Molecule Details

C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1
3-aminopyridine-like Enamine Assayed
View on Fragalysis x2705
Molecular Properties
SMILES:
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1
MW: 445.567
Fraction sp3: 0.31
HBA: 4
HBD: 2
Rotatable Bonds: 7
TPSA: 90.98
cLogP: 4.87202
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine SCR: Z4439011584
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 4.0468147
Average Inhibition @ 50 µM - Fluorescence: 4.7055155
Relative Solubility @ 20 µM: 0.92
Relative Solubility @ 100 µM: 0.78
Order Status
Shipped: 2020-04-09
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-48
0.854

View
C=CC(=O)N(c1cc(C(C)(C)C#N)n[nH]1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

DAR-DIA-2b784ede-42
0.837

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(CC)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-52
0.772

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1C(C)C)c1cccnc1

DAR-DIA-2b784ede-51
0.755

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(CC)cccc1CCO)c1cccnc1

DAR-DIA-2b784ede-50
0.755

View
C=CC(=O)N(c1cc(C(C)(C)Cl)n[nH]1)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-45
0.740

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(CO)cccc1C(C)C)c1cccnc1

DAR-DIA-2b784ede-49
0.670

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-d1c9908a-10
0.646

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CO)c1ccc(N)nc1

DAR-DIA-2b784ede-43
0.644

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-21
0.639

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-46
0.636

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CO)c1cnccc1C

DAR-DIA-2b784ede-47
0.618

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)[C@H](C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-1
0.600

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-2
0.600

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-39
0.600

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-2
0.590

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-42
0.588

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-29
0.584

View
C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-18
0.584

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-d1c9908a-8
0.573

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-45
0.573

View
C=CC(=O)N(c1ccc2ncsc2c1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-48
0.560

View
CCC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-3
0.539

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1C)c1cccnc1

NIM-NMI-8bb27a2b-6
0.505

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-35
0.473

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1Cl)c1cccnc1

NIM-NMI-8bb27a2b-7
0.473

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1C)c1cccnc1

NIM-NMI-8bb27a2b-22
0.471

View
C=CC(=O)N(c1cc2c(s1)CCCC2)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-46
0.466

View
C=CC(=O)N(c1cc(C(C)(C)C)nn1CC)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-12
0.462

View
C=CC(=O)N(c1cc(C(C)(C)Cl)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-34
0.447

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1Cl)c1cccnc1

NIM-NMI-8bb27a2b-21
0.445

View
C=CC(=O)N(c1ccc(CCl)nc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-7
0.436

View
C=CC(=O)N(c1cc(C(C)(C)C#N)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-36
0.436

View
C=CC(=O)N(c1ccc(CCl)cn1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-8
0.434

View
C=CC(=O)N(c1ccc(CCl)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-9
0.432

View
C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)Nc1c(CC)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-53
0.432

View
C=CC(=O)N(c1ccc(CC#N)nc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-11
0.429

View
C=CC(=O)N(C1CC2(CCCC2)CN1)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-44
0.429

View
C=CC(=O)N(c1cc(C(C)(C)C)nn1Cc1ccccc1)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-14
0.425

View
C=CC(=O)N(c1cc(C(C)(C)C)nn1C)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-11
0.423

View
C=CC(=O)N(c1ccc(CC#N)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-10
0.421

View
C=CC(=O)N(c1ccc(CC)c(I)c1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-73
0.419

View
C=CC(=O)N(c1ccc(CC#N)cn1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-12
0.419

View
C=CC(=O)N(c1cc(C(C)(C)C)nn1C(C)C)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-13
0.415

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-b8d98729-15
0.414

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCC)c1cccnc1

LON-WEI-adc59df6-30
0.408

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1)c1cccnc1

LON-WEI-adc59df6-41
0.404

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-d1c9908a-3
0.404

View
C=CC(=O)N(c1ccc(C2(Cl)CCCC2)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-16
0.400

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCC(C)C)c1cccnc1

NIM-NMI-8bb27a2b-4
0.400

View
C=CC(=O)N(c1ccc(C2(Cl)CCCC2)nc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-18
0.400

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(OC)c1)c1cccnc1

LON-WEI-adc59df6-12
0.398

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CC1)c1cccnc1

NIM-NMI-8bb27a2b-3
0.398

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCCC)c1cccnc1

NIM-NMI-8bb27a2b-2
0.396

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-23
0.396

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC)c1cccnc1

LON-WEI-adc59df6-3
0.396

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1c(C)cccc1CO)c1cnccc1C

DAR-DIA-2b784ede-38
0.395

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1C)c1cccnc1

LON-WEI-adc59df6-16
0.395

View
C=CC(=O)N(c1ccc(C2(Cl)CCCC2)cn1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-17
0.393

