Molecule Details

Molecular Properties
SMILES:
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)cc1
MW: 299.779
Fraction sp3: 0.31
HBA: 3
HBD: 0
Rotatable Bonds: 3
TPSA: 54.45
cLogP: 1.87752
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-86119
Enamine SCR: Z1258919507
Enamine REAL: Z1258919507
Mcule: MCULE-5969876563
MolPort: MolPort-003-759-968

Activated double bonds (3)

Filter88_ene_sulfone

O=C(CCl)N(c1ccc(F)cc1)C1C=CS(=O)(=O)C1

AAR-POS-0daf6b7e-8
0.717

View
O=C(CCl)N(c1ccc(CO)cc1)C1C=CS(=O)(=O)C1

THO-SYG-98fc3427-2
0.704

View
O=C(CCl)N(c1ccccc1)C1C=CS(=O)(=O)C1

AAR-POS-0daf6b7e-1
0.679

View
O=C(CCl)N(c1ccc(CCO)cc1)C1C=CS(=O)(=O)C1

THO-SYG-98fc3427-1
0.667

View
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)cc1C

MAK-UNK-752736de-1
0.632

View
Cc1cccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)c1

MAK-UNK-7c9d1431-15
0.621

View
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)cc1Cc1ccsc1

THO-SYG-98fc3427-8
0.480

View
CC(=O)N(CCCC(=O)N(c1ccc(C)cc1)C1C=CS(=O)(=O)C1)c1cnccc1C

HAN-NEW-5f56c3bc-5
0.475

View
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)cc1CCc1ccsc1

THO-SYG-98fc3427-9
0.468

View
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)c(Cc2ccccc2)c1

SAL-INS-1c7a5a55-7
0.466

View
CC(=O)N(C(=O)N(c1ccc(C)cc1)C1C=CS(=O)(=O)C1)C1=CNCC=C1C

SEL-UNI-8426c22c-1
0.459

View
O=C(CCl)N(c1ccc(-c2ccc3oc4ccc5ccccc5c4c3c2)cc1)C1C=CS(=O)(=O)C1

MAK-UNK-c74072e5-5
0.459

View
O=C(CCl)N(c1ccc(CO)c(Cc2ccsc2)c1)C1C=CS(=O)(=O)C1

THO-SYG-98fc3427-10
0.455

View
O=C(CCl)N(c1ccc(-c2cccc3c2oc2ccc4ccccc4c23)cc1)C1C=CS(=O)(=O)C1

MAK-UNK-c74072e5-3
0.453

View
O=C(CCl)N(c1ccc(CO)c(CCc2ccsc2)c1)C1C=CS(=O)(=O)C1

THO-SYG-98fc3427-11
0.443

View
Cc1ccc(N(C(=O)CCl)C2C=NS(=O)(=O)C2)cc1C

MAK-UNK-942dcb71-2
0.433

View
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)c(Cc2c[nH]cn2)c1

SAL-INS-1c7a5a55-9
0.423

View
O=C(CCl)N1C=CC(N(C(=O)CCl)C2C=CS(=O)(=O)C2)=CC1

SEL-UNI-49ab05bd-2
0.414

View
CCNc1ncc(C#N)cc1Cc1cc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)ccc1C

THO-SYG-98fc3427-4
0.414

View
Cc1nccn1CC(=O)N(c1ccccc1)C1C=CS(=O)(=O)C1

JAN-GHE-4287bd1a-7
0.411

View
CCNc1ncc(C#N)cc1CCc1cc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)ccc1C

THO-SYG-98fc3427-5
0.404

View
O=C(CCn1ccnc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

JAN-GHE-4287bd1a-8
0.400

View
O=C(CCl)N(c1ccc(F)cc1Cc1ccccc1)C1C=CS(=O)(=O)C1

SAL-INS-1c7a5a55-8
0.397

View
CCNc1ncc(C#N)cc1Cc1cc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)ccc1CO

THO-SYG-98fc3427-7
0.396

View
CCNc1ncc(C#N)cc1CCc1cc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)ccc1CO

