Submission Details
Molecule(s):
NC(=O)Cn1cnc2c(nnn2-c2cccc(Cl)c2)c1=O
O=C1CC[C@H](C(=O)Nc2cccc(Br)c2)N1
Cc1cccc(NC(=O)Cn2c(=O)oc3ccccc32)c1
Cc1ccc(-n2ncc3c(=O)n(CC(N)=O)cnc32)cc1C
Nc1ncc(S(=O)(=O)NCc2cccc(Cl)c2)cn1
CCS(=O)(=O)N1CCC(C(=O)Nc2cc(Cl)ccc2O)CC1
Cn1cnnc1CNC(=O)Nc1cc(C(F)(F)F)c[nH]c1=O
Cc1cccc(CS(=O)(=O)N2CCC(C(N)=O)CC2)c1
Cc1ccc(C)c(NC(=O)[C@H]2CNC(=O)C2)c1
O=C1CC[C@@H](C(=O)Nc2cccc(Cl)c2)CN1
Design Rationale:
SureChEMBL pharmacophore search
Other Notes:
based on initial amino-pyridine non-covalent hits. Submitted by Matt Robinson on Jag's behalf