Molecule Details

Molecular Properties
SMILES:
O=C(CCl)N(c1ccc(F)cc1)C1C=CS(=O)(=O)C1
MW: 303.742
Fraction sp3: 0.25
HBA: 3
HBD: 0
Rotatable Bonds: 3
TPSA: 54.45
cLogP: 1.7082
Covalent Warhead: ✔️
Covalent Fragment:
Source
Enamine BB: EN300-86123
Enamine SCR: Z1258919512
Mcule: MCULE-9453295323
MolPort: MolPort-003-759-970

Activated double bonds (3)

Filter88_ene_sulfone

Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)cc1

AAR-POS-0daf6b7e-7
0.717

View
O=C(CCl)N(c1ccc(CO)cc1)C1C=CS(=O)(=O)C1

THO-SYG-98fc3427-2
0.691

View
O=C(CCl)N(c1ccccc1)C1C=CS(=O)(=O)C1

AAR-POS-0daf6b7e-1
0.667

View
O=C(CCl)N(c1ccc(CCO)cc1)C1C=CS(=O)(=O)C1

THO-SYG-98fc3427-1
0.655

View
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)cc1C

MAK-UNK-752736de-1
0.593

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Cc1cccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)c1

MAK-UNK-7c9d1431-15
0.557

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CS(=O)(=O)Nc1cccc(C(=O)CC(=O)N(c2ccc(F)cc2)C2C=CS(=O)(=O)C2)c1

JAR-IMP-ed466bb3-18
0.487

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Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)cc1Cc1ccsc1

THO-SYG-98fc3427-8
0.474

View
O=C(CCl)N(c1ccc(CO)c(Cc2ccsc2)c1)C1C=CS(=O)(=O)C1

THO-SYG-98fc3427-10
0.449

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O=C(CCl)N(c1ccc(F)cc1Cc1ccccc1)C1C=CS(=O)(=O)C1

SAL-INS-1c7a5a55-8
0.447

View
CC(=O)N1CCN(C(C(=O)N(c2ccc(F)cc2)C2C=CS(=O)(=O)C2)c2ccsc2)CC1

MAK-UNK-902cc841-6
0.444

View
O=C(CCl)N(c1ccc(F)cc1Cc1c[nH]cn1)C1C=CS(=O)(=O)C1

SAL-INS-1c7a5a55-10
0.443

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Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)cc1CCc1ccsc1

THO-SYG-98fc3427-9
0.443

View
O=C(CCl)N(c1ccc(CO)c(CCc2ccsc2)c1)C1C=CS(=O)(=O)C1

THO-SYG-98fc3427-11
0.438

View
O=C(CCl)N(c1ccc(-c2ccc3oc4ccc5ccccc5c4c3c2)cc1)C1C=CS(=O)(=O)C1

MAK-UNK-c74072e5-5
0.437

View
CC(=O)N1CCN(C(C(=O)N(c2ccc(F)cc2)C2C=CS(=O)(=O)C2)c2cccs2)CC1

MAK-UNK-902cc841-5
0.432

View
O=C(CCl)N(c1ccc(-c2cccc3c2oc2ccc4ccccc4c23)cc1)C1C=CS(=O)(=O)C1

MAK-UNK-c74072e5-3
0.432

View
O=C(CCl)N1C=CC(N(C(=O)CCl)C2C=CS(=O)(=O)C2)=CC1

SEL-UNI-49ab05bd-2
0.408

View
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)c(Cc2ccccc2)c1

SAL-INS-1c7a5a55-7
0.403

View
Cc1ccc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)c(Cc2c[nH]cn2)c1

SAL-INS-1c7a5a55-9
0.400

View
CCNc1ncc(C#N)cc1Cc1cc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)ccc1C

THO-SYG-98fc3427-4
0.393

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Cc1nccn1CC(=O)N(c1ccccc1)C1C=CS(=O)(=O)C1

JAN-GHE-4287bd1a-7
0.387

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NCN(C(=O)CCl)c1ccc(F)cc1

MAK-UNK-e0fdfe28-1
0.386

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Cc1ccc(N(C(=O)CCl)C2C=NS(=O)(=O)C2)cc1C