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-43
0.393

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1)c1cccnc1

LON-WEI-adc59df6-46
0.393

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)CC)c1cccnc1

LON-WEI-adc59df6-31
0.393

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1CC)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-16
0.391

View
C=CC(=O)N(c1cnc(N(C)C)nc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-70
0.390

View
C=CC(=O)N(c1ccc(C2(C#N)CCCC2)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-15
0.390

View
C=CC(=O)N(c1ccc(C2(C#N)CCCC2)nc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-14
0.390

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCC(=O)OCC)c1cccnc1

NIM-NMI-8bb27a2b-12
0.389

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Br)c1)c1cccnc1

LON-WEI-adc59df6-5
0.389

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1C)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-15
0.389

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-8f408cad-8
0.388

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(=O)OC)c1)c1cccnc1

LON-WEI-adc59df6-24
0.388

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCC(=O)OC)c1cccnc1

NIM-NMI-8bb27a2b-11
0.387

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCN(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-9
0.387

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CCC1)c1cccnc1

ERI-UCB-fbdd3ea1-7
0.387

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CC1)c1cccnc1

LON-WEI-adc59df6-44
0.387

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-b8d98729-16
0.387

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Cl)c1C)c1cccnc1

LON-WEI-adc59df6-9
0.386

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1

LON-WEI-adc59df6-15
0.386

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-8f408cad-9
0.385

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1Cl)c1cccnc1

LON-WEI-adc59df6-42
0.385

View
C#Cc1cncc(N(C(=O)C=C)C(C(=O)NC(C)(C)C)c2cccnc2)c1

LON-WEI-adc59df6-74
0.385

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1OC)c1cccnc1

LON-WEI-adc59df6-45
0.385

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)C)c1cccnc1

LON-WEI-adc59df6-21
0.385

View
C=CC(=O)N(c1ccc(C2(C#N)CCCC2)cn1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-13
0.384

View
C=CC(=O)N(c1cccc(Cl)c1)C(C(=O)NC(C)(C)C)c1cccnc1

JAN-GHE-d851b096-8
0.383

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-d1c9908a-9
0.383

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCCC(=O)OCC)c1cccnc1

LON-WEI-adc59df6-7
0.383

View
C#Cc1cccc(N(C(=O)C=C)C(C(=O)NC(C)(C)C)c2cccnc2)c1

LON-WEI-adc59df6-103
0.382

View
C=CC(=O)N(c1ccc(C(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-80
0.381

View
C=CC(=O)N(c1cnc(C)s1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-81
0.381

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1OC)c1cccnc1

LON-WEI-adc59df6-18
0.381

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CCCC1)c1cccnc1

ERI-UCB-fbdd3ea1-6
0.381

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCN(C)C)c1cccnc1

LON-WEI-adc59df6-29
0.380

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCC1)c1cccnc1

LON-WEI-adc59df6-14
0.380

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-b8d98729-36
0.378

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCC(=O)OCC)c1cccnc1

LON-WEI-adc59df6-2
0.377

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccc(Br)cc1)c1cccnc1

LON-WEI-b8d98729-35
0.377

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCc1ccc(F)cc1)c1cccnc1

LON-WEI-adc59df6-23
0.377

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCC(=O)OC(C)(C)C)c1cccnc1

NIM-NMI-8bb27a2b-5
0.377

View
C=CC(=O)N(c1cc(C)cc(N)c1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-101
0.376

View
CCC1=CC=CC(C)=C1NC(=O)C(O)C1=CC=CN=C1

0.467

View
CCC1=CC=CC(C)=C1NC(=O)C1=CC(C(C)(C)C)=N[NH]1

0.436

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC1=CC(C(C)(C)C)=N[NH]1

0.433

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C)C1=CC=CN=C1

0.429

View
CCC1=CC=CC(C)=C1NC(=O)CN(C)C(C)C1=CC=CN=C1

0.426

View
CCC1=CC=CC(C)=C1NC(=O)N(C)C(C)C1=CC=CN=C1

0.424

View
CCC1=CC=CC(C)=C1NC(=O)C1=CC=CN=C1

0.424

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C1=CC=CN=C1)C(C)(C)CO

0.423

View
CCC1=CC=CC(C)=C1NC(=O)NC(C1=CC=CN=C1)C(C)(C)CO

0.422

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C(O)C1=CC=CN=C1

0.422

View
CCC1=CC=CC(C)=C1NC(=O)N1CCN(C(C)C2=CC=CN=C2)CC1

0.419

View
CCC1=CC=CC(C)=C1NC(=O)NC(C)C1=CC=CN=C1

0.418

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C(C1=CC=CN=C1)C(C)C

0.417

View
CCC1=CC=CC(C)=C1NC(=O)NC(C1=CC=CC=C1)C1=CC=CN=C1

0.416

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)N(C)C(C)C1=CC=CN=C1

0.416

View
CCC1=CC=CC(C)=C1NC(=O)CSC(C)C1=CC=CN=C1

0.416

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC(C)C1=CC=CN=C1

0.414

View
CCC1=CC=CC(C)=C1NC(=O)CN(C)CC(O)C1=CC=CN=C1

0.413

View
CCC1=CC=CC(C)=C1NC(=O)CC1=CC=CN=C1

0.413

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)N1CCN(C(C)C2=CC=CN=C2)CC1

0.411

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC(C1=CC=CC=C1)C1=CC=CN=C1

0.408

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C1=CC(C(C)(C)C)=N[NH]1

0.408

View
CCC1=CC=CC(C)=C1NC(=O)CN1CCN(C(C)C2=CC=CN=C2)CC1

0.407

View
CCC1=CC=CC(C)=C1NC(=O)NCC(C1=CC=CN=C1)C(C)C

0.402

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NCC(C1=CC=CN=C1)C(C)C

0.398

View
CCC1=CC=CC(C)=C1NC(=S)NNC(=O)C1=CC(C(C)(C)C)=N[NH]1

0.398

View
CCC1=CC=CC(C)=C1NC(=O)C(C)OC1=CC=CN=C1

0.394

View
CCC1=CC=CC(C)=C1NC(=O)NNC(=O)C1=CC=CN=C1

0.390

View
CCC1=CC=CC(C)=C1NC(=O)N(C)CC1=CC=CN=C1

0.390

View
CCC1=CC=CC(C)=C1NC(=S)NNC(=O)C(C)(C)C1=CC=CN=C1

0.381

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C(C)(C)C1=CC=CN=C1

0.381

View
CCC1=CC=CC(C)=C1NNC(=O)C(O)C1=CC=CN=C1

0.380

View
CCC1=CC=CC(C)=C1NC(=O)C=CC1=CC=CN=C1

0.380

View
C=CCC(C(=O)NC1=C(C)C=CC=C1CC)N(C)C

0.379

View
CCC1=CC=CC(C)=C1NC(=O)CN1C=CN=C1C(O)C1=CC=CN=C1

0.378

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C1=CC=CN=C1)C1CCCCC1

0.378

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NCC(C)(C)C1=CC=CN=C1

0.375

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C1=CC=NC=C1

0.375

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)N(CC)CC1=CC=CN=C1

0.375

View
CCC1=CC=CC(C)=C1NC(=O)C1=CC(C(F)(F)F)=N[NH]1

0.374

View
CCC1=CC=CC(C)=C1NC(=O)CCC1=CC=CN=C1

0.374

View
CCC1=CC=CC(C)=C1NC(=O)C(Br)C(C)(C)C

0.374

View
C=CC(O)C(=O)NC1=C(C)C=CC=C1CC

0.374

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C(C)(F)F

0.374

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC(C1=CC=CN=C1)C1CCCCC1

0.373

View
CCC1=CC=CC(C)=C1NNC(=O)C(C1=CC=CN=C1)C(C)C

0.373

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C)CC1=CC=CN=C1

0.371

View
CCC1=CC=CC(C)=C1NC(=O)CSC1=N[NH]C(C2=CC=CN=C2)=N1

0.369

View
CCC1=CC=CC(C)=C1NC(=O)NCC(C)(C)C1=CC=CN=C1

0.369

View
CCC1=CC=CC(C)=C1NC(=O)NCC(=O)NC1=CC=CN=C1

0.369

View
CCC1=CC=CC(C)=C1NNC(=O)C1=CC(C(C)(C)C)=N[NH]1

0.366

View
C=CCC(CC=C)C(=O)NC1=C(C)C=CC=C1CC

0.366

View
CCC1=CC=CC(C)=C1NNC(=O)NC(C)C1=CC=CN=C1

0.365

View
CCC1=CC=CC(C)=C1NC(=O)NC(C)CC1=CC=CN=C1

0.365

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)N(C)CC1=CC=CN=C1

0.365

View
CCC1=CC=CC(C)=C1NNC(=O)NCC(C1=CC=CN=C1)C(C)C

0.364

View
CCC1=CC=CC(C)=C1NC(=O)C1=CC=CC(NC(=O)C2=CC=CN=C2)=C1

0.364

View
CC(C)(C)C1=N[NH]C(NC(=O)C(O)C2=CC=CN=C2)=C1

0.364

View
CCC1=CC=CC(C)=C1NC(=O)N(CC)CC1=CC=CN=C1

0.363

View
CCC1=CC=CC(C)=C1NC(=O)CN(CC)CC1=CC=CN=C1

0.362

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C1=CN=CC=N1

0.360

View
CCC1=CC=CC(C)=C1NC(=O)NCCC1=CC=CN=C1

0.359

View
CCC1=CC=CC(C)=C1NC(=O)C(F)C1=CC=CC=C1

0.358

View
CCC1=CC=CC(C)=C1NC(=O)NCC1=CC=CN=C1

0.356

View
CC(C)C(C(=O)NC1=CC(C(C)(C)C)=N[NH]1)C1=CC=CN=C1

0.353

View
CCC1=CC=CC(C)=C1NC(=O)NCC1=CN=CC=C1C(C)(C)C

0.352

View
CCC1=CC=CC(C)=C1NC(=O)CC1=CSC(C2=CC=CN=C2)=N1

0.352

View
CCC1=CC=CC(C)=C1NC(=O)CNC1=CC(C2=CC=CN=C2)=CC=C1C

0.351

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)N(CC1=CC=CN=C1)CC1=CC=CC=C1C

0.351

View
C=CC(C)(C)NC(=O)NC1=C(C)C=CC=C1CC

0.351

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C1=C(C)[NH]N=C1C

0.350

View
CCC1=CC=CC(C)=C1NC(=O)CN1C=CN=C1C(C)(C)C

0.350

View
CCC1=CC=CC(C)=C1NC(=O)CSC1=NC=CC(C(C)(C)C)=N1

0.349

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC1=CC(C2=CC=CN=C2)=CC=C1C

0.349

View
CCC1=CC=CC(C)=C1NC(=O)C(F)F

0.348

View
C=CCN1C(SCC(=O)NC2=C(C)C=CC=C2CC)=NN=C1C1=CC=CN=C1

0.347

View
CCC1=CC=CC(C)=C1NC(=O)NC1=CC(C)=N[NH]1

0.347

View
CCC1=CC=CC(C)=C1NNC(=O)C(C)(C)C1=CC=CN=C1

0.347

View
CCC1=CC=CC(C)=C1NC(=O)CN1N=CC=C1C1=CC=CN=C1

0.345

View
CCC1=CC=CC(CC)=C1NC(=O)C(=O)NC1=CC(C(C)(C)C)=N[NH]1

0.343

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)NC(C)C1=CC=CN=C1

0.340

View
CCC1=CC=CC(C)=C1NC(=O)C(F)(F)C1=CN=CC=N1

0.340

View
CCC1=CC=CC(C)=C1NC(=O)N(CC1=CC=NC=C1)CC1=CC=CN=C1

0.339

View
CCC1=CC=CC(C)=C1NC(=O)C1=CN=C(C2=CC=CN=C2)S1

0.339

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)N(CC1=CC=NC=C1)CC1=CC=CN=C1

0.339

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C1=CC=CC(Cl)=C1

0.337

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)N(C)CC(O)C1=CC=CN=C1

0.337

View
CCC1=CC=CC(C)=C1NC(=O)NCCOC1=CC=CN=C1

0.336

View
CCC1=CC=CC(C)=C1NNC(=O)NCC(C)(C)C1=CC=CN=C1

0.336

View
CCC1=CC=CC(C)=C1NC(=O)C1=CSC(C2=CC=CN=C2)=N1

0.336

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)NC(C1=CC=CC=C1)C1=CC=CN=C1

0.330

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)OC(=O)C1=CC(C(C)(C)C)=N[NH]1

0.330

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)OC(=O)C(C1=CC=CN=C1)C(C)C

0.324

View
CCC1=CC=CC(CC)=C1NC(=O)NC(C1=CC=CN=C1)C(C)(C)CO

0.324

View
CCC1=CC=CC(C)=C1NC(=O)C(C)OCC1=CC=NC=C1

0.324

View
CCC1=CC=CC(CC)=C1NC(=O)NC(C)C1=CC=CN=C1

0.320

View
CCC1=CC=CC(C)=C1NNC(=O)C(=O)NC1=CC(C2=CC=CN=C2)=CC=C1C

0.310

View
CCC1=CC=CC(CC)=C1NC(=O)NCC(C1=CC=CN=C1)C(C)C

0.308

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)OC(=O)C(C)(C)C1=CC=CN=C1

0.302

View
CCC1=CC=CC(CC)=C1NC(=O)C(=O)NC1=CC(C2=CC=CN=C2)=CC=C1C

0.279

View


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