Molecule Details

O=C1NC(c2cccnc2)C(=O)N1c1cccc(Cl)c1
3-aminopyridine-like Enamine Assayed
View on Fragalysis x10535
Molecular Properties
SMILES:
O=C1NC(c2cccnc2)C(=O)N1c1cccc(Cl)c1
MW: 287.706
Fraction sp3: 0.07
HBA: 3
HBD: 1
Rotatable Bonds: 2
TPSA: 62.3
cLogP: 2.5325
Covalent Warhead:
Covalent Fragment:
Source
Enamine Extended REAL: s_272126____9348554____13258892
Activity Data
IC50 (µM) - RapidFire: 57.8484231374202
Average Inhibition @ 20 µM - Fluorescence: 18.107195
Average Inhibition @ 50 µM - Fluorescence: 33.925115
Average Inhibition @ 50 µM - RapidFire: 69.5562188171954
Relative Solubility @ 20 µM: 0.85
Relative Solubility @ 100 µM: 0.91
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: 2020-06-16

hydantoin

O=C(CC1CCCCC1)Nc1cccnc1

ALE-HEI-f28a35b5-9

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Cc1ccncc1C1CCN(c2cccc(Cl)c2)C1=O

EDJ-MED-e66f2cc5-2
0.400

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O=C1NC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-17
0.373

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O=C1NC(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

VLA-UCB-1dbca3b4-11
0.366

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Cc1ccncc1C1CCN(c2cccc(Cl)c2)S1(=O)=O

EDJ-MED-49816e9b-6
0.354

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O=C1CC(c2cccnc2)CCN1c1ccccc1

DAR-DIA-fc970077-4
0.351

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O=C1c2cc(F)c(Cl)cc2N(c2ccccc2)C(=O)C1c1cccnc1

MAK-UNK-9e4a73aa-2
0.345

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O=C1NC(c2cccnc2)CCN1c1ccccc1

DAR-DIA-fc970077-2
0.342

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O=C1C(c2cccc(Cl)c2)N(Cc2ccccc2)CCN1c1cccnc1

ERI-UCB-ce40166b-24
0.341

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O=C1C(c2cccc(Cl)c2)N(CC2CCCCC2)CCN1c1cccnc1

ERI-UCB-ce40166b-22
0.341

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O=C(Nc1cccnc1)c1cccc(Cl)c1

CHR-SOS-7098f804-12
0.338

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COC(=O)C1C(=O)C[C@H](Cc2cccc(Cl)c2)O[C@H]1c1cccnc1

NIM-UNI-b87c0f72-2
0.337

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COC(=O)C1C(=O)C[C@@H](Cc2cccc(Cl)c2)O[C@H]1c1cccnc1

NIM-UNI-b87c0f72-1
0.337

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Cc1ccncc1N1CCN(c2cccc(Cl)c2)C1=O

JAG-UCB-cedd89ab-1
0.333

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Cc1ccncc1N1C(=O)CC(c2cccc(Cl)c2)C1=O

VLA-UCB-1dbca3b4-4
0.333

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O=c1c2cc(F)c(Cl)cc2n(-c2cccc(Cl)c2)c(=O)n1-c1cccnc1

RAI-NOV-c18e0037-3
0.333

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Cc1ccncc1N1CCC(c2cccc(Cl)c2)C1=O

EDJ-MED-e66f2cc5-1
0.329

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CN1CCCC1c1cccnc1

KTA-UNK-dac325de-1
0.323

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O=C1c2ccc(Cl)cc2C(=O)N1c1cccnc1

MAR-TRE-74c6519b-18
0.315

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CNCC1CC1(C(=O)Nc1cccnc1)c1cccc(Cl)c1

ADA-UNI-f8e79267-12
0.310

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N#Cc1cccc(N2CCN(C(=O)CCl)C(c3cccnc3)C2=O)c1

MIC-UNK-df342a3f-1
0.308

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O=C(Nc1cccnc1)Nc1cccc(Cl)c1

WAR-XCH-eb7b662f-7
0.306

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O=C(Nc1cccnc1)Nc1cccc(Cl)c1

DAR-DIA-23aa0b97-14
0.306

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O=C(Nc1cccnc1)Nc1cccc(Cl)c1

JAN-GHE-83b26c96-19
0.306

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O=C(Nc1cccnc1)Nc1cccc(Cl)c1

JOR-UNI-2fc98d0b-7
0.306

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O=C(COCC(=O)N1CCN(c2cccc(Cl)c2)CC1)Nc1cccnc1

MAR-TRE-d0525fbf-84
0.304

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C=C(C(=O)Nc1cccc(Cl)c1)c1cccnc1

BEN-DND-61647d40-20
0.303

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NC(=O)[C@H]1[C@@H](c2cccc(Cl)c2)C=C(Cc2cccnc2)[C@@H]1O

DAR-DIA-43a5904b-6
0.302

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NC(=O)[C@H]1C(O)C(Cc2cccnc2)=C[C@H]1c1cccc(Cl)c1

DAR-DIA-43a5904b-5
0.302

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O=C(NCC(=O)N1CCN(c2cccc(Cl)c2)CC1)Nc1cccnc1

SAD-SAT-135344c3-8
0.300

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O=C1c2cc(F)c(Cl)cc2C(c2ccccc2)C(=O)N1c1cccnc1

MAK-UNK-9e4a73aa-3
0.299

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Cc1ccncc1N1CCC(c2cccc(Cl)c2)S1(=O)=O

EDJ-MED-49816e9b-4
0.298

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O=C1NCC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-18
0.297

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O=C1NC[C@@H](c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

PET-UNK-abc197b8-1
0.297

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O=C(Nc1cccnc1)N(CN1CCC(O)CC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-3
0.297

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O=C1C(c2ccccc2)CCCN1c1cccnc1

DAR-DIA-fc970077-7
0.295

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COc1ccccc1[C@@H]1CN(c2cccc(Cl)c2)C(=O)N(c2cnccc2C)C1

ADA-UCB-6c2cb422-7
0.295

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O=C(Nc1cccnc1)N(CCC1CC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-8
0.294

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O=C(Cc1cccc(Cl)c1)Nc1cccnc1

EDG-MED-0da5ad92-2
0.293

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O=C(Nc1cccc(Cl)c1)[C@@]1(c2cccnc2)CO1

BEN-DND-61647d40-19
0.291

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CC1CCN(CN(C(=O)Nc2cccnc2)c2cccc(Cl)c2)CC1

JOR-UNI-2fc98d0b-14
0.290

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Cc1ccncc1-c1cc(C#N)cn(-c2cccc(Cl)c2)c1=O

ADA-UCB-6c2cb422-6
0.287

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O=C1N(c2cccnc2)Cc2cc(F)c(Cl)cc2N1c1ccccc1

RAI-NOV-c18e0037-6
0.287

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O=C(Nc1cccnc1)c1ccc(CNS(=O)(=O)c2cccc(Cl)c2)cc1

MAR-TRE-04c86cea-65
0.286

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NC(=O)[C@H]1CC(Cc2cccnc2)=C[C@H]1c1cccc(Cl)c1

DAR-DIA-43a5904b-1
0.284

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O=C(Nc1cccnc1)N(CN1CCNCC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-4
0.283

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O=C1C[C@@H](c2cccc(Cl)c2)C(=O)N1c1nncn1C1CC1

VLA-UCB-53bdeed6-1
0.282

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O=C1C(c2ccccc2)C=CCN1c1cccnc1

DAR-DIA-fc970077-12
0.282

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O=C1Nc2cnccc2C12CCC2Cc1cccc(Cl)c1

SAD-SAT-7d5528d9-47
0.279

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O=C(Nc1cccc(Cl)c1)C(c1cccnc1)N1C(=O)C=CC1=O

JAN-GHE-d851b096-2
0.279

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O=C(CCl)CC1CNC(=O)N1c1cccnc1

NIM-UNI-0ea3b7bf-5
0.278

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O=C1C(c2ccccc2)OCCN1c1cccnc1

DAR-DIA-fc970077-8
0.278

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O=C(CCl)N1CCN(c2cccc(Cl)c2)CC1

SAD-SAT-65574d3f-9
0.278

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O=S1(=O)CC(Nc2cccc(Cl)c2)C=N1

MAK-UNK-942dcb71-5
0.278

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O=C(Nc1cccnc1)N(CCN1CCC(O)CC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-13
0.277

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O=C(CCl)N1Cc2ccccc2C(c2cccc(Cl)c2)C1Cc1cccnc1

DAV-CRI-1c77f7a9-4
0.276

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O=C(Nc1cccnc1)N(CN1CCCCC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-16
0.275

