Molecule Details

C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1
3-aminopyridine-like Enamine Assayed
View on Fragalysis x2694
Molecular Properties
SMILES:
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1
MW: 448.523
Fraction sp3: 0.28
HBA: 6
HBD: 1
Rotatable Bonds: 7
TPSA: 97.56
cLogP: 4.58312
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine SCR: Z4439011520
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 12.87613
Average Inhibition @ 50 µM - Fluorescence: 23.43133
Average Inhibition @ 20 µM - RapidFire: 14.308904645
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 0.91
Order Status
Shipped: 2020-04-09
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1C)c1cccnc1

NIM-NMI-8bb27a2b-6
0.674

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-d1c9908a-3
0.674

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-23
0.652

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CC1)c1cccnc1

NIM-NMI-8bb27a2b-3
0.648

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1ccc(OC(F)(F)F)cc1)c1cccnc1

NIM-NMI-8bb27a2b-8
0.646

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCC(=O)OC)c1cccnc1

NIM-NMI-8bb27a2b-11
0.645

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CCC1)c1cccnc1

ERI-UCB-fbdd3ea1-7
0.628

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-46
0.626

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-37
0.626

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1Cl)c1cccnc1

NIM-NMI-8bb27a2b-7
0.626

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-40
0.616

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CCCC1)c1cccnc1

ERI-UCB-fbdd3ea1-6
0.615

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1ccc2ccccc2c1)c1cccnc1

NIM-NMI-8bb27a2b-9
0.614

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-b8d98729-15
0.614

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCC(C)C)c1cccnc1

NIM-NMI-8bb27a2b-4
0.611

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCN(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-9
0.611

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-8
0.610

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-28
0.610

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCC(=O)OCC)c1cccnc1

NIM-NMI-8bb27a2b-12
0.608

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCC(=O)OC(C)(C)C)c1cccnc1

NIM-NMI-8bb27a2b-5
0.608

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCCC)c1cccnc1

NIM-NMI-8bb27a2b-2
0.604

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-30
0.604

View
C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-26
0.604

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CCCCC1)c1cccnc1

NIM-NMI-8bb27a2b-1
0.602

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CCCCC1)c1cccnc1

ERI-UCB-fbdd3ea1-5
0.602

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-d1c9908a-4
0.598

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1ccnc(NC(C)(C)C)c1)c1cccnc1

ERI-UCB-fbdd3ea1-28
0.587

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC1CCN(C)CC1)c1cccnc1

ERI-UCB-fbdd3ea1-8
0.584

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCc1ccccc1)c1cccnc1

NIM-NMI-8bb27a2b-10
0.580

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCc1ccc(Cl)cc1)c1cccnc1

NIM-NMI-8bb27a2b-13
0.569

View
C=CC(=O)N(c1ccc2ncsc2c1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-1
0.560

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCc1cccc(F)c1)c1cccnc1

LON-WEI-babf2c61-10
0.558

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCN1CCN(C)CC1)c1cccnc1

ERI-UCB-fbdd3ea1-10
0.552

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCc1cccc(Cl)c1)c1cccnc1

NIM-NMI-8bb27a2b-14
0.547

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1C)c1cccnc1

LON-WEI-adc59df6-16
0.519

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1OC)c1cccnc1

LON-WEI-adc59df6-45
0.519

View
C=CC(=O)N(c1cc(C(F)(F)F)on1)C(C(=O)NC1CCCCC1)c1cccnc1

JAN-GHE-d851b096-7
0.505

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC(C)(C)C)c1ccncc1

ERI-UCB-fbdd3ea1-26
0.495

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC(C)(C)C)c1ccccc1

ERI-UCB-fbdd3ea1-24
0.495

View
C=CC(=O)N(c1ccccn1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

BRU-LEF-e1854a6f-1
0.490

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)[C@@H](C(=O)NC)c1cnccc1C

DAR-DIA-2b784ede-31
0.480

View
CC(=O)C(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-33
0.480

View
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)/C=C/c1ccccc1)c1cc(C(C)(C)C)on1

