Submission Details

Molecule(s):
COc1ccc2c(NC(=O)Cc3cccc(Cl)c3)noc2c1

EDJ-MED-c8e7a002-1

COc1ccc2c(NC(=O)Cc3cccc(Cl)c3)noc2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
COc1ccc2n[nH]c(NC(=O)Cc3cccc(Cl)c3)c2c1

EDJ-MED-c8e7a002-2

COc1ccc2n[nH]c(NC(=O)Cc3cccc(Cl)c3)c2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
COc1ccc2c(NC(=O)Cc3cccc(Cl)c3)[nH]nc2c1

EDJ-MED-c8e7a002-3

COc1ccc2c(NC(=O)Cc3cccc(Cl)c3)[nH]nc2c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccn2cnnc2c1NC(=O)Cc1cccc(Cl)c1

EDJ-MED-c8e7a002-4

Cc1ccn2cnnc2c1NC(=O)Cc1cccc(Cl)c1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1cc(C(F)(F)F)nc2n[nH]c(NC(=O)Cc3cccc(Cl)c3)c12

EDJ-MED-c8e7a002-5

Cc1cc(C(F)(F)F)nc2n[nH]c(NC(=O)Cc3cccc(Cl)c3)c12

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1nn(C)c2[nH]nc(NC(=O)Cc3cccc(Cl)c3)c12

EDJ-MED-c8e7a002-6

Cc1nn(C)c2[nH]nc(NC(=O)Cc3cccc(Cl)c3)c12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1c(Cl)ncn2cnnc12

EDJ-MED-c8e7a002-7

O=C(Cc1cccc(Cl)c1)Nc1c(Cl)ncn2cnnc12

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1c(Cl)ncn2nnnc12

EDJ-MED-c8e7a002-8

O=C(Cc1cccc(Cl)c1)Nc1c(Cl)ncn2nnnc12

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1n[nH]c2ccc(F)cc12

EDJ-MED-c8e7a002-9

O=C(Cc1cccc(Cl)c1)Nc1n[nH]c2ccc(F)cc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1[nH]nc2cc(F)ccc12

EDJ-MED-c8e7a002-10

O=C(Cc1cccc(Cl)c1)Nc1[nH]nc2cc(F)ccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1n[nH]c2ccccc12

EDJ-MED-c8e7a002-11

O=C(Cc1cccc(Cl)c1)Nc1n[nH]c2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1cccc2cn[nH]c12

EDJ-MED-c8e7a002-12

O=C(Cc1cccc(Cl)c1)Nc1cccc2cn[nH]c12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1[nH]nc2cccc(F)c12

EDJ-MED-c8e7a002-13

O=C(Cc1cccc(Cl)c1)Nc1[nH]nc2cccc(F)c12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1[nH]nc2cccnc12

EDJ-MED-c8e7a002-14

O=C(Cc1cccc(Cl)c1)Nc1[nH]nc2cccnc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1n[nH]c2ccnc(Br)c12

EDJ-MED-c8e7a002-15

O=C(Cc1cccc(Cl)c1)Nc1n[nH]c2ccnc(Br)c12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1n[nH]c2ccncc12

EDJ-MED-c8e7a002-16

O=C(Cc1cccc(Cl)c1)Nc1n[nH]c2ccncc12

3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Cc1cccc(Cl)c1)Nc1c(Cl)ncn2c(O)nnc12

EDJ-MED-c8e7a002-17

O=C(Cc1cccc(Cl)c1)Nc1c(Cl)ncn2c(O)nnc12

3-aminopyridine-like Ordered Check Availability on Manifold View

Design Rationale:

Batch of meta chloro amides with bicycloaromatic isoquinoline replacements suggested by Jag Heer in design JAG-UCB-52b62a6f.

Inspired By:
Discussion: