Molecule Details

O=C(CCl)N1CCC1
Enamine Mcule MolPort
Molecular Properties
SMILES:
O=C(CCl)N1CCC1
MW: 133.03
Fraction sp3: 0.8
HBA: 1
HBD: 0
Rotatable Bonds: 1
TPSA: 20.31
cLogP: 0.46
Covalent Warhead: ✔️
Covalent Fragment: ✔️
Source
Enamine BB: EN300-11195
Enamine SCR: Z57039583
Mcule: MCULE-1485330958
MolPort: MolPort-002-022-776
O=C(CCl)N1CCN(S(=O)(=O)c2cccs2)CC1

LON-WEI-8f408cad-3

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O=C(CCl)N1CCCC1

MAK-UNK-4b073b5c-16
0.783

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O=C(CCl)N1CCCCC1

SAD-SAT-d8079f6f-3
0.720

View
O=C(CCl)N1CCCCCC1

SAD-SAT-d8079f6f-5
0.720

View
O=C(CCl)N1CCCCCCC1

SAD-SAT-d8079f6f-6
0.692

View
O=C(CCl)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-9
0.652

View
CC(=O)N1CCN(C(=O)CCl)CC1

AAR-POS-0daf6b7e-21
0.517

View
O=C(CCl)N1CCN(C(=O)N2CCCC2)CC1

MAK-UNK-704ed37c-10
0.515

View
O=C(CCl)N1CCS(=O)(=O)CC1

SAD-SAT-bc31ec01-2
0.500

View
O=C(CCl)N1CCOCC1

MAK-UNK-f983951f-21
0.500

View
O=C(CCl)N1CNC1

MAK-UNK-95198336-4
0.500

View
O=C(CCl)N1CSC1

MAK-UNK-95198336-6
0.500

View
O=C(CCl)N1COC1

MAK-UNK-95198336-7
0.500

View
NC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-704ed37c-11
0.500

View
O=C(CCl)N1CCCSCC1

SAD-SAT-edc8a235-3
0.486

View
O=C(CCl)N1CCN(C(=O)N2CCCCCC2)CC1

MAK-UNK-704ed37c-13
0.486

View
CC1CCN(C(=O)CCl)CC1

SAD-SAT-d8079f6f-4
0.484

View
O=C(CCl)N1CCC(C(=O)N2CCCC2)CC1

MAK-UNK-750cfbcc-3
0.459

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O=C(CCl)N1CCC(C(=O)N2CCCC2)CC1

MAR-TRE-6a44bbf2-79
0.459

View
CC(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-987948f6-5
0.455

View
C=CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-16
0.455

View
N#CC1CCN(C(=O)CCl)CC1

MAK-UNK-6c8f5f75-1
0.441

View
NC(=O)C1CCN(C(=O)CCl)CC1

MAK-UNK-750cfbcc-1
0.441

View
CNC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-704ed37c-12
0.441

View
N#CC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-17
0.441

View
N#CCC(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-18
0.441

View
O=C(CCl)N1CCOC1

SAD-SAT-6b5a89f0-2
0.438

View
O=C(CCl)N1CCSC1

MAK-UNK-4b073b5c-17
0.438

View
O=C(CCl)N1CCC(C(=O)N2CCCCC2)CC1

AAR-POS-0daf6b7e-9
0.436

View
O=C(CCl)N1CCC(C(=O)N2CCCCC2)CC1

VIR-GIT-7b3d3065-2
0.436

View
O=C(CCl)N1CCC(C(=O)N2CCCCCC2)CC1

MAK-UNK-750cfbcc-5
0.436

View
O=C(CCl)N1C[S+]([O-])C1

MAK-UNK-95198336-11
0.433

View
CC(C)NC(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-9a3d118a-1
0.432

View
O=C(CCl)N1CCN(C(=O)C2CC2)CC1

SAD-SAT-5b1897b2-9
0.429

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O=C(CCl)N1CCO1

MAK-UNK-95198336-5
0.429

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C=C(C)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-987948f6-4
0.429

View
NS(=O)(=O)CC(=O)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-8
0.429

View
O=C(CCl)NCC(=O)N1CCCC1

SAD-SAT-65574d3f-7
0.417

View
C#CCN1CCN(C(=O)CCl)CC1

TOB-UNK-c2aba166-1
0.417

View
NC(=O)C1CCCN(C(=O)CCl)C1

SAD-SAT-65574d3f-6
0.410

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CC(C)N(C)C(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-bf9c9ac8-1
0.405

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CCNC(=O)N1CCN(C(=O)CCl)CC1

VIK-SYN-bf9c9ac8-2
0.405

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O=C(CCl)N1CCC2(CC1)OCCO2

SAD-SAT-65574d3f-5
0.405

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CC(C)N(C)C(=O)N1CCN(C(=O)CCl)CC1

YOI-UNK-15f562e8-4
0.405

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N#CC1CCCN(C(=O)CCl)C1

MAK-UNK-6c8f5f75-2
0.400

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CNC(=O)C1CCN(C(=O)CCl)CC1

MAK-UNK-750cfbcc-2
0.395

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O=C(CCl)N1CCC(N2CCN(C(=O)CCl)CC2)CC1

WAR-XCH-b0339bbe-18
0.395

View
O=C(CCl)N1CCCO1

MAK-UNK-4b073b5c-19
0.394

View
O=C(CCl)N1CCN(C(=O)n2cccc2)CC1

MAK-UNK-52a1ef4b-1
0.385

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N#CC1CN(C(=O)CCl)C1

MAK-UNK-95198336-9
0.382

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O=C(CCl)N1CCCN(C(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-8
0.375

View
O=C1CN(C(=O)CCl)CN1

SAD-SAT-edc8a235-10
0.371

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CC1CCCN(C(=O)C2CCN(C(=O)CCl)CC2)C1

MAK-UNK-750cfbcc-4
0.370

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C[C@H]1CCCN(C(=O)C2CCN(C(=O)CCl)CC2)C1

MAR-TRE-6a44bbf2-66
0.370

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O=C(CCl)N1CCN(CN2CCCOCC2)CC1

JOH-UNI-27ac80fd-4
0.370

View
NC(=O)C1CCN(C(=O)CCl)CN1

MAK-UNK-704ed37c-14
0.368

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NC(=O)C1CCN(C(=O)CCl)CO1

MAK-UNK-704ed37c-16
0.368

View
N#CC1CCN(C(=O)CCl)C1

SAD-SAT-edc8a235-7
0.368

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Cc1ccc(CN2CCCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-21
0.367

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O=C(CCl)N1CNO1

MAK-UNK-95198336-8
0.367

View
C=CC(=O)N1CCC1

SAD-SAT-6b5a89f0-9
0.357

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O=C(CCl)N1CCN(c2ncccn2)CC1

VIK-SYN-9a3d118a-4
0.357

View
O=C(CCl)N1CCN(c2ncccn2)CC1

VIK-SYN-bf9c9ac8-7
0.357

View
O=C(CCl)N1CCN(c2ncccn2)CC1

MAR-TRE-6a44bbf2-87
0.357

View
O=C(CCl)N1CCN(C(=O)c2ccccc2)CC1

MAK-UNK-987948f6-2
0.357

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O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.357

View
O=C(CCl)N1CCC(C(=O)N2CCCO2)CC1

MAK-UNK-704ed37c-2
0.356

View
O=C(CCl)N1C=CCC1

MAK-UNK-4b073b5c-15
0.353

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NC(=O)C1CCN(C(=O)CCl)CS1

MAK-UNK-704ed37c-17
0.350

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CC(C)N(C)C(=O)C1CCN(C(=O)CCl)CC1

VIR-GIT-7b3d3065-3
0.349

View
CC(C)N(C)C(=O)C1CCN(C(=O)CCl)CC1

AAR-POS-0daf6b7e-19
0.349

View
CC(C)(C)NC(=O)CN1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-56
0.349

View
O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.349

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O=C(CCl)N1CCN(C2CCS(=O)(=O)C2)CC1

SAD-SAT-5b1897b2-6
0.349

View
CS1=NC(CC(=O)N2CCN(C(=O)CCl)CC2)C=C1

SAD-SAT-1b030f84-4
0.348

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Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

TAT-ENA-80bfd3e5-20
0.346

View
Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-41
0.346

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CC1CCCCN1C(=O)CCl

MAK-UNK-f983951f-27
0.342

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CNC(=O)NS(=O)(=O)N1CCN(C(=O)CCl)CC1

SWA-SYN-d2e6fa14-5
0.341

View
O=C(CCl)N1CCN(C(=O)N2C=COC2)CC1

MAK-UNK-52a1ef4b-3
0.341

View
O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

MAR-TRE-6a44bbf2-61
0.341

View
O=C(CCl)N1CCN(C(=O)c2ccsc2)CC1

MAK-UNK-6ca90168-20
0.341

View
O=C(CCl)N1CCN(C(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-4
0.341

View
O=C(CCl)N1CCN(C(=O)c2ccoc2)CC1

SAD-SAT-3a925b8b-5
0.341

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Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AHN-SAT-de2502ba-8
0.341

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.341

View
O=C(CCl)N1CCN(C(c2ccccc2)c2ccccc2)CC1

SIM-SYN-f15aaa3a-1
0.341

View
O=C(CCl)N1CCN(C(=O)c2ccco2)CC1

AAR-POS-d2a4d1df-29
0.341

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-25
0.341

View
O=C(CCl)N1CCC(C(=O)N2CCNC2)CC1

MAK-UNK-704ed37c-1
0.341

View
O=C(CCl)N1CCN(C(=O)N2C=CSC2)CC1

MAK-UNK-52a1ef4b-2
0.341

View
CNC(=O)NS(=O)(=O)N1CCN(C(=O)CCl)CC1

SWA-SYN-6423ea73-5
0.341

View
O=C(CCl)N1CCCN(S(=O)(=O)c2cccs2)CC1

BEN-DND-76ad4ac9-13
0.340

View
O=C(CCl)N1CCCN(S(=O)(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-12
0.340

View
O=C(CCl)N1CCCN(S(=O)(=O)Cc2ccccc2)CC1

BEN-DND-76ad4ac9-9
0.340

View
O=C(CCl)N1CCN(C(=O)c2cscc2Cl)CC1

SAD-SAT-1b030f84-5
0.333

View
O=C(CCl)N1CCC(C(=O)N2CCSC2)CC1

MAK-UNK-704ed37c-4
0.333

View
O=C(CCl)N1CCCN(S(=O)(=O)c2ccccc2F)CC1

BEN-DND-76ad4ac9-11
0.333

View
O=C(CCl)N1CCN(C(=O)C2=CC[SH]=C2)CC1

SAD-SAT-3a925b8b-1
0.333

View
O=C(CCl)N1CCN(S(=O)(=O)c2cocn2)CC1

SAD-SAT-3a925b8b-3
0.333

View
O=C(CCl)N1CCN(C(=O)c2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-25
0.333

View
O=C(CCl)N1CCCCCCCC1

0.850

View
CC(=O)N1CCCN(C(=O)CCl)CC1

0.750

View
CCC(=O)N1CCCN(C(=O)CCl)CC1

0.750

View
NC(=O)N1CCCN(C(=O)CCl)CC1

0.750

View
O=C(CCl)N1CCN(C(=O)N2CCCC2)CC1

0.739

View
O=C(CCl)N1CCN(C(=O)C(=O)N2CCCC2)CC1

0.739

View
O=C(CCl)N1CCN(C(=O)N2CCCCC2)CC1

0.708

View
O=CN1CCCN(C(=O)CCl)CC1

0.667

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CCN1CCCN(C(=O)CCl)CC1

0.667

View
O=C(CCl)N1CCCN(CC(=O)N2CCCC2)CC1

0.667

View
CC(C)C(=O)N1CCCN(C(=O)CCl)CC1

0.667

View
CC(C)(C)N1CCCN(C(=O)CCl)CC1

0.667

View
COC(=O)N1CCCN(C(=O)CCl)CC1

0.667

View
CC(C)CC(=O)N1CCCN(C(=O)CCl)CC1

0.667

View
O=C(CCl)N1CCN(CC(=O)N2CCCC2)CC1

0.654

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CC(C)N1CCCN(C(=O)CCl)CC1

0.643

View
O=C(CCl)N1CCCN(C2CC2)CC1

0.643

View
O=C(CCl)N1CCCN(C(=O)CC2CCCC2)CC1

0.643

View
O=C(CCl)N1CCN(CC(=O)N2CCCCCC2)CC1

0.630

View
O=C(CCl)N1CCN(CC(=O)N2CCCCC2)CC1

0.630

View
O=C(CCl)N1CCCS(=O)(=O)CC1

0.630

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O=C(CCl)N1CCCC2(CC1)CC2

0.630

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CC(=O)N1CCN(C(=O)CCl)CC1

0.625

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CCC(=O)N1CCN(C(=O)CCl)CC1

0.625

View
CS(=O)(=O)N1CCCN(C(=O)CCl)CC1

0.621

View
O=C(CCl)N1CCCN(CC(F)(F)F)CC1

0.621

View
NC(=O)CN1CCCN(C(=O)CCl)CC1

0.621

View
CCOC(=O)N1CCCN(C(=O)CCl)CC1

0.621

View
O=C(CCl)N1CCCN(C2CCCC2)CC1

0.621

View
O=C(CCl)N1CCCN(CC(F)F)CC1

0.621

View
CC(=O)NCC(=O)N1CCCN(C(=O)CCl)CC1

0.621

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NS(=O)(=O)N1CCCN(C(=O)CCl)CC1

0.621

View
O=C(CCl)N1CCN(CCN2CCCC2)CC1

0.615

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O=C(CCl)N1CCN(C(=O)CN2CCCC2)CC1

0.615

View
O=C(CCl)N1CCC(C2CCCC2)CC1

0.615

View
O=C(CCl)N1CCC(CC(=O)N2CCCC2)CC1

0.607

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O=C(CCl)N1CCCC(O)CC1

0.607

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O=C(CCl)N1CCCC(F)(F)CC1

0.607

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CC1(C)CCCN(C(=O)CCl)CC1

0.607

View
O=C(CCl)N1CCCN(C(=O)c2ccccc2)CC1

0.600

View
O=C(CCl)N1CCCN(c2ccccc2)CC1

0.600

View
O=C(CCl)N1CCS(=O)(=O)CC1

0.600

View
CC(C)(C)OC(=O)N1CCCN(C(=O)CCl)CC1

0.600

View
C=CCN1CCCN(C(=O)CCl)CC1

0.600

View
O=C(CCl)N1CCC(N2CCCC2)CC1

0.593

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CCC1CCCN(C(=O)CCl)CC1

0.586

View
O=C(CCl)N1CCCC(N2CCCC2)CC1

0.586

View
O=C(CCl)N1CCCN(C(=O)c2ccc(Cl)cc2)CC1

0.581

View
CN(C)CC(=O)N1CCN(C(=O)CCl)CC1

0.577

View
O=C(CCl)N1CCC(N2CCCCC2)CC1

0.571

View
O=C(CCl)N1CCN(C2CCCC2)CC1

0.571

View
O=C(CCl)N1CCC(OC2CCCC2)CC1

0.571

View
O=C(CCl)N1CCN(C2CCC2)CC1

0.571

View
O=C(CCl)N1CCCC2(CCCC2)C1

0.571

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O=C(CCl)N1CCCN2CCCC2C1

0.567

View
O=C(CCl)N1CCCC(CO)CC1

0.567

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CCC1(CC)CCCN(C(=O)CCl)CC1

0.567

View
O=C(CCCCC(=O)N1CCC1)N1CCC1

0.565

View
O=C(CCCC(=O)N1CCC1)N1CCC1

0.565

View
O=C(CCl)N1CCCN(CC2CCCCC2)CC1

0.562

View
O=C(CCl)N1CCCN(c2ccc(F)cc2)CC1

0.562

View
O=C(CCl)N1CCCN(C(=O)CCc2ccccc2)CC1

0.562

View
CC(C)COC(=O)N1CCCN(C(=O)CCl)CC1

0.562

View
O=C(CCl)N1CCCN(C(=O)Oc2ccccc2)CC1

0.562

View
O=C(CCl)N1CCCN(C(=O)c2ccc(F)cc2)CC1

0.562

View
CC(C)N1CCN(C(=O)CCl)CC1

0.556

View
O=C(CCl)N1CCN(C2CC2)CC1

0.556

View
CC(C)(C)C(=O)N1CCN(C(=O)CCl)CC1

0.556

View
COCC(=O)N1CCN(C(=O)CCl)CC1

0.556

View
CC(C)C(=O)N1CCN(C(=O)CCl)CC1

0.556

View
CC(C)CC(=O)N1CCN(C(=O)CCl)CC1

0.556

View
COC(=O)N1CCN(C(=O)CCl)CC1

0.556

View
CC(C)(C)N1CCN(C(=O)CCl)CC1

0.556

View
CN(C)C(=O)N1CCN(C(=O)CCl)CC1

0.556

View
O=C(CCl)N1CCN(C2CCCCC2)CC1

0.552

View
O=C(CCl)N1CCC(OC2CCCCC2)CC1

0.552

View
O=C(CCl)N1CCN(C(=O)CC2CCCCC2)CC1

0.552

View
O=C(CCl)N1CCCC2(CCCCC2)C1

0.552

View
O=C(CCl)N1CCCC2(CCCCCC2)C1

0.552

View
O=C(CCl)N1CCCCC2(CCCCC2)C1

0.552

View
CC(C)(C)C1CCCN(C(=O)CCl)CC1

0.548

View
CC(C)C1CCCN(C(=O)CCl)CC1

0.548

View
CN(C)C1CCCN(C(=O)CCl)CC1

0.548

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CC(C(=O)N1CCCC1)N1CCN(C(=O)CCl)CC1

0.548

View
O=C(CCl)N1CCCN(Cc2ccccc2)CC1

0.545

View
O=C(CCl)N1CCCN(C2CCOCC2)CC1

0.545

View
O=C(CCCCCCC(=O)N1CCC1)N1CCC1

0.542

View
O=C(CSCC(=O)N1CCC1)N1CCC1

0.542

View
O=C(COCC(=O)N1CCC1)N1CCC1

0.542

View
O=C(CCCCCCCCC(=O)N1CCC1)N1CCC1

0.542

View
O=C(CCCCCC(=O)N1CCC1)N1CCC1

0.542

View
O=C(CCCCCCCC(=O)N1CCC1)N1CCC1

0.542

View
O=C(CN1CCN(CC(=O)N2CCC2)CC1)N1CCC1

0.542

View
CCC(=O)N1CCCN(C(=O)CC)CC1

0.542

View
NC(=O)C1CCN(C(=O)CCl)CC1

0.536

View
O=C(CCl)N1CCN(CCO)CC1

0.536

View
O=C(CCl)N1CCN(C(=O)C(=O)N2CCOCC2)CC1

0.536

View
O=C(CCl)N1CCN(CC(F)(F)F)CC1

0.536

View
O=C(CCl)N1CCN(C(=O)N2CCOCC2)CC1

0.536

View
O=C(CCl)N1CCC(CO)CC1

0.536

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CCN(C(=O)CCl)C1CC1

0.182

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CN(C(=O)CCl)C1CC1

0.182

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CC(C)CN(C)C(=O)CCl

0.182

View
CN(CC(C)(C)C)C(=O)CCl

0.182

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CC(Cl)C(=O)N1CCC1

0.174

View
CCCNC(=O)CCl

0.158

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CCCN(CCC)C(=O)CCl

0.077

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C(N1CCC1)(C(Cl)Cl)=O

0.781

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C(N1CCC1)(=O)C

0.770

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C(N(CCC)C)(C(Cl)Cl)=O

0.706

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Discussion: