Molecule Details

COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12
quinolones Enamine Assayed
View on Fragalysis x10355
Molecular Properties
SMILES:
COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12
MW: 356.12
Fraction sp3: 0.16
HBA: 4
HBD: 2
Rotatable Bonds: 6
TPSA: 80.42
cLogP: 2.48
Covalent Warhead:
Covalent Fragment:
Source
Enamine REAL: Z1245862555
Enamine Extended REAL: s_22____58494____5448680
Activity Data
IC50 (µM) - Fluorescence: 99.5
Trypsin IC50 (µM): 99.0
Average Inhibition @ 20 µM - Fluorescence: -6.6025105
Average Inhibition @ 50 µM - Fluorescence: 51.684445
Average Inhibition @ 50 µM - RapidFire: 9.6412694085
Relative Solubility @ 20 µM: 0.88
Relative Solubility @ 100 µM: 0.66
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-06-10

Aliphatic long chain

CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12

MAT-POS-916a2c5a-2
0.696

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COc1ccccc1OCC(C)NC(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-40
0.628

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COc1ccccc1OCCN(C)C(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-37
0.624

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccc(Cl)cc12

MAT-POS-590ac91e-42
0.616

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COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-38
0.609

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CC1(C)Cc2cccc(OCCNC(=O)c3cc(=O)[nH]c4cc(F)ccc34)c2O1

MAT-POS-590ac91e-46
0.600

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cccc(F)c12

EDJ-MED-6af13d92-2
0.586

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cccc(OC)c12

EDJ-MED-6af13d92-3
0.570

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COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cccc(C)c12

EDJ-MED-6af13d92-1
0.551

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COc1ccc(Cl)cc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12

ALP-POS-05819dc4-1
0.505

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COc1ccccc1OCCNC(=O)c1cc(O)cc2ccccc12

DAR-DIA-8e329c92-3
0.500

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COc1ccccc1OCCNC(=O)c1cc(N)cc2ccccc12

DAR-DIA-8e329c92-2
0.494

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COc1c(Cl)cccc1OCCNC(=O)c1cc(=O)[nH]c2ccccc12

ALP-POS-3fc1724e-1
0.489

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COc1ccccc1OCCNC(=O)c1cc(N)nc2ccccc12

DAR-DIA-8e329c92-1
0.489

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COc1ccccc1OCCNC(=O)c1cc[nH]c(=O)c1

BEN-DND-7e92b6ca-1
0.482

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O=C(NCC1COc2ccccc2O1)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-31
0.469

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COc1cccc2c1OCC(NC(=O)c1cc(=O)[nH]c3cc(F)ccc13)C2

MAT-POS-590ac91e-36
0.455

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COc1ccccc1OCCNC(=O)c1cncc2ccccc12

MAR-UCB-f313ec4d-2
0.451

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COc1ccccc1OCC(C)NC(=O)c1cc(=O)[nH]c2ccc(F)cc12

MAT-POS-590ac91e-41
0.443

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O=C(NCCOc1ccccc1)c1cc(=O)[nH]c2ccccc12

BEN-DND-7e92b6ca-5
0.443

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O=C(NCCOc1cccc2c1CCCC2)c1cc(=O)[nH]c2ccccc12

MAT-UCB-70f7c0f7-1
0.436

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COc1ccccc1OCCN(C)C(=O)c1cc(=O)[nH]c2ccccc12

BEN-DND-7e92b6ca-2
0.426

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COc1ccccc1OCC(CC(C)C)NC(=O)c1cc(=O)[nH]c2ccccc12

DAR-DIA-8e329c92-6
0.423

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COc1ccccc1NCCNC(=O)c1cc(=O)[nH]c2ccccc12

MAR-UCB-f313ec4d-4
0.421

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CC1(C)Cc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccc(F)cc34)c2O1

MAT-POS-590ac91e-47
0.421

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COc1ccccc1OCC(NC(=O)c1cc(=O)[nH]c2ccccc12)C1CC1

DAR-DIA-8e329c92-4
0.418

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COc1ccccc1OCCNC(=O)c1c(C#N)c(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-25
0.418

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CCOc1ccccc1OC1CCN(C(=O)c2cc(=O)[nH]c3cc(F)ccc23)C1

MAT-POS-590ac91e-49
0.417

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COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

MAT-POS-590ac91e-39
0.414

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CN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-34
0.406

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COc1ccccc1OCC(NC(=O)c1cc(=O)[nH]c2ccccc12)N1CCC1

DAR-DIA-8e329c92-5
0.402

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O=C(NCCOc1cccc2c1OCCC2)c1cc(=O)[nH]c2ccccc12

MAT-UCB-70f7c0f7-2
0.402

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CCCN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2cc(F)ccc12

MAT-POS-590ac91e-50
0.394

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O=C(NCCOc1cccc(Oc2cccc(=O)[nH]2)c1)c1cc(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-15
0.390

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COc1ccccc1OCCN(C)C(=O)c1cc(=O)[nH]c2ccc(Cl)cc12

MAT-POS-590ac91e-43
0.390

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O=C1CCC(Oc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-14
0.387

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COc1ccccc1OCC(NC(=O)c1cc(=O)[nH]c2ccccc12)N1CCCCC1

DAR-DIA-8e329c92-7
0.387

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COc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4cc(F)ccc34)CC2)cc1

MAT-POS-590ac91e-65
0.379

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O=C1CC(Oc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-13
0.377

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COc1ccccc1OCCN(C(=O)c1cc(=O)[nH]c2ccccc12)c1cccc(Cl)c1

ALP-POS-fc6c627f-3
0.374

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O=C(NCCOc1cccc(Oc2cccnc2)c1)c1cc(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-16
0.374

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O=C1CCC(Oc2cc(Cl)cc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-18
0.373

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O=C(c1cc(=O)[nH]c2cc(F)ccc12)N1CCN(S(=O)(=O)c2ccccc2)CC1

MAT-POS-590ac91e-57
0.370

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COc1ccccc1OCCC(=O)Nc1cc(=O)[nH]c2ccccc12

MAR-UCB-f313ec4d-1
0.367

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CC1(C)Cc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccc(Cl)cc34)c2O1

MAT-POS-590ac91e-53
0.366

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O=C(NCCOc1cc(Cl)cc(Oc2cccc(=O)[nH]2)c1)c1cc(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-19
0.364

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O=C(NCCOc1cc(Cl)cc(Oc2cccnc2)c1)c1cc(=O)[nH]c2ccccc12

ERI-UCB-ce40166b-20
0.360

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O=C1CC(Oc2cc(Cl)cc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ALP-POS-3fc1724e-2
0.358

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O=C1CC(Oc2cc(Cl)cc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-17
0.358

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COc1ccccc1OCC(CN1CCOCC1)NC(=O)c1cc(=O)[nH]c2ccccc12

DAR-DIA-8e329c92-8
0.357

View
O=C(NCCNc1ccccc1)c1cc(=O)[nH]c2ccccc12

BEN-DND-7e92b6ca-4
0.355

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N#Cc1ccccc1S(=O)(=O)N1CCN(C(=O)c2cc(=O)[nH]c3cc(F)ccc23)CC1

MAT-POS-590ac91e-61
0.349

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COc1ccccc1O[C@H]1CC[C@@H]1NC(=O)c1cc(=O)[nH]c2ccccc12

MAT-UCB-70f7c0f7-4
0.347

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Cn1c(=O)n(CCNC(=O)c2cc(=O)[nH]c3ccccc23)c2ccccc21

ADA-UCB-b1b30a00-1
0.343

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COc1ccccc1O[C@H]1CCCC[C@H]1NC(=O)c1cc(=O)[nH]c2ccccc12

ADA-UCB-b1b30a00-2
0.343

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CN(CCNC(=O)c1cc(=O)[nH]c2ccccc12)c1ccccc1

BEN-DND-7e92b6ca-3
0.337

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COc1cccc(NCNC(=O)c2cc(=O)[nH]c3ccccc23)c1

DAR-DIA-8e329c92-10
0.333

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N#Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4cc(F)ccc34)CC2)cc1

MAT-POS-590ac91e-60
0.330

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COc1ccccc1O[C@H]1CCC[C@@H]1NC(=O)c1cc(=O)[nH]c2ccccc12

MAT-UCB-70f7c0f7-3
0.330

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Cc1ccc(S(=O)(=O)N2CCN(C(=O)c3cc(=O)[nH]c4cc(F)ccc34)CC2)c(C)c1

MAT-POS-590ac91e-63
0.327

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O=C(NCCc1cccc2ccccc12)c1cc(=O)[nH]c2ccccc12

DAR-DIA-8e329c92-9
0.320

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COc1ccc(Cl)cc1OCCN(C)C(=O)c1cc(=O)[nH]c2ccccc12

BEN-DND-b89db3f2-5
0.318

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O=C(NCC1COc2ccccc2O1)c1cc(=O)[nH]c2ccc(F)cc12

MAT-POS-590ac91e-30
0.315

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COc1ccccc1OCCC(=O)Nc1cncc2ccccc12

MAR-UCB-f313ec4d-3
0.313

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COc1cccc2c1OCC(NC(=O)c1cc(=O)[nH]c3ccc(F)cc13)C2

MAT-POS-590ac91e-35
0.312

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COc1ccc(Cl)cc1OCCNC(=O)c1cc[nH]c(=O)c1

BEN-DND-b89db3f2-4
0.309

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COc1ccccc1OC1CN(C(=O)c2cc(=O)[nH]c3ccccc23)C1

ERI-UCB-a0b0dbcb-9
0.301

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NS(=O)(=O)c1ccc(CCNC(=O)c2cc(=O)[nH]c3ccccc23)c2ccccc12

DAR-DIA-8e329c92-11
0.299

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COc1ccccc1OC[C@H](C(=O)Nc1cc(=O)[nH]c2ccccc12)c1cccc(Cl)c1

ADA-UCB-6c2cb422-8
0.298

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NS(=O)(=O)c1ccc(CCNC(=O)c2cc(=O)[nH]c3ccccc23)c2c1CCCC2

DAR-DIA-8e329c92-12
0.295

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CCOc1ccccc1OC1CCN(C(=O)c2cc(=O)[nH]c3ccc(F)cc23)C1

MAT-POS-590ac91e-48
0.295

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CN(CC1COc2ccccc2O1)C(=O)c1cc(=O)[nH]c2ccc(F)cc12

MAT-POS-590ac91e-33
0.294

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COc1ccccc1N1CCN(C(=O)c2cc(=O)[nH]c3ccccc23)CC1

BEN-DND-7e92b6ca-13
0.288

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COc1ccc2c(C(=O)N(CCc3cccc(OC)c3OC)c3cccc(Cl)c3)cc(=O)[nH]c2c1

ALP-POS-19e898d3-1
0.288

View
COc1ccccc1OC1CCN(C(=O)c2cc(=O)[nH]c3ccccc23)C1

ERI-UCB-a0b0dbcb-6
0.284

View
CN1CCCc2c(S(N)(=O)=O)ccc(CCNC(=O)c3cc(=O)[nH]c4ccccc34)c21

DAR-DIA-8e329c92-13
0.283

View
O=C(c1cc(=O)[nH]c2ccccc12)N1CCN(c2cccc(F)c2)CC1

BEN-DND-7e92b6ca-15
0.276

View
COc1ccccc1NC1CN(C(=O)c2cc(=O)[nH]c3ccccc23)C1

ERI-UCB-a0b0dbcb-8
0.275

View
COc1ccccc1NC1CCN(C(=O)c2cc(=O)[nH]c3ccccc23)C1

ERI-UCB-a0b0dbcb-5
0.274

View
O=C(c1cc(=O)[nH]c2ccccc12)N1CCN(c2ccc(F)cc2)CC1

BEN-DND-7e92b6ca-14
0.265

View
COc1cc(C(=O)NCCc2nc(C)cc(=O)[nH]2)ccn1

MAR-TRE-c8530538-69
0.262

View
COc1ccc(Cl)cc1CC(=O)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-3b92565d-4
0.262

View
CN1CCN(c2ccc(NC(=O)c3cc(=O)[nH]c4ccccc34)cc2)CC1

KRI-MAR-d2e3ef86-15
0.262

View
COc1ccc(Cl)cc1CC(=O)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-e1b5ac6b-2
0.262

View
COC(=O)C(Cc1c[nH]c2cc(F)ccc12)NC(=O)c1cncnc1

MAR-TRE-799db12b-12
0.262

View
COc1cccc(CCN(C(=O)c2cc(=O)[nH]c3cc(OC)ccc23)c2cccc(Cl)c2)c1

ALP-POS-19e898d3-2
0.261

View
CSc1ncccc1C(=O)NCCc1nc(C)cc(=O)[nH]1

MAR-TRE-c8530538-39
0.260

View
COc1ccccc1OCC(O)CO

KEI-TRE-fa9ada3e-3
0.256

View
CC(=O)NCCc1c(O)[nH]c2ccc(F)cc12

SAN-PRS-3c4a6997-5
0.255

View
COc1ccccc1Cc1nc(CNC(=O)c2cncc(C)c2)cc(=O)[nH]1

MAR-TRE-c8530538-28
0.254

View
COc1ccccc1OC1CCCN(C(=O)c2cc(=O)[nH]c3ccc(Cl)cc23)C1

MAT-POS-590ac91e-54
0.254

View
COc1cc(Cl)cc(CN2CCN(C(=O)c3cc(=O)[nH]c4ccccc34)CC2)c1F

ALP-POS-3fc1724e-4
0.254

View
COc1ccc(N2CCN(C(=O)c3cc(=O)[nH]c4ccccc34)CC2)cc1

BEN-DND-7e92b6ca-11
0.252

View
COc1ccc(N2CCN(C(=O)c3cc(=O)[nH]c4ccccc34)CC2)cc1

KRI-MAR-d2e3ef86-13
0.252

View
COc1ccccc1OCCN1C(=O)C(=O)c2cc(Br)cc(C)c21

LOR-NOR-30067bb9-4
0.250

View
COc1ccnc(C(=O)NCCc2nc(C)cc(=O)[nH]2)c1

MAR-TRE-c8530538-52
0.250

View
O=C(O)c1c[nH]c2cc(F)ccc2c1=O

DEN-EUR-293438d2-1
0.250

View
O=C(COc1cccc(Cl)c1)N(C(=O)c1cc(=O)[nH]c2ccccc12)C1CC1

JAN-GHE-82a280f8-3
0.248

View
COc1cccc(N2CCN(C(=O)c3cc(=O)[nH]c4ccccc34)CC2)c1

MAR-UCB-f313ec4d-5
0.248

View
COc1cccc(N2CCN(C(=O)c3cc(=O)[nH]c4ccccc34)CC2)c1

BEN-DND-7e92b6ca-12
0.248

View
COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

1.000

View
COc1ccccc1OCCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.920

View
COc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.840

View
O=C(NCCOc1ccccc1Cl)c1cc(=O)[nH]c2cc(F)ccc12

0.804

View
Cc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.804

View
O=C(NCCOc1ccccc1F)c1cc(=O)[nH]c2cc(F)ccc12

0.800

View
COc1ccccc1OCCCNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.778

View
COc1ccccc1OCC(C)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.778

View
COc1ccccc1CCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.774

View
COc1ccccc1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.769

View
O=C(NCCOc1cccc2ccccc12)c1cc(=O)[nH]c2cc(F)ccc12

0.769

View
CC(C)c1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.759

View
CC(C)(C)c1ccccc1OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.759

View
Cc1ccccc1OCCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.745

View
O=C(NCCCOc1ccccc1F)c1cc(=O)[nH]c2cc(F)ccc12

0.741

View
O=C(NCCOc1ccccc1C(F)(F)F)c1cc(=O)[nH]c2cc(F)ccc12

0.741

View
O=C(NCCOc1cccc(Cl)c1Cl)c1cc(=O)[nH]c2cc(F)ccc12

0.741

View
O=C(NCCOc1ccccc1-c1ccccc1)c1cc(=O)[nH]c2cc(F)ccc12

0.741

View
COc1ccccc1OC(C)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.741

View
COc1ccccc1C(=O)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.736

View
COc1ccccc1OCCOC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.736

View
COCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.735

View
COc1ccc(OCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1

0.731

View
COc1cc(OC)cc(OCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1

0.731

View
COc1ccccc1OCC(=O)NNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.727

View
O=C(NCCOc1ccccc1)c1cc(=O)[nH]c2cc(F)ccc12

0.725

View
COc1ccccc1Oc1ccc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1

0.719

View
CCOc1cc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)ccc1OC

0.714

View
COc1ccccc1C(C)(C)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.714

View
COCCOc1ccccc1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.714

View
COc1cccc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1O

0.714

View
COc1ccc(CCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1OC

0.709

View
CCOc1cc(CCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)ccc1OC

0.707

View
COc1ccc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1OC

0.704

View
Cc1ccc(OCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c(C)c1

0.704

View
COc1cccc(CCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1OC

0.702

View
COc1ccc(CCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c2ccccc12

0.702

View
CCOc1ccc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1OC

0.702

View
COc1ccc2ccccc2c1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.702

View
COc1ccccc1OCCNC(=O)c1cc(F)ccc1OC

0.700

View
COCCCCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.698

View
COc1ccc(F)cc1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.698

View
COc1cccc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1OC

0.696

View
CCOc1ccccc1CCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.696

View
COc1cccc(Cl)c1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.696

View
COc1ccccc1OCCN(C)C(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.696

View
COc1cc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)ccc1OCc1ccccc1

0.695

View
COCCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.692

View
COc1ccccc1C(=O)NNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.692

View
COc1ccccc1NC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.692

View
CCOc1ccccc1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.691

View
COc1cccc(C(=O)NCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1

0.691

View
Cc1cccc(OCCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1C

0.690

View
O=C(NCCOc1ccc(F)cc1)c1cc(=O)[nH]c2cc(F)ccc12

0.686

View
COc1ccccc1OCCNC(=O)c1ccc(F)cc1F

0.686

View
COc1ccccc1OCCNC(=O)c1cc(F)ccc1F

0.686

View
COc1ccc(C(=O)NCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1

0.685

View
Cc1cccc(C)c1OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.685

View
COc1cc(OC)c(OC)cc1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.685

View
COc1cccc(OCCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1

0.684

View
COc1ccccc1C(O)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.684

View
COc1ccccc1C1(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)CC1

0.684

View
COCCCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.679

View
O=C(NCCOc1cccc(F)c1)c1cc(=O)[nH]c2cc(F)ccc12

0.679

View
COCCOCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.679

View
COCCNC(=O)c1ccccc1NC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.679

View
COCCOc1ccccc1NC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.679

View
COc1cc(OC)c(CCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c(OC)c1

0.679

View
COc1cc(OC)cc(OCCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1

0.679

View
COc1ccccc1OCCNC(=O)c1cc(C)nc2cc(F)ccc12

0.679

View
COc1ccc(OCCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1

0.679

View
COc1cccc2cc(CNC(=O)c3cc(=O)[nH]c4cc(F)ccc34)oc12

0.678

View
COc1cc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)ccc1OCCO

0.678

View
COc1ccccc1CCNC(=O)CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.678

View
COc1ccccc1OCCNC(=O)c1cc(F)ccc1Cl

0.673

View
COc1ccccc1OCCNC(=O)c1ccc(F)cc1Cl

0.673

View
COc1ccccc1OCCNC(=O)c1ccc(F)cc1C

0.673

View
COc1ccccc1OCCNC(=O)c1cc(F)ccc1C

0.673

View
CCOCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.673

View
COc1cc(OC)c(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c(OC)c1

0.673

View
Cc1ccccc1OCCNC(=O)c1cc(=O)[nH]c2ccc(F)cc12

0.673

View
COc1cc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc(OC)c1OC

0.673

View
O=C(NCCCOc1ccccc1)c1cc(=O)[nH]c2cc(F)ccc12

0.673

View
O=C(NCCOc1ccccc1Cl)c1cc(=O)[nH]c2ccc(F)cc12

0.673

View
COCOCCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.673

View
O=C(NCCOc1ccc2ccccc2c1)c1cc(=O)[nH]c2cc(F)ccc12

0.673

View
Cc1ccc(OCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1

0.667

View
O=C(NCCOc1ccccc1F)c1cc(=O)[nH]c2ccc(F)cc12

0.667

View
COc1ccc(CCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1F

0.667

View
CCOc1ccc(CCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1OCC

0.667

View
COCCOc1cc(NC(=O)c2cc(=O)[nH]c3cc(F)ccc23)ccc1OC

0.667

View
COc1cc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)ccc1OCCN(C)C

0.667

View
CC(C)COc1ccccc1CNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.667

View
O=C(NCCOCc1ccccc1)c1cc(=O)[nH]c2cc(F)ccc12

0.667

View
O=C(NCc1ccccc1OCCO)c1cc(=O)[nH]c2cc(F)ccc12

0.667

View
CCCCOc1ccc(CNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)cc1OC

0.667

View
Cc1cc(C)cc(OCCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)c1

0.667

View
COc1cc(CCNC(=O)c2cc(=O)[nH]c3cc(F)ccc23)ccc1F

0.667

View
CON(C)CCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.667

View
NC(=O)OCCNC(=O)c1cc(=O)[nH]c2cc(F)ccc12

0.667

View

C(NCCOC1=C(OC)C=CC=C1)(=O)C1C2C(=CC=CC=2)N=CC=1

0.858

View
C(NCCOC1=C(OC)C=CC=C1)(=O)C1C2C(=NC=CC=2)C=CC=1

0.834

View
C(NCCOC1=C(OC)C=CC=C1)(=O)C1=C2C(NC=C2)=CC=C1

0.814

View
C(N(CCOC1=C(OC)C=CC=C1)C)(=O)C1C2C(=CC=CC=2)N=CC=1

0.812

View
C(NCCOC1=C(OC)C=CC=C1)(=O)C1C2=C(C=CC=C2)N=C(OC)C=1

0.804

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