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CS(=O)(=O)NCC1CC1(C(=O)Nc1cccnc1)c1cccc(Cl)c1

ADA-UNI-f8e79267-9
0.275

View
O=C1CC(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

VLA-UCB-1dbca3b4-8
0.273

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O=C(NCC(=O)N1CCN(c2cccc(Cl)c2)CC1)c1cncnc1

MAR-TRE-a9136c7b-76
0.273

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O=C(Nc1cccnc1)N(CCC1CCCCC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-12
0.272

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O=c1c2cc(F)c(Cl)cc2n(-c2cccnc2)c(=O)n1-c1cccnc1

MAK-UNK-9e4a73aa-18
0.272

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CC1CCN(CCN(C(=O)Nc2cccnc2)c2cccc(Cl)c2)CC1

JOR-UNI-2fc98d0b-15
0.271

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O=C1c2cc(F)c(Cl)cc2C(c2ccccc2)C(=O)C1c1cccnc1

MAK-UNK-9e4a73aa-5
0.271

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[O-][S+](Cc1cccnc1)Cc1cccc(Cl)c1

MIC-UNK-5ce21166-1
0.270

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O=C1Nc2cnccc2C12CCN(Cc1cccc(Cl)c1)CC2

SAD-SAT-7d5528d9-49
0.270

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Cc1ccncc1NS(=O)(=O)c1cccc(Cl)c1

JAN-GHE-83b26c96-21
0.269

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O=C1CCC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-10
0.269

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CN1CCN(CN(C(=O)Nc2cccnc2)c2cccc(Cl)c2)CC1

JOR-UNI-2fc98d0b-5
0.269

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O=C(Nc1cccnc1)N(CN1CCOCC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-1
0.269

View
O=C1N(c2ccccc2)CCN1c1cccnc1

DAR-DIA-fc970077-1
0.268

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O=C1N(c2cccc(Cl)c2)CCN1c1cncc2ccccc12

PET-UNK-7be94445-2
0.267

View
O=C(Nc1cccnc1)c1cc(=O)[nH]c(C2CCOCC2)n1

MAR-TRE-2fd8122f-36
0.267

View
O=C1CC(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-6
0.267

View
O=C(NCCN1CCCCC1)[C@H]1CC(Cc2cccnc2)=C[C@H]1c1cccc(Cl)c1

DAR-DIA-43a5904b-15
0.267

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Cc1ccncc1NC(=O)[C@@H]1CC(=O)N(C)[C@@H]1c1cccc(Cl)c1

MAR-TRE-4b834d9a-26
0.266

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Cc1ccncc1C1c2ncccc2C(c2cccc(Cl)c2)[S+]1[O-]

MIC-UNK-4e776895-1
0.264

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CNCCC(C(=O)Nc1cccnc1)c1cccc(Cl)c1

ADA-UNI-f8e79267-11
0.264

View
CN1C(=O)CC(NC(=O)c2cncnc2)C1c1cccnc1

MAR-TRE-a9136c7b-47
0.264

View
O=C1CCN(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-13
0.264

View
O=C1C(c2cccc(Cl)c2)CCN1c1cncc2ccccc12

PET-UNK-c9c1e0d8-4
0.264

View
O=C(Nc1cccnc1)N(CCN1CCOCC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-6
0.263

View
O=C(Nc1cccnc1)N(CCN1CCNCC1)c1cccc(Cl)c1

JOR-UNI-2fc98d0b-10
0.263

View
C=CC(=O)N(c1ccc(NC(C)=O)cc1)N(C(=O)Nc1cccc(Cl)c1)c1cccnc1

JAN-GHE-d851b096-3
0.263

View
Cc1ccncc1CC(=O)Nc1cccc(Cl)c1

EDJ-MED-49816e9b-1
0.263

View
O=C1CN(c2cccc(Cl)c2)C(=O)N1c1cncc2ccccc12

VLA-UCB-1dbca3b4-3
0.261

View
O=C1CN(c2cccc(Cl)c2)C(=O)N1c1cccc2[nH]ncc12

VLA-UCB-1dbca3b4-9
0.261

View
O=C(Nc1ccccc1)C1CCN(C(=O)C2OC2c2cccnc2)CC1

BEN-DND-031a96cc-3
0.261

View
O=C1Nc2cnccc2C12CCN(Cc1cccc(Cl)c1)C2

SAD-SAT-7d5528d9-36
0.261

View
O=c1c2ncccc2n(Cc2cccc(Cl)c2)c(=O)n1Cc1cccnc1

MAR-TRE-b77b7921-33
0.261

View
NCCNC(=O)[C@H]1CC(Cc2cccnc2)=C[C@H]1c1cccc(Cl)c1

DAR-DIA-43a5904b-13
0.260

View
O=C(Cc1cccc(Cl)c1)N[C@H]1CCNC1=O

MAT-POS-500ca5bf-2
0.260

View
O=C(Cc1cccc(Cl)c1)NC1CCNC1=O

ALP-POS-90e38439-2
0.260

View
O=C(Cc1cccc(Cl)c1)NC1CCNC1=O

MIC-UNK-42806bd5-1
0.260

View
O=C1CC(NC(=O)Cc2cccc(Cl)c2)CCN1

ALP-POS-8b8a49e1-8
0.259

View
O=C(Nc1cccnc1)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-11
0.259

View
Cc1ccncc1N1C(=O)C=C(c2cccc(Cl)c2)C1=O

VLA-UCB-00f2c2b3-5
0.259

View
O=C(Nc1cccnc1)c1cccc(CN2C(=O)CNC2=O)c1

MAR-TRE-3e4e6814-45
0.258

View
O=C(CCl)Nc1nc(=O)n(Cc2cccc(Cl)c2)cc1-c1cccnc1

MED-COV-4280ac29-3
0.258

View
Cc1ccncc1NC(=O)C1CCN(Cc2cccc(Cl)c2)CC1

SAD-SAT-7d5528d9-7
0.258

View
O=C1Nc2cnccc2C2(Cc3cccc(Cl)c3)CCC1C2

SAD-SAT-7d5528d9-52
0.258

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(Cl)c1

1.000

View
O=C1NC(c2cccnc2)C(=O)N1c1cc(Cl)cc(Cl)c1

0.810

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(Br)c1

0.750

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(I)c1

0.750

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Cl)cc1

0.744

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Oc2cccc(Cl)c2)cc1

0.735

View
Cc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.733

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Cl)c(Cl)c1

0.733

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(F)c1

0.733

View
O=C1NC(c2cccnc2)C(=O)N1c1cccnc1

0.732

View
Cc1c(N2C(=O)NC(c3cccnc3)C2=O)cnn1-c1cccc(Cl)c1

0.725

View
Cc1cc(N2C(=O)NC(c3cccnc3)C2=O)nn1-c1cccc(Cl)c1

0.725

View
O=C1NC(c2cccnc2)C(=O)N1c1cc(F)cc(Cl)c1

0.723

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(Sc2ccc(Cl)cc2)c1

0.720

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(-c2ccccc2)c1

0.717

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(-n2cccc2)c1

0.717

View
O=C1NC(c2ccccc2)C(=O)N1c1cccc(Cl)c1

0.714

View
O=C1NC(c2cccnc2)C(=O)N1c1ccccc1

0.714

View
O=C1N[C@H](c2ccccc2)C(=O)N1c1cccc(Cl)c1

0.714

View
C#Cc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.702

View
COc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.702

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(C(F)(F)F)c1

0.702

View
CC(C)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.702

View
Cc1c(Cl)cc(N2C(=O)NC(c3cccnc3)C2=O)cc1Cl

0.696

View
O=C1NC(c2cccnc2)C(=O)N1c1cc(Cl)cc(C(F)(F)F)c1

0.694

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(C(F)F)c1

0.688

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(N2CCCC2)c1

0.688

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Br)c(Cl)c1

0.688

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(S(F)(F)(F)(F)F)c1

0.688

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Cl)c(F)c1

0.688

View
CSc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.688

View
Cc1ccc(N2C(=O)NC(c3cccnc3)C2=O)cc1Cl

0.688

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(F)c(Cl)c1

0.688

View
N#Cc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.688

View
CCc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.688

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(C2CCC2)c1

0.688

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Cl)c(Br)c1

0.688

View
O=C1NC(c2cccnc2)C(=O)N1c1cc(Cl)ccc1Cl

0.681

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Cl)cc1Cl

0.681

View
Nc1c(Cl)cc(N2C(=O)NC(c3cccnc3)C2=O)cc1Cl

0.681

View
O=C1NC(c2cccnc2)C(=O)N1c1csc(Cl)c1

0.681

View
Cc1cc(N2C(=O)NC(c3cccnc3)C2=O)cc(C)c1Cl

0.681

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(CCCc2ccccc2)c1

0.680

View
O=C1NC(c2ccc(Cl)cc2)C(=O)N1c1cccc(Cl)c1

0.674

View
O=C1NC(c2cccnc2)C(=O)N1c1ccncc1

0.674

View
CS(=O)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.673

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(N2CCCCC2)c1

0.673

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(C2SCCS2)c1

0.673

View
CS(=O)(=O)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.673

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(C#Cc2ccccc2)c1

0.673

View
O=C(c1ccccc1)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.673

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(-n2cccn2)c1

0.673

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc([N+](=O)[O-])c1

0.673

View
NS(=O)(=O)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.673

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(Oc2ccccc2)c1

0.673

View
CC(=O)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.673

View
NC(=O)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.673

View
CCSc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.673

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(N2CCCCCC2)c1

0.673

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(Sc2ccccc2)c1

0.673

View
O=C1NC(c2ccc(Cl)cc2)C(=O)N1c1cccnc1

0.667

View
CN(C)S(=O)(=O)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.667

View
COC(=O)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.667

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(OCc2ccc(Cl)cc2)c1

0.667

View
Cc1ccc(N2C(=O)NC(c3cccnc3)C2=O)cc1OCc1cccc(Cl)c1

0.661

View
COC(=O)c1cc(Cl)cc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.660

View
COCc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.660

View
O=C1NCCN1c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.660

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(-c2cccs2)c1

0.660

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Cl)c(C(F)(F)F)c1

0.660

View
COc1ccc(N2C(=O)NC(c3cccnc3)C2=O)cc1Cl

0.660

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(-c2ccc(Br)cc2)c1

0.660

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(Oc2ccncc2)c1

0.660

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(CC(F)(F)F)c1

0.660

View
O=C1CC(c2cccc(N3C(=O)NC(c4cccnc4)C3=O)c2)CN1

0.660

View
CC(C)(C)Oc1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.660

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(-n2ccnn2)c1

0.660

View
O=C1CCN1c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.660

View
Cc1ccc(N2C(=O)NC(c3cccnc3)C2=O)cc1C

0.660

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc2ccccc2c1

0.660

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(F)c(F)c1

0.660

View
Cc1cc(N2C(=O)NC(c3cccnc3)C2=O)ccn1

0.660

View
Cc1cc(-c2cccc(Cl)c2)ccc1N1C(=O)NC(c2cccnc2)C1=O

0.654

View
O=C1OCCN1c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.654

View
COc1c(Cl)cc(N2C(=O)NC(c3cccnc3)C2=O)cc1Cl

0.653

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc(Sc2ccc(Cl)cc2)cc1

0.653

View
O=C1NC(c2cccnc2)C(=O)N1c1ccc2c(c1)OCCO2

0.653

View
COc1ccc(N2C(=O)NC(c3cccnc3)C2=O)cc1OC

0.653

View
Cc1ccc(Cl)cc1N1C(=O)NC(c2cccnc2)C1=O

0.653

View
O=C1NC(c2cccnc2)C(=O)N1c1cc(F)cc(F)c1

0.652

View
O=C1NC(c2cccc(O)c2)C(=O)N1c1cccc(Cl)c1

0.652

View
Cc1cc(C)cc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.652

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(-c2ccc(=O)[nH]n2)c1

0.647

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(SC(F)F)c1

0.647

View
CSc1ccc(N2C(=O)NC(c3cccnc3)C2=O)cc1Cl

0.647

View
CN(C)c1ccc(N2C(=O)NC(c3cccnc3)C2=O)cc1Cl

0.647

View
Cc1ccnn1-c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.647

View
CN(C)C(=O)c1cccc(N2C(=O)NC(c3cccnc3)C2=O)c1

0.647

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(OC(F)(F)F)c1

0.647

View
O=C1NC(c2cccnc2)C(=O)N1c1cccc(OC(F)F)c1

0.647

View

C(N(C(N(C)O)=O)C1=CC=CC(Cl)=C1)(=O)CC1=CC=CN=C1

0.740

View
C(N(C(N(C)O)=O)C1=CC=C(Cl)C=C1)(=O)CC1=CC=CN=C1

0.703

View
C(N1CCN(C2=CC=C(Cl)C(Cl)=C2)C1=O)(=O)CC1=CC=CN=C1

0.703

View


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