Molecule Details

O=C(Cc1cncnc1)Nc1cccc(OC2CC(=O)N2)c1
3-aminopyridine-like Enamine Mcule MolPort Assayed
View on Fragalysis x2562
Molecular Properties
SMILES:
O=C(Cc1cncnc1)Nc1cccc(OC2CC(=O)N2)c1
MW: 298.302
Fraction sp3: 0.2
HBA: 5
HBD: 2
Rotatable Bonds: 5
TPSA: 93.21
cLogP: 0.8826
Covalent Warhead:
Covalent Fragment:
Source
Enamine BB: EN300-26689860
Enamine SCR: Z4444622180
Enamine Extended REAL: s_22____10971742____13540170
Mcule: MCULE-5359414809
MolPort: MolPort-047-358-913
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 7.863298
Average Inhibition @ 50 µM - Fluorescence: 22.773735
Average Inhibition @ 20 µM - RapidFire: -2.075
Average Inhibition @ 50 µM - RapidFire: 8.105
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-03-31
Synthesis Location: enamine
Shipped: 2020-04-17

betalactam

b-lactam

O=C(Cc1cccnc1)Nc1cccc(OC2CC(=O)N2)c1

RAL-MED-2de63afb-1
0.761

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O=C(Cc1ccccc1)Nc1cccc(OC2CC(=O)N2)c1

RAL-MED-2de63afb-6
0.691

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Cc1cc(NC(=O)Cc2cncnc2)cc(OC2CC(=O)N2)c1

RAL-MED-2de63afb-2
0.644

View
CCC(=O)Nc1cccc(OC2CC(=O)N2)c1

RAL-MED-2de63afb-11
0.636

View
O=C(Cc1cncnc1)Nc1cc(F)cc(OC2CC(=O)N2)c1

RAL-MED-2de63afb-14
0.630

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N#Cc1cc(NC(=O)Cc2cncnc2)cc(OC2CC(=O)N2)c1

TRY-UNI-bbd40bb4-1
0.613

View
O=C1CC(Oc2cccc(NC(=O)C(=O)c3cncnc3)c2)N1

RAL-MED-2de63afb-4
0.595

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O=C(Cc1cncnc1)Nc1cccc(CC2CC(=O)N2)c1

RAL-MED-2de63afb-7
0.589

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C[C@H](C(=O)Nc1cccc(OC2CC(=O)N2)c1)c1cncnc1

RAL-MED-2de63afb-16
0.587

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C[C@@H](C(=O)Nc1cccc(OC2CC(=O)N2)c1)c1cncnc1

RAL-MED-2de63afb-15
0.587

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O=C(Cc1cncc2ccccc12)Nc1cccc(OC2CC(=O)N2)c1

ERI-UCB-ce40166b-1
0.578

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C=CC(=O)Nc1cccc(OC2CC(=O)N2)c1

RAL-MED-2de63afb-9
0.565

View
O=C1CC(c2cccc(NC(=O)Cc3cncnc3)c2)CN1

RAL-MED-2de63afb-3
0.553

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O=C(Cc1cncnc1)Nc1cccc(CC2CCC(=O)N2)c1

RAL-MED-2de63afb-8
0.545

View
O=C(Cc1cncnc1)Nc1cccc([C@H]2NCCNC2=O)c1

ADA-UCB-b1b30a00-3
0.532

View
O=C(Cc1cncnc1)Nc1cccc(CC2CNC(=O)N2)c1

RAL-MED-2de63afb-13
0.526

View
C/C=C/C(=O)Nc1cccc(OC2CC(=O)N2)c1

RAL-MED-2de63afb-10
0.521

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O=C(Cc1cncnc1)Nc1cccc(N2CCC2)c1

SAD-SAT-24589cd1-2
0.514

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O=C(Cc1cccnc1)Nc1cccc(OC2CC(=NO)C2)c1

ANT-OPE-6e66bf84-1
0.506

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CC(C(=O)Nc1cccc(OC2CC(=O)N2)c1)c1cnccn1

BAR-COM-4e090d3a-53
0.506

View
O=C1CC(Oc2cccc(C(=O)NCc3cncnc3)c2)N1

RAL-MED-2de63afb-5
0.500

View
CON=C1CC(Oc2cccc(NC(=O)Cc3cccnc3)c2)C1

ANT-OPE-6e66bf84-2
0.494

View
O=C(Cc1cncnc1)Nc1cccc(CCCc2ccccc2)c1

BAR-COM-4e090d3a-11
0.487

View
O=C(Cc1cncnc1)Nc1cccnc1

SAD-SAT-24589cd1-4
0.485

View
O=C(Cc1cncc2ccccc12)Nc1cccc(OC2CCC(=O)N2)c1

ERI-UCB-ce40166b-2
0.484

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-7
0.476

View
Cc1ccncc1NC(=O)Cc1cccc(OC2CC(=O)N2)c1

BRU-LEF-c49414a7-1
0.476

View
CC(=O)NCc1cccc(NC(=O)Cc2cncnc2)c1

RAL-MED-2de63afb-12
0.474

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C=CC(=O)N(C(=O)Cc1cccc(OC2CC(=O)N2)c1)c1cncnc1

TRY-UNI-69298daf-3
0.437

View
Cc1ccncc1CC(=O)Nc1cc(C#N)cc(OC2CC(=O)N2)c1

TRY-UNI-bbd40bb4-2
0.433

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Cc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-1
0.416

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COc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-5
0.396

View
CCc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-6
0.396

View
Cc1ccncc1NC(=O)Cc1cc(F)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-2
0.391

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-7
0.391

View
Cc1ccncc1NC(=O)Cc1cc(Cl)cc(OC2CC(=O)N2)c1

WIL-MOD-03b86a88-1
0.391

View
O=C(Cc1cncc2ccccc12)Nc1cc(Cl)cc(OC2CC(=O)N2)c1

ERI-UCB-ce40166b-5
0.388

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N#Cc1cc(NC(=O)Cc2cncc3ccccc23)cc(OC2CC(=O)N2)c1

ERI-UCB-ce40166b-9
0.384

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C=CC(=O)N(C(=O)Cc1cccc(OC2CC(=O)N2)c1)c1cccnc1

TRY-UNI-69298daf-5
0.380

View
Cc1ccncc1NC(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-3
0.379

View
Cc1ccncc1NC(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-6
0.379

View
C#Cc1cc(CC(=O)Nc2cnccc2C)cc(OC2CC(=O)N2)c1

RAL-THA-901e9a10-4
0.379

View
C=CC(=O)N(C(=O)Cc1cccc(OC2CC(=O)N2)c1)c1cnccc1C

TRY-UNI-69298daf-1
0.375

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N#Cc1cccc(NC(=O)Cc2cccnc2)c1

DAR-DIA-23aa0b97-4
0.375

View
O=C(Cc1cncnc1)NC(=O)C1CC1

MAK-UNK-748f8b7a-14
0.366

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CN(C)C(NC(=O)Cc1cncnc1)C1CCC1

MAK-UNK-748f8b7a-3
0.364

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O=C1CC(Oc2ccc(NC(=O)Nc3cccnc3)s2)N1

TRY-UNI-bbd40bb4-4
0.356

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NC(NC(=O)Cc1cncnc1)C1CC1

MAK-UNK-748f8b7a-16
0.351

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cncc2ccccc12

MAT-POS-3b92565d-3
0.350

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O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cncc2ccccc12

ALP-POS-3b848b35-2
0.350

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cncc2ccccc12

EDJ-MED-7320d5d2-1
0.350

View
COc1cccc(NC(=O)Cc2cccc(CS(N)(=O)=O)c2)c1

CHA-MCP-85291e1d-6
0.349

View
Cc1ccncc1NC(=O)Cc1ccc(Cl)c(OC2CC(=O)N2)c1

RAL-THA-901e9a10-8
0.347

View
O=C(Cc1cn[nH]c1)Nc1cccc(Cl)c1

MIC-UNK-66895286-2
0.338

View
COc1cccc(NC(=O)Cc2cccc(CCNC(C)=O)c2)c1

CHA-MCP-85291e1d-3
0.337

View
CC(NC(=O)Cc1cncnc1)NC1COCC1O

MAK-UNK-748f8b7a-10
0.333

View
O=C(Cc1cccc(Cl)c1)Nc1cncnc1

JAN-GHE-5a013bed-9
0.333

View
O=C(Cc1cncnc1)NC1CCNCC1

MAK-UNK-748f8b7a-15
0.333

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1nc2ccccc2[nH]1

ALP-POS-a30bcdb4-1
0.330

View
C=CC(=O)N(C(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1)c1cncnc1

TRY-UNI-69298daf-4
0.330

View
Cc1ccncc1NC(=O)N(C)c1cc(Cl)cc(OC2CC(=O)N2)c1

MAR-UCB-ad2ff052-1
0.327

View
N#Cc1cccc(NC(=O)Cc2cncc(N)c2)c1

DAR-DIA-23aa0b97-3
0.326

View
O=C(Cc1cncc2ccccc12)Nc1cc(Cl)cc(OC2CCC(=O)N2)c1

ERI-UCB-ce40166b-6
0.324

View
O=C(Cc1cccnc1Cl)Nc1cccc(OCCc2ccccc2)c1

BAR-COM-4e090d3a-15
0.323

View
Cc1ccncc1NC(=O)Nc1ccc(OC2CC(=O)N2)s1

TRY-UNI-bbd40bb4-6
0.323

View
N#Cc1cc(NC(=O)Cc2cncc3ccccc23)cc(OC2CCC(=O)N2)c1

ERI-UCB-ce40166b-10
0.321

View
O=C(Cc1ccc(F)cc1)Nc1cccnc1

MAK-UNK-a7b37c5e-5
0.321

View
O=C(Cc1cncc2ccccc12)Nc1cccc(Oc2cccnc2)c1

ERI-UCB-ce40166b-4
0.320

View
Cc1ccncc1NC(=O)C(C)c1cc(Cl)cc(OC2CC(=O)N2)c1

TRY-UNI-2eddb1ff-8
0.320

View
CCN(C(=O)Nc1cnccc1C)c1cc(Cl)cc(OC2CC(=O)N2)c1

MAR-UCB-ad2ff052-2
0.317

View
O=C(Cc1cncc2ccccc12)Nc1cccc(Oc2cccc(=O)[nH]2)c1

ERI-UCB-ce40166b-3
0.317

View
O=C(Cc1cncnc1)NC1CCCNC1

MAK-UNK-748f8b7a-7
0.316

View
CC(O)C(NC(=O)Cc1cncnc1)N(C)C

MAK-UNK-748f8b7a-12
0.316

View
Cn1cc(NC(=O)Cc2cc(Cl)cc(OC3CC(=O)N3)c2)c2ccccc2c1=O

MAT-POS-3b92565d-9
0.314

View
O=C(Cc1cc(Cl)cc(OC2CC(=O)N2)c1)Nc1cc(=O)[nH]c2ccccc12

MAT-POS-3b92565d-6
0.314

View
C=CC(=O)N(C(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1)c1cccnc1

TRY-UNI-69298daf-6
0.314

View
O=C(Cc1cccnc1Br)Nc1cccc(OCCn2cncn2)c1

BAR-COM-4e090d3a-35
0.313

View
O=C(Cc1cncnc1)NCCOC1CNC1

MAK-UNK-748f8b7a-4
0.312

View
O=C(Cc1cncc(Cl)c1)Nc1cccnc1

DAR-DIA-23aa0b97-16
0.312

View
O=C1CC(c2cccc(NC(=O)c3cncnc3)c2)CC(=O)N1

MAR-TRE-9d18ae8c-2
0.310

View
Cc1ccncc1CC(=O)Nc1cccc(Cl)c1

EDJ-MED-49816e9b-1
0.310

View
Cc1ccncc1NC(=O)C(CCc1ccccc1)c1cc(Cl)cc(OC2CC(=O)N2)c1

ALP-POS-3fc1724e-6
0.309

View
O=C(Cc1cccc(Cl)c1)Nc1cccnc1

EDG-MED-0da5ad92-2
0.309

View
Cn1cc(CC(=O)Nc2cccnc2)cn1

DAR-DIA-842b4336-11
0.309

View
COc1cccc(NC(=O)Cn2c(=O)c3cc(C4CC4)nn3c3ncccc32)c1

MAR-TRE-74c6519b-88
0.308

View
CNc1cccc(CC(=O)Nc2cnccc2C2CC2)c1

ALP-POS-95b75b4d-10
0.308

View
O=C1CC(Oc2cccc(OCCNC(=O)c3cc(=O)[nH]c4ccccc34)c2)N1

ERI-UCB-ce40166b-13
0.308

View
C#Cc1cccc(NC(=O)CNC(=O)c2cncnc2)c1

MAR-TRE-92684b97-89
0.307

View
O=C(CNC(=O)c1cncnc1)Nc1cccc(Br)c1

MAR-TRE-4f781e27-43
0.306

View
C=CC(=O)N(C(=O)Cc1cc(C#N)cc(OC2CC(=O)N2)c1)c1cnccc1C

TRY-UNI-69298daf-2
0.302

View
CC(NC(=O)c1cncnc1)c1cccc(NC(=O)Cc2ccccc2F)c1

MAR-TRE-9d18ae8c-62
0.300

View
O=C(Nc1cccc(CN2C(=O)CNC2=O)c1)c1cncnc1

MAR-TRE-66ac689e-31
0.300

View
CCCCC(C(=O)Nc1cnccc1C)c1cc(Cl)cc(OC2CC(=O)N2)c1

JAN-GHE-f4ca5a00-15
0.299

View
NS(=O)(=O)Cc1cccc(CC(=O)Nc2cccnc2)c1

CHA-MCP-85291e1d-5
0.299

View
O=C(Cc1ccccc1)Nc1cccnc1

SAN-PRS-52b81272-2
0.299

View
O=C1CC(Oc2cc(Cl)cc(CC(=O)Nn3cnc4ccccc43)c2)N1

MAT-POS-3b92565d-12
0.298

View
O=C1CC(Oc2cc(Cl)cc(CC(=O)Nn3cnc4ccccc43)c2)N1

MAT-POS-c478e61b-1
0.298

View
O=C(NCc1cccc(NC(=O)C2CCCC2)c1)c1cncnc1

MAR-TRE-9d18ae8c-34
0.298

View
COCC(=O)Nc1cccc(CNC(=O)c2cncnc2)c1

MAR-TRE-799db12b-33
0.297

View
CN(C)CC(=O)Nc1cccc(CNC(=O)c2cncnc2)c1

MAR-TRE-799db12b-24
0.297

View
O=C(CC1=CN=CN=C1)NC1=CC=CC(OC2CCCC2)=C1

0.686

View
CC1=CC(C)=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.662

View
CCC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.662

View
COC1=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=CC(OC)=C1

0.653

View
CCCC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.644

View
CC(C)(C)C1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.644

View
CCC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.636

View
CC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1C

0.635

View
COC1=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=CC(OC)=C1OC

0.635

View
CC1=CN=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)S1

0.635

View
CC1=NON=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.635

View
CCCC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.632

View
O=C(CCCC1=CC=CN=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.632

View
COC1=CC=CC(NC(=O)CC2=CN=CN=C2)=C1

0.627

View
CCOC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.627

View
CC(C)CC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.627

View
O=C(CC1=CC=CC(C2CC2)=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.627

View
COC1=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=CC(OC)=C1O

0.627

View
CCSC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.618

View
CCCCC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.618

View
O=C(CC1=CC=C(NC(=O)C2CC2)C=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.618

View
CC1=NC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)S1

0.618

View
CC1=CC=CC(C)=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.616

View
COC1=CC=CC(OC)=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.616

View
CCC1=CC=CC=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.616

View
CCC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)N=C1

0.615

View
COCCOC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.615

View
CC1=NN=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)S1

0.613

View
CC(C)OC1=CC=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.610

View
COCC1=CC=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.610

View
COC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1OC

0.610

View
O=C(CC1CC1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.609

View
CC(C)(C)OC1=CC=CC(NC(=O)CC2=CN=CN=C2)=C1

0.609

View
CC1=CN=CC(CCC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.608

View
CNC(=O)CCC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.606

View
CN1N=CC=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.605

View
CN1C=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=N1

0.605

View
O=C(CCC1=C[NH]N=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.605

View
O=C(CC1=CC=C(N2C=CC=C2)C=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.603

View
O=C(CC1=CC=C2CCCCC2=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.603

View
O=C(CC1=CC=C2OCCOC2=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.603

View
COC1=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=CC=C1C

0.603

View
O=C(CC1CC(=O)N1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.600

View
O=C(CC1=CC=C2COCC2=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.600

View
CC1=CC(C)=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C(C)=C1

0.600

View
CC(C)OC1=CC=CC(NC(=O)CC2=CN=CN=C2)=C1

0.600

View
CCOC1=CC=CC(NC(=O)CC2=CN=CN=C2)=C1

0.600

View
O=C(CC1=CN=CN=C1)NC1=CC(OC(F)F)=CC=C1

0.600

View
O=C(CC(F)(F)F)NC1=CC=CC(OC2CC(=O)N2)=C1

0.600

View
O=C(CCCCCC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1)NC1=CC=CC=C1

0.600

View
O=C(CC1=CN=CN=C1)NC1=CC(OC(F)(F)F)=CC=C1

0.600

View
CC(C)CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.600

View
CC(C)(C)CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.600

View
CC1=NOC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.597

View
CC1=N[NH]C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=N1

0.597

View
CC1=NC(C)=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)S1

0.597

View
O=C(CC1=CN=CN=C1)NC1=CC=CC(OC2=CC=NC=C2)=C1

0.597

View
O=C(CC1=CC=C2CCCC2=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.595

View
CN1N=CC(Cl)=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.595

View
CC(C)COC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.595

View
CCCOC1=CC=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.595

View
CCS(=O)(=O)C1=CC=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.595

View
O=C(CC1=CC=C(N2CCOCC2)C=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.593

View
O=C(CC1CCC1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.592

View
CC1=NN(C)C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.590

View
CC1=NC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=CS1

0.590

View
CC1=NC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C(C)S1

0.590

View
CC1=NOC(Cl)=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.590

View
CCC1=CSC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=N1

0.590

View
O=C(CC1=CC=CC(OCC2CC2)=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.588

View
O=C(CC1=CN=CN=C1)NC1=CC=CC(OC2=CC=CC=C2)=C1

0.583

View
CC1(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)CC1

0.583

View
CC1=NN(C)C(C)=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.582

View
CCOCCC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.581

View
O=C(CC1=CN=CN=C1)NC1=CC=CC(NC(=O)CC2=CN=CN=C2)=C1

0.581

View
O=C(CC1=CC(OCC(F)(F)F)=CC=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.580

View
COCCOC1=CC=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.580

View
COC1=CC=C(OC)C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.577

View
CC1=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C(C)=CC(N(C)C)=C1

0.577

View
C=CCOC1=CC(NC(=O)CC2=CN=CN=C2)=CC=C1

0.575

View
O=C(CC1CCCC1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.575

View
CCC1=NC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=CS1

0.575

View
CCCNC(=O)NC1=CC=C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=C1

0.573

View
O=C(CCCC1=CC=CC=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.571

View
COC1=CC=C(C)C=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.570

View
CCC1=N[NH]C(CC)=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.568

View
O=C(CC1=CC=C2OCCC2=C1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.566

View
O=C(CC1=CC=CC=C1)NCCC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.562

View
CC(C)(C)C1=NC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=CS1

0.561

View
CN1N=C(C2CC2)N=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.561

View
CCN1N=C(C)C(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1C

0.561

View
O=C(CC1=CSC(C2CC2)=N1)NC1=CC=CC(OC2CC(=O)N2)=C1

0.561

View
CC(C)=CCOC1=CC=CC(CC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)=C1

0.560

View
CCSC1=CC=CC=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.556

View
CN1N=C(C(F)(F)F)C=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.554

View
CCC1=NOC(CC)=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.554

View
CCC1=NN(C)C(CC)=C1CC(=O)NC1=CC=CC(OC2CC(=O)N2)=C1

0.548

View
O=C(COC1=CC=CC(NC(=O)CC2=CN=CN=C2)=C1)NC1=CC=CC=C1

0.545

View
CN1C=C(SCC(=O)NC2=CC=CC(OC3CC(=O)N3)=C2)C=N1

0.543

View
O=C(CC1=CN=CN=C1)NC1=CC=CC(OCCC2=CC=CC=C2)=C1

0.532

View

C(NC1C=CC=C(OC)C=1)(=O)CC1=CN=CN=C1

0.627

View
C(NC1C=CC=C(OC(C)C)C=1)(=O)CC1=CN=CN=C1

0.600

View
C(NC1=CC=CC(OC(F)F)=C1)(=O)CC1=CN=CN=C1

0.600

View
C(NC1=CC=CC(OC(F)(F)F)=C1)(=O)CC1=CN=CN=C1

0.600

View
C(NC1=CC=CC(OC2=CC=CC=C2)=C1)(=O)CC1=CN=CN=C1

0.583

View
C(NC1=CC=CC(OCC#N)=C1)(=O)CC1=CN=CN=C1

0.568

View
C(NC1C=CC=C(OCC#C)C=1)(=O)CC1=CN=CN=C1

0.568

View
C(NC1=CC=CC(OCC2=CC=CC=C2)=C1)(=O)CC1=CN=CN=C1

0.545

View
C(NC1=CC(OC)=C(C)C=C1)(=O)CC1=CN=CN=C1

0.447

View
C(NC1C=CC(F)=C(OC)C=1)(=O)CC1=CN=CN=C1

0.442

View
C(NC1C=CC(Br)=C(OC)C=1)(=O)CC1=CN=CN=C1

0.442

View
C(NC1=CC=C(OC2CCCCC2)C=C1)(=O)CC1=CN=CN=C1

0.438

View
C(NC1=CC=C(OC)C=C1)(=O)CC1=CN=CN=C1

0.431

View
C(NC1=CC=C(OCC)C=C1)(=O)CC1=CN=CN=C1

0.413

View
C(NC1=CC=C(OCC#C)C=C1)(=O)CC1=CN=CN=C1

0.397

View
C(NC1=CC=C(OCCCC)C=C1)(=O)CC1=CN=CN=C1

0.392

View
C(NC1=C(OCC)C=CC=C1)(=O)CC1=CN=CN=C1

0.385

View
C(NC1=C(C)C(OC)=CC=C1)(=O)CC1=CN=CN=C1

0.375

View
C(NC1=C(C)C=CC(OC)=C1)(=O)CC1=CN=CN=C1

0.358

View
C(NC1C(Cl)=CC=C(OC)C=1)(=O)CC1=CN=CN=C1

0.354

View


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