Molecule Details

COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12
quinolones Enamine Assayed
View on Fragalysis x10525
Molecular Properties
SMILES:
COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12
MW: 370.13
Fraction sp3: 0.2
HBA: 4
HBD: 2
Rotatable Bonds: 6
TPSA: 80.42
cLogP: 2.87
Covalent Warhead:
Covalent Fragment:
Source
Enamine REAL: Z1275020238
Enamine Extended REAL: s_22____6108748____5350556
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 19.848885
Average Inhibition @ 50 µM - Fluorescence: 46.10182
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 0.99
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-06-16
CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

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COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-38
0.711

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COc1ccccc1OCC(C)NC(=O)c1cc(=O)[nH]c2ccc(F)cc12

MAT-POS-590ac91e-41
0.578

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COc1cccc2c1OCC(NC(=O)c1cc(=O)[nH]c3ccc(F)cc13)C2

MAT-POS-590ac91e-35
0.461

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O=C(NCC1COc2ccccc2O1)c1cc(=O)[nH]c2ccc(F)cc12

MAT-POS-590ac91e-30
0.455

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CC1(C)Cc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccc(F)cc34)c2O1

MAT-POS-590ac91e-47
0.453

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccc(Cl)cc12

MAT-POS-590ac91e-42
0.439

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COc1ccccc1OCC(C)NC(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-40
0.420

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-32
0.414

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12

MAT-POS-916a2c5a-2
0.402

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COc1ccccc1OCC(CC(C)C)NC(=O)c1cc(=O)[nH]c2ccccc12

DAR-DIA-8e329c92-6
0.400

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CCOc1ccccc1OC1CCN(C(=O)c2cc(=O)[nH]c3ccc(F)cc23)C1

MAT-POS-590ac91e-48
0.400

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CN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2ccc(F)cc12

MAT-POS-590ac91e-33
0.388

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COc1ccccc1NCCNC(=O)c1cc(=O)[nH]c2ccccc12

MAR-UCB-f313ec4d-4
0.384

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COc1ccccc1OCC(NC(=O)c1cc(=O)[nH]c2ccccc12)C1CC1

DAR-DIA-8e329c92-4
0.382

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COc1ccccc1OCC(NC(=O)c1cc(=O)[nH]c2ccccc12)N1CCC1

DAR-DIA-8e329c92-5
0.381

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O=C(c1cc(=O)[nH]c2ccc(F)cc12)N1CCN(S(=O)(=O)c2ccccc2Cl)CC1

MAT-POS-590ac91e-68
0.369

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COc1ccccc1OCC(NC(=O)c1cc(=O)[nH]c2ccccc12)N1CCCCC1

DAR-DIA-8e329c92-7
0.367

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COc1ccccc1OCC(CN1CCOCC1)NC(=O)c1cc(=O)[nH]c2ccccc12

DAR-DIA-8e329c92-8
0.363

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COc1ccccc1OCCN(C)C(=O)c1cc(=O)[nH]c2ccc(Cl)cc12

MAT-POS-590ac91e-43
0.356

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COc1ccccc1O[C@H]1CC[C@@H]1NC(=O)c1cc(=O)[nH]c2ccccc12

MAT-UCB-70f7c0f7-4
0.353

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COc1ccc(Cl)cc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12

ALP-POS-05819dc4-1
0.352

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O=C(c1cc(=O)[nH]c2ccc(F)cc12)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAT-POS-590ac91e-56
0.350

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cccc(F)c12

EDJ-MED-6af13d92-2
0.346

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COc1ccccc1OCCN(C)C(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-37
0.346

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N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)c2cc(=O)[nH]c3ccc(F)cc23)CC1

MAT-POS-590ac91e-62
0.339

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COc1ccccc1O[C@H]1CCCC[C@H]1NC(=O)c1cc(=O)[nH]c2ccccc12

ADA-UCB-b1b30a00-2
0.336

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COc1ccccc1O[C@H]1CCC[C@@H]1NC(=O)c1cc(=O)[nH]c2ccccc12

MAT-UCB-70f7c0f7-3
0.336

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COc1ccccc1OCCN(C)C(=O)c1cc(=O)[nH]c2ccccc12

BEN-DND-7e92b6ca-2
0.333

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cccc(OC)c12

EDJ-MED-6af13d92-3
0.330

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COc1ccccc1OC1CCCN(C(=O)c2cc(=O)[nH]c3ccc(Cl)cc23)C1

MAT-POS-590ac91e-54
0.327

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COc1ccccc1OC1CCN(C(=O)c2cc(=O)[nH]c3ccccc23)C1

ERI-UCB-a0b0dbcb-6
0.327

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COc1c(Cl)cccc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12

ALP-POS-3fc1724e-1
0.327

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O=C(c1cc(=O)[nH]c2ccc(F)cc12)N1CCN(S(=O)(=O)c2cccc(Cl)c2)CC1

MAT-POS-590ac91e-69
0.327

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COc1cccc(NCNC(=O)c2cc(=O)[nH]c3ccccc23)c1

DAR-DIA-8e329c92-10
0.327

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CC1(C)Cc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccc(Cl)cc34)c2O1

MAT-POS-590ac91e-53
0.325

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4ccc(F)cc34)CC2)c(C)c1

MAT-POS-590ac91e-64
0.324

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cccc(C)c12

EDJ-MED-6af13d92-1
0.321

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O=C(c1cc(=O)[nH]c2ccc(F)cc12)N1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

MAT-POS-590ac91e-67
0.321

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CC(=O)NCCc1c(O)[nH]c2ccc(F)cc12

SAN-PRS-3c4a6997-5
0.319

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COc1cccc2c1OCC(NC(=O)c1cc(=O)[nH]c3cc(F)ccc13)C2

MAT-POS-590ac91e-36
0.319

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N#Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4ccc(F)cc34)CC2)cc1

MAT-POS-590ac91e-59
0.312

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COc1ccccc1OC1CN(C(=O)c2cc(=O)[nH]c3ccccc23)C1

ERI-UCB-a0b0dbcb-9
0.308

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O=C(NCCNc1ccccc1)c1cc(=O)[nH]c2ccccc12

BEN-DND-7e92b6ca-4
0.306

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CC1(C)Cc2cccc(OCCNC(=O)c3cc(=O)[nH]c4cc(F)ccc34)c2O1

MAT-POS-590ac91e-46
0.305

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CN(CCNC(=O)c1cc(=O)[nH]c2ccccc12)c1ccccc1

BEN-DND-7e92b6ca-3
0.304

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O=C(NCCOc1ccccc1)c1cc(=O)[nH]c2ccccc12

BEN-DND-7e92b6ca-5
0.303

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O=C(NCCOc1cccc2c1CCCC2)c1cc(=O)[nH]c2ccccc12

MAT-UCB-70f7c0f7-1
0.301

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COc1ccc(Cl)cc1OCCN(C)C(=O)c1cc(=O)[nH]c2ccccc12

BEN-DND-b89db3f2-5
0.300

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O=C(NCC1COc2ccccc2O1)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-31
0.300

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CC(C)[C@H](O)C(=O)NCCc1c[nH]c2ccc(F)cc12

NAU-LAT-81109c57-1
0.296

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COc1ccccc1OCCN(C(=O)c1cc(=O)[nH]c2ccccc12)c1cccc(Cl)c1

ALP-POS-fc6c627f-3
0.296

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COc1ccccc1OCCC(=O)Nc1cc(=O)[nH]c2ccccc12

MAR-UCB-f313ec4d-1
0.295

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COc1ccccc1N1CCN(C(=O)c2cc(=O)[nH]c3ccccc23)CC1

BEN-DND-7e92b6ca-13
0.295

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COC(=O)c1c(NCCCc2ccccc2)c2cc(F)ccc2[nH]c1=O

LON-WEI-4d77710c-14
0.290

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COC(=O)c1c(NCCCc2ccccc2)c2cc(F)ccc2[nH]c1=O

MAT-POS-b5746674-78
0.290

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C[C@H](C(=O)O)c1ccc2c(c1)[nH]c1ccc(F)cc12

MAK-UNK-0d6072ac-1
0.287

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Cn1c(=O)n(CCNC(=O)c2cc(=O)[nH]c3ccccc23)c2ccccc21

ADA-UCB-b1b30a00-1
0.287

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CCOc1ccccc1OC1CCN(C(=O)c2cc(=O)[nH]c3cc(F)ccc23)C1

MAT-POS-590ac91e-49
0.287

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O=C1CCC(Oc2cc(Cl)cc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-18
0.286

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COc1ccccc1OCCNC(=O)c1cc(N)cc2ccccc12

DAR-DIA-8e329c92-2
0.286

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O=C1CCC(Oc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-14
0.284

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COc1ccccc1NC1CN(C(=O)c2cc(=O)[nH]c3ccccc23)C1

ERI-UCB-a0b0dbcb-8
0.282

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COc1ccccc1NC1CCN(C(=O)c2cc(=O)[nH]c3ccccc23)C1

ERI-UCB-a0b0dbcb-5
0.281

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O=C(NCCOc1cccc2c1OCCC2)c1cc(=O)[nH]c2ccccc12

MAT-UCB-70f7c0f7-2
0.277

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COc1ccccc1CN[C@H](C(=O)Nc1cc(=O)[nH]c2ccccc12)c1cccc(Cl)c1

ADA-UCB-6c2cb422-10
0.277

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O=C(NCCc1cccc2ccccc12)c1cc(=O)[nH]c2ccccc12

DAR-DIA-8e329c92-9
0.276

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O=C(NCCOc1cccc(Oc2cccc(=O)[nH]2)c1)c1cc(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-15
0.276

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O=C(NCCOc1cc(Cl)cc(Oc2cccnc2)c1)c1cc(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-20
0.275

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CN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-34
0.274

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COc1cc(Cl)cc(CN2CCN(C(=O)c3cc(=O)[nH]c4ccccc34)CC2)c1F

ALP-POS-3fc1724e-4
0.271

View
COc1ccccc1OC[C@H](C(=O)Nc1cc(=O)[nH]c2ccccc12)c1cccc(Cl)c1

ADA-UCB-6c2cb422-8
0.271

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COc1ccccc1OCCNC(=O)c1cc(N)nc2ccccc12

DAR-DIA-8e329c92-1
0.271

View
NS(=O)(=O)c1ccc(CCNC(=O)c2cc(=O)[nH]c3ccccc23)c2ccccc12

DAR-DIA-8e329c92-11
0.270

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COc1ccc(Cl)cc1CC(=O)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-3b92565d-4
0.269

View
CN1CCN(c2ccc(NC(=O)c3cc(=O)[nH]c4ccccc34)cc2)CC1

KRI-MAR-d2e3ef86-15
0.269

View
COc1ccc(Cl)cc1CC(=O)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-e1b5ac6b-2
0.269

View
CN1CCCc2c(S(N)(=O)=O)ccc(CCNC(=O)c3cc(=O)[nH]c4ccccc34)c21

DAR-DIA-8e329c92-13
0.268

View
NS(=O)(=O)c1ccc(CCNC(=O)c2cc(=O)[nH]c3ccccc23)c2c1CCCC2

DAR-DIA-8e329c92-12
0.267

View
O=C(NCCOc1cc(Cl)cc(Oc2cccc(=O)[nH]2)c1)c1cc(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-19
0.267

View
O=C1CC(Oc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-13
0.265

View
COc1ccccc1OCCNC(=O)c1cc(O)cc2ccccc12

DAR-DIA-8e329c92-3
0.264

View
COc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4cc(F)ccc34)CC2)cc1

MAT-POS-590ac91e-65
0.263

View
CC(=O)NCCc1c[nH]c2ccc(F)cc12

AAR-POS-d2a4d1df-2
0.263

View
O=C(NCCOc1cccc(Oc2cccnc2)c1)c1cc(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-16
0.263

View
COc1ccccc1OCCNC(=O)c1cc[nH]c(=O)c1

BEN-DND-7e92b6ca-1
0.263

View
COc1ccc2c(C(=O)N(CCc3cccc(OC)c3OC)c3cccc(Cl)c3)cc(=O)[nH]c2c1

ALP-POS-19e898d3-1
0.262

View
CCN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2ccc(Cl)cc12

MAT-POS-590ac91e-51
0.261

View
O=C1CC(Oc2cc(Cl)cc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ALP-POS-3fc1724e-2
0.261

View
O=C1CC(Oc2cc(Cl)cc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-17
0.261

View
O=C(c1cc(=O)[nH]c2ccccc12)N1CCN(c2ccc(F)cc2)CC1

BEN-DND-7e92b6ca-14
0.260

View
O=C(c1cc(=O)[nH]c2ccccc12)N1CCN(c2cccc(F)c2)CC1

BEN-DND-7e92b6ca-15
0.259

View
O=C(c1cc(=O)[nH]c2ccc(Cl)cc12)N1CCN(S(=O)(=O)c2ccccc2F)CC1

MAT-POS-590ac91e-70
0.259

View
CCCN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-50
0.256

View
CCCN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2ccc(Cl)cc12

MAT-POS-590ac91e-55
0.256

View
COc1ccccc1CO[C@H](C(=O)Nc1cc(=O)[nH]c2ccccc12)c1cccc(Cl)c1

ADA-UCB-6c2cb422-11
0.256

View
CCN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2ccc([N+](=O)[O-])cc12

MAT-POS-590ac91e-52
0.250

View
CC(=O)OCCc1c[nH]c2ccc(F)cc12

SAN-PRS-3c4a6997-4
0.250

View
COc1ccccc1OCCNC(=O)c1c(C#N)c(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-25
0.248

View
COc1ccc(N2CCN(C(=O)c3cc(=O)[nH]c4ccccc34)CC2)cc1

BEN-DND-7e92b6ca-11
0.248

View
O=C(Nc1ccccc1N1CCCCC1)c1cc(=O)[nH]c2ccccc12

KRI-MAR-d2e3ef86-12
0.248

View
COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

1.000

View
COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.846

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccccc1Cl

0.830

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccccc1F

0.827

View
Cc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.811

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccccc1Br

0.796

View
COc1ccccc1OCC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.782

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccccc1

0.755

View
COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2ccc([N+](=O)[O-])cc12

0.754

View
COc1cccc(OC(C)CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)c1

0.745

View
COc1ccccc1OC(C)CNC(=O)c1cc(F)cc2c(=O)c3cc(F)ccc3[nH]c12

0.741

View
COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.741

View
COc1ccc(OC(C)CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)cc1

0.741

View
COC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.725

View
COc1ccccc1C(O)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.719

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccc(F)cc1

0.717

View
COc1ccccc1C(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)OC(C)C

0.712

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1cccc(F)c1

0.709

View
COc1ccccc1C(=O)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.709

View
COc1ccccc1CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.709

View
CC(CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12)Oc1ccccc1Cl

0.702

View
COc1ccccc1OC(C)CNC(=O)c1[nH]c2ccc(F)cc2c1Cl

0.702

View
COc1ccccc1SCC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.700

View
CC(C)Oc1ccccc1CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.696

View
CC(CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12)Oc1ccccc1F

0.696

View
COc1ccccc1OC(C)CNC(=O)c1cc(F)ccc1OC

0.692

View
COc1cc(CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)ccc1OC(C)C

0.690

View
COc1ccccc1OCCCNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.690

View
COc1ccc(C(O)CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)cc1OC

0.690

View
COc1ccccc1CCNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.684

View
Cc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.684

View
COC(=O)C(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Cc1ccccc1OC

0.683

View
COc1ccccc1OC(C)CNC(=O)c1ccc(F)cc1F

0.679

View
COc1ccccc1OC(C)CNC(=O)c1cc(F)ccc1F

0.679

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccc(C(C)C)cc1

0.679

View
Cc1ccc(OC(C)CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)cc1

0.679

View
COc1ccc(CC(C)CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)cc1OC

0.678

View
CC(O)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.673

View
C[C@@H](O)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.673

View
C[C@H](O)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.673

View
Cc1cccc(OC(C)CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)c1

0.672

View
CC(CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12)Oc1ccccc1Br

0.672

View
COc1ccccc1C(=O)NNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.667

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccc(Cl)cc1

0.667

View
COc1ccccc1OC(C)CNC(=O)c1cc(F)ccc1C

0.667

View
COc1ccccc1OC(C)CNC(=O)c1ccc(F)cc1C

0.667

View
CC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.667

View
COc1ccccc1C(C)NC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.667

View
COc1ccccc1NC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.667

View
COc1ccccc1Oc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)cc1

0.667

View
COc1ccccc1OC(C)CNC(=O)c1ccc(F)cc1Cl

0.667

View
COc1ccccc1OC(C)CNC(=O)c1cc(F)ccc1Cl

0.667

View
CCC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccccc1Cl

0.667

View
C[C@@H](CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccc(Cl)cc1

0.667

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccc(Br)cc1

0.667

View
COc1ccccc1C(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)N1CCCC1

0.661

View
COc1ccccc1C(C)(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.661

View
CCC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccccc1F

0.661

View
COc1ccccc1C1(CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)CC1

0.661

View
COc1ccccc1OCC(C)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.661

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1cccc(Br)c1

0.661

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1cccc(Cl)c1

0.661

View
COc1cc(OC)c(OC)cc1CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.661

View
COc1ccccc1OC(C)CNC(=O)c1cc2cc(F)ccc2[nH]1

0.661

View
COc1ccccc1OC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.660

View
COC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)OC

0.660

View
COc1ccccc1CCNC(=O)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.656

View
COC(=O)C(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)c1ccccc1

0.655

View
CC(C)Oc1ccccc1NC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.655

View
COc1ccccc1OC(C)CNC(=O)c1cc(F)ccc1Br

0.655

View
COc1ccccc1OC(C)CNC(=O)c1ccc(F)cc1I

0.655

View
COC(=O)C(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.655

View
COc1ccccc1OC(C)CNC(=O)c1cc(F)ccc1O

0.655

View
COc1ccccc1OC(C)CNC(=O)c1cc(F)ccc1I

0.655

View
COC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)C(C)C

0.655

View
CC(C)C(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)c1ccccc1

0.655

View
COCC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.655

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)c1ccccc1

0.655

View
COc1ccccc1OC(C)CNC(=O)c1ccc(F)cc1Br

0.655

View
COc1ccccc1OC(C)CNC(=O)c1ccc(F)cc1O

0.655

View
COCC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)C(C)C

0.655

View
COc1ccccc1C(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)N1CCCCC1

0.651

View
COc1ccccc1-c1ccc(C(C)NC(=O)c2cc(=O)[nH]c3ccc(F)cc23)cc1

0.650

View
CCC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1ccccc1C

0.650

View
COc1ccccc1CC(NC(=O)c1cc(=O)[nH]c2ccc(F)cc12)C(C)C

0.650

View
COc1cc(NC(=O)c2cc(=O)[nH]c3ccc(F)cc23)ccc1OC(C)C

0.649

View
COc1ccc(NC(=O)c2cc(=O)[nH]c3ccc(F)cc23)cc1OC(C)C

0.649

View
COc1ccc(CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)cc1OC

0.649

View
COC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)c1ccccc1

0.649

View
COc1ccccc1OC(C)CNC(=O)c1ccc(F)cc1NC(C)=O

0.649

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)c1ccc(F)cc1

0.648

View
CC(C)COc1ccccc1CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.644

View
COc1ccccc1OCC(=O)NNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.644

View
COc1cccc(CNC(=O)c2cc(=O)[nH]c3ccc(F)cc23)c1OC

0.644

View
CC(C)c1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.644

View
COc1cccc(Cl)c1CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.644

View
COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2c(Br)cccc12

0.644

View
COc1ccccc1OC(C)CNC(=O)c1cc(C)nc2cc(F)ccc12

0.644

View
COc1cc(C(C)NC(=O)c2cc(=O)[nH]c3ccc(F)cc23)ccc1OC(C)C

0.644

View
COc1ccc(F)cc1CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.643

View
Cc1cccc(C)c1OC1CN(C(=O)c2cc(=O)n(C)c3ccccc23)C1

0.199

View
CCOc1ccccc1CN(CC)C(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.199

View
CC1CN(C(=O)c2cc(=O)[nH]c3ccc(F)cc23)CCO1

0.185

View
O=C(NCC(O)COc1ccccc1)c1cc(=O)[nH]c2ccccc12

0.184

View
Cc1ccc2[nH]c(=O)cc(C(=O)N3CC(Oc4ccccc4C)C3)c2c1

0.179

View
Cc1ccccc1OC1CN(C(=O)c2cc(=O)[nH]c3cc(F)ccc23)C1

0.172

View
CCc1cccc(OC2CN(C(=O)c3cc(=O)[nH]c4ccccc34)C2)c1

0.163

View
Cc1ccc(OCCNC(=O)c2cc(=O)[nH]c3ccccc23)cc1

0.158

View
CN(CCOc1ccc(OCc2ccccc2)cc1)C(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.151

View
Cc1ccc(C)c(OCCN(C)C(=O)c2cc(=O)[nH]c3ccc(F)cc23)c1

0.147

View
COc1ccccc1OC1CN(C(=O)c2cc(=O)n(C)c3ccccc23)C1

0.142

View
CN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2ccccc12

0.141

View
O=C(NCC1COc2ccccc2O1)c1cc(=O)[nH]c2ccccc12

0.123

View
COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12

0.116

View
CC(CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12)Oc1cccnc1

0.105

View
C(NCCOC1=C(OC)C=CC=C1)(=O)C1C2C(=CC=CC=2)N=CC=1

0.820

View
C(NCCOC1=C(OC)C=CC=C1)(=O)C1C2C(=NC=CC=2)C=CC=1

0.797

View
C(N(CCOC1=C(OC)C=CC=C1)C)(=O)C1C2C(=CC=CC=2)N=CC=1

0.781

View
C(NCCOC1=C(OC)C=CC=C1)(=O)C1=C2C(NC=C2)=CC=C1

0.775

View
C(NCCOC1=C(OC)C=CC=C1)(=O)C1C2=C(C=CC=C2)N=C(OC)C=1

0.771

View


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