ERI-UCB-fbdd3ea1-32
0.477

View
C=CC(=O)N(c1cc(C2CC2)on1)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-30
0.471

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(OC)c1)c1cccnc1

LON-WEI-adc59df6-12
0.467

View
C=CC(=O)N(c1cc(CC2CC2)on1)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-31
0.462

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-d1c9908a-7
0.457

View
C=CC(=O)N(C(C(=O)Nc1ccc(OC)cc1)c1cccnc1)C(C)(C)C

RAL-MED-9a5eb9cb-14
0.455

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-35
0.450

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1OC)c1cccnc1

LON-WEI-adc59df6-18
0.449

View
C=CC(=O)N(C)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

RAL-MED-9a5eb9cb-6
0.443

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-8f408cad-10
0.432

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC(C)(C)C)c1ccccn1

ERI-UCB-fbdd3ea1-25
0.431

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1Cl)c1cccnc1

LON-WEI-adc59df6-42
0.429

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(Cl)cc1F)c1cccnc1

LON-WEI-adc59df6-33
0.427

View
C=CC(=O)N(c1ccc(N(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

BRU-LEF-973da26b-1
0.425

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC(C)(C)C)c1cc[nH]c(=O)c1

ERI-UCB-fbdd3ea1-29
0.423

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-27
0.422

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCc1cccc(F)c1)c1cncc(C)c1

LON-WEI-babf2c61-13
0.421

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCc1cccc(F)c1)c1cncc(O)c1

LON-WEI-babf2c61-12
0.417

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Cl)c1C)c1cccnc1

LON-WEI-adc59df6-9
0.414

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1-c1ccccc1)c1cccnc1

LON-WEI-adc59df6-34
0.414

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-47
0.413

View
C=CC(=O)N(c1cc(C(C)(C)C#N)on1)[C@@H](C(=O)NC)c1cnccc1C

DAR-DIA-2b784ede-32
0.411

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-d1c9908a-9
0.411

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCc1cccc(F)c1)c1cncc(Cl)c1

LON-WEI-babf2c61-11
0.410

View
C=CC(=O)N(c1cc(C(C)(C)Cl)on1)[C@@H](C(=O)NC)c1cnccc1C

DAR-DIA-2b784ede-33
0.410

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-12
0.409

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1C)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-15
0.406

View
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)C(=O)CNCc1ccccc1)c1cc(C(C)(C)C)on1

ERI-UCB-fbdd3ea1-34
0.405

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CC1)c1cccnc1

LON-WEI-adc59df6-44
0.404

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NC(C)(C)C)c1cncc2ccccc12

ERI-UCB-fbdd3ea1-27
0.402

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-d1c9908a-5
0.402

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)nc1)c1cccnc1

LON-WEI-adc59df6-37
0.402

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-48
0.402

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC)c1cccnc1

LON-WEI-adc59df6-3
0.400

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-13
0.398

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCc1cccc(F)c1)c1cncc(C#N)c1

LON-WEI-babf2c61-14
0.397

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1)c1cccnc1

LON-WEI-adc59df6-46
0.396

View
C=CC(=O)N(c1cnc(OC)c(Br)c1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-84
0.394

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-20
0.393

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-19
0.393

View
C=CC(=O)N(c1cc(C(C)(C)C)nn1C(C)C)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-13
0.393

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-8f408cad-8
0.392

View
C=CC(=O)N(c1cc(C(C)(C)C#N)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-36
0.392

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(=O)OC)c1)c1cccnc1

LON-WEI-adc59df6-24
0.391

View
C=CC(=O)N(c1cc(C(C)(C)Cl)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-34
0.390

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1C(C)C)c1cccnc1

DAR-DIA-2b784ede-51
0.390

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-d1c9908a-10
0.389

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-d1c9908a-12
0.389

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1

LON-WEI-adc59df6-15
0.389

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-8f408cad-9
0.389

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCOC)c1cccnc1

LON-WEI-adc59df6-26
0.389

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)C)c1cccnc1

LON-WEI-adc59df6-21
0.388

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc2c(c1)OCO2)c1cccnc1

LON-WEI-adc59df6-43
0.388

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc2c(c1)OCCO2)c1cccnc1

LON-WEI-adc59df6-4
0.388

View
C#CCOc1ccc(N(C(=O)C=C)C(C(=O)NC(C)(C)C)c2cccnc2)cc1

LON-WEI-adc59df6-87
0.387

View
C=CC(=O)N(c1cc(C(C)(C)C)nn1C)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-11
0.387

View
C=CC(=O)N(c1ccc2ncsc2c1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-25
0.387

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-21
0.386

View
COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.484

View
COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.473

View
COC1=CC=C(NC(=O)NC(C)C2=CC=CN=C2)C(C)=C1

0.453

View
COC1=CC=C(NC(=O)NC(C2=CC=CN=C2)C(C)(C)CO)C(C)=C1

0.446

View
COC1=CC=C(NC(=O)NC(C2=CC=CC=C2)C2=CC=CN=C2)C(C)=C1

0.444

View
COC1=CC=C(NC(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.433

View
COC1=CC=C(NC(=O)C(=O)NC(C)C2=CC=CN=C2)C(C)=C1

0.433

View
COC1=CC=C(NC(=O)C(C)OC2=CC=CN=C2)C(C)=C1

0.432

View
COC1=CC=C(NC(=O)C(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.429

View
COC1=CC=C(NC(=O)C(=O)NC(C2=CC=CC=C2)C2=CC=CN=C2)C(C)=C1

0.426

View
COC1=CC=C(NC(=O)C(C2=CC=CC=C2)N(C)C)C(C)=C1

0.424

View
COC1=CC=C(NC(=O)C(=O)NC2=NOC(C(C)(C)C)=C2)C(C)=C1

0.421

View
COC1=CC=C(NC(=O)CC2=CC=CN=C2)C(C)=C1

0.419

View
COC1=CC=C(NC(=O)NCC(C2=CC=CN=C2)C(C)C)C(C)=C1

0.416

View
COC1=CC=C(NC(=O)NC(C2=CC=CN=C2)C2CCCCC2)C(C)=C1

0.413

View
COC1=CC=C(NC(=O)C2=NOC(C(C)(C)C)=C2)C(C)=C1

0.413

View
COC1=CC=C(NC(=O)C(C)(C)C2=CC=CN=C2)C(C)=C1

0.400

View
COC1=CC=C(NC(=O)N2CCN(C(C)C3=CC=CN=C3)CC2)C(C)=C1

0.400

View
COC1=CC=C(NC(=O)C(=O)NCC(C2=CC=CN=C2)C(C)C)C(C)=C1

0.398

View
COC1=CC=C(NC(=O)C2=CC=CN=C2)C(C)=C1

0.398

View
COC1=CC=C(NC(=O)C(=O)NC(C2=CC=CN=C2)C2CCCCC2)C(C)=C1

0.396

View
CCN(CC)C(C(=O)NC1=CC=C(OC)C=C1C)C1=CC=CC=C1

0.396

View
COC1=CC=C(NC(=O)C(C2=CC=CC(Cl)=C2)N(C)C)C(C)=C1

0.394

View
COC1=CC=C(NC(=O)C(=O)N2CCN(C(C)C3=CC=CN=C3)CC2)C(C)=C1

0.393

View
CCN(C)C(C(=O)NC1=CC=C(OC)C=C1C)C1=CC=CC=C1

0.392

View
COC1=CC=C(NC(=O)C2=C(C)ON=C2C2=CC=CN=C2)C(C)=C1

0.390

View
COC1=CC=C(NC(=O)NC2=CC=CN=C2)C(C)=C1

0.389

View
COC1=CC=C(NC(=O)NCC(C)(C)C2=CC=CN=C2)C(C)=C1

0.386

View
COC1=CC=C(NC(=O)C(=O)NC2=CC=CN=C2)C(C)=C1

0.385

View
COC1=CC=C(NC(=O)C=CC2=CC=CN=C2)C(C)=C1

0.384

View
C=CC(=O)NC1=CC=C(OC)C=C1C

0.384

View
COC1=CC=C(NC(=O)N2CCN(C3=CC=CN=C3)CC2)C(C)=C1

0.379

View
COC1=CC=C(NC(=O)NOCC2=CC=CN=C2)C(C)=C1

0.376

View
COC1=CC=C(NC(=O)C(=O)NCC2=CC=CN=C2)C(C)=C1

0.376

View
COC1=CC=C(NC(=O)C(=O)NCC(C)(C)C2=CC=CN=C2)C(C)=C1

0.375

View
COC1=CC=C(NC(=O)C(=O)NC(C)C2=CC=C(OC3=CC=CN=C3)C=C2)C(C)=C1

0.374

View
COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(O)=C1

0.374

View
COC1=CC=C(NC(=O)COC2=CC=CN=C2)C(C)=C1

0.371

View
COC1=CC=C(NC(=O)NCC2=CC=CN=C2)C(C)=C1

0.370

View
CC1=CC(OC(C)C)=CC=C1NC(=O)C(O)C1=CC=CN=C1

0.370

View
C=CCC(C(=O)NC1=CC=C(OC)C=C1C)C1=CC=CC=C1

0.370

View
CCN(CC1=CC=CN=C1)C(=O)NC1=CC=C(OC)C=C1C

0.369

View
CC1=CC(OC2=CC=CC=C2)=CC=C1NC(=O)C(O)C1=CC=CN=C1

0.369

View
COC1=CC=C(NC(=O)C(F)C2=CC=CC=C2)C(C)=C1

0.368

View
CCOC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.366

View
CC1=CC(OC(C)C)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.366

View
COCCOC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.365

View
COC1=CC=C(NC(=O)CCCOC2=CC=CN=C2)C(C)=C1

0.363

View
C=CCCC(C(=O)NC1=CC=C(OC)C=C1C)C1=CC=CC=C1

0.363

View
COC1=CC=C(NC(=O)CCCC2=CC=CN=C2)C(C)=C1

0.363

View
COC1=CC=C(NC(=O)N(C)CC2=CC=CN=C2)C(C)=C1

0.363

View
COC(=O)COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.362

View
COC1=CC=C(NC(=O)C(=O)NC2=CC=CC(Cl)=C2OC2=CC=CN=C2)C(C)=C1

0.361

View
COC1=CC=C(NC(=O)OC(C)(C)C)C(NC(=O)C(O)C2=CC=CN=C2)=C1

0.361

View
COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(OC)=C1

0.360

View
CC1=CC(OC(F)F)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.359

View
CCOC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.359

View
COCCOC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.358

View
CCN(CC1=CC=CN=C1)C(=O)C(=O)NC1=CC=C(OC)C=C1C

0.358

View
COC1=CC=C(NC(=O)C2(C3=CC=CN=C3)CC2)C(C)=C1

0.356

View
COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C(F)(F)F)=C1

0.356

View
COC1=CC=C(NC(=O)C(=O)NC2=CC=C(OC3=CC=CN=C3)C=C2)C(C)=C1

0.356

View
CCCOC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.356

View
COC1=CC=C(NC(=O)NCCOC2=CC=CN=C2)C(C)=C1

0.356

View
COC1=CC=C(NC(=O)C2=CC=C(OC3=CC=CN=C3)C=C2)C(C)=C1

0.353

View
COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(F)=C1

0.353

View
COC1=CC=C(NC(=O)C(=O)NC2=CC(C3=CC=CN=C3)=CC=C2C)C(C)=C1

0.352

View
CCCCOC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.352

View
COC1=CC=C(NC(=O)C(=O)NOCC2=CC=CN=C2)C(C)=C1

0.352

View
COC1=CC=C(NC(=O)C(F)F)C(C)=C1

0.352

View
COC1=CC=C(NC(=O)C(SC)C2=CC=CC=C2)C(C)=C1

0.351

View
CCCOC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.349

View
COC1=CC=C(NC(=O)N(CC2=CC=NC=C2)CC2=CC=CN=C2)C(C)=C1

0.349

View
COC1=CC=C(NC(=O)C(F)C(=O)NC2=CC=C(OC)C=C2C)C(C)=C1

0.348

View
COC1=CC=C(NC(=O)N(CC2=CC=CN=C2)CC2=CC=CO2)C(C)=C1

0.348

View
CCC(C(=O)NC1=CC=C(OC)C=C1C)C1=CC=CC=C1

0.347

View
COC(=O)C1=CC(OC)=CC=C1NC(=O)C(O)C1=CC=CN=C1

0.346

View
CCCCOC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.346

View
COC1=CC=C(NC(=O)CN(C)S(=O)(=O)C2=CC=CN=C2)C(C)=C1

0.346

View
COC1=CC=C(NC(=O)C2(C3=CC=CN=C3)CCCC2)C(C)=C1

0.343

View
COC1=CC=C(NC(=O)N2CCC(C3=CC=CN=C3)CC2)C(C)=C1

0.343

View
COC1=CC=C(NC(=O)C=CC2=CC=C(OC3=CC=CN=C3)C(F)=C2)C(C)=C1

0.342

View
CCC(C1=CC=CC(OC)=C1)N(C)C(=O)C(=O)NC1=NOC(C(C)(C)C)=C1

0.339

View
COC1=CC=C(NC(=O)N2CCC(C3=CC=CN=C3)C2)C(C)=C1

0.339

View
COCCN(CC1=CC=CN=C1)C(=O)NC1=CC=C(OC)C=C1C

0.339

View
C=CC(C)(CC)C(=O)NC1=CC=C(OC)C=C1C

0.337

View
CC1=CC(OC(F)F)=CC=C1NC(=O)N(C)C(C)C1=CC=CN=C1

0.336

View
CCC(F)C(=O)NC1=CC=C(OC)C=C1C

0.333

View
COC1=CC=C(NC(=O)C(=O)N2CCC(C3=CC=CN=C3)CC2)C(C)=C1

0.333

View
CC1=CC(OC(F)F)=CC=C1NC(=O)C(C)OC1=CC=CN=C1

0.327

View
COC1=CC=C(NC(=O)C2=CC=C(C3=CN=CC=N3)C=N2)C(C)=C1

0.321

View
CCC(CC(F)F)C(=O)NC1=CC=C(OC)C=C1C

0.316

View
CC1=CC(OC(F)F)=CC=C1NC(=O)C(C)(C)C1=CC=CN=C1

0.314

View
COC1=CC=C(OC(F)F)C(NC(=O)C(O)C2=CC=CN=C2)=C1

0.312

View
COC1=CC=CC(C(O)C(=O)NC2=CC(C3=CC=CN=C3)=CC=C2C)=C1

0.304

View
COC1=CC=C(C2=CC=CN=C2)C=C1NC(=O)C1=NOC(C(C)(C)C)=C1

0.304

View
CCC(F)C(=O)NC1=CC=C(OCC2=CC=CN=C2)C=C1C

0.303

View
COC1=CC=CC(C(C)C(=O)NC2=CC(C3=CC=CN=C3)=CC=C2C)=C1

0.301

View
CCC(C1=CC=CC(OC)=C1)N(C)C(=O)C(=O)NC1=CC(C2=CC=CN=C2)=CC=C1C

0.298

View
COC1=CC=C(C(C)C(=O)NC2=CC(C3=CC=CN=C3)=CC=C2C)C=C1

0.286

View


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