MAK-UNK-942dcb71-2
0.386

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CCNc1ncc(C#N)cc1CCc1cc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)ccc1C

THO-SYG-98fc3427-5
0.385

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O=C(CCn1ccnc1)N(c1ccccc1)C1C=CS(=O)(=O)C1

JAN-GHE-4287bd1a-8
0.377

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CCNc1ncc(C#N)cc1Cc1cc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)ccc1CO

THO-SYG-98fc3427-7
0.376

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CCNc1ncc(C#N)cc1CCc1cc(N(C(=O)CCl)C2C=CS(=O)(=O)C2)ccc1CO

THO-SYG-98fc3427-6
0.372

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CC(=O)N(CCCC(=O)N(c1ccc(C)cc1)C1C=CS(=O)(=O)C1)c1cnccc1C

HAN-NEW-5f56c3bc-5
0.368

View
CC(=O)N(C(=O)N(c1ccc(C)cc1)C1C=CS(=O)(=O)C1)C1=CNCC=C1C

SEL-UNI-8426c22c-1
0.346

View
N#Cc1ccc([S+]([O-])c2c(N(C(=O)CCl)C3C=CS(=O)(=O)C3)nn(C3CC(O)C3)c2N)cn1

FAB-NA_-a0010840-1
0.340

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Cc1ccc(N(C(=O)CCl)C2CS(=O)(=O)C=N2)cc1C

MAK-UNK-942dcb71-1
0.333

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O=C(CCl)N1CCC(C(=O)N(CC(=O)N(c2ccccc2)[C@H]2C=CS(=O)(=O)C2)c2ccc3ccccc3c2)CC1

SAD-SAT-9a6c5cf3-8
0.333

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C=CC(=O)N(Cc1ccccc1)C1C=CS(=O)(=O)C1

SAD-SAT-f0a2747f-3
0.306

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N#Cc1ccc(Cc2c(N(C(=O)CCl)C3C=CS(=O)(=O)C3)nn(C3=CCCCO3)c2Cl)cn1

FAB-NA_-a0010840-3
0.298

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N#Cc1ccc(Oc2cc3c(nc2N(C(=O)CCl)C2C=CS(=O)(=O)C2)CNCN3c2ncc(O)o2)cn1

FAB-NA_-a0010840-2
0.286

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O=C(CCl)N(c1cccnc1)C1CCS(=O)(=O)C1

DAN-PUR-3907f623-3
0.280

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Cc1c(N)cncc1NC(=O)CC(c1ccsc1)C1C=C(N(C(=O)CCl)C2C=CS(=O)(=O)C2)C=CN1C(=O)CCl

SEL-UNI-49ab05bd-3
0.278

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CN(CC(=O)Nc1ccc(F)cc1)C(=O)CCl

MAR-TRE-6a44bbf2-85
0.275

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C[C@H](NC(=O)CNC(=O)CCl)c1ccc(F)cc1

MAR-TRE-6a44bbf2-81
0.271

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O=C(CCl)N1CCO[C@@H](c2ccc(F)cc2)C1

MAR-TRE-6a44bbf2-39
0.253

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O=C(CCl)N1CCOC(c2ccc(F)cc2)C1

AAR-POS-d2a4d1df-33
0.253

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O=C(Nc1ccccc1)NN(C(=O)CCl)c1ccccc1

TAT-ENA-80bfd3e5-23
0.250

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O=C(CC1C=CS(=O)(=O)C1)NCc1cccc(F)c1

MAK-UNK-752736de-2
0.250

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O=C(CCl)N1CCN(C(c2ccccc2)c2ccc(F)cc2)CC1

GIA-UNK-7337c2f3-4
0.247

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CN(C(=O)CCl)c1ccccc1

SAD-SAT-d8079f6f-8
0.246

View
Cc1ccc(N(C(=O)C(=O)[C@H](C[C@@H]2CCNC2=O)NC(=O)[C@H](CC(C)C)NS(=O)(=O)NCc2ccccc2)C2C=CS(=O)(=O)C2)cc1

YUN-WES-58b0dbae-4
0.246

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Nc1cncc(NC(=O)c2ccc(N3CCC(CN(C(=O)CCl)C4C=CS(=O)(=O)C4)OCN3C(=O)CCl)cn2)c1

SEL-UNI-49ab05bd-1
0.246

View
N#CCCN(C(=O)CN1CCCCC(=O)C1=O)c1ccc(F)cc1

JAN-GHE-4287bd1a-6
0.244

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O=S1(=O)C=CC(c2ccccc2)C1

MAK-UNK-752736de-8
0.242

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Cc1cccc(NC2C=CS(=O)(=O)C2)c1

MAK-UNK-752736de-6
0.239

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CCN(C(=O)CCl)c1ccccc1

SAD-SAT-d8079f6f-7
0.238

View
Cc1ccc(N(C(=O)C(=O)[C@H](C[C@@H]2CCNC2=O)NC(=O)[C@H](CC2CC2)NC(=O)c2cc3ccccc3[nH]2)[C@H]2C=CS(=O)(=O)C2)cc1

DAV-SYG-f22c749d-7
0.236

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O=C(CC1C=CS(=O)(=O)C1)NCc1ccccc1Cl

MAK-UNK-752736de-4
0.234

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O=C(CCl)N1CC2CC1C(c1ccc(F)cc1)O2

MAK-UNK-3f402c2b-10
0.234

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

KAY-MCD-d0fe5261-1
0.233

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

MAR-TRE-6a44bbf2-58
0.233

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O=C(NCCc1c[nH]c2ccc(F)cc12)NCC1CCCCC1

FRA-LAB-04e32718-1
0.231

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Cc1ccc(N(C(=O)C(=O)[C@H](Cc2cccnc2)NC(=O)[C@H](CC2CC2)NC(=O)c2cc3ccccc3[nH]2)[C@H]2C=CS(=O)(=O)C2)cc1

DAV-SYG-f22c749d-8
0.228

View
O=S1(=O)C=CC(Nc2ccccc2)C1

MAK-UNK-752736de-10
0.227

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O=C(CCl)Nc1ccc(S(=O)(=O)c2ccc(F)cc2)cc1

MAR-TRE-6a44bbf2-90
0.225

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Cc1ccc2cc(-c3[nH]ccc3C(=O)c3ccc(C)c(Cl)c3)cc(N(C(=O)CCl)[C@H]3CCS(=O)(=O)C3)c2c1

INS-INS-8dbfb37c-1
0.223

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O=S1(=O)C=CC(Nc2cccc(Cl)c2)C1

MAK-UNK-752736de-3
0.222

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O=C(CSc1ccccn1)N(c1cncnc1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-66
0.222

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O=C(CC1C=CS(=O)(=O)C1)NC1CCOc2ccccc21

MAK-UNK-752736de-5
0.221

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O=C(CN1CCN(C(=O)CCl)CC1)Nc1ccc(F)cc1

MAR-TRE-6a44bbf2-47
0.218

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O=S1(=O)C=CC(NCc2ccccc2)C1

MAK-UNK-752736de-12
0.217

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CN(CC1CCN(c2ccc(S(N)(=O)=O)cc2)CC1)c1ccc(F)cc1

WAR-XCH-b6889685-5
0.217

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CC(C)N(C(=O)CCl)c1ccccc1

SAD-SAT-d8079f6f-10
0.215

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CN(c1ccc(F)cc1)C1CCN(c2ccc(S(N)(=O)=O)cc2)CC1

WAR-XCH-b6889685-57
0.215

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CC(=O)NCCC1=CC(C=O)(CCl)c2ccc(F)cc21

ASH-SAT-43770c7d-8
0.214

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O=C(Nc1ccccc1)N(c1ccc(F)cc1)c1cccnc1

WIL-UNI-5578df48-7
0.212

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O=C(CSc1ccccn1)N(c1ccncc1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-45
0.211

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O=C(CSc1ccccn1)N(c1ccc(=O)[nH]c1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-46
0.211

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O=C(CCl)C1CCN(S(=O)(=O)c2cccc(F)c2)CC1

BEN-DND-76ad4ac9-6
0.211

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O=C(CCl)N1CCN(Cc2cccc(CCCNc3c[nH]c4ccc(F)cc34)c2)CC1

MAK-UNK-176ca439-7
0.210

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O=C(CSc1ccccn1)N(c1ncno1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-35
0.209

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C=CC(=O)N1CCN(Cc2ccc(F)cc2)CC1

ANT-OPE-d972fbad-1
0.208

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O=C(CCCc1nc(O)oc1CCl)c1ccc(F)cc1

MAR-TRE-8a25d817-24
0.207

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CC(C)(C)OC(=O)N(C(=O)N(c1ccccc1)c1ccc(F)cc1)c1cccnc1

WIL-UNI-5578df48-34
0.207

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CN(C)c1ccc(C(CNC(=O)C2CCN(C(=O)CCl)CC2)N(C)C)cc1

SAD-SAT-29425be4-19
0.207

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O=C(CSc1ccccn1)N(c1ccoc1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-4
0.207

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O=C(CSc1ccccn1)N(c1cc[nH]n1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-12
0.207

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O=C(CSc1ccccn1)N(c1cc[nH]c(=O)c1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-49
0.206

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NC(=O)CCN(C(=O)CCl)C1CCS(=O)(=O)C1

DAN-PUR-6788a628-2
0.205

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N=C(N)CCN(C(=O)CCl)C1CCS(=O)(=O)C1

DAN-PUR-6788a628-1
0.205

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O=C(Cc1ccc(F)cc1)NCCNC(=O)c1cncnc1

MAR-TRE-4f781e27-85
0.205

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O=C(CSc1ccccn1)N(c1ccsc1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-6
0.204

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O=C(CSc1ccccn1)N(c1cc[nH]c1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-1
0.204

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O=C(CSc1ccccn1)N(c1cn[nH]c1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-13
0.204

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CN1CCC[C@H]1C(=O)NCCc1c[nH]c2ccc(F)cc12

NAU-LAT-81109c57-4
0.204

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CS(=O)(=O)CCN(C(=O)CCl)c1ccc(CO)cc1

THO-SYG-98fc3427-3
0.203

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C=CC(=O)NC1CCN(Cc2ccc(F)cc2)CC1

AHN-SAT-02ef6d10-2
0.203

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CC(=O)NCCc1c[nH]c2ccc(F)cc12

AAR-POS-d2a4d1df-2
0.203

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Cc1c(C(=O)CCl)c2ccccn2c1C(=O)c1ccc(F)cc1

TAT-ENA-80bfd3e5-4
0.202

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O=C(CCl)N(c1ccc(C2CCCCC2)nc1)c1ccc2ncccc2c1

IAN-BAS-b0010df8-1
0.202

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O=C1CCCN1C1CS(=O)(=O)CC1C1c2ccc(F)cc2C(c2ccccc2)CN1C(=O)CCl

DAV-CRI-f4772df7-2
0.202

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O=C(CSc1ccccn1)N(c1cccc(=O)[nH]1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-47
0.200

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O=C(CSc1ccccn1)N(c1nccc(=O)[nH]1)C1CCS(=O)(=O)C1

NJA-MAN-00c90aa2-54
0.200

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CC(=O)N(C(=O)CCl)c1cncc(N)c1

DAN-PUR-19f24f0c-2
0.200

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CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.696

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CS(=O)(=O)CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.672

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CC(=O)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.667

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CC(Cl)(Cl)C(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.661

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CCS(=O)(=O)CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.661

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CCC(CC)(CC)SCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.656

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O=C(CSCCC(F)(F)F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.651

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O=C(CSC1=CC=C(F)C=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.650

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CC(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.650

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O=C(CS(=O)(=O)C1CC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.650

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O=C(CSCCO)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.650

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CC(C)(C)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.645

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CC(C)(C)C(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.645

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N#CN(CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1=CC=C(F)C=C1

0.639

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O=C(CS(=O)(=O)C(F)F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.639

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O=C(CSC1CCC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.629

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CCC(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.629

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CC(C)C(C)SCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.629

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CC(C)(C)C(=O)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.625

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O=C(CSC1=CC=CC=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.619

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CCC(CC)SCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.619

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O=C(CSCC1CC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.619

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CC(C)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.619

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O=C(CSC1COC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.619

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CC(C)C(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.619

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O=C(CSC1=CC=C(Cl)C=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.615

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O=C(CSC1=C(Cl)C=CC=C1Cl)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.615

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O=C(CSCC1CC1(Cl)Cl)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.615

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O=C(CSC1CCCC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.609

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O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1CC1

0.609

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CC(=O)C(C)SCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.609

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O=C(CSC1=C(F)C=C(F)C=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.609

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O=C(CS(=O)(=O)CC1CC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.609

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O=C(CSC1=CC=C(O)C=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.609

View
O=C1C2=CC=CC=C2C(=O)N1CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.606

View
O=C(CN1C=NC(Cl)=C1Cl)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.606

View
CC(=CCl)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.606

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1=CC=C(F)C=C1

0.600

View
NC(=O)CCSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.600

View
CCSCCSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.600

View
CCN(CC)C(=O)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.600

View
COCC(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.600

View
CC1=CC=C(SCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.600

View
COC(=O)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.600

View
CNC(=O)CSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.600

View
CC(SCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1=CC=C(F)C=C1

0.600

View
O=C(COC1=CC=C(Cl)C=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.597

View
O=C(CSC1=CC=CC=C1Cl)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.597

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1CC1(Cl)Cl

0.597

View
CC(C)(C)OCC(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.597

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1CC1F

0.591

View
O=C1CCCCC(=O)N1CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
O=C(CSC1CCCCC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
O=C(CSC1=NC=CC=N1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
O=C(CSC1=CC=CC=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
O=C(CSC1=CC(F)=CC=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
O=C(CSC1=CC=NC=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
O=C(COC(=O)C1(F)CC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
COCCSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
CCCC(CCC)SCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
CCCC(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.591

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1CCC1

0.591

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1CC1(F)F

0.591

View
O=C(COC1=C(Cl)C=CC=C1Cl)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.588

View
O=C(COC1=CC(Cl)=CC(Cl)=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.588

View
O=C(COC1=C(F)C=CC=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.582

View
O=C(CSC1=CC=C(F)C=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.582

View
O=C(CS(=O)(=O)C1=CC=CC=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.582

View
O=C(CSC1=CC=C(F)C(F)=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.582

View
O=C(CSCC1CCCC1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.582

View
N#CN(CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1=CC=CC=C1

0.582

View
CC1CC1C(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.582

View
O=C(CC1CC1)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.582

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1CC=CC1

0.582

View
O=C(COC1=CC=CC=C1Cl)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.580

View
O=C(CSCC1=CC=C(Cl)C=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.580

View
O=C(COC1=CC=C(Br)C=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.574

View
O=C(CSCC1=C(F)C=CC=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.574

View
O=C(CC1=CC=C(F)C=C1)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.574

View
O=C(CSCC1=CC=CC=C1)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.574

View
O=C(COC1=CC=CC=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.574

View
NC1=CC(N)=NC(SCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)=N1

0.574

View
O=C(COC1=C(F)C(F)=CC(F)=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.574

View
CN(C)CCCSCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.574

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1CCCC1

0.574

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1=CC(F)=CC(F)=C1

0.574

View
O=C(COC1=CC=C(F)C=C1Cl)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.571

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1=CC=C(Cl)C=C1

0.571

View
O=CC1=CC=C(OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.565

View
NC(=O)C1=CC=C(OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.565

View
O=C(COC1=CC(F)=CC=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.565

View
O=C(CC1C=CS(=O)(=O)C1)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.565

View
O=C(COC1=CC=C(F)C=C1F)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.565

View
O=C(OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1)C1=CC=CC=C1

0.565

View
O=C(COC1=CC=C(F)C=C1)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.557

View
CC(=O)C1=CC=C(OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.557

View
N#CC1=CC=C(OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.557

View
NC1=C(F)C=CC(F)=C1C(=O)OCC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.548

View
NS(=O)(=O)C1=CC=C(OCC(=O)N(C2=CC=C(F)C=C2)C2C=CS(=O)(=O)C2)C=C1

0.542

View
O=C1C2=CC=C(F)C=C2C(=O)N1CC(=O)N(C1=CC=C(F)C=C1)C1C=CS(=O)(=O)C1

0.542

View
Fc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:14|

1.000

View
CCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:10|

0.736

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:14|

0.717

View
CCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:11|

0.696

View
COCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:11|

0.684

View
ClCC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:10|

0.667

View
COc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:15|

0.667

View
CCCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:12|

0.661

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:9|

0.660

View
CCOc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:16|

0.644

View
Fc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)Cc1ccccc1 |c:14|

0.629

View
Fc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(F)(F)F |c:14|

0.625

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:11|

0.625

View
CC(C)(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:12|

0.614

View
Fc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)COc1ccccc1 |c:14|

0.609

View
CCC(CC)C(=O)N(C1CS(=O)(=O)C=C1)c1ccc(F)cc1 |c:13|

0.600

View
Cc1ccc(cc1C)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:15|

0.593

View
Fc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C1CC1 |c:14|

0.586

View
Cc1cccc(c1)N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:14|

0.557

View
Fc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C1CCCC1 |c:14|

0.548

View
CCC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:10|

0.475

View
CCc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(C)=O |c:15|

0.475

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(Cl)cc1 |c:9|

0.467

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(C)cc1 |c:9|

0.458

View
CCc1ccccc1N(C1CS(=O)(=O)C=C1)C(=O)CCl |c:15|

0.455

View
CCCC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:11|

0.453

View
CC(C)c1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(C)=O |c:16|

0.452

View
COCC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:11|

0.446

View
Cc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(Cl)(Cl)Cl |c:14|

0.444

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccc(Br)cc1 |c:9|

0.443

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:9|

0.433

View
FC(F)(F)C(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:12|

0.429

View
COc1ccc(cc1)N(C1CS(=O)(=O)C=C1)C(=O)C(Cl)(Cl)Cl |c:15|

0.418

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc(C)c1 |c:9|

0.400

View
CC(Cl)C(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:11|

0.394

View
CC(C)C(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1 |c:11|

0.391

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc(Cl)c1 |c:9|

0.388

View
FC(F)(F)c1cccc(c1)N(C1CS(=O)(=O)C=C1)C(=O)C(Cl)(Cl)Cl |c:17|

0.370

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1ccccc1C |c:9|

0.369

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc(Br)c1 |c:9|

0.368

View
CC(=O)N(C1CS(=O)(=O)C=C1)c1cccc2ccccc12 |c:9|

0.347

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CC

0.525

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CSC

0.516

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CSCC

0.500

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CCC

0.500

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CC#C

0.492

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)COC

0.492

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CC#N

0.484

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CC=C

0.484

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CCSC

0.477

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)CCC=C

0.463

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(=O)C

0.458

View
C(N(C1=CC=C(C)C=C1)C1C=CS(=O)(=O)C1)(C(Cl)Cl)=O

0.444

View
C(N(C1C=CS(=O)(=O)C1)C1=CC=CC(Cl)=C1)(=O)CC

0.426

View
C(N(C1C=CS(=O)(=O)C1)C1=CC=CC(Cl)=C1)(=O)CSC

0.423

View
C(N(C1C=CS(=O)(=O)C1)C1=CC=CC(Cl)=C1)(=O)CSCC

0.417

View
C(N(C1C=CS(=O)(=O)C1)C1=CC=CC(Cl)=C1)(=O)CC#N

0.403

View
C(N(C1C=CS(=O)(=O)C1)C1=CC=CC(Cl)=C1)(=O)CC=C

0.403

View
C(N(C1C=CS(=O)(=O)C1)C1=CC=CC(Cl)=C1)(=O)C

0.388

View
C(N(C1C=CS(=O)(=O)C1)C1=CC=CC(Cl)=C1)(C(Cl)Cl)=O

0.357

View
N(C1C=CS(=O)(=O)C1)(C1=CC=CC=C1)CC

0.323

View


Discussion: