Molecule Details

C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1
3-aminopyridine-like Enamine Mcule MolPort Assayed
View on Fragalysis x2776
Molecular Properties
SMILES:
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1
MW: 459.546
Fraction sp3: 0.22
HBA: 5
HBD: 1
Rotatable Bonds: 9
TPSA: 80.76
cLogP: 5.00502
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine SCR: Z4438424255
Mcule: MCULE-3742892507
MolPort: MolPort-047-358-720
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 2.909986
Average Inhibition @ 50 µM - Fluorescence: 6.899891
Relative Solubility @ 20 µM: 0.99
Relative Solubility @ 100 µM: 0.97
Order Status
Shipped: 2020-04-09
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-d1c9908a-3
0.775

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-40
0.767

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-28
0.758

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-37
0.758

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-d1c9908a-4
0.742

View
C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-26
0.713

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-30
0.695

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-19
0.685

View
C=CC(=O)N(c1ccc2ncsc2c1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-1
0.641

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-10
0.633

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-45
0.633

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-22
0.632

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-b8d98729-17
0.620

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-43
0.610

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1OC)c1cccnc1

LON-WEI-adc59df6-45
0.600

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1C)c1cccnc1

LON-WEI-adc59df6-16
0.586

View
C=CC(=O)N(c1ccc(N(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

BRU-LEF-973da26b-1
0.546

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(OC)c1)c1cccnc1

LON-WEI-adc59df6-12
0.545

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-d1c9908a-7
0.535

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-47
0.530

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-27
0.525

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-12
0.525

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1OC)c1cccnc1

LON-WEI-adc59df6-18
0.525

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-d1c9908a-5
0.515

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1Cl)c1cccnc1

LON-WEI-adc59df6-42
0.505

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-8f408cad-10
0.505

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Cl)c1C)c1cccnc1

LON-WEI-adc59df6-9
0.500

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(Cl)cc1F)c1cccnc1

LON-WEI-adc59df6-33
0.500

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-d1c9908a-9
0.495

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1C)c1cccnc1

NIM-NMI-8bb27a2b-22
0.480

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-d1c9908a-13
0.477

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-41
0.476

View
C=CC(=O)N(c1ccc(C(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-80
0.474

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-b8d98729-36
0.473

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc(OC(F)(F)F)cc1)c1cccnc1

NIM-NMI-8bb27a2b-25
0.472

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1-c1ccccc1)c1cccnc1

LON-WEI-adc59df6-34
0.472

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)nc1)c1cccnc1

LON-WEI-adc59df6-37
0.472

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-d1c9908a-12
0.472

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-13
0.467

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)C)c1cccnc1

LON-WEI-adc59df6-21
0.464

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC)c1cccnc1

LON-WEI-adc59df6-3
0.463

View
C=CC(=O)N(c1ccc(NC(C)=O)cc1)[C@@H](C(=O)Nc1cccc(Cl)c1)c1cccnc1

JAN-GHE-d851b096-4
0.462

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(=O)OC)c1)c1cccnc1

LON-WEI-adc59df6-24
0.459

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-d1c9908a-10
0.458

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1Cl)c1cccnc1

NIM-NMI-8bb27a2b-21
0.454

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-2
0.454

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCCC(=O)OCC)c1cccnc1

LON-WEI-adc59df6-7
0.454

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC)c1cccnc1

RAL-MED-9a5eb9cb-10
0.454

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-8f408cad-8
0.454

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1)c1cccnc1

LON-WEI-adc59df6-46
0.453

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1)c1cccnc1

LON-WEI-adc59df6-41
0.452

View
C=CC(=O)N(c1ccc2ncsc2c1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-25
0.451

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccccc1)c1cccnc1

RAL-MED-9a5eb9cb-9
0.451

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CC1)c1cccnc1

LON-WEI-adc59df6-44
0.450

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-29
0.450

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-2
0.450

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-39
0.450

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)[C@H](C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-1
0.450

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccc(Br)cc1)c1cccnc1

LON-WEI-b8d98729-35
0.449

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Br)c1)c1cccnc1

LON-WEI-adc59df6-5
0.449

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-24
0.448

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCC(=O)OC)c1cccnc1

NIM-NMI-8bb27a2b-19
0.447

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCOC)c1cccnc1

LON-WEI-adc59df6-26
0.447

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-33
0.444

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCC)c1cccnc1

LON-WEI-adc59df6-30
0.444

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1

LON-WEI-adc59df6-15
0.444

View
C#CCOc1ccc(N(C(=O)C=C)C(C(=O)NC(C)(C)C)c2cccnc2)cc1

LON-WEI-adc59df6-87
0.443

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-d1c9908a-8
0.441

View
C=CC(=O)N(c1ccc(C(C)(C)C#N)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-82
0.441

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCC1)c1cccnc1

LON-WEI-adc59df6-14
0.441

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)CC)c1cccnc1

LON-WEI-adc59df6-31
0.441

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-7
0.440

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-6
0.440

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-4
0.440

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

RAL-MED-9a5eb9cb-12
0.440

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1ccc(Br)cc1)c1cccnc1

LON-WEI-d1c9908a-11
0.439

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCCOC)c1cccnc1

LON-WEI-adc59df6-27
0.438

View
C=CC(=O)N(c1ccccn1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

BRU-LEF-e1854a6f-1
0.438

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccccn1)c1cccnc1

BRU-LEF-8bac3ce8-1
0.438

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-d1c9908a-6
0.438

View
C=CC(=O)N(c1ccc(C(F)(F)CF)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-91
0.437

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCC(=O)OCC)c1cccnc1

LON-WEI-adc59df6-2
0.435

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-d1c9908a-2
0.435

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc2c(c1)CCC2)c1cccnc1

LON-WEI-adc59df6-11
0.434

View
C=CC(=O)N(C)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

RAL-MED-9a5eb9cb-6
0.433

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCCC(C)C)c1cccnc1

NIM-NMI-8bb27a2b-24
0.433

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCC1)c1cccnc1

LON-WEI-adc59df6-35
0.433

View
C=CC(=O)N(c1ccc(N2CCC2)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-95
0.433

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc2ccccc2c1)c1cccnc1

NIM-NMI-8bb27a2b-26
0.432

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC1CC1)c1cccnc1

NIM-NMI-8bb27a2b-17
0.431

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-d1c9908a-1
0.431

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(Br)cc1)c1cccnc1

LON-WEI-b8d98729-14
0.431

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-11
0.431

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OCc2ccccc2)cc1)c1cccnc1

LON-WEI-adc59df6-13
0.431

View
C=CC(=O)N(C(C(=O)Nc1ccc(OC)cc1)c1cccnc1)C(C)(C)C

RAL-MED-9a5eb9cb-14
0.430

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCC(=O)OCC)c1cccnc1

NIM-NMI-8bb27a2b-18
0.430

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc2c(c1)OCO2)c1cccnc1

LON-WEI-adc59df6-43
0.429

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc2c(c1)OCCO2)c1cccnc1

LON-WEI-adc59df6-4
0.429

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCc1cccnc1)c1cccnc1

LON-WEI-adc59df6-28
0.429

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(OCc2ccccc2)c1)c1cccnc1

LON-WEI-adc59df6-38
0.429

View
COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.495

View
COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.489

View
COC1=CC=C(NC(=O)C(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.463

View
COC1=CC=C(NC(=O)NC(C)C2=CC=CN=C2)C(C)=C1

0.457

View
COC1=CC=C(NC(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.453

View
COC1=CC=C(NC(=O)C(=O)NC(C)C2=CC=CN=C2)C(C)=C1

0.453

View
COC1=CC=C(NC(=O)NCC(C2=CC=CN=C2)C(C)C)C(C)=C1

0.449

View
COC1=CC=C(NC(=O)C(=O)NCC(C2=CC=CN=C2)C(C)C)C(C)=C1

0.444

View
COC1=CC=C(NC(=O)C(C)OC2=CC=CN=C2)C(C)=C1

0.436

View
COC1=CC=C(NC(=O)NC(C2=CC=CC=C2)C2=CC=CN=C2)C(C)=C1

0.434

View
COC1=CC=C(NC(C)C2=CC=CN=C2)C(C)=C1

0.433

View
COC1=CC=C(NC(=O)C(=O)NC(C2=CC=CC=C2)C2=CC=CN=C2)C(C)=C1

0.430

View
COC1=CC=C(NC(=O)CC2=CC=CN=C2)C(C)=C1

0.424

View
COC1=CC=C(NC(=O)C(=O)N2CCN(C(C)C3=CC=CN=C3)CC2)C(C)=C1

0.423

View
COC1=CC=C(NC(=O)N2CCN(C(C)C3=CC=CN=C3)CC2)C(C)=C1

0.417

View
COC1=CC=C(NC(=O)C(C2=CC=CC=C2)N(C)C)C(C)=C1

0.413

View
COC1=CC=C(NC(=O)C(C)C2=CC=NC=C2)C(C)=C1

0.413

View
COC1=CC=C(NC(=O)NC(C2=CC=CN=C2)C(C)(C)CO)C(C)=C1

0.408

View
COC1=CC=C(NC(=O)[C@@H](C)C2=CC=CC=C2)C(C)=C1

0.407

View
COC1=CC=C(NC(=O)[C@H](C)C2=CC=CC=C2)C(C)=C1

0.407

View
COC1=CC=C(NC(=O)C(C)C2=CC=CC=C2)C(C)=C1

0.407

View
COC1=CC=C(NC(=O)C(=O)NC2=CC=CN=C2)C(C)=C1

0.404

View
COC1=CC=C(NC(=O)C(=O)NC(C)C2=CC=C(OC3=CC=CN=C3)C=C2)C(C)=C1

0.404

View
COC1=CC=C(NC(=O)NC(C2=CC=CN=C2)C2CCCCC2)C(C)=C1

0.404

View
COC1=CC=C(NC(=O)C2=CC=CN=C2)C(C)=C1

0.402

View
COC1=CC=C(NC(=O)C=CC2=CC=CN=C2)C(C)=C1

0.402

View
CCN(CC)C(C(=O)NC1=CC=C(OC)C=C1C)C1=CC=CC=C1

0.400

View
COC1=CC=CC(C(C)C(=O)NC2=CC=C(OC)C=C2C)=C1

0.398

View
CCN(C)C(C(=O)NC1=CC=C(OC)C=C1C)C1=CC=CC=C1

0.396

View
COC1=CC=C(NC(=O)NC2=CC=CN=C2)C(C)=C1

0.394

View
CC1=CC(OC(C)C2=CC=CC=C2)=CC=C1NC(=O)C(O)C1=CC=CN=C1

0.388

View
CC1=CC(OC(C)C)=CC=C1NC(=O)C(O)C1=CC=CN=C1

0.388

View
CC1=CC(N(C)C)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.388

View
CC1=CC(OC(C)C)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.384

View
COC1=CC=C(NC(=O)C(C2=CC=CC(Cl)=C2)N(C)C)C(C)=C1

0.384

View
COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(O)=C1

0.384

View
COC1=CC=C(NC(=O)C(C)C2=CN=CC=N2)C(C)=C1

0.381

View
COC1=CC=C(NC(=O)CCCC2=CC=CN=C2)C(C)=C1

0.380

View
CC1=CC(OCC(=O)O)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.379

View
CCOC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.376

View
CC1=CC(OC(F)F)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.376

View
COCCOC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.375

View
COC1=CC=C(NC(=O)C(C)(C)C2=CC=CN=C2)C(C)=C1

0.375

View
CCN(CC1=CC=CN=C1)C(=O)NC1=CC=C(OC)C=C1C

0.373

View
C=CC(=O)NC1=CC=C(OC)C=C1C

0.372

View
COC(=O)COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.371

View
CCC(C)C(OC)C(=O)NC1=CC=C(OCC2=CC=CN=C2)C=C1C

0.371

View
COC1=CC=C(C(=O)OC(C)C2=CC=CN=C2)C(C)=C1

0.371

View
CCOC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.370

View
COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(Br)=C1

0.370

View
COC1=CC=C(NC(=O)C2=CC=C(OC3=CC=CN=C3)C=C2)C(C)=C1

0.370

View
COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(F)=C1

0.370

View
COCCOC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.369

View
COC1=CC=C(NC(=O)C(=O)NC2=CC(C3=CC=CN=C3)=CC=C2C)C(C)=C1

0.369

View
COC1=CC=C(NC(=O)C2=C(C)ON=C2C2=CC=CN=C2)C(C)=C1

0.368

View
COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(OC)=C1

0.366

View
CO[C@H](C)C(=O)NC1=CC=C(OCC2=CC=CN=C2)C=C1C

0.366

View
COC(C)C(=O)NC1=CC=C(OCC2=CC=CN=C2)C=C1C

0.366

View
COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(I)=C1

0.366

View
CCCOC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.365

View
COC1=CC=C(NC(=O)C(C)NC(C)C2=CC=CN=C2)C(OC)=C1

0.365

View
COC(=O)COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.365

View
COC1=CC=C(NC(=O)C(=O)NCC(=O)NC2=CC=CN=C2)C(C)=C1

0.365

View
CC1=CC(OCC2=CC=CN=C2)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.364

