Molecule Details

C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1
3-aminopyridine-like Enamine Mcule MolPort Assayed
View on Fragalysis x2703
Molecular Properties
SMILES:
C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1
MW: 442.563
Fraction sp3: 0.26
HBA: 4
HBD: 1
Rotatable Bonds: 8
TPSA: 75.19
cLogP: 5.36982
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine SCR: Z4439011588
Mcule: MCULE-5280742139
MolPort: MolPort-047-366-043
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 5.6132675
Average Inhibition @ 50 µM - Fluorescence: 12.477995
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 0.95
Order Status
Shipped: 2020-04-09
C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)Nc1c(CC)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-53
0.761

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-d1c9908a-10
0.711

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-2
0.703

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-45
0.699

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-2
0.696

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-29
0.696

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-39
0.696

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)[C@H](C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-1
0.696

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-42
0.681

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-d1c9908a-8
0.681

View
C=CC(=O)N(c1ccc2ncsc2c1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-48
0.644

View
C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-b8d98729-32
0.636

View
C=CC(=O)N(c1ccc(C(C)C)nc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-26
0.622

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-46
0.596

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

LON-WEI-b8d98729-20
0.584

View
CCC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

ERI-UCB-fbdd3ea1-3
0.561

View
C=CC(=O)N(c1cc(C(C)(C)C#N)n[nH]1)C(C(=O)Nc1c(C)cccc1CC)c1cccnc1

DAR-DIA-2b784ede-42
0.557

View
C=CC(=O)N(c1ccc(CCl)nc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-7
0.556

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1C)c1cccnc1

NIM-NMI-8bb27a2b-22
0.552

View
C=CC(=O)N(c1ccc(CC#N)nc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-11
0.545

View
C=CC(=O)N(c1ccc(CCl)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-9
0.535

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1c(C)cccc1Cl)c1cccnc1

NIM-NMI-8bb27a2b-21
0.520

View
C=CC(=O)N(c1ccc(CC#N)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-10
0.519

View
C=CC(=O)N(c1ccc(C2(Cl)CCCC2)nc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-18
0.505

View
C=CC(=O)N(c1ccc(C2(C#N)CCCC2)nc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-14
0.491

View
C=CC(=O)N(c1ccc(C2(Cl)CCCC2)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-16
0.491

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-48
0.491

View
C=CC(=O)N(c1cc2c(s1)CCCC2)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-46
0.482

View
C=CC(=O)N(c1cc(C(C)(C)Cl)n[nH]1)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-45
0.482

View
C=CC(=O)N(c1ccc(C2(C#N)CCCC2)cc1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-15
0.478

View
C=CC(=O)N(c1ccc(CCl)cn1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-8
0.477

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1C)c1cccnc1

NIM-NMI-8bb27a2b-6
0.466

View
C=CC(=O)N(c1ccc(CC)c(I)c1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-73
0.465

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-b8d98729-16
0.464

View
C=CC(=O)N(c1ccc(CC#N)cn1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-12
0.459

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-b8d98729-17
0.455

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(C)cccc1C(C)C)c1cccnc1

DAR-DIA-2b784ede-51
0.450

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-35
0.450

View
C=CC(=O)N(c1cnc(N(C)C)nc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-70
0.449

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1c(C)cccc1CO)c1cnccc1C

DAR-DIA-2b784ede-38
0.449

View
C=CC(=O)N(c1ccc(C2(C)CC2)cc1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-d1c9908a-6
0.445

View
C=CC(=O)N(c1ccc(NC(C)=O)cc1)[C@@H](C(=O)Nc1cccc(Cl)c1)c1cccnc1

JAN-GHE-d851b096-4
0.442

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NCC)c1cccnc1

LON-WEI-adc59df6-30
0.439

View
C=CC(=O)N(c1cc(C(C)(C)Cl)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-34
0.438

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(CC)cccc1CCO)c1cccnc1

DAR-DIA-2b784ede-50
0.438

View
C=CC(=O)N(c1cc(C(C)(C)C)on1)C(C(=O)Nc1c(C)cccc1Cl)c1cccnc1

NIM-NMI-8bb27a2b-7
0.436

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)CC)c1cccnc1

LON-WEI-adc59df6-31
0.436

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1)c1cccnc1

LON-WEI-adc59df6-46
0.434

View
C=CC(=O)N(c1cc(C(C)(C)C)n[nH]1)C(C(=O)Nc1c(CC)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-52
0.432

View
C=CC(=O)N(c1ccc(C2(Cl)CCCC2)cn1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-17
0.431

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Br)c1)c1cccnc1

LON-WEI-adc59df6-5
0.430

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccc(Br)cc1)c1cccnc1

LON-WEI-b8d98729-35
0.430

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)C)c1cccnc1

LON-WEI-adc59df6-21
0.429

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-b8d98729-36
0.429

View
C=CC(=O)N(c1ccc2ncsc2c1)C(C(=O)Nc1cccc(CC)c1)c1cccnc1

LON-WEI-b8d98729-38
0.427

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(=O)OC)c1)c1cccnc1

LON-WEI-adc59df6-24
0.427

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccccc1Cl)c1cccnc1

LON-WEI-adc59df6-42
0.427

View
C=CC(=O)N(c1cccc(Cl)c1)C(C(=O)Nc1cccc(Cl)c1)c1cccnc1

JAN-GHE-d851b096-9
0.427

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC)c1cccnc1

LON-WEI-adc59df6-3
0.427

View
C=CC(=O)N(c1cc(C(C)(C)C#N)on1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-36
0.426

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-11
0.426

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-33
0.426

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(C(F)(F)F)c1)c1cccnc1

LON-WEI-adc59df6-15
0.426

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(Cl)c1C)c1cccnc1

LON-WEI-adc59df6-9
0.426

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(OC)c1)c1cccnc1

LON-WEI-adc59df6-12
0.426

View
C=CC(=O)N(c1ccc(C(C)(C)CC)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-d1c9908a-12
0.426

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(Br)cc1)c1cccnc1

LON-WEI-b8d98729-14
0.426

View
C=CC(=O)N(c1ccc(C(F)F)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-adc59df6-80
0.424

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-8
0.423

View
C=CC(=O)N(c1ccc(N(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

BRU-LEF-973da26b-1
0.423

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-13
0.422

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1C)c1cccnc1

LON-WEI-adc59df6-16
0.422

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(F)c1C)c1cccnc1

LON-WEI-d1c9908a-9
0.422

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCC1)c1cccnc1

LON-WEI-adc59df6-14
0.422

View
C=CC(=O)N(c1ccc(C2(C#N)CCCC2)cn1)[C@@H](C(=O)Nc1c(C)cccc1CC)c1cnccc1C

DAR-DIA-2b784ede-13
0.420

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(F)cc1)c1cccnc1

LON-WEI-adc59df6-41
0.419

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccccn1)c1cccnc1

BRU-LEF-8bac3ce8-1
0.419

View
C=CC(=O)N(C1CC2(CCCC2)CN1)C(C(=O)Nc1c(C)cccc1CO)c1cccnc1

DAR-DIA-2b784ede-44
0.419

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-8f408cad-8
0.418

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NC)c1cccnc1

RAL-MED-9a5eb9cb-10
0.418

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-d1c9908a-3
0.418

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1c(CC)cccc1CO)c1cnccc1C

DAR-DIA-2b784ede-39
0.418

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-8f408cad-10
0.418

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)Nc1ccccc1)c1cccnc1

RAL-MED-9a5eb9cb-9
0.417

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccccc1Br)c1cccnc1

LON-WEI-b8d98729-19
0.417

View
C=CC(=O)N(c1ccc(C(C)OC)cc1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-22
0.417

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CC1)c1cccnc1

LON-WEI-adc59df6-44
0.416

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-d1c9908a-7
0.415

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1ccc(Cl)cc1)c1cccnc1

LON-WEI-b8d98729-24
0.415

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-40
0.414

View
C=CC(=O)N(c1ccc(N(C)C)c(C)c1)C(C(=O)NC(C)(C)C)c1cccnc1

LON-WEI-8f408cad-9
0.413

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCCC(C)C)c1cccnc1

NIM-NMI-8bb27a2b-24
0.413

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)NC1CCCC1)c1cccnc1

LON-WEI-adc59df6-35
0.413

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(OC)nc1)c1cccnc1

LON-WEI-adc59df6-37
0.413

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1ccc(Cl)cc1F)c1cccnc1

LON-WEI-adc59df6-33
0.413

View
C=CC(=O)N(c1ccc(C(C)(C)C)cc1)C(C(=O)Nc1cccc(OCc2ccccc2)c1)c1cccnc1

LON-WEI-adc59df6-38
0.412

View
C=CC(=O)N(c1ccc(SC)cc1)C(C(=O)Nc1ccc(OC)cc1)c1cccnc1

LON-WEI-b8d98729-47
0.411

View
C=CC(=O)N(c1ccc(C(F)(F)F)cc1)C(C(=O)NCC(=O)OCC)c1cccnc1

NIM-NMI-8bb27a2b-18
0.411

View
C#CCOc1ccc(N(C(=O)C=C)C(C(=O)NC(C)(C)C)c2cccnc2)cc1

LON-WEI-adc59df6-87
0.411

View
C=CC(=O)N(c1ccc(S(F)(F)(F)(F)F)cc1)C(C(=O)Nc1ccc(OC)cc1C)c1cccnc1

LON-WEI-b8d98729-28
0.411

View
CCC1=CC=CC(C)=C1NC(=O)C(O)C1=CC=CN=C1

0.489

View
CCC1=CC=CC(C)=C1NC(=O)CN(C)C(C)C1=CC=CN=C1

0.458

View
CCC1=CC=CC(C)=C1NC(=O)N(C)C(C)C1=CC=CN=C1

0.457

View
CCC1=CC=CC(C)=C1NC(=O)C1=CC=C(C(C)C)N=C1

0.456

View
CCC1=CC=CC(C)=C1NC(=O)NC(C)C1=CC=CN=C1

0.452

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)N(C)C(C)C1=CC=CN=C1

0.448

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C)C1=CC=CN=C1

0.447

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC(C)C1=CC=CN=C1

0.447

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C(C1=CC=CN=C1)C(C)C

0.434

View
CCC1=CC=CC(C)=C1NC(=O)CSC(C)C1=CC=CN=C1

0.433

View
CCC1=CC=CC(C)=C1NC(=O)NCC(C1=CC=CN=C1)C(C)C

0.433

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NCC(C1=CC=CN=C1)C(C)C

0.429

View
CCC1=CC=CC(C)=C1NC(=O)C1=CC=CN=C1

0.427

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C1=CC=CN=C1)C(C)(C)CO

0.426

View
CCC1=CC=CC(C)=C1NC(=O)C(C)OC1=CC=CN=C1

0.426

View
CCC1=CC=CC(C)=C1NC(=O)NC(C1=CC=CN=C1)C(C)(C)CO

0.424

View
CCC1=CC=CC(C)=C1NC(=O)N1CCN(C(C)C2=CC=CN=C2)CC1

0.422

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C1=CN=CC=N1

0.419

View
CCC1=CC=CC(C)=C1NC(=O)NC(C1=CC=CC=C1)C1=CC=CN=C1

0.418

View
CCC1=CC=CC(C)=C1NNC(=O)C(C1=CC=CN=C1)C(C)C

0.417

View
CCC1=CC=CC(C)=C1NC(=O)CN(C)CC(O)C1=CC=CN=C1

0.416

View
CCC1=CC=CC(C)=C1NC(=O)CC1=CC=CN=C1

0.416

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)N1CCN(C(C)C2=CC=CN=C2)CC1

0.413

View
CCC1=CC=CC(C)=C1NNC(=O)C(=O)NC1=CC=C(C(C)C)N=C1

0.412

View
CCC1=CC=CC(C)=C1NNC(=O)C(O)C1=CC=CN=C1

0.411

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C(O)C1=CC=CN=C1

0.410

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C1=CC=C(C(C)C)N=C1

0.410

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC(C1=CC=CC=C1)C1=CC=CN=C1

0.410

View
CCC1=CC=CC(C)=C1NNC(=O)NC(C)C1=CC=CN=C1

0.408

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C1=CC=NC=C1

0.407

View
CCC1=CC=CC(C)=C1NNC(=O)NCC(C1=CC=CN=C1)C(C)C

0.406

View
CCC1=CC=CC(C)=C1NC(=O)COC1=CC=CN=C1

0.404

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC(C1=CC=CN=C1)C1CCCCC1

0.400

View
CCC1=CC=CC(C)=C1NC(=S)NNC(=O)C1=CC=C(C(C)C)N=C1

0.400

View
CCC1=CC=CC(C)=C1NC(=O)CN1CCN(C(C)C2=CC=CN=C2)CC1

0.396

View
CCC1=CC=CC(C)=C1NC(=O)CN1C=CN=C1C(O)C1=CC=CN=C1

0.393

View
CCC1=CC=CC(C)=C1NC(=O)CCCC1=CC=CN=C1

0.392

View
C=CC(O)C(=O)NC1=C(C)C=CC=C1CC

0.391

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C

0.390

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC(C)CC1=CC=CN=C1

0.390

View
CCC1=CC=CC(C)=C1NC(=O)N1CCN(C2=CC=CN=C2)CC1

0.390

View
CCC1=CC=CC(C)=C1NNC(=O)C1=CC=C(C(C)C)N=C1

0.389

View
CCC1=CC=CC(C)=C1NC(=O)[C@H](C)C1=CC=CC=C1

0.389

View
CCC1=CC=CC(C)=C1NC(=O)C(C)C1=CC=CC=C1

0.389

View
CCC1=CC=CC(C)=C1NC(=O)[C@@H](C)C1=CC=CC=C1

0.389

View
C=CCC(CC=C)C(=O)NC1=C(C)C=CC=C1CC

0.382

View
CCC1=CC=CC(C)=C1NC(=O)C=CC1=CC=CN=C1

0.381

View
CCC1=CC=CC(C)=C1NC(=O)NC(C)CC1=CC=CN=C1

0.380

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C1=CC=CN=C1)C1CCCCC1

0.380

View
CCC1=CC=CC(C)=C1NC(=O)C1=CC=C(C(F)F)N=C1

0.379

View
CCC1=CN=CC=C1C(C)NCC(=O)NC1=C(C)C=CC=C1CC

0.376

View
CCC1=CC=CC(C)=C1NC(=O)CCC1=CC=CN=C1

0.375

View
CCC1=CC=CC(C)=C1NC(=O)C(F)C1=CC=CC=C1

0.374

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C)CC1=CC=CN=C1

0.373

View
CCC1=CC=CC(C)=C1NC(=O)NC1=CC(C(C)C)=N[NH]1

0.371

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NC(C)C1=CC=C(OC2=CC=CN=C2)C=C1

0.370

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)NC(C)C1=CC=CN=C1

0.368

View
CCC1=CC=CC(C)=C1NC(=O)C(C)CN(C)C

0.367

View
CCC1=CC=CC(C)=C1NC(=O)CN(C)CC1=CC=CN=C1

0.366

View
COC(=O)C(C1=CC=CN=C1)N(C)CC(=O)NC1=C(C)C=CC=C1C

0.366

View
CCC1=CC=CC(C)=C1NC(=S)NNC(=O)C(C)C1=CN=CC=N1

0.365

View
CCC1=CC=CC(C)=C1NC(=O)CN(C)C(C)C1=CC=C(Cl)C=N1

0.365

View
CCC1=CC=CC(C)=C1NC(=O)C(F)F

0.365

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)OC(=O)C(C1=CC=CN=C1)C(C)C

0.364

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)N(C)CC(O)C1=CC=CN=C1

0.364

View
CCC1=CC=CC(C)=C1NC(=O)CSC(C)C1=CN=CC=N1

0.363

View
CCC1=CC=CC(C)=C1NC(=O)C(=O)NCC(C)(C)C1=CC=CN=C1

0.363

View
CCC1=CC=CC(C)=C1NC(=O)CN(CC)CC1=CC=CN=C1

0.363

View
CCC1=CC=CC(C)=C1NC(=O)CC(C)C1=CC=NC=C1

0.361

View
CCC1=CC=CC(C)=C1NC(=O)CSCC1=CC=CN=C1

0.360

View
CCC1=CC=CC(C)=C1NC(=O)COCC1=CC=CN=C1

0.356

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)NC(C1=CC=CC=C1)C1=CC=CN=C1

0.356

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C)C1=CN=CC=C1C

0.356

View
CCC1=CC=CC(C)=C1NC(=O)NCC(C)(C)C1=CC=CN=C1

0.356

View
CCC1=CC=CC(C)=C1NC(=O)CN1C=NC(C(C)C)=CC1=O

0.356

View
CCC1=CC=CC(C)=C1NC(=O)CS(=O)C(C)C1=CN=CC=N1

0.356

View
CCC1=CC=CC(C)=C1NC(=O)CS(=O)(=O)C(C)C1=CN=CC=N1

0.356

View
CCC1=CC=CC(C)=C1NC(=O)N1CCN(C2=CN=CC=N2)CC1

0.356

View
CCC1=CC=CC(C)=C1NC(=O)CN(CC1=CC=CN=C1)C1=CC=CC=C1

0.355

View
CCC1=CC=CC(CC)=C1NC(=O)N(C)C(C)C1=CC=CN=C1

0.354

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C)C1=CC=C(OCC2=CC=CN=C2)C=C1

0.354

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)N1CCN(C(C)C2=CC=CN=C2)CC1

0.353

View
CCC1=CC=CC(C)=C1NC(=O)N1CCC(C2=CC=CN=C2)CC1

0.352

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C)CCCC1=CC=CN=C1

0.352

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)OC(=O)C(O)C1=CC=CN=C1

0.350

View
CCC1=CC=CC(C)=C1NC(=O)CN1C=NC(C(C)C)=C1

0.350

View
CCC1=CC=CC(C)=C1NC(=O)CNC(C)C1=CC=C(Br)C=N1

0.350

View
CCN(CC(=O)NC1=C(C)C=CC=C1C)C(C(=O)OC)C1=CC=CN=C1

0.350

View
CCC1=CC=CC(C)=C1NC(=O)CN1C=CN=C1C(=O)C1=CC=CN=C1

0.349

View
CCC1=CC=CC(CC)=C1NC(=O)NC(C)C1=CC=CN=C1

0.347

View
CCC1=CC=CC(CC)=C1NC(=O)C(=O)N(C)C(C)C1=CC=CN=C1

0.347

View
CCC1=CC=CC(CC)=C1NC(=O)C(=O)NC(C)C1=CC=CN=C1

0.344

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C(C)(C)C1=CC=CN=C1

0.343

View
CCC1=CC=CC(C)=C1NC(=S)NNC(=O)C(C)(C)C1=CC=CN=C1

0.343

View
CCC1=CC=CC(C)=C1NC(=O)COC(=O)C1=CC=C(C(F)F)N=C1

0.343

View
CCC1=CC=CC(C)=C1NC(=O)CN1C=CN=CC1=O

0.340

View
CCC1=CC=CC(C)=C1NC(=O)CN1N=CC=C1C1=CC=CN=C1

0.333

View
CCC1=CC=CC(C)=C1NC(=O)CN1C=CN=C1C(C)C

0.333

View
CC1=C(NC(=O)CNC(C)C2=CC=CN=C2)C(C)=CC=C1

0.330

View
CCC1=CC=CC(CC)=C1NC(=O)C(C)OC(=O)C(C)(C)C1=CC=CN=C1

0.301

View

C(N(C(CN1C2=C(C=C(C)C=C2)CCC1)=O)C1=CC=CN=C1)(=O)C1=CN=C(C(C)(C)C)C=C1

0.702

View
C(N(C(CN1C2=C(C=CC=C2)CC1C)=O)C1=CC=CN=C1)(=O)C1=CN=C(C(C)(C)C)C=C1

0.700

View


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