THO-SYG-98fc3427-6
0.391

View
CS(=O)(=O)Nc1cccc(C(=O)CC(=O)N(c2ccc(F)cc2)C2C=CS(=O)(=O)C2)c1

JAR-IMP-ed466bb3-18
0.372

View
O=C(CCl)N(c1ccc(F)cc1Cc1c[nH]cn1)C1C=CS(=O)(=O)C1

SAL-INS-1c7a5a55-10
0.361

View
Cc1ccc(N(C(=O)CCl)C2CS(=O)(=O)C=N2)cc1C

MAK-UNK-942dcb71-1
0.357

View
O=C(CCl)N1CCC(C(=O)N(CC(=O)N(c2ccccc2)[C@H]2C=CS(=O)(=O)C2)c2ccc3ccccc3c2)CC1

SAD-SAT-9a6c5cf3-8
0.337

View
CC(=O)N1CCN(C(C(=O)N(c2ccc(F)cc2)C2C=CS(=O)(=O)C2)c2ccsc2)CC1

MAK-UNK-902cc841-6
0.333

View
N#Cc1ccc([S+]([O-])c2c(N(C(=O)CCl)C3C=CS(=O)(=O)C3)nn(C3CC(O)C3)c2N)cn1

FAB-NA_-a0010840-1
0.330

View
CC(=O)N1CCN(C(C(=O)N(c2ccc(F)cc2)C2C=CS(=O)(=O)C2)c2cccs2)CC1

MAK-UNK-902cc841-5
0.322

View
C=CC(=O)N(Cc1ccccc1)C1C=CS(=O)(=O)C1

SAD-SAT-f0a2747f-3
0.310

View
Cc1c(N)cncc1NC(=O)CC(c1ccsc1)C1C=C(N(C(=O)CCl)C2C=CS(=O)(=O)C2)C=CN1C(=O)CCl

SEL-UNI-49ab05bd-3
0.304

View
Cc1ccc(N(C(=O)C(=O)[C@H](C[C@@H]2CCNC2=O)NC(=O)[C@H](CC(C)C)NS(=O)(=O)NCc2ccccc2)C2C=CS(=O)(=O)C2)cc1

YUN-WES-58b0dbae-4
0.304

View
Cc1ccc(N(C(=O)C(=O)[C@H](C[C@@H]2CCNC2=O)NC(=O)[C@H](CC2CC2)NC(=O)c2cc3ccccc3[nH]2)[C@H]2C=CS(=O)(=O)C2)cc1

DAV-SYG-f22c749d-7
0.302

View
O=C(CCl)N(c1cccnc1)C1CCS(=O)(=O)C1

DAN-PUR-3907f623-3
0.301

View
N#Cc1ccc(Cc2c(N(C(=O)CCl)C3C=CS(=O)(=O)C3)nn(C3=CCCCO3)c2Cl)cn1

FAB-NA_-a0010840-3
0.301

View
Cc1ccc(N(C(=O)C(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CC2CC2)NC(=O)c2cc3ccccc3[nH]2)[C@H]2C=CS(=O)(=O)C2)cc1

DAV-SYG-f22c749d-8
0.292

View
Cc1cccc(NC2C=CS(=O)(=O)C2)c1

MAK-UNK-752736de-6
0.279

View
N#Cc1ccc(Oc2cc3c(nc2N(C(=O)CCl)C2C=CS(=O)(=O)C2)CNCN3c2ncc(O)o2)cn1

FAB-NA_-a0010840-2
0.277

View
CN(C(=O)CCl)c1ccccc1

SAD-SAT-d8079f6f-8
0.271

View
CCN(C(=O)CCl)c1ccccc1

SAD-SAT-d8079f6f-7
0.262

View
Cc1ccc(S(=O)(=O)NC(=O)CCl)cc1

MAR-TRE-6a44bbf2-48
0.254

View
Cc1ccc(S(=O)(=O)NC(=O)CCl)cc1

SAD-SAT-65574d3f-4
0.254

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AHN-SAT-de2502ba-8
0.250

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-25
0.250

View
Cc1ccc2cc(-c3[nH]ccc3C(=O)c3ccc(C)c(Cl)c3)cc(N(C(=O)CCl)[C@H]3CCS(=O)(=O)C3)c2c1