View
COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(OC)=C1

0.364

View
COC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(Br)=C1

0.364

View
CCCCOC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.362

View
CC1=CC(OC(C)C2=CC=CC=C2)=CC=C1NC(=O)C(C)OC1=CC=CN=C1

0.362

View
CCOC1=CC=C(NC(=O)C(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.362

View
CC1=CC(OCC2=CC=NC=C2)=CC=C1NC(=O)C(C1=CC=CN=C1)C(C)C

0.361

View
CCCOC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.359

View
COC1=CC=C(NC(=O)NCC(=O)NC2=CC=CN=C2)C(C)=C1

0.359

View
CC1=CC(OC(C)C)=CC=C1NC(=O)N(C)C(C)C1=CC=CN=C1

0.359

View
CCCCOC1=CC=C(NC(=O)C(O)C2=CC=CN=C2)C(C)=C1

0.356

View
CNC(=O)COC1=CC=C(NC(=O)C(C2=CC=CN=C2)C(C)C)C(C)=C1

0.355

View
CC1=CC(OC(C)C)=CC=C1NC(=O)NC(C)C1=CC=CN=C1

0.353

View
CCOC1=CC=C(NC(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.352

View
COC1=CC=C(NC(=O)C(C)SC(C)C2=CC=CN=C2)C(OC)=C1

0.352

View
COC(C(=O)NC1=CC=C(OCC2=CC=CN=C2)C=C1C)C(C)C

0.352

View
COCCOC1=CC=C(NC(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.352

View
CCCCOC1=CC=C(NC(=O)C(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.349

View
CCOC1=CC=C(NC(=O)NC(C)C2=CC=CN=C2)C(C)=C1

0.346

View
CC1=CC(OC(C)C2=CC=CC=C2)=CC=C1NC(=O)C1=CC=CN=C1

0.346

View
COC1=CC=C(NC(=O)C2=C[NH]N=C2C2=CC=CN=C2)C(C)=C1

0.346

View
COC1=CC=C(NC(=O)C2=CC=CC(NC(=O)C3=CC=CN=C3)=C2)C(C)=C1

0.346

View
CCOC1=CC=C(NC(=O)C(=O)NC(C)C2=CC=CN=C2)C(C)=C1

0.343

View
CCCOC1=CC=C(NC(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.343

View
COC1=CC=C(OC)C(NC(=O)C(C2=CC=CN=C2)C(C)C)=C1

0.340

View
COC1=CC=C(NC(=O)C2=CN(C)N=C2C2=CC=CN=C2)C(C)=C1

0.339

View
CCCCOC1=CC=C(NC(=O)N(C)C(C)C2=CC=CN=C2)C(C)=C1

0.339

View
COC1=CC=C(NC(=O)C(C)N2CCN(C(C)C3=CC=CN=C3)CC2)C(OC)=C1

0.339

View
COC1=CC=C(Cl)C(NC(=O)C(C2=CC=CN=C2)C(C)C)=C1

0.337

View
CCCCOC1=CC=C(NC(=O)NC(C)C2=CC=CN=C2)C(C)=C1

0.333

View
C=CC(=O)NC1=CC=C(OCC2=CC=CN=C2)C=C1C

0.333

View
COC1=CC=C(NC(=O)C2=CC=NC=C2Cl)C(C)=C1

0.333

View
COC1=CC=CC(C(C)C(=O)NC2=CC(C3=CC=CN=C3)=CC=C2C)=C1

0.327

View
COC1=CC=C(C(C)C(=O)NC2=CC(C3=CC=CN=C3)=CC=C2C)C=C1

0.324

View
COC1=CC=CC(C(C)C(=O)NC2=CC=NC=C2C)=C1

0.324

View
CCOC1=CC=C(NC(=O)N2CCN(C(C)C3=CC=CN=C3)CC2)C(C)=C1

0.319

View
COC1=CC=C(NC(=O)C(C)NC2=CC(C3=CC=CN=C3)=CC=C2C)C(OC)=C1

0.308

View
CC(C)(C)NC(=O)C(N(C(=O)C=C)c1ccc(cc1)C(C)(C)C)c1cccnc1

0.454

View


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