Molecule Details

CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1
Enamine Mcule MolPort Assayed
Molecular Properties
SMILES:
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1
MW: 346.08
Fraction sp3: 0.5
HBA: 4
HBD: 2
Rotatable Bonds: 4
TPSA: 86.71
cLogP: 2.05
Covalent Warhead:
Covalent Fragment:
Source
Enamine REAL: Z925903342
Mcule: MCULE-7146040291
MolPort: MolPort-002-126-111
Activity Data
Average Inhibition @ 20 µM - Fluorescence: -1.04798955
Average Inhibition @ 50 µM - Fluorescence: -2.697712
Relative Solubility @ 20 µM: 1.0
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-05-30
Synthesis Location: enamine
Shipped: 2020-06-24

catechol

Hetero_hetero

O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1O)C1CCN(C(=O)CCl)CC1

MAK-UNK-69bf97dd-5
0.419

View
O=C(Nc1ccccc1O)C1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-15
0.373

View
O=C(Nc1ccccc1O)C1CCN(C(=O)CCl)CC1

AAR-POS-0daf6b7e-6
0.373

View
O=C(Nc1cccnc1)C1CCN(S(=O)(=O)Cc2ccccc2Cl)CC1

MAR-TRE-3e4e6814-54
0.352

View
O=C(Cc1cccnc1)Nc1cc(Cl)ccc1O

BEN-DND-61647d40-18
0.351

View
NS(=O)(=O)c1ccc2cccc(NC(=O)C3CCN(C(=O)CCl)CC3)c2c1

MAK-UNK-69bf97dd-4
0.315

View
Cc1ccncc1NC(=O)C1CCN(Cc2cccc(Cl)c2)CC1

SAD-SAT-7d5528d9-7
0.315

View
O=C(Nc1ccccc1Br)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-16
0.312

View
O=C(Nc1ccc(Cl)cc1)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-20
0.312

View
Cc1n[nH]c(-c2ccc(C)c(NC(=O)C3CCN(C(=O)CCl)CC3)c2)n1

LON-WEI-120e5cf5-7
0.298

View
O=C(Nc1c[nH]c2ccc(Br)cc12)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-18
0.297

View
Cc1nc(-c2ccccc2)c(NC(=O)C(=O)N2CCC(C(=O)Nc3ccccc3O)CC2)s1

JAR-IMP-ed466bb3-10
0.293

View
O=C(Nc1cc(Cl)nc2ccccc12)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-14
0.292

View
O=C(Nc1ccccc1O)C1CCN(N2Cc3ccccc3C(c3ccccc3)C2)CC1

JAR-IMP-ed466bb3-17
0.292

View
CCc1ccc(NC(=O)C2CCN(C(=O)CCl)CC2)nc1

MAK-UNK-c97f7c8f-2
0.289

View
O=C(Nc1cccnc1)C1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1

KEI-TRE-d5e2018a-73
0.287

View
Cc1ccnc(NC(=O)C2CCN(C(=O)CCl)CC2)c1

LON-WEI-120e5cf5-13
0.286

View
O=C(Nc1ccccc1Cl)c1cc(Cl)ccc1O

CHR-SOS-7098f804-4
0.286

View
O=C(Nc1cccnc1)C1CCN(S(=O)(=O)c2cccnc2)CC1

MAR-TRE-d0525fbf-90
0.286

View
COc1ccc(S(=O)(=O)N2CCC(C(=O)NCc3cccnc3)CC2)cc1Cl

MAR-TRE-fd17a9b8-92
0.283

View
Cc1ccc(NC(=O)C2CCN(C(=O)CCl)CC2)nc1

MAK-UNK-c97f7c8f-1
0.280

View
Cc1cccc(CS(=O)(=O)N2CCC(C(N)=O)CC2)c1

JAG-UCB-ef2c0e8e-8
0.280

View
O=C(Nc1ccccc1C1COC1)C1CCN(C(=O)CCl)CC1

MAK-UNK-3d7e3904-3
0.279

View
O=C(Nc1ccccc1N1CCC1)C1CCN(C(=O)CCl)CC1

MAK-UNK-3d7e3904-2
0.279

View
O=C(Nc1ccccc1OC1CS(=O)(=O)C1)C1CCN(C(=O)CCl)CC1

MAK-UNK-a7992eb3-7
0.275

View
COc1ccc(S(=O)(=O)N2CCC(C(=O)NCC3CCCO3)CC2)cc1OC

MAR-TRE-fd17a9b8-2
0.274

View
CC(=O)c1ccc(NC(=O)C2CCN(C(=O)CCl)CC2)cc1

LON-WEI-120e5cf5-10
0.272

View
O=C(Nc1nnc(-c2ccccn2)o1)C1CCN(S(=O)(=O)c2ccc(F)cc2)CC1

DRA-CSI-7ec17797-18
0.270

View
CCNC(=O)c1cc(S(=O)(=O)N2CCC(C(N)=O)CC2)ccc1OC

MAR-TRE-fd17a9b8-50
0.270

View
O=C(Nc1ccccc1)C1CCN(CCCl)CC1

JAG-SYN-9c2cd0bd-9
0.269

View
Cc1n[nH]c(C)c1S(=O)(=O)N1CCC(C(=O)Nc2cccnc2)CC1

MAR-TRE-2fd8122f-19
0.269

View
Cc1noc(C)c1S(=O)(=O)N1CCC(C(=O)Nc2cccnc2)CC1

MAR-TRE-2fd8122f-29
0.269

View
Cc1cccnc1NC(=O)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-21
0.267

View
CC(=O)c1cccc(NC(=O)C2CCN(C(=O)CCl)CC2)c1

LON-WEI-120e5cf5-19
0.267

View
CNC(=O)c1cc(S(=O)(=O)N2CCC(C(=O)O)CC2)ccc1OC

MAR-TRE-fd17a9b8-100
0.267

View
CNC(=O)c1cc(S(=O)(=O)N2CCC(C(N)=O)CC2)ccc1OC

MAR-TRE-fd17a9b8-47
0.267

View
CN(C)c1nc(NC(=O)C2CCN(S(=O)(=O)c3ccc(F)cc3)CC2)nc2[nH]cnc12

DRA-CSI-7ec17797-4
0.267

View
O=C(Nc1ccccc1O)C1CCN(C(=O)CCC(=O)N2Cc3ccccc3C(c3ccccc3)C2)CC1

JAR-IMP-ed466bb3-12
0.267

View
O=C(Nc1cc(S(=O)(=O)N2CCOCC2)ccc1O)c1cncnc1

MAR-TRE-a9136c7b-65
0.267

View
O=C(Nc1ccccc1Oc1ccccn1)C1CCN(C(=O)CCl)CC1

MAK-UNK-a7992eb3-8
0.266

View
O=C(CCl)C1CCN(S(=O)(=O)c2cccc(F)c2)CC1

BEN-DND-76ad4ac9-6
0.266

View
O=C(Nc1ccccc1)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-15
0.266

View
O=C(Nc1ccccc1)C1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-86
0.266