INS-INS-8dbfb37c-1
0.248

View
Cc1ccc(C(=O)N2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-3f402c2b-4
0.247

View
O=S1(=O)C=CC(c2ccccc2)C1

MAK-UNK-752736de-8
0.246

View
Cc1ccc(CN2CCCN(C(=O)CCl)CC2)cc1

MAK-UNK-7c9d1431-21
0.240

View
CS(=O)(=O)CCN(C(=O)CCl)c1ccc(CO)cc1

THO-SYG-98fc3427-3
0.239

View
O=S1(=O)C=CC(NCc2ccccc2)C1

MAK-UNK-752736de-12
0.239

View
CC(C)N(C(=O)CCl)c1ccccc1

SAD-SAT-d8079f6f-10
0.238

View
NCN(C(=O)CCl)c1ccc(F)cc1

MAK-UNK-e0fdfe28-1
0.238

View
Cc1ccc(C(c2cccc(C)c2)N2CCN(C(=O)CCl)CC2)cc1

MED-COV-4280ac29-23
0.237

View
Cc1ccc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)cc1

NIM-UNI-05f93fcc-11
0.237

View
Nc1cncc(NC(=O)c2ccc(N3CCC(CN(C(=O)CCl)C4C=CS(=O)(=O)C4)OCN3C(=O)CCl)cn2)c1

SEL-UNI-49ab05bd-1
0.237

View
Cc1ccc(S(=O)(=O)NC2CCN(C(=O)CCl)CC2)cc1

WAR-XCH-79d12f6e-4
0.237

View
O=C(CC1C=CS(=O)(=O)C1)NCc1ccccc1Cl

MAK-UNK-752736de-4
0.237

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-d2a4d1df-27
0.236

View
Cc1ccc(S(=O)(=O)N2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-68
0.236

View
Cc1ccc(S(=O)(=O)N2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-3f402c2b-5
0.234

View
Cc1ccc(C(c2ccccc2)N2CCN(C(=O)CCl)CC2)cc1

GIA-UNK-7337c2f3-7
0.234

View
Cc1ccc(N(C(=O)[C@H]2N3C(=O)C[C@@H]3S(=O)(=O)C2(C)C)[C@@H](C(=O)NC2CCCCC2)c2ccc(O)cc2)cc1

FAR-UNI-9564ba6c-1
0.233

View
Cc1ccc(N(C(=O)C2N3C(=O)CC3S(=O)(=O)C2(C)C)C(C(=O)NC2CCCCC2)c2ccc(O)cc2)cc1

AAR-POS-fca48359-11
0.233

View
Cc1ccc(C(c2cccc(C)c2)N2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-ec98eaf6-9
0.233

View
O=S1(=O)C=CC(Nc2ccccc2)C1

MAK-UNK-752736de-10
0.231

View
Cc1ccc(NC(=O)CN2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-12
0.227

View
O=S1(=O)C=CC(Nc2cccc(Cl)c2)C1

MAK-UNK-752736de-3
0.225

View
Cc1ccc(CCCNC(=O)CC(O)O)cc1

NEL-UNI-1464a899-2
0.225

View
CN(C[C@@H]1COc2ccccc2O1)C(=O)CCl

MAR-TRE-6a44bbf2-80
0.224

View
CN(C)c1ccc(C(CNC(=O)C2CCN(C(=O)CCl)CC2)N(C)C)cc1

SAD-SAT-29425be4-19
0.224

View
Cc1cccc(N(c2cccc(N)c2)C2CCN(C(=O)CCl)CC2)c1

MED-COV-4280ac29-4
0.224

View
Cc1ccc(CCCNC(=O)CC(C)O)cc1

NEL-UNI-1464a899-7
0.222

View
Cc1ccc(N(C)C2CCN(c3ccc(S(N)(=O)=O)cc3)CC2)cc1

WAR-XCH-b6889685-56
0.221

View
CC(=O)N(C(=O)CCl)c1cncc(N)c1

DAN-PUR-19f24f0c-2
0.221

View
CCCC1CCC(Oc2ccc(C)cc2)CC1

MAK-UNK-5e88aa6a-2
0.221

View
Cc1ccc(S(=O)(=O)NC2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-df1a028e-5
0.220

View
Cc1ccc(N(C)CC2CCN(c3ccc(S(N)(=O)=O)cc3)CC2)cc1

WAR-XCH-b6889685-4
0.220

View
O=C(Nc1ccccc1)NN(C(=O)CCl)c1ccccc1

TAT-ENA-80bfd3e5-23
0.219

View
Cc1cccc(NC2CCN(C(=O)CCl)CC2)c1

NIR-THE-0d6461ce-1
0.218

View
Cc1ccc(C(=O)N2CCN(C(=O)CCl)C(CC(=N)N)C2)cc1

SEL-UNI-cd366922-1
0.217

View
Cc1ccc(C2=NN(C(=O)CCl)C(c3ccco3)C2)cc1

NIM-UNI-13494739-2
0.217

View
Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.216

View
Cc1ccc(NC(=O)C2CCN(C(=O)CCl)CC2)nc1

MAK-UNK-c97f7c8f-1
0.215

View
Cc1ccc(CCC(c2cccc(Cl)c2)N2CCN(C(=O)CCl)CC2)cc1

PAU-WEI-b9b69149-3
0.213

View
Cc1ccc(CCC(c2cccc(Cl)c2)N2CC3CC2CN3C(=O)CCl)cc1

MAK-UNK-ec98eaf6-50
0.213

View
Cc1cccc(C(C)(C)CNC(=O)C2CCN(C(=O)CCl)CC2)c1

SAD-SAT-29425be4-20
0.212

View
Cc1cc(C)cc(-c2ccc(S(=O)(=O)N3CCN(C(=O)CCl)CC3)s2)c1

NIM-UNI-05f93fcc-7
0.212

View
Cc1cccc(NC2C=NS(=O)(=O)C2)c1

MAK-UNK-942dcb71-11
0.211

View
Cc1ccc(S(=O)(=O)N2CCCN(C(=O)C3CCN(C(=O)CCl)CC3)CC2)cc1

SAD-SAT-9a6c5cf3-2
0.211

View
CCN(Cc1ccc2c(c1)OCCO2)C(=O)CCl

MAR-TRE-6a44bbf2-50
0.211

View
CN(C(=O)CCl)C1CCCCC1

SAD-SAT-d8079f6f-9
0.210

View
Cc1cccc(N(c2ccc(Cl)s2)C2CCN(C(=O)CCl)CC2)c1

NIR-THE-0d6461ce-11
0.209

View
O=C(CC1C=CS(=O)(=O)C1)NC1CCOc2ccccc21

MAK-UNK-752736de-5
0.209

View
CN(C(=O)CCl)c1cc(N(C)C(=O)CCl)nc(C#N)n1

MAK-UNK-72659d64-14
0.209

View
CN(C(=O)CCl)c1cnc(C#N)nc1

MAK-UNK-72659d64-7
0.209

View
Cc1cccc(NC2CS(=O)(=O)C=N2)c1

MAK-UNK-942dcb71-12
0.208

View
N=C(N)CCN(C(=O)CCl)C1CCS(=O)(=O)C1

DAN-PUR-6788a628-1
0.208

View
CC1=CC=C(SCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.537

View
CC1=CC=C(N(C)CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.529

View
CC1=CC=C(C(C)NCC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.521

View
CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.516

View
CC1=CC=C(SCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.515

View
CC1=CC=C(N(C(=O)CCl)C2CCC2)C=C1

0.509

View
CC1=CC=C(SCC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.507

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.500

View
CC1=CC=C(N(CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C(C)C)C=C1

0.500

View
CS(=O)(=O)CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.500

View
CCC(NCC(=O)N(C1=CC=C(C)C(C)=C1)C1C=CS(=O)(=O)C1)C1=CC=C(C)C=C1

0.500

View
CC(=O)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.500

View
CC(Cl)(Cl)C(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.500

View
CC1=CC=C(C(C)(C)C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.493

View
CCS(=O)(=O)CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.492

View
CC1=CC=C(C)C(SCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=C1

0.486

View
CC(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.485

View
CC1=CC=C(CC(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.480

View
CC1=CC=C(C(C)C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.480

View
CC1=CC=C(C)C(N(C)CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)=C1

0.479

View
CSCC(=O)N(C1=CC=CC=C1)C1C=CS(=O)(=O)C1

0.476

View
CC1=CC=C(C(C)N(C)CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.474

View
CC1=CC=C(CN(C)CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.473

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.472

View
CSCC(=O)N(C1=CC=C(C)C(C)=C1)C1C=CS(=O)(=O)C1

0.470

View
CC1=CC=C(N(C(=O)CC2C=CS(=O)(=O)C2)C2CCC2)C=C1

0.470

View
CC1=CC=C(OCC(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.468

View
CC1=CC=C(C=CC(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.468

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.467

View
CC1=CC=C(C(C)C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.467

View
CC1=CC=C(C(C)(C)C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.467

View
CC1=CC=C(SCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C(C)=C1

0.466

View
CCC(CC)SCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.464

View
CC1=CC=C(N(C(=O)CS(C)(=O)=O)C2C=CS(=O)(=O)C2)C=C1C

0.463

View
O=C(CSC1=CC=C(F)C=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.463

View
CC(=O)CSCC(=O)N(C1=CC=CC=C1)C1C=CS(=O)(=O)C1

0.463

View
CC1=CC=C(C2=NN(CC(=O)N(C3=CC=C(F)C=C3)C3C=CS(=O)(=O)C3)N=N2)C=C1

0.462

View
CC1=CC=C(CC(C)C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.462

View
CC1=CC=C(OC(C)C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.462

View
CC1=CC=C(C(F)(F)C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.461

View
CC1=CC=C(C)C(SCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)=C1

0.459

View
CC1=CC=C(SCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)N=C1

0.459

View
CCN(CC)CC(=O)N(C1=CC=C(C)C(C)=C1)C1C=CS(=O)(=O)C1

0.456

View
CC1=CC=C(C)C(CSCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=C1

0.455

View
CCN(CC(=O)N(C1=CC=C(C)C(C)=C1)C1C=CS(=O)(=O)C1)CC1=CC=C(C)C=C1

0.455

View
CC1=CC=C(CN(CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C2CC2)C=C1

0.455

View
CC(=O)OCC(=O)N(C1=CC=CC=C1)C1C=CS(=O)(=O)C1

0.455

View
CC1=CC=C(CC(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.453

View
CC1=CC=C(C)C(SCC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)=C1

0.453

View
CC1=CC=C(OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)N=C1

0.453

View
CC1=CN=C(SCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)N=C1

0.452

View
CC1=CC=C(C=CCC(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.450

View
CC1=CC=C(N(C)CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1C

0.449

View
CC1=CC=C(Cl)C(OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=C1

0.449

View
CC1=CC=C(CC(=O)OCC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.449

View
CC1=CC=C(CC(C)C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.449

View
CC1=CC=C(C)C(C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=C1

0.449

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)N=C1

0.447

View
CC1=CC=C(SCC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C(C)=C1

0.447

View
CC1=NC(Cl)=NN1CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.446

View
CC1=CC=C(SCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C(C)=C1

0.446

View
CC1=NN(CC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C(Cl)=N1

0.446

View
CC1=CC=C(OCCC(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.444

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C(Cl)=C1

0.443

View
CCC(=CC(=O)OCC(=O)N(C1=CC=CC=C1)C1C=CS(=O)(=O)C1)C1=CC=C(C)C=C1

0.443

View
CC1=CC=C(OCC(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.442

View
CC1=CC=C(F)C(OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=C1

0.442

View
CC1=CC=C(C2=NN(CC(=O)N(C3=CC=CC=C3)C3C=CS(=O)(=O)C3)N=N2)C=C1

0.442

View
CC1=CC=C(SCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)N=C1

0.440

View
CC1=CC(C)=CC(CSCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=C1

0.440

View
CC1=CC=C(N(C)CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C(C)=C1

0.440

View
CC1=CC(C)=CC(N(C)CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)=C1

0.438

View
CC1=CC=C(OCC(=O)OCC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.438

View
CC1=CC=C(F)C(C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=C1

0.436

View
CC1=CC=C(C=CC(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.436

View
CC1=CC=C(OC(C)C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.436

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C(F)=C1

0.436

View
CC1=CC(C)=CC(C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=C1

0.434

View
CC1=CN=C(SCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)N=C1

0.432

View
O=C(COC1=CC=C(Cl)C=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.432

View
CC1=CC=C(OCCN(C)CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.432

View
CC1=CC=C(C2=NN=C(SCC(=O)N(C3=CC=CC=C3)C3C=CS(=O)(=O)C3)[NH]2)C=C1

0.432

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C(C)=C1

0.430

View
CC1=CC=C(CC2=NN(CC(=O)N(C3=CC=C(F)C=C3)C3C=CS(=O)(=O)C3)N=N2)C=C1

0.429

View
CC1=CC=C(C2CCCN2CC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)C=C1

0.427

View
CC1=CC=C(C(=O)CCC(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.425

View
CC1=CC=C(Cl)C(OCC(=O)N(C2=CC=C(C)C(C)=C2)C2C=CS(=O)(=O)C2)=C1

0.425

View
CC1=CC=CC=C1SCC(=O)N(C1=CC=CC=C1)C1C=CS(=O)(=O)C1

0.425

View
CC1=CC=C(N2N=NN=C2SCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.422

View
CC1=CC=C(OCCC(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.420

View
CC1=CC=C(N(C(=O)CN2CCN(CC(=O)N(C)C)CC2)C2C=CS(=O)(=O)C2)C=C1C

0.419

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C(Cl)=C1

0.418

View
CC1=CC=C(N(C(=O)COC2=CC=C(Cl)C=C2)C2C=CS(=O)(=O)C2)C=C1C

0.416

View
CC1=CC(C)=CC(C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)=C1

0.413

View
CC1=CC(C)=C(CC(=O)OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C(C)=C1

0.412

View
CC1=CC=C(C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)N=C1

0.410

View
CC1=CC=C(OCCCC(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.410

View
CC1=CC(C)=CC(CSCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)=C1

0.408

View
CC1=CC=C(C(=O)C2=CC=CC=C2C(=O)OCC(=O)N(C2=CC=CC=C2)C2C=CS(=O)(=O)C2)C=C1

0.405

View
CC1=CC=C(N2C(SCC(=O)N(C3=CC=CC=C3)C3C=CS(=O)(=O)C3)=NC3=CC=CC=C32)C=C1

0.389

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:14|

1.000

View
CCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1 |c:10|

0.745

View
Fc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:14|

0.717

View
COc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:15|

0.709

View
CCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1 |c:11|

0.704

View
COCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1 |c:11|

0.691

View
CC(C)CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1 |c:12|

0.691

View
CCOc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:16|

0.684

View
ClCC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:10|

0.679

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1 |c:9|

0.667

View
CCCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1 |c:12|

0.667

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(Cl)(Cl)Cl |c:14|

0.636

View
Cc1ccc(cc1C)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:15|

0.632

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1 |c:11|

0.630

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)Cc1ccccc1 |c:14|

0.623

View
Cc1cccc(c1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:14|

0.621

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(C)(C)C |c:14|

0.618

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCc1ccccc1 |c:14|

0.613

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(F)(F)F |c:14|

0.607

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)COc1ccccc1 |c:14|

0.603

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)c1ccc(C)cc1 |c:14|

0.589

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C1CC1 |c:14|

0.579

View
CCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(Cl)cc1 |c:10|

0.569

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CNc1ccccc1C |c:14|

0.567

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)c1ccccc1 |c:14|

0.550

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C1CCCC1 |c:14|

0.541

View
CC(C)CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(cc1)C(C)C |c:12|

0.516

View
Cc1ccc(cc1C)N(C1CS(=O)(=O)C=C1)C(=O)CCCl |c:15|

0.516

View
CCc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(C)=O |c:15|

0.508

View
CCC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:10|

0.508

View
CCc1ccccc1N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:15|

0.508

View
CCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(cc1)C(C)C |c:11|

0.508

View
CCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(Cl)c1 |c:10|

0.508

View
COCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(cc1)C(C)C |c:11|

0.500

View
CCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(C)c1 |c:10|

0.500

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(Cl)cc1 |c:9|

0.500

View
CCCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(cc1)C(C)C |c:12|

0.485

View
CCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(Cl)c1 |c:11|

0.485

View
CCc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(C)C |c:15|

0.484

View
CCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:11|

0.484

View
CC(C)c1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(C)=O |c:16|

0.483

View
CCC(=O)N(C1CS(=O)(=O)C=C1)c1cc(C)cc(C)c1 |c:10|

0.483

View
COCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(Cl)c1 |c:11|

0.478

View
CCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(C)c1 |c:11|

0.477

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(cc1)C(C)C |c:11|

0.475

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:9|

0.475

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(Br)cc1 |c:9|

0.475

View
CCc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(F)(F)F |c:15|

0.469

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:9|

0.466

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(Cl)c1 |c:9|

0.460

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(C)c1 |c:9|

0.459

View
CC(C)c1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)Cc1ccccc1 |c:16|

0.457

View
CCC(CC)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(cc1)C(C)C |c:13|

0.455

View
CC(C)c1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(C)(C)C |c:16|

0.453

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc(C)c1 |c:9|

0.452

View
COc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(Cl)(Cl)Cl |c:15|

0.446

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1cc(C)cc(C)c1 |c:9|

0.441

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(Cl)c1 |c:11|

0.433

View
Cc1ccc(cc1Cl)N(C1CS(=O)(=O)C=C1)C(=O)C(C)(C)C |c:15|

0.433

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)c(C)c1 |c:11|

0.431

View
Cc1ccc(cc1C)N(C1CS(=O)(=O)C=C1)C(=O)C(C)(C)C |c:15|

0.431

View
Cc1ccc(cc1C)N(C1CS(=O)(=O)C=C1)C(=O)C(F)(F)F |c:15|

0.431

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1C |c:9|

0.429

View
Cc1ccc(cc1Cl)N(C1CS(=O)(=O)C=C1)C(=O)C(F)(F)F |c:15|

0.426

View
Cc1ccc(cc1Cl)N(C1CS(=O)(=O)C=C1)C(=O)C1CC1 |c:15|

0.426

View
CC(C)c1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C1CC1 |c:16|

0.424

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1cccc(C)c1 |c:11|

0.424

View
CC(Cl)C(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:11|

0.422

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:11|

0.419

View
CCc1ccccc1N(C1CS(=O)(=O)C=C1)C(C)=O |c:15|

0.415

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc(Cl)c1 |c:9|

0.415

View
FC(F)(F)C(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:12|

0.413

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1cc(C)cc(C)c1 |c:11|

0.413

View
Cc1cc(C)cc(c1)N(C1CS(=O)(=O)C=C1)C(=O)C(C)(C)C |c:15|

0.413

View
Cc1cc(C)cc(c1)N(C1CS(=O)(=O)C=C1)C(=O)C(F)(F)F |c:15|

0.406

View
COC(=O)c1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(F)(F)F |c:17|

0.406

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1C |c:11|

0.403

View
Cc1ccc(N(C2CS(=O)(=O)C=C2)C(=O)C(F)(F)F)c(C)c1 |c:11|

0.403

View
Cc1cccc(c1)N(C1CS(=O)(=O)C=C1)C(=O)C(F)(F)F |c:14|

0.403

View
Cc1ccc(cc1C)N(C1CS(=O)(=O)C=C1)C(=O)C1CC1 |c:15|

0.403

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc(c1)C(F)(F)F |c:9|

0.397

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1C |c:9|

0.397

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CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc(Br)c1 |c:9|

0.394

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CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc(C)c1C |c:9|

0.379

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1C |c:11|

0.373

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CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc2ccccc12 |c:9|

0.371

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Cc1c(Cl)cccc1N(C1CS(=O)(=O)C=C1)C(=O)C(Cl)(Cl)Cl |c:15|

0.366

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FC(F)(F)c1cccc(c1)N(C1CS(=O)(=O)C=C1)C(=O)C(Cl)(Cl)Cl |c:17|

0.356

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C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(C(Cl)Cl)=O

0.949

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C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)C

0.937

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C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CC

0.895

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C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CSC

0.893

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C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CSCC

0.878

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Discussion: