Molecular Properties | |
SMILES: | O=C(Cc1cccc(Cl)c1)Nc1[nH]nc2cc(F)ccc12 |
MW: | 303.06 |
Fraction sp3: | 0.07 |
HBA: | 2 |
HBD: | 2 |
Rotatable Bonds: | 3 |
TPSA: | 57.78 |
cLogP: | 3.54 |
Covalent Warhead: | ✗ |
Covalent Fragment: | ✗ |
Activity Data | |
IC50 (µM) - Fluorescence: | 99.5 |
IC50 (µM) - RapidFire: | 91.4887190568217 |
Order Status | |
Ordered: | 2020-09-29 |
Synthesis Location: | enamine |
Shipped: | 2020-10-28 |
JAG-UCB-52b62a6f-1
EDJ-MED-c8e7a002-3
0.658
EDJ-MED-c8e7a002-2
0.566
EDJ-MED-c8e7a002-13
0.519
EDJ-MED-c8e7a002-9
0.494
EDJ-MED-c8e7a002-14
0.481
JIN-POS-6dc588a4-11
0.469
EDJ-MED-c8e7a002-11
0.456
NAU-LAT-a5c7d7cb-10
0.456
JAN-GHE-5a013bed-11
0.452
EDJ-MED-c8e7a002-5
0.442
PET-UNK-158bee2a-3
0.440
JAG-UCB-52b62a6f-9
0.429
MIC-UNK-d935700b-1
0.425
JAN-GHE-5a013bed-9
0.425
PET-UNK-158bee2a-2
0.425
JAN-GHE-5a013bed-6
0.425
EDG-MED-0da5ad92-21
0.421
JAN-GHE-5a013bed-7
0.419
NAU-LAT-e1818702-10
0.419
JOH-UNI-6fede743-5
0.419
PET-UNK-158bee2a-1
0.418
VLA-UNK-4cf5aa07-1
0.418
EDG-MED-0da5ad92-12
0.416
RUB-POS-1325a9ea-17
0.415
MIC-UNK-66895286-1
0.413
PET-UNK-158bee2a-4
0.413
EDJ-MED-c8e7a002-16
0.405
EDJ-MED-c5ca5386-1
0.405
JAN-GHE-5a013bed-4
0.403
VLA-UNK-411a133b-1
0.403
EDG-MED-0da5ad92-13
0.403
VLA-UCB-00f2c2b3-7
0.402
EDJ-MED-c8e7a002-15
0.400
EDJ-MED-6e43a462-8
0.400
EDG-MED-0da5ad92-14
0.397
VLA-UNK-4cf5aa07-2
0.395
EDG-MED-0da5ad92-2
0.395
JAN-GHE-5a013bed-8
0.395
RUB-POS-1325a9ea-13
0.393
JIN-POS-6dc588a4-13
0.393
JIN-POS-6dc588a4-22
0.393
TRY-UNI-714a760b-6
0.392
JAN-GHE-5a013bed-10
0.390
VLA-UNK-411a133b-2
0.390
MIC-UNK-d935700b-2
0.388
RUB-POS-1325a9ea-18
0.388
PET-UNK-b1ef24dc-4
0.388
ALP-POS-902f21bb-1
0.388
JIN-POS-6dc588a4-12
0.388
MAT-POS-199e2e7c-2
0.388
ABI-SAT-4d06482b-2
0.388
JIN-POS-6dc588a4-19
0.386
MAT-POS-bb423b95-6
0.386
ALP-POS-3b848b35-3
0.386
ADA-UCB-6c2cb422-1
0.386
JOH-UNI-6fede743-3
0.386
JIN-POS-6dc588a4-8
0.386
PET-UNK-8df914d1-4
0.385
JAG-UCB-a3ef7265-15
0.385
SAM-UNK-2684b532-13
0.385
EDJ-MED-49816e9b-2
0.385
ALP-POS-95b75b4d-8
0.385
JAG-UCB-a3ef7265-17
0.385
EDG-MED-0da5ad92-16
0.385
NAU-LAT-e1818702-7
0.385
MIC-UNK-7574fcc6-1
0.384
AGN-NEW-c7b24fe3-4
0.383
AGN-NEW-c7b24fe3-5
0.383
TRY-UNI-714a760b-3
0.383
RUB-POS-1325a9ea-22
0.383
JIN-POS-6dc588a4-7
0.381
EDJ-MED-c8e7a002-12
0.381
EDJ-MED-49816e9b-3
0.380
ALP-POS-95b75b4d-6
0.380
EDJ-MED-49816e9b-5
0.380
RUB-POS-1325a9ea-4
0.379
MAT-POS-29385cc1-3
0.379
MAT-POS-c20a539d-6
0.379
AGN-NEW-c7b24fe3-1
0.378
MAT-POS-90fd5f68-41
0.378
PET-UNK-f92d7c0c-4
0.377
PET-UNK-f92d7c0c-5
0.377
MAT-POS-3cc264b0-1
0.376
EDJ-MED-50fe53e8-1
0.376
EDJ-MED-50fe53e8-2
0.376
MAT-POS-f7918075-6
0.376
RUB-POS-1325a9ea-12
0.376
PET-UNK-8df914d1-3
0.375
EDJ-MED-c8e7a002-6
0.375
EDG-MED-0da5ad92-15
0.375
MAT-POS-29385cc1-4
0.375
SAM-UNK-2684b532-12
0.373
JIN-POS-6dc588a4-5
0.373
JIN-POS-6dc588a4-4
0.373
SAM-UNK-2684b532-11
0.373
JIN-POS-6dc588a4-21
0.372
MAT-POS-bb423b95-8
0.372
RUB-POS-1325a9ea-2
0.372
JIN-POS-6dc588a4-16
0.372
JOH-UNI-6fede743-1
0.372