View
COc1ccc(NC(=O)C2CCN(C(=O)CCl)CC2)cn1

AAR-POS-f650c5f2-4
0.264

View
COc1ccc(NC(=O)C2CCN(C(=O)CCl)CC2)cn1

AAR-POS-5507155c-2
0.264

View
COc1ccc(NC(=O)C2CCN(C(=O)CCl)CC2)cn1

LON-WEI-120e5cf5-1
0.264

View
COc1ccc(NC(=O)C2CCN(C(=O)CCl)CC2)cn1

LON-WEI-120e5cf5-17
0.264

View
CN1C(=O)C(C)(C)c2cc(S(=O)(=O)N3CCC(C(=O)Nc4cccnc4)CC3)ccc21

MAR-TRE-74c6519b-66
0.262

View
O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O

CHR-SOS-7098f804-1
0.262

View
Cc1ccc(S(=O)(=O)N2CCCCC2)cc1NC(=O)CCl

AHN-SAT-de2502ba-10
0.262

View
O=C(Nc1ccc([N+](=O)[O-])cc1Cl)c1cc(Cl)ccc1O

DRP-THE-fc26dc53-1
0.262

View
O=C(O)C1CCN(S(=O)(=O)c2c[nH]c3nccc(Cl)c23)CC1

MAR-TRE-3159af1a-50
0.261

View
O=C(Nc1ccccc1OC1CCN(Cc2ccccc2)CC1)C1CCN(C(=O)CCl)CC1

MED-COV-4280ac29-17
0.260

View
O=C(Nc1ccccc1)C1CCN(C(=O)CB(O)O)CC1

JAG-SYN-9c2cd0bd-8
0.259

View
COc1cc(NC(=O)C2CCN(C(=O)CCl)CC2)cc(OC)c1OC

LON-WEI-120e5cf5-3
0.259

View
COc1ccc(-c2nc3ccc(NC(=O)C4CCN(S(=O)(=O)Cc5ccccc5)CC4)cc3o2)c(Br)c1

DRA-CSI-3ab97369-4
0.259

View
CCCNC(=O)c1cc(S(=O)(=O)N2CCC(C(N)=O)CC2)ccc1OC

MAR-TRE-fd17a9b8-22
0.258

View
O=C(Nc1cccnc1)C1CCN(S(=O)(=O)c2ccc3c(c2)OCCCO3)CC1

MAR-TRE-2fd8122f-33
0.257

View
O=C(CCl)Nc1cc(S(=O)(=O)N2CCCC2)ccc1Cl

AHN-SAT-de2502ba-19
0.256

View
O=C(Nc1ccccc1O)C1CC2CC1CN2C(=O)CCl

MAK-UNK-3f402c2b-19
0.256

View
COc1ccc(-c2nc3ccc(NC(=O)C4CCN(S(=O)(=O)C5CC5)CC4)cc3o2)cc1

DRA-CSI-3ab97369-2
0.255

View
O=C(CCl)C1CCN(S(=O)(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-2
0.253

View
O=C(Nc1ccccc1)C1CCN(CB(O)O)CC1

JAG-SYN-9c2cd0bd-14
0.253

View
C#CC(=O)N1CCC(C(=O)Nc2ccccc2)CC1

JAG-SYN-9c2cd0bd-4
0.253

View
O=C(O)CNCC1CCCN(S(=O)(=O)/C=C/c2cccc(Cl)c2)C1

TAT-ENA-80bfd3e5-14
0.253

View
O=C(CCl)Nc1cc(S(=O)(=O)N2CCCCCC2)ccc1Cl

AHN-SAT-de2502ba-17
0.250

View
O=C(O)C1CCN(S(=O)(=O)c2c[nH]c3nccc(Cl)c23)C1

MAR-TRE-3159af1a-54
0.250

View
O=C(CCl)Nc1cc(S(=O)(=O)N2CCCCC2)ccc1Cl

AHN-SAT-de2502ba-18
0.250

View
COc1ccc(-c2nc3ccc(NC(=O)C4CCN(S(=O)(=O)c5ccc([N+](=O)[O-])cc5)CC4)cc3o2)cc1

DRA-CSI-3ab97369-3
0.250

View
CCn1cnc(S(=O)(=O)N2CCC[C@@H](C(=O)Nc3cccnc3)C2)c1

MAR-TRE-d0525fbf-54
0.248

View
Cc1[nH]c2ncnc(NC(=O)C3CCN(c4ccc(Cl)cn4)CC3)c2c1C

COM-UCB-8c7d23dc-16
0.248

View
O=C(Nc1cnccc1CO)C1CCOc2ccc(Cl)cc21

LON-WEI-0a73fcb8-7
0.247

View
O=C(Nc1cccnc1)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-11
0.247

View
CC(=O)/C=C/CN1CCC(C(=O)Nc2ccccc2)CC1

BEN-DND-031a96cc-5
0.247

View
O=C(Nc1ccc([N+](=O)[O-])cc1)c1cc(Cl)ccc1O

CHR-SOS-7098f804-3
0.247

View
CC(C)NC(=O)C1CCN(C(=O)CS(C)(=O)=O)CC1

VIK-SYN-9a3d118a-5
0.247

View
CC(NC(=O)CCl)c1cc(Cl)ccc1O

DAV-CRI-3edb475e-3
0.247

View
O=C(Nc1ccccc1OC1CCN(Cc2ccsc2)CC1)C1CCN(C(=O)CCl)CC1

MAK-UNK-a7992eb3-1
0.245

View
Cc1ccc(CN2CCC(C(=O)Nc3nnc(-c4ccccn4)o3)CC2)cc1

DRA-CSI-0a78d9ba-13
0.245

View
CCOC(=O)C1CCN(S(=O)(=O)c2cccc(C(=O)Nc3ccccc3)c2)CC1

MAR-TRE-fd17a9b8-56
0.245

View
O=C(Nc1cccnc1)C1CCN(S(=O)(=O)c2ccc(Oc3ccccc3)cc2)CC1

KEI-TRE-d5e2018a-38
0.245

View
CCn1cnnc1NC(=O)[C@H]1COc2cc(Cl)ccc2C1

JAG-UCB-c61058a9-4
0.245

View
O=C(Nc1cccnc1)[C@@H]1CCCN(S(=O)(=O)c2ccc(Cl)cc2)C1

MAR-TRE-04c86cea-17
0.245

View
O=C(CN1CCC(C(=O)Nc2ccc(Cl)nc2)CC1)Nc1ccc(F)cc1

MAR-TRE-7f7bb9f0-26
0.245

View
Cc1ccc(S(=O)(=O)N2CCOCC2)cc1NC(=O)CCl

AHN-SAT-de2502ba-9
0.244

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

MAR-TRE-6a44bbf2-32
0.244

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(F)c(F)c2)CC1

ABB-MCD-f8003a30-1
0.244

View
CC(=O)Nc1ccc(Cl)cc1CN1CCN(C(C)=O)CC1

KIM-UNI-7d12df64-3
0.244

View
CNC(=O)C1CCN(C(=O)CS(C)(=O)=O)CC1

VIK-SYN-bf9c9ac8-4
0.243

View
O=C(Nc1ccccc1OCC1(c2ccccn2)CCCC1)C1CCN(C(=O)CCl)CC1

MAK-UNK-a7992eb3-9
0.243

View
COCc1nc2c(NC(=O)C3CCCCC3)cccn2n1

MAR-TRE-04c86cea-82
0.242

View
CCOC(=O)C1CCN(S(=O)(=O)c2csc(C(=O)NC)c2)CC1

MAR-TRE-fd17a9b8-64
0.242

View
COc1ccc(S(=O)(=O)N2CCC(C(N)=O)CC2)cc1C(=O)NC(C)C

MAR-TRE-fd17a9b8-4
0.242

View
CC(C)(C)c1ccc(S(=O)(=O)CCNC(=O)C2CCN(C(=O)CCl)CC2)cc1

SAD-SAT-29425be4-6
0.242

View
O=C(Nc1cnccc1Cl)c1cc(Cl)ccc1O

CHR-SOS-7098f804-10
0.241

View
Cc1ccc(Cl)cc1NC(=O)CSCC#N

MAR-TRE-14ce9fd6-51
0.241

View
CC(C)(C)c1cccc(C(NC(=O)C2CCN(C(=O)CCl)CC2)c2ccc(Cl)cc2)c1

SAD-SAT-29425be4-25
0.240

View
O=C(Nc1cccc(-c2cc[nH]n2)c1)C1CCN(C(=O)CCl)CC1

LON-WEI-120e5cf5-2
0.240

View
O=C(Nc1nncn1C1CC1)C1COc2ccc(Cl)cc2C1

NAU-LAT-8502cac5-3
0.240

View
CS(=O)(=O)NCCc1ccc(Cl)cc1NC(=O)Nc1cccnc1

WAR-XCH-6eb0722e-4
0.240

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

1.000

View
CCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.837

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2O)CC1

0.833

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CCl)CC1

0.812

View
CCCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.804

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CBr)CC1

0.796

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2Cl)CC1

0.792

View
CCCCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.788

View
CCC(CC)CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.788

View
CCc1ccc(CS(=O)(=O)N2CCC(C(=O)Nc3cc(Cl)ccc3O)CC2)cc1

0.788

View
CS(=O)(=O)CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.784

View
CC(C)CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.784

View
CC(C)(C)CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.784

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CC2CC2)CC1

0.780

View
CCNS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.780

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2C)CC1

0.776

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(C)ccc2O)CC1

0.776

View
CCCCCCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.774

View
CCC(C)CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.774

View
CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.771

View
CC1(CS(=O)(=O)N2CCC(C(=O)Nc3cc(Cl)ccc3O)CC2)CC1

0.769

View
C=C(C)CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.769

View
CCS(=O)(=O)N1CCCC(C(=O)Nc2cc(Cl)ccc2O)C1

0.769

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2F)CC1

0.760

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2Br)CC1

0.760

View
CCc1ccc(O)c(NC(=O)C2CCN(S(=O)(=O)CC)CC2)c1

0.760

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(F)ccc2O)CC1

0.760

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Br)ccc2O)CC1

0.760

View
CCOCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.759

View
CCCC(C)CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.759

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2Cl)CC1

0.755

View
CCc1ccc(S(=O)(=O)N2CCC(C(=O)Nc3cc(Cl)ccc3O)CC2)cc1

0.755

View
Cc1ccc(CS(=O)(=O)N2CCC(C(=O)Nc3cc(Cl)ccc3O)CC2)cc1

0.755

View
COCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.755

View
CC(C)CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.755

View
CS(=O)(=O)CCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.755

View
CC(C)(C)CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.755

View
COC(C)CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.755

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1

0.750

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CCCCl)CC1

0.750

View
CCN(CC)S(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.750

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)Cc2cccc(Cl)c2)CC1

0.750

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CC2CCCC2)CC1

0.750

View
CCCNS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.750

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CC2CCC2)CC1

0.750

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CCC2CC2)CC1

0.750

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2NC(C)=O)CC1

0.745

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2C(C)(C)C)CC1

0.745

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2NC(C)C)CC1

0.745

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2NC(C)=O)CC1

0.745

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)c(C)cc2O)CC1

0.745

View
CCS(=O)(=O)c1ccc(O)c(NC(=O)C2CCN(S(=O)(=O)CC)CC2)c1

0.745

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(S(C)(=O)=O)ccc2O)CC1

0.745

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(C(C)=O)ccc2O)CC1

0.745

View
Cc1ccccc1CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.741

View
Cc1ccc(CS(=O)(=O)N2CCC(C(=O)Nc3cc(Cl)ccc3O)CC2)cc1C

0.741

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2C)CC1

0.740

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)cc(Cl)c2O)CC1

0.740

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)c2ccc(Cl)cc2)CC1

0.740

View
CNS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.740

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CCCCCl)CC1

0.736

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CC2CCCCC2)CC1

0.736

View
C=CCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.736

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CCCF)CC1

0.736

View
C#CCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.736

View
CCN(C)S(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.736

View
NS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.735

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)N2CCC2)CC1

0.735

View
CCOC(=O)CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.732

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2OC)CC1

0.731

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2C(=O)NC)CC1

0.731

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2SC)CC1

0.731

View
CCCNc1ccc(Cl)cc1NC(=O)C1CCN(S(=O)(=O)CC)CC1

0.731

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2NC2CC2)CC1

0.731

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(OC)ccc2O)CC1

0.731

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(C(C)C)ccc2O)CC1

0.731

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(C(C)(C)C)ccc2O)CC1

0.731

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2N(C)C)CC1

0.731

View
CCC(=O)c1ccc(O)c(NC(=O)C2CCN(S(=O)(=O)CC)CC2)c1

0.731

View
CC(C)CCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.727

View
COCCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.727

View
CC1(CS(=O)(=O)N2CCC(C(=O)Nc3cc(Cl)ccc3O)CC2)CCCCC1

0.727

View
CC(C)(C)CCCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.727

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2F)CC1

0.725

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)cc2Br)CC1

0.725

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(O)c(Cl)c2)CC1

0.725

View
CC1CCN(S(=O)(=O)N2CCC(C(=O)Nc3cc(Cl)ccc3O)CC2)CC1

0.725

View
CN(C)S(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.725

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)c2cc(Cl)ccc2Cl)CC1

0.725

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)Cc2ccc(F)cc2)CC1

0.722

View
CCCN(CCC)S(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1

0.722

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)Cc2ccccc2Cl)CC1

0.722

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CCC(F)(F)F)CC1

0.722

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CCCCF)CC1

0.722

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)CCC2CCC2)CC1

0.722

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)N2CCCC2)CC1

0.720

View
O=C(Nc1cc(Cl)ccc1O)C1CCN(S(=O)(=O)C2CC2)CC1

0.720

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2C(F)(F)F)CC1

0.717

View
CCSc1ccc(Cl)cc1NC(=O)C1CCN(S(=O)(=O)CC)CC1

0.717

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(C#N)ccc2O)CC1

0.717

View
COc1ccccc1NC(=O)C1CCN(S(=O)(=O)Cc2ccc(Cl)cc2)CC1

0.198

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)c(Cl)cc2Cl)CC1

0.197

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cccc(Cl)c2F)CC1

0.197

View
CCCS(=O)(=O)N1CCC(C(=O)Nc2ccccc2OC)CC1

0.194

View
COc1ccc(Cl)cc1NC(=O)C1CCN(S(=O)(=O)Cc2ccccc2C)CC1

0.190

View
COc1ccc(Cl)cc1NC(=O)C1CCN(S(=O)(=O)N(C)C)CC1

0.190

View
CCCCS(=O)(=O)N1CCC(C(=O)Nc2cccc(Cl)c2)CC1

0.190

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cccc(Cl)c2Cl)CC1

0.190

View
CCCS(=O)(=O)N1CCC(C(=O)Nc2cc(C)ccc2O)CC1

0.188

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2C)CC1

0.188

View
COc1ccc(Cl)cc1NC(=O)C1CCN(S(=O)(=O)Cc2ccc(F)cc2)CC1

0.187

View
CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)cc(Cl)c2)CC1

0.186

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(C)c(Cl)c2)CC1

0.186

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cccc(Cl)c2C)CC1

0.184

View
CS(=O)(=O)N1CCC(C(=O)Nc2cccc(Cl)c2)CC1

0.182

View
CS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2Oc2ccccc2)CC1

0.180

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2Cl)CC1

0.177

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(OC)c(Cl)c2)CC1

0.174

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)c(N)c(Cl)c2)CC1

0.173

View
COc1ccc(Cl)cc1NC(=O)C1CCN(S(=O)(=O)Cc2cccc(C)c2)CC1

0.173

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccccc2OC)CC1

0.166

View
CCS(=O)(=O)N1CCC(C(=O)Nc2ccc(Cl)c(Cl)c2)CC1

0.161

View
CS(=O)(=O)N1CCC(C(=O)Nc2ccccc2O)CC1

0.160

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(C)ccc2O)CC1

0.160

View
COc1ccc(Cl)cc1NC(=O)C1CCN(S(=O)(=O)Cc2ccc(C)cc2)CC1

0.158

View
COc1ccc(Cl)cc1NC(=O)C1CCN(S(=O)(=O)Cc2ccccc2)CC1

0.150

View
CCCS(=O)(=O)N1CCC(C(=O)Nc2ccccc2O)CC1

0.144

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)cc(Cl)c2)CC1

0.138

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2Oc2ccccc2)CC1

0.138

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2Oc2ccc(Cl)cc2)CC1

0.138

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cccc(Cl)c2)CC1

0.134

View
COc1ccc(Cl)cc1NC(=O)C1CCN(S(C)(=O)=O)CC1

0.114

View
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2OC)CC1

0.070

View
C(NC1=C(OC)C=CC(Cl)=C1)(=O)C1CCN(S(C)(=O)=O)CC1

0.903

View
C(NC1=C(OC)C=CC(Cl)=C1)(=O)C1CCN(S(C2CC2)(=O)=O)CC1

0.865

View
C(NC1=CC=CC(Cl)=C1)(=O)C1CCN(S(C)(=O)=O)CC1

0.843

View
C(NC1=CC(Cl)=C(OC)C=C1)(=O)C1CCN(S(C)(=O)=O)CC1

0.840

View
C(NC1=C(OC)C=CC=C1)(=O)C1CCN(S(C)(=O)=O)CC1

0.823

View

Discussion: