Submission Details

Molecule(s):
Nc1cccc(C2CN(C(=O)CCl)Cc3ccccc32)c1

NIR-THE-c331be7a-1

Nc1cccc(C2CN(C(=O)CCl)Cc3ccccc32)c1

N#Cc1cccc(C2CN(C(=O)CCl)Cc3ccccc32)c1

NIR-THE-c331be7a-2

N#Cc1cccc(C2CN(C(=O)CCl)Cc3ccccc32)c1

CC(=O)NCCc1c[nH]c2c(C3CN(C(=O)CCl)Cc4ccccc43)c(F)ccc12

NIR-THE-c331be7a-3

CC(=O)NCCc1c[nH]c2c(C3CN(C(=O)CCl)Cc4ccccc43)c(F)ccc12

NC(=O)Cc1ccccc1C1CN(C(=O)CCl)Cc2ccccc21

NIR-THE-c331be7a-4

NC(=O)Cc1ccccc1C1CN(C(=O)CCl)Cc2ccccc21

NS(=O)(=O)c1ccc2ccc(C3CN(C(=O)CCl)Cc4ccccc43)cc2c1

NIR-THE-c331be7a-5

NS(=O)(=O)c1ccc2ccc(C3CN(C(=O)CCl)Cc4ccccc43)cc2c1

Cc1cccc(C2CN(C(=O)CCl)Cc3ccccc32)c1

NIR-THE-c331be7a-6

Cc1cccc(C2CN(C(=O)CCl)Cc3ccccc32)c1


Design Rationale:

These are all based on merges of: - x1420 as a base covalent fragment with: - x0305, x0195, x0874 and x0104

Inspired By:
Discussion: