Molecular Properties | |
SMILES: | COc1ccc(Cl)cc1N1C(=O)CN(Cc2cc(=O)[nH]c3ccccc23)C1=O |
MW: | 397.08 |
Fraction sp3: | 0.15 |
HBA: | 4 |
HBD: | 1 |
Rotatable Bonds: | 4 |
TPSA: | 82.71 |
cLogP: | 3.16 |
Covalent Warhead: | ✗ |
Covalent Fragment: | ✗ |
Activity Data | |
IC50 (µM) - Fluorescence: | 99.5 |
IC50 (µM) - RapidFire: | 99.0 |
Order Status | |
Ordered: | 2020-06-25 |
Synthesis Location: | wuxi |
Shipped: | 2020-08-05 |
hydantoin
JAG-UCB-c37fbdcd-1
0.626
DAR-DIA-53551c05-21
0.389
MAT-POS-3b92565d-4
0.382
MAT-POS-e1b5ac6b-2
0.382
DAR-DIA-53551c05-18
0.380
DAR-DIA-53551c05-19
0.353
DAR-DIA-53551c05-16
0.352
EDJ-MED-d1cd9639-1
0.352
ALP-POS-05819dc4-1
0.339
EDJ-MED-edeb0d3a-1
0.336
BEN-DND-b89db3f2-5
0.336
ALP-POS-3fc1724e-4
0.328
DAR-DIA-b80f1cd7-1
0.327
BEN-DND-7e92b6ca-13
0.321
LON-WEI-1908424e-9
0.311
ALP-POS-fc6c627f-3
0.308
ALP-POS-75715966-3
0.307
MAR-TRE-92684b97-53
0.307
DAR-DIA-1a77c53a-1
0.301
JAN-GHE-82a280f8-1
0.297
DAR-DIA-1a77c53a-7
0.297
MAT-POS-916a2c5a-2
0.296
ERI-UCB-a0b0dbcb-9
0.296
BEN-DND-7e92b6ca-2
0.296
MAT-POS-590ac91e-43
0.295
MAT-POS-590ac91e-42
0.295
MAT-POS-590ac91e-54
0.294
DAR-DIA-1a77c53a-9
0.294
MAT-POS-3b92565d-5
0.294
MIC-UNK-b9827f26-4
0.293
ERI-UCB-a0b0dbcb-6
0.292
ERI-UCB-a0b0dbcb-11
0.289
ERI-UCB-d6de1f3c-8
0.289
DAR-DIA-1a77c53a-18
0.289
DAR-DIA-1a77c53a-20
0.289
ADA-UCB-6c2cb422-10
0.289
ADA-UCB-6c2cb422-11
0.289
ERI-UCB-a0b0dbcb-12
0.288
ERI-UCB-a0b0dbcb-2
0.287
DAR-DIA-1a77c53a-22
0.287
DAR-DIA-1a77c53a-23
0.285
MAR-UCB-f313ec4d-1
0.284
ADA-UCB-6c2cb422-8
0.283
DAR-DIA-8e329c92-4
0.283
ERI-UCB-a0b0dbcb-8
0.283
FAR-UNI-736b943a-5
0.281
AAR-POS-fca48359-8
0.281
ALP-POS-3fc1724e-1
0.281
MAT-POS-3b92565d-7
0.280
DAR-DIA-1a77c53a-3
0.280
DAR-DIA-1a77c53a-4
0.280
ALP-POS-3fc1724e-3
0.279
ROB-UNI-daaf9793-1
0.279
MAT-POS-e1b5ac6b-1
0.279
JAN-GHE-82a280f8-3
0.278
DAR-DIA-1a77c53a-11
0.278
DAR-DIA-1a77c53a-10
0.278
ERI-UCB-d6de1f3c-3
0.278
DAR-DIA-1a77c53a-16
0.277
NAU-LAT-56d5284e-8
0.277
ERI-UCB-d6de1f3c-1
0.277
MAT-POS-bbbbc21a-1
0.275
RAL-THA-2d450e86-29
0.275
MAT-POS-3b92565d-1
0.275
DAR-DIA-8e329c92-7
0.275
DAR-DIA-8e329c92-5
0.274
NAU-LAT-56d5284e-3
0.272
VLA-UCB-eb340134-1
0.272
ERI-UCB-a0b0dbcb-5
0.271
BEN-DND-7e92b6ca-10
0.271
KRI-MAR-d2e3ef86-5
0.271
NAU-LAT-56d5284e-5
0.270
NAU-LAT-56d5284e-7
0.270
MAR-UCB-f313ec4d-4
0.270
MAR-TRE-f5c2d31c-86
0.270
NAU-LAT-a5c7d7cb-7
0.270
MAT-POS-54c4bf04-4
0.270
ALP-POS-ddb41b15-4
0.268
MAT-UCB-70f7c0f7-4
0.268
VLA-UCB-eb340134-4
0.268
VLA-UCB-eb340134-3
0.267
ERI-UCB-d6de1f3c-4
0.266
JUL-TUD-06b2044f-112
0.265
MAK-UNK-df1a028e-3
0.264
DAR-DIA-8e329c92-6
0.263
NAU-LAT-56d5284e-6
0.263
NAU-LAT-56d5284e-4
0.263
KRI-MAR-d2e3ef86-6
0.263
NAU-LAT-56d5284e-1
0.261
KRI-MAR-d2e3ef86-13
0.261
BEN-DND-7e92b6ca-11
0.261
MAT-POS-3b92565d-6
0.261
MAT-UCB-93f6aed8-1
0.260
VLA-UCB-1dbca3b4-3
0.259
NAU-LAT-56d5284e-2
0.259
ERI-UCB-a0b0dbcb-1
0.259
BEN-DND-7e92b6ca-12
0.257
NAU-LAT-a5c7d7cb-9
0.257
MAR-UCB-f313ec4d-5
0.257
JAN-GHE-82a280f8-2
0.256