CCS(=O)(=O)CC1

0.457

View
CC(C)C(=O)N1CCCN(C(=O)CCl)CC1

0.452

View
COC(=O)N1CCCN(C(=O)CCl)CC1

0.452

View
CCN1CCCN(C(=O)CCl)CC1

0.450

View
CC(=O)N1CCN(C(=O)CCC(=O)N2CCOCC2)CC1

0.450

View
CN(C)C1CCN(C(=O)CCl)CC1

0.447

View
CC(C)(C)C1CCN(C(=O)CCl)CC1

0.447

View
CC(=O)N1CCCN(C(=O)CO)CC1

0.447

View
CCCC(CCC)CC(=O)N1CCN(C(C)=O)CC1

0.439

View
CC(=O)N1CCCN(C(=O)CN)CC1

0.436

View
CC(=O)N1CCN(C(=O)CCl)[C@H](C)C1

0.429

View
CC(=O)N1CCN(CCN2CCN(C(C)=O)CC2)CC1

0.424

View
CC(C)(C)N1CCCN(C(=O)CCl)CC1

0.419

View
CC(=O)N1CCN(C(=O)CC2=C(Cl)C=CC=C2Cl)CC1

0.413

View
CC(=O)N1CCN(CC1)C(=O)CCl

1.000

View
ClCC(=O)N1CCN(CC1)C(=O)CCl

0.760

View
CN1CCN(CC1)C(=O)CCl

0.594

View
Cl.CN1CCN(CC1)C(=O)CCl

0.576

View
CC(C)N1CCN(CC1)C(=O)CCl

0.559

View
Cl.CCN1CCN(CC1)C(=O)CCl

0.543

View
Cl.CCCN1CCN(CC1)C(=O)CCl

0.541

View
ClCC(=O)N1CCN(CC1)C=O

0.514

View
ClCC(=O)N1CCNCC1

0.471

View
Cl.ClCC(=O)N1CCNCC1

0.457

View
Cl.CN(C)C(=O)CN1CCN(CC1)C(=O)CCl

0.452

View
Cl.ClCC(=O)N1CCN(CC#C)CC1

0.450

View
Cl.CC(=O)N1CCN(CCCl)CC1

0.444

View
ClCC(=O)N1CCNC(=O)C1

0.318

View
CN1CCN(CC1)C(=O)C(Cl)(Cl)Cl

0.244

View
CC(=O)NCCNC(=O)CCl

0.231

View
CN(CCN(C)C(=O)CCl)C(=O)CCl

0.216

View
ClCC(=O)NCCNC(=O)CCl

0.206

View
Cl.CN(C)CCNC(=O)CCl

0.195

View
ClC(Cl)C(=O)NCCN(CCNC(=O)C(Cl)Cl)CCNC(=O)C(Cl)Cl

0.186

View
Cl.ClC(Cl)C(=O)NCCN(CCNC(=O)C(Cl)Cl)CCNC(=O)C(Cl)Cl

0.182

View
C(N1CCN(C(C)=O)CC1)(=O)C

0.871

View
C(N1CCN(C(C)=O)CC1)(C(Cl)Cl)=O

0.868

View
C(N1CCN(C=O)CC1)(C(Cl)Cl)=O

0.817

View
C(N1CCN(C=O)CC1)(=O)C

0.807

View
C(N1CCN(C(C)=O)CC1)(=O)CC

0.788

View

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