Molecule Details

Molecular Properties
SMILES:
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCC(=O)OCC)c1cccnc1
MW: 437.54
Fraction sp3: 0.36
HBA: 5
HBD: 1
Rotatable Bonds: 9
TPSA: 88.6
cLogP: 3.7088
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine SCR: Z4457849189
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 27.80088
Average Inhibition @ 50 µM - Fluorescence: 46.30419
Average Inhibition @ 20 µM - RapidFire: 12.319996132888
Average Inhibition @ 50 µM - RapidFire: 43.683379389046
Relative Solubility @ 20 µM: 0.99
Relative Solubility @ 100 µM: 0.97
Order Status
Shipped: 2020-05-13

Carboxylic acid esters

aliphatic ester, not lactones

Ester

Long aliphatic chain

C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCCC(=O)OCC)c1cccnc1

LON-WEI-adc59df6-7
0.831

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCC)c1cccnc1

LON-WEI-adc59df6-30
0.747

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCOC)c1cccnc1

LON-WEI-adc59df6-26
0.714

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCN(C)C)c1cccnc1

LON-WEI-adc59df6-29
0.711

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCCOC)c1cccnc1

LON-WEI-adc59df6-27
0.698

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCSC)c1cccnc1

LON-WEI-adc59df6-17
0.694

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCCSC)c1cccnc1

LON-WEI-adc59df6-10
0.670

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCC(=O)OCC)c1cccnc1

NIM-NMI-8bb27a2b-18
0.663

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC)c1cccnc1

LON-WEI-adc59df6-3
0.654

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCc1cccnc1)c1cccnc1

LON-WEI-adc59df6-28
0.648

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCN1CCCC1)c1cccnc1

LON-WEI-adc59df6-22
0.641

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-8f408cad-8
0.639

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCc1ccccc1)c1cccnc1

LON-WEI-adc59df6-40
0.633

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCc1ccncc1)c1cccnc1

LON-WEI-adc59df6-36
0.633

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)CC)c1cccnc1

LON-WEI-adc59df6-31
0.632

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)C)c1cccnc1

LON-WEI-adc59df6-21
0.631

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCc1cccc(F)c1)c1cccnc1

LON-WEI-adc59df6-47
0.628

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCN1CCOCC1)c1cccnc1

LON-WEI-adc59df6-25
0.621

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCc1ccc(Cl)cc1)c1cccnc1

LON-WEI-adc59df6-20
0.620

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCc1ccc(F)cc1)c1cccnc1

LON-WEI-adc59df6-23
0.613

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCCCC)c1cccnc1

NIM-NMI-8bb27a2b-16
0.611

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CC1)c1cccnc1

LON-WEI-adc59df6-44
0.609

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCC(=O)OC)c1cccnc1

NIM-NMI-8bb27a2b-19
0.600

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCCC(C)C)c1cccnc1

NIM-NMI-8bb27a2b-24
0.600

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCC1)c1cccnc1

LON-WEI-adc59df6-14
0.596

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCC1CCCO1)c1cccnc1

LON-WEI-adc59df6-32
0.594

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCC1CCOC1)c1cccnc1

LON-WEI-adc59df6-19
0.594

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCC(=O)OC(C)(C)C)c1cccnc1

NIM-NMI-8bb27a2b-23
0.591

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-d1c9908a-10
0.589

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1OC)c1cccnc1

LON-WEI-adc59df6-18
0.585

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCC1)c1cccnc1

LON-WEI-adc59df6-35
0.582

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1Cl)c1cccnc1

LON-WEI-adc59df6-42
0.582

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-d1c9908a-7
0.581

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Br)c1)c1cccnc1

LON-WEI-adc59df6-5
0.579

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)nc1)c1cccnc1

LON-WEI-adc59df6-37
0.573

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1)c1cccnc1

LON-WEI-adc59df6-41
0.570

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCCC1)c1cccnc1

LON-WEI-adc59df6-8
0.570

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CC(C(=O)OC)C1)c1cccnc1

LON-WEI-adc59df6-1
0.568

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1)c1cccnc1

LON-WEI-adc59df6-46
0.568

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-d1c9908a-3
0.561

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCOCC1)c1cccnc1

LON-WEI-adc59df6-39
0.558

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(OC)c1)c1cccnc1

LON-WEI-adc59df6-12
0.557

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Cl)c1C)c1cccnc1

LON-WEI-adc59df6-9
0.557

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(Cl)cc1F)c1cccnc1

LON-WEI-adc59df6-33
0.557

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-d1c9908a-9
0.551

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1C)c1cccnc1

LON-WEI-adc59df6-16
0.551

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC)c1cccnc1

RAL-MED-9a5eb9cb-10
0.545

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

ERI-UCB-fbdd3ea1-4
0.544

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

RAL-MED-9a5eb9cb-12
0.544

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1

LON-WEI-adc59df6-15
0.541

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-d1c9908a-12
0.541

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1-c1ccccc1)c1cccnc1

LON-WEI-adc59df6-34
0.541

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(=O)OC)c1)c1cccnc1

LON-WEI-adc59df6-24
0.540

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)N[C@H]1CC[C@@H](C(=O)OC)C1)c1cccnc1

LON-WEI-adc59df6-6
0.540

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCCc1cccc(F)c1)c1cccnc1

LON-WEI-babf2c61-9
0.540

View
C=CC(=O)N(c1ccc(C(F)(F)CF)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-91
0.538

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1OC)c1cccnc1

LON-WEI-adc59df6-45
0.535

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccc(Br)cc1)c1cccnc1

LON-WEI-b8d98729-35
0.531

View
C=CC(=O)N(c1ccc(C(C)(C)C#N)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-82
0.527

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCc1ccccc1)c1cccnc1

NIM-NMI-8bb27a2b-20
0.526

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc2c(c1)OCO2)c1cccnc1

LON-WEI-adc59df6-43
0.520

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc2c(c1)OCCO2)c1cccnc1

LON-WEI-adc59df6-4
0.520

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OCc2ccccc2)cc1)c1cccnc1

LON-WEI-adc59df6-13
0.519

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCc1ccc(Cl)cc1)c1cccnc1

NIM-NMI-8bb27a2b-28
0.515

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-10
0.511

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-33
0.510

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc2c(c1)CCC2)c1cccnc1

LON-WEI-adc59df6-11
0.510

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccccn1)c1cccnc1

BRU-LEF-8bac3ce8-1
0.505

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1C)c1cccnc1

NIM-NMI-8bb27a2b-22
0.505

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCc1cccc(Cl)c1)c1cccnc1

NIM-NMI-8bb27a2b-27
0.505

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-2
0.500

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)[C@H](C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-1
0.500

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC1CC1)c1cccnc1

NIM-NMI-8bb27a2b-17
0.500

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCC(=O)OCC)c1cccnc1

NIM-NMI-8bb27a2b-12
0.500

View
C=CC(=O)N(c1ccc(C(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-80
0.500

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(OCc2ccccc2)c1)c1cccnc1

LON-WEI-adc59df6-38
0.500

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-41
0.500

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-39
0.500

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-b8d98729-36
0.495

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-7
0.495

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-6
0.495

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-27
0.490

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccccc1)c1cccnc1

RAL-MED-9a5eb9cb-9
0.490

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(N)=O)c1cccnc1

RAL-MED-9a5eb9cb-11
0.489

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-d1c9908a-1
0.484

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc(OC(F)(F)F)cc1)c1cccnc1

NIM-NMI-8bb27a2b-25
0.480

View
C#CCOc1ccc(N(C(=O)C=C)C(C(=O)NC(C)(C)C)c2cccnc2)cc1

LON-WEI-adc59df6-87
0.480

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC1CCCC1)c1cccnc1

RAL-MED-9a5eb9cb-15
0.480

View
C=CC(=O)N(c1ccc(CC)c(I)c1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-73
0.479

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-37
0.476

View
CC(C)(C)c1ccc(N(C(=O)c2cccnc2)C(C(=O)NCCc2cccc(F)c2)c2cccnc2)cc1

LON-WEI-2e27a2e5-2
0.476

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1Cl)c1cccnc1

NIM-NMI-8bb27a2b-21
0.476

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)(C)C)c1cncc(OCC)c1

LON-WEI-adc59df6-57
0.474

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCCc1cccc(F)c1)c1cncc(C)c1

LON-WEI-babf2c61-2
0.471

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-19
0.471

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC1CCCCC1)c1cccnc1

NIM-NMI-8bb27a2b-15
0.470

View
C=CC(=O)N(c1ccc(CCC#N)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-78
0.470

View
C=CC(=O)N(c1ccc(N2CCC2)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-95
0.469

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)NCCCC)c1cccnc1

NIM-NMI-8bb27a2b-2
0.465

View
CC(C)(C)NC(=O)C(c1cccnc1)N(C(=O)c1ccco1)c1ccc(C(C)(C)C)cc1

ALP-POS-c59291d4-6
0.464

View
CCOC(=O)CCNC(=O)C(O)C1=CC=CN=C1

0.506

View
CCOC(=O)CCNC(=O)C(C1=CC=CN=C1)C(C)C

0.471

View
CCOC(=O)CCNC(=O)C(C)(C)C1=CC=CN=C1

0.427

View
CCOC(=O)CCCNC(=O)C(O)C1=CC=CN=C1

0.422

View
CCOC(=O)CCN(C)C(C(=O)OC)C1=CC=CN=C1

0.418

View
CCOC(=O)CCNC(=O)C(N)C1=CC=C(C(C)(C)C)C=C1

0.414

View
CCOC(=O)CCNC(C)C1=CC=CN=C1

0.414

View
CCOC(=O)CCNC(=O)CC1=CC=CN=C1

0.414

View
CCOC(=O)CCNC(C1=CC=CN=C1)C(C)(C)CO

0.413

View
CC(OC(=O)CCNC(=O)C1=CC=C(C(C)(C)C)C=C1)C1=CC=CN=C1

0.411

View
CCOC(=O)CCNC(=O)C1=CC=CN=C1

0.407

View
CCOC(=O)CCNC(=O)C(C)OC1=CC=CN=C1

0.407

View
CCCOC(=O)CCNC(=O)C(O)C1=CC=CN=C1

0.407

View
CCOC(=O)CCNC(=O)C(C)NC(=O)C1=CC=C(C(C)(C)C)C=C1

0.407

View
CCOC(=O)CCNC(=O)C(NC(=O)C1=CC=C(C(C)(C)C)C=C1)C(C)C

0.402

View
CCOC(=O)CCNC(=O)C(C)=CC1=CC=CN=C1

0.400

View
CCOC(=O)CCNC(C1=CC=CC=C1)C1=CC=CN=C1

0.398

View
CCOC(=O)CCNC(=O)C(C1=CC=CC=C1)N(C)C

0.398

View
CCOC(=O)CCCNC(=O)C(C1=CC=CN=C1)C(C)C

0.394

View
CCOC(=O)CNC(=O)C(O)C1=CC=CN=C1

0.393

View
CCOC(=O)CCNC(=O)C(C1=CC=CC=C1)N(CC)CC

0.389

View
CCOC(=O)CCNC(=O)C(C1=CC=CC=C1)N(C)CC

0.389

View
CCOC(=O)CCNC(=O)NC1=CC=CN=C1

0.389

View
CCOC(=O)CCNC(=O)C1=CC=C(C(C)(C)C)C=C1

0.388

View
CCOC(=O)NCCC(=O)OC(C)C1=CC=CN=C1

0.387

View
CCOC(=O)C(NC(=O)C1=CC=C(C(C)(C)C)C=C1)C(O)C1=CC=CN=C1

0.385

View
CCOC(=O)CCNC(=O)C(C)OC1=CC=C(C(C)(C)C)C=C1

0.385

View
CC(C)(C)OC(=O)CCNC(=O)C(O)C1=CC=CN=C1

0.385

View
CCOC(=O)CN(C)C(C(=O)OC)C1=CC=CN=C1

0.385

View
CC(OC(=O)CCNS(=O)(=O)C1=CC=C(C(C)(C)C)C=C1)C1=CC=CN=C1

0.384

View
CCOC(=O)CCCNC(=O)CN(C)C(C)C1=CC=CN=C1

0.384

View
CCOC(=O)CCCNC(C1=CC=CN=C1)C(C)(C)CO

0.381

View
CCOC(=O)CCNC(=O)C=CC1=CC=CN=C1

0.380

View
CCCOC(=O)CCNC(=O)C(C1=CC=CN=C1)C(C)C

0.379

View
CCOC(=O)CCCNC(=O)N(C)C(C)C1=CC=CN=C1

0.378

View
CCOC(=O)CCCNC(=O)CNC(C)C1=CC=CN=C1

0.378

View
CCOC(=O)CCNC(=O)CCCC1=CC=CN=C1

0.376

View
COC(=O)CCNC(=O)C(O)C1=CC=CN=C1

0.375

View
CCOC(=O)CCN(CC1=CC=CN=C1)C(=O)C1=CC=C(C(C)(C)C)C=C1

0.374

View
CCOC(=O)CCC(=O)N(C)C(C)C1=CC=CN=C1

0.374

View
CCOC(=O)CCNC(=O)C=CC1=CC=C(C(C)(C)C)C=C1

0.374

View
CCOC(=O)CCNC(=O)C(C1=CC=CC(Cl)=C1)N(C)C

0.372

View
CCOC(=O)CCCNC(=O)NC(C)C1=CC=CN=C1

0.371

View
CCOC(=O)CCN(CC1=CC=CN=C1)C(=O)CC1=CC=C(C(C)(C)C)C=C1

0.370

View
CCOC(=O)CCNC(=O)CCC1=CC=CN=C1

0.370

View
C=CCC(C(=O)NCCC(=O)OCC)C1=CC=CC=C1

0.370

View
CCOC(=O)CCCNC(C)C1=CC=CN=C1

0.370

View
CCOC(=O)CCC(=O)NCC(C1=CC=CN=C1)C(C)C

0.368

View
CCOC(=O)CCCNC(=O)C(C)(C)C1=CC=CN=C1

0.368

View
CCOC(=O)CCC(=O)NCC(C)(C)C1=CC=CN=C1

0.366

View
CCOC(=O)CCNC(=O)CCC(O)C1=CC=C(C(C)(C)C)C=C1

0.366

View
C=CCN(CC(=O)OCC)C(=O)C(O)C1=CC=CN=C1

0.365

View
CCOC(=O)CCNC(=O)CCNS(=O)(=O)C1=CC=CN=C1

0.365

View
CCOC(=O)CCNC(=O)C(C)(C)C1=CC=C(C(C)(C)C)C=C1

0.364

View
CC(C1=CC=CN=C1)N(C)C(=O)CCNC(=O)C1=CC=C(C(C)(C)C)C=C1

0.364

View
CC(C)(C)C1=CC=C(C(=O)NCCC(=O)OCC(=O)NC2=CC=CN=C2)C=C1

0.363

View
CCOC(=O)CCNC(=O)CCNC(=O)C1=CC=C(C(C)(C)C)C=C1

0.363

View
CCOC(=O)CCN(C)C(=O)C(O)C1=CC=CN=C1

0.362

View
CCOC(=O)CCCCNC(C)C1=CC=CN=C1

0.362

View
CCOC(=O)CCNC(=O)C(F)C1=CC=CC=C1

0.360

View
CCOC(=O)CCNC(=O)CSC1=CC=C(C(C)(C)C)C=C1

0.359

View
CC(C)C(C(=O)NCCC(=O)OC(C)(C)C)C1=CC=CN=C1

0.358

View
CCOC(=O)CCCCCNC(C)C1=CC=CN=C1

0.358

View
CC(C)(C)C1=CC=C(C(=O)NCCC(=O)OCC2=CC=CN=C2)C=C1

0.357

View
CCOC(=O)CCCNC(C1=CC=CC=C1)C1=CC=CN=C1

0.357

View
C=CC(=O)N(CCC(=O)OCC)CC1=CC=CN=C1

0.354

View
C=CCCC(C(=O)NCCC(=O)OCC)C1=CC=CC=C1

0.354

View
CCOC(=O)CCNC(=O)COCC1=CC=CN=C1

0.354

View
CCOC(=O)CCNC(=O)CCC1=CC=C(C(C)(C)C)C=C1

0.352

View
CN(C(=O)C(O)C1=CC=CN=C1)C1=CC=C(C(C)(C)C)C=C1

0.352

View
CC(C)(C)C1=CC=C(CCNC(=O)C(O)C2=CC=CN=C2)C=C1

0.351

View
CCOC(=O)CCS(=O)(=O)NC(C)C1=CC=CN=C1

0.351

View
CC(C)(C)C1=CC=C(OCCNC(=O)C(O)C2=CC=CN=C2)C=C1

0.351

View
CCOC(=O)CCS(=O)(=O)NC(C1=CC=CN=C1)C(C)(C)CO

0.350

View
CCOC(=O)CCC(=O)COC(=O)C(O)C1=CC=CN=C1

0.347

View
CCOC(=O)CCC(=O)NC(C1=CC=CC=C1)C1=CC=CN=C1

0.347

View
C=CCN(CC(=O)OCC)CC(O)C1=CC=CN=C1

0.347

View
CCOC(=O)CCN(CC1=CC=CN=C1)C(=O)C=CC1=CC=C(C(C)(C)C)C=C1

0.346

View
CCOC(=O)CCNC(=O)C(F)C1=CC=C(C(F)(F)F)C=C1

0.344

View
CCOC(=O)CCC(=O)NC(C(=O)OC)C1=CC=CN=C1

0.344

View
CCOC(=O)CCS(=O)(=O)N(C)C(C)C1=CC=CN=C1

0.344

View
CCOC(=O)CCNC(=O)CCNS(=O)(=O)C1=CC=C(C(C)(C)C)C=C1

0.344

View
CCOC(=O)CCCNC(=O)C(N)C1=CC=C(C(C)(C)C)C=C1

0.340

View
CC(C)C(C(=O)NCCC1=CC=C(C(C)(C)C)C=C1)C1=CC=CN=C1

0.337

View
CCOC(=O)CCNC(=O)C1=CC=C(C2=CC=C(C(C)(C)C)C=C2)O1

0.337

View
CC(C)C(C(=O)NCCOC1=CC=C(C(C)(C)C)C=C1)C1=CC=CN=C1

0.337

View
CC(C)(C)C1=CC=C(C(N)C(=O)NCCC(=O)NC2=CC=CN=C2)C=C1

0.337

View
CCOC(=O)CCN(CC1=CC=CN=C1)S(=O)(=O)C1=CC=C(C(C)(C)C)C=C1

0.333

View
CC(C)(C)C1=CC=C(C(=O)NCCC(=O)NC(CO)C2=CC=CN=C2)C=C1

0.333

View
CCOC(=O)NCCC(=O)OC(C1=CC=CC=C1)C1=CC=CN=C1

0.333

View
CC(C)(C)C1=CC=C(C(=O)NCCC(=O)NCC(O)C2=CC=CN=C2)C=C1

0.333

View
CC(C1=CC=CN=C1)N(C)C(=O)NCCC(=O)OC(C)(C)C

0.333

View
CCOC(=O)COCCNC(=O)C(C1=CC=CN=C1)C(C)C

0.330

View
CCOC(=O)CN(CC)C(=O)C(O)C1=CC=CN=C1

0.330

View
CC(OC1=CC=C(C(C)(C)C)C=C1)C(=O)NC(CO)C1=CC=CN=C1

0.327

View
CCOC(=O)CCNC(=O)NC1=CC=NN1CC1=CC=C(C(C)(C)C)C=C1

0.321

View
CC(C)(C)C1=CC=C(C(N)C(=O)NCCC(=O)NCC2=CC=CN=C2)C=C1

0.314

View
CC(OC1=CC=C(C(C)(C)C)C=C1)C(=O)NC(C)C1=CC=CN=C1

0.313

View
CC(OC1=CC=C(C(C)(C)C)C=C1)C(=O)NCCC(=O)NC1=CC=CN=C1

0.311

View
CCOC(=O)C(C(=O)NCCC(=O)NC1=CC=CN=C1)C1=CC=CC=C1

0.299

View
CC(C)(C)NC(=O)C(N(C(=O)C=C)c1ccc(cc1)C(C)(C)C)c1cccnc1

0.639

View


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