Molecule Details

O=C(Nc1cnccc1CO)[C@@H]1COc2ccc(Cl)cc21
Mcule Assayed
View on Fragalysis x10338
Molecular Properties
SMILES:
O=C(Nc1cnccc1CO)[C@@H]1COc2ccc(Cl)cc21
MW: 304.06
Fraction sp3: 0.2
HBA: 4
HBD: 2
Rotatable Bonds: 3
TPSA: 71.45
cLogP: 2.34
Covalent Warhead:
Covalent Fragment:
Source
Mcule: MCULE-7524608913
Activity Data
IC50 (µM) - Fluorescence: 42.3575881065483
IC50 (µM) - RapidFire: 18.387963478411
Trypsin IC50 (µM): 99.0
pIC50 (µM) - Fluorescence 4.37306877712543
Average Inhibition @ 20 µM - Fluorescence: 46.10042
Average Inhibition @ 50 µM - Fluorescence: 73.050635
Average Inhibition @ 50 µM - RapidFire: 58.622264305
Relative Solubility @ 20 µM: 1.01
Relative Solubility @ 100 µM: 1.0
Order Status
Ordered: 2020-05-17
Synthesis Location: enamine
Shipped: synthesis in progress
CS(=O)(=O)NCCc1ccccc1

AAR-POS-d2a4d1df-1

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O=C(Nc1cnccc1CO)C1CCOc2ccc(Cl)cc21

LON-WEI-0a73fcb8-7
0.711

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O=C(Nc1cncc2ccccc12)C1COc2ccc(Cl)cc21

MAT-POS-f7918075-2
0.573

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O=C(Nc1cncc2ccccc12)C1COc2ccc(Cl)cc21

MAT-POS-bbbbc21a-2
0.573

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O=C(Nc1cnnn1C1CC1)[C@@H]1COc2ccc(Cl)cc21

JAG-UCB-c61058a9-27
0.500

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CC(C)n1cc(NC(=O)[C@@H]2COc3ccc(Cl)cc32)nn1

JAG-UCB-c61058a9-14
0.488

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CC(C)n1ncnc1NC(=O)[C@@H]1COc2ccc(Cl)cc21

JAG-UCB-c61058a9-5
0.482

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Cc1ccncc1NC(=O)C1CCOc2ccc(Cl)cc21

BRU-CON-c4e3408a-1
0.471

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Cc1ccncc1NC(=O)C1CCOc2ccc(Cl)cc21

JAN-GHE-f4ca5a00-13
0.471

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Cc1ccncc1NC(=O)C1CCOc2ccc(Cl)cc21

DAR-DIA-6a508060-6
0.471

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Cc1ccncc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21

MAT-POS-b3e365b9-3
0.471

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Cc1ccncc1NC(=O)[C@@H]1CCOc2ccc(Cl)cc21

MAT-POS-b3e365b9-4
0.471

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O=C(Nc1nncn1C1CC1)C1COc2ccc(Cl)cc21

MIC-UNK-deda7a44-5
0.471

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O=C(Nc1nncn1C1CC1)[C@@H]1COc2ccc(Cl)cc21

JAG-UCB-c61058a9-18
0.471

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O=C(Nc1nncn1C1CC1)C1COc2ccc(Cl)cc21

NAU-LAT-8502cac5-2
0.471

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O=C(Nc1cnccc1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

ERI-UCB-9c7ec71b-2
0.461

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Cc1nnc(NC(=O)C2COc3ccc(Cl)cc32)n1C1CC1

JAG-UCB-47403a7c-1
0.455

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Cc1nnc(NC(=O)[C@@H]2COc3ccc(Cl)cc32)n1C1CC1

JAG-UCB-c61058a9-1
0.455

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Cn1c(NC(=O)[C@@H]2COc3ccc(Cl)cc32)nnc1C1CC1

JAG-UCB-c61058a9-3
0.455

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O=C(Nc1nncn1-c1ccccc1)C1COc2ccc(Cl)cc21

NAU-LAT-8502cac5-6
0.435

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O=C(Nc1cnccc1-n1cccn1)C1CCOc2ccc(Cl)cc21

NAU-LAT-b7d8c353-5
0.423

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CN1CCN(c2ccncc2NC(=O)C2CCOc3ccc(Cl)cc32)CC1

NAU-LAT-b7d8c353-6
0.410

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O=C(Nc1cnoc1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

JAG-UCB-c61058a9-7
0.402

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O=C(Nc1cncc2ccccc12)C1CCOc2ccc(Cl)cc21

VLA-UCB-1dbca3b4-15
0.400

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NCc1cccc2c(NC(=O)C3CCOc4ccc(Cl)cc43)cncc12

NAU-LAT-b7d8c353-8
0.400

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O=C(Nc1cncc2ccccc12)[C@H]1CCOc2ccc(Cl)cc21

MAT-POS-b3e365b9-2
0.400

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O=C(Nc1cncc2ccccc12)[C@@H]1CCOc2ccc(Cl)cc21

MAT-POS-b3e365b9-1
0.400

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O=C(Nc1cncc2ccccc12)C1CCOc2ccc(Cl)cc21

MAT-POS-f7918075-1
0.400

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O=C(Nc1cnoc1C1CCC1)[C@@H]1CCOc2ccc(Cl)cc21

JAG-UCB-c61058a9-11
0.394

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O=C(Nc1ncc(CO)o1)[C@@H]1CCOc2ccc(Cl)cc21

JAG-UCB-c61058a9-41
0.391

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O=C(CC12CCC(CC1)C2)Nc1cnccc1CO

CHA-KIN-ceadbd93-1
0.386

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O=C(Nc1oncc1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

JAG-UCB-c61058a9-6
0.380

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O=C(Nc1cncc2c1CCNC2)C1CCOc2ccc(Cl)cc21

NAU-LAT-b7d8c353-2
0.380

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CCn1cncc1NC(=O)C1CCOc2ccc(Cl)cc21

RAL-THA-3d7a794f-3
0.379

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O=C(Nc1cn[nH]c1-c1ccccc1)[C@@H]1CCOc2ccc(Cl)cc21

VLA-UCB-50c39ae8-13
0.374

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O=C(Nc1n[nH]c2ccncc12)C1CCOc2ccc(Cl)cc21

JAG-UCB-52b62a6f-16
0.374

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O=C(Nc1cn[nH]c1-c1ccccc1)[C@H]1CCOc2ccc(Cl)cc21

VLA-UCB-05e51b3f-20
0.374

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O=C(Nc1oncc1C1CCC1)[C@H]1CCOc2ccc(Cl)cc21

JAG-UCB-c61058a9-9
0.372

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Cn1cncc1NC(=O)C1CCOc2ccc(Cl)cc21

RAL-THA-3d7a794f-4
0.370

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O=C(Nc1cn[nH]c1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

VLA-UCB-53bdeed6-3
0.368

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NCc1cncc(NC(=O)C2CCOc3ccc(Cl)cc32)c1

NAU-LAT-b7d8c353-1
0.368

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O=C(Nc1nnc(C2CC2)s1)[C@@H]1CCOc2ccc(Cl)cc21

JOH-UNI-16fcdf60-1
0.366

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CC(C)n1cncc1NC(=O)C1CCOc2ccc(Cl)cc21

RAL-THA-3d7a794f-2
0.365

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C[C@@H]1COc2ccc(Cl)cc2[C@H]1C(=O)Nc1cncc2ccccc12

MAT-POS-8a69d52e-6
0.364

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C[C@@H]1COc2ccc(Cl)cc2[C@@H]1C(=O)Nc1cncc2ccccc12

MAT-POS-8a69d52e-7
0.364

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CC1COc2ccc(Cl)cc2C1C(=O)Nc1cncc2ccccc12

MAT-POS-8a69d52e-4
0.364

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C[C@@H]1COc2ccc(Cl)cc2[C@H]1C(=O)Nc1cncc2ccccc12

BRU-THA-01b12488-1
0.364

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C[C@H]1COc2ccc(Cl)cc2[C@H]1C(=O)Nc1cncc2ccccc12

MAT-POS-8a69d52e-5
0.364

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C[C@H]1COc2ccc(Cl)cc2[C@@H]1C(=O)Nc1cncc2ccccc12

EDJ-MED-e4b030d8-11
0.364

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O=C(Nc1ncn(C2CC2)n1)C1CCOc2ccc(Cl)cc21

NAU-LAT-8502cac5-15
0.362

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O=C(Nc1nccn1C1CC1)C1CCOc2ccc(Cl)cc21

NAU-LAT-8502cac5-11
0.362

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O=C(CC1CCCCC1)Nc1cnccc1CO

CHA-KIN-ceadbd93-2
0.361

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C[C@@H]1C[C@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2O1

MAT-POS-8a69d52e-2
0.360

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C[C@H]1C[C@@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2O1

EDJ-MED-e4b030d8-3
0.360

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O=C(Nc1cccc2cn[nH]c12)C1CCOc2ccc(Cl)cc21

JAG-UCB-52b62a6f-13
0.360

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CC1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2O1

MAT-POS-8a69d52e-1
0.360

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C[C@H]1C[C@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2O1

MAT-POS-8a69d52e-3
0.360

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C[C@@H]1C[C@@H](C(=O)Nc2cncc3ccccc23)c2cc(Cl)ccc2O1

EDJ-MED-e4b030d8-2
0.360

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O=C(NC1CN2CCC1CC2)C1CCOc2ccc(Cl)cc21

MIC-UNK-13557a72-2
0.359

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O=C(Nc1cnnn1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

JAG-UCB-c61058a9-22
0.358

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O=C(Nc1cncn1C1CC1)C1CCOc2ccc(Cl)cc21

RAL-THA-3d7a794f-1
0.358

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O=C(Nc1cncn1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

PET-UNK-3e029fdc-1
0.358

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O=C(Nc1cnccc1CO)C(O)C1CCCCC1

CHA-KIN-ceadbd93-3
0.357

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Cc1cc2c(cc1C)[C@H](C(=O)Nc1cccnc1)CO2

JAG-UCB-a3ef7265-7
0.356

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N#CC1(CC(=O)Nc2cnccc2CO)CCCCC1

CHA-KIN-ceadbd93-5
0.356

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CCC[C@H]1COc2ccc(Cl)cc2[C@@H]1C(=O)Nc1cncc2ccccc12

EDJ-MED-e4b030d8-6
0.356

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O=C1COc2ccc(Cl)cc2C1C(=O)Nc1cncc2ccccc12

VLA-UCB-1dbca3b4-16
0.354

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O=C(Nc1n[nH]c2ccccc12)C1CCOc2ccc(Cl)cc21

JAG-UCB-52b62a6f-17
0.354

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O=C(Cc1cncc2ccccc12)C1CCOc2ccc(Cl)cc21

DAR-DIA-6a508060-1
0.354

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NCCc1n[nH]c(NC(=O)[C@@H]2CCOc3ccc(Cl)cc32)n1

ROB-UNI-569bc02e-3
0.351

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Cc1ccncc1NC(=O)[C@@H]1CCc2ccc(Cl)cc21

ADA-UCB-6c2cb422-2
0.348

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CC(C)n1ncnc1NC(=O)C1CCOc2ccc(Cl)cc21

NAU-LAT-8502cac5-16
0.347

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O=C(Nc1nncn1CCO)C1CCOc2ccc(Cl)cc21

RAL-THA-b74298ba-4
0.343

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O=C(Nc1cnc2[nH]cccc1-2)[C@@H]1CCOc2ccc(Cl)cc21

ADA-UCB-b1b30a00-8
0.343

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O=C1NCCC1NC(=O)C1CCOc2ccc(Cl)cc21

MIC-UNK-42806bd5-4
0.341

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O=C(Nc1cnnn1C1CC1)[C@@H]1COc2ccc(Br)cc21

JAG-UCB-c61058a9-28
0.340

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CN1C(=O)CN=C1NC(=O)C1CCOc2ccc(Cl)cc21

NAU-LAT-8502cac5-10
0.340

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O=C(Nc1cc[nH]c(=O)c1)C1CCOc2ccc(Cl)cc21

NAU-LAT-b7d8c353-4
0.340

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Cn1cnnc1NC(=O)C1CCOc2ccc(Cl)cc21

RAL-THA-b74298ba-1
0.340

View
O=C(Nc1cc[nH]c(=O)c1)C1CCOc2ccc(Cl)cc21

BEN-DND-b89db3f2-2
0.340

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O=C(Nc1nncn1C1COC1)[C@H]1CCOc2ccc(Cl)cc21

EDG-MED-fe7487f8-8
0.340

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O=C(Nn1nncc1C1CC1)C1CCOc2ccc(Cl)cc21

JAN-GHE-f4ca5a00-23
0.340

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O=C(Oc1cncc2ccccc12)C1CCOc2ccc(Cl)cc21

DAR-DIA-6a508060-2
0.340

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CCn1cnnc1NC(=O)C1CCOc2ccc(Cl)cc21

RAL-THA-b74298ba-2
0.337

View
O=C(Nc1cc(=O)[nH]c2ccccc12)C1CCOc2ccc(Cl)cc21

JAG-UCB-c61058a9-45
0.337

View
O=C(Nc1cnc2n1CCOC2)C1CCOc2ccc(Cl)cc21

NAU-LAT-8502cac5-14
0.337

View
O=C(Nc1cc(=O)[nH]c2ccccc12)C1CCOc2ccc(Cl)cc21

NAU-LAT-b7d8c353-3
0.337

View
O=C(Nc1cc(=O)[nH]c2ccccc12)C1CCOc2ccc(Cl)cc21

BEN-DND-b89db3f2-1
0.337

View
O=C(Nc1[nH]nc2cccc(F)c12)C1CCOc2ccc(Cl)cc21

JAG-UCB-52b62a6f-5
0.337

View
O=C(Nc1cc(=O)[nH]c2ccccc12)C1CCOc2ccc(Cl)cc21

FRA-DIA-e29753f2-1
0.337

View
O=C(Nc1cc(=O)[nH]c2ccccc12)[C@@H]1CCOc2ccc(Cl)cc21

VLA-UCB-50c39ae8-11
0.337

View
O=C(Nc1cc(=O)[nH]c2ccccc12)[C@H]1CCOc2ccc(Cl)cc21

VLA-UCB-05e51b3f-18
0.337

View
O=C(Nc1nncn1C1CCNCC1)[C@@H]1CCOc2ccc(Cl)cc21

ADA-UCB-b1b30a00-7
0.333

View
O=C(Nc1nn[nH]c1C1CC1)[C@@H]1CCOc2ccc(Cl)cc21

VLA-UCB-53bdeed6-2
0.333

View
O=C(Nc1nncn1C1CC1)C1CCOc2ccc(Cl)cc21

JAG-UCB-a3ef7265-20
0.333

View
O=C(Nc1nnc2n1CCC2)C1CCOc2ccc(Cl)cc21

MIC-UNK-deda7a44-6
0.333

View
O=C1CC(NC(=O)C2CCOc3ccc(Cl)cc32)CN1

MIC-UNK-42806bd5-3
0.333

View
O=C(Nc1nncn1C1CC1O)C1CCOc2ccc(Cl)cc21

JAG-UCB-c61058a9-21
0.333

View
CC(C)n1cnnc1NC(=O)[C@H]1CCOc2ccc(Cl)cc21

EDG-MED-fe7487f8-9
0.333

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Cn1ccc(NC(=O)C2CCOc3ccc(Cl)cc32)cc1=O

NAU-LAT-b7d8c353-7
0.333

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CC(C)n1cnnc1NC(=O)C1CCOc2ccc(Cl)cc21

RAL-THA-b74298ba-3
0.333

View
O=C(Nc1cnccc1O)C1COc2ccc(Cl)cc21

0.769

View
Cc1ccncc1NC(=O)C1COc2ccc(Cl)cc21

0.736

View
O=C(Nc1ccncc1O)C1COc2ccc(Cl)cc21

0.722

View
CCc1cnccc1NC(=O)C1COc2ccc(Cl)cc21

0.714

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O=C(Nc1ccncc1F)C1COc2ccc(Cl)cc21

0.704

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Cc1cnccc1NC(=O)C1COc2ccc(Cl)cc21

0.704

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CC(=O)Nc1ccncc1NC(=O)C1COc2ccc(Cl)cc21

0.696

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CN1CCN(c2ccncc2NC(=O)C2COc3ccc(Cl)cc32)CC1

0.695

View
O=C(Nc1ccncc1Br)C1COc2ccc(Cl)cc21

0.691

View
O=C(Nc1ccncc1I)C1COc2ccc(Cl)cc21

0.691

View
O=C(Nc1cnccc1-c1ccccc1)C1COc2ccc(Cl)cc21

0.684

View
COc1ccncc1NC(=O)C1COc2ccc(Cl)cc21

0.684

View
CSc1ccncc1NC(=O)C1COc2ccc(Cl)cc21

0.684

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Cc1cc(C)c(NC(=O)C2COc3ccc(Cl)cc32)cc1CO

0.679

View
O=C(Nc1ccnc2ccncc12)C1COc2ccc(Cl)cc21

0.672

View
CC(C)(C)Oc1ccncc1NC(=O)C1COc2ccc(Cl)cc21

0.672

View
O=C(Nc1cnccn1)C1COc2ccc(Cl)cc21

0.667

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N#Cc1cnccc1NC(=O)C1COc2ccc(Cl)cc21

0.667

View
CC(=O)c1cnccc1NC(=O)C1COc2ccc(Cl)cc21

0.667

View
Cc1nccn1-c1ccncc1NC(=O)C1COc2ccc(Cl)cc21

0.667

View
Cc1cnccc1CNC(=O)C1COc2ccc(Cl)cc21

0.667

View
O=C(Nc1ccncc1N1CCOCC1)C1COc2ccc(Cl)cc21

0.661

View
O=C(Nc1cncc(Cl)c1Cl)C1COc2ccc(Cl)cc21

0.655

View
O=C(Nc1cccc2cnccc12)C1COc2ccc(Cl)cc21

0.644

View
O=C(Nc1cccc2ccncc12)C1COc2ccc(Cl)cc21

0.644

View
O=C(Nc1cncnc1N1CCCC1)C1COc2ccc(Cl)cc21

0.644

View
CCc1cnccc1CNC(=O)C1COc2ccc(Cl)cc21

0.644

View
O=C(Nc1ccncc1)C1COc2ccc(Cl)cc21

0.642

View
O=C(Nc1cnccc1Oc1ccccc1)C1COc2ccc(Cl)cc21

0.639

View
O=C(Nc1cnccc1-n1cccn1)C1COc2ccc(Cl)cc21

0.639

View
Cc1ccncc1CNC(=O)C1COc2ccc(Cl)cc21

0.638

View
O=C(Nc1cccnc1Cl)C1COc2ccc(Cl)cc21

0.636

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CC(C)C(=O)c1cnccc1NC(=O)C1COc2ccc(Cl)cc21

0.633

View
O=C(Nc1cncc(Cl)c1Br)C1COc2ccc(Cl)cc21

0.632

View
O=C(Nc1cccnc1O)C1COc2ccc(Cl)cc21

0.632

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Cc1cnn(-c2ccncc2NC(=O)C2COc3ccc(Cl)cc32)c1

0.629

View
O=C(Nc1cnccc1-c1cccc(F)c1)C1COc2ccc(Cl)cc21

0.629

View
O=C(NCC(CO)Cc1ccncc1Cl)C1COc2ccc(Cl)cc21

0.629

View
O=C(Nc1nccc2ccncc12)C1COc2ccc(Cl)cc21

0.627

View
O=C(Nc1cccnc1)C1COc2ccc(Cl)cc21

0.625

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COc1cnccc1CNC(=O)C1COc2ccc(Cl)cc21

0.623

View
Cc1c(NC(=O)C2COc3ccc(Cl)cc32)cnn1CCO

0.623

View
Cc1ccc(CO)cc1NC(=O)C1COc2ccc(Cl)cc21

0.621

View
O=C(Nc1cncc2ccccc12)C1COc2ccc(Cl)cc21

0.621

View
O=C(Nc1ccsc1Cl)C1COc2ccc(Cl)cc21

0.618

View
CN(C)c1ncncc1NC(=O)C1COc2ccc(Cl)cc21

0.617

View
CC(C)c1ncncc1NC(=O)C1COc2ccc(Cl)cc21

0.617

View
Cc1cnccc1CCNC(=O)C1COc2ccc(Cl)cc21

0.617

View
Cc1cc(Cl)ncc1NC(=O)C1COc2ccc(Cl)cc21

0.614

View
Cc1cc(NC(=O)C2COc3ccc(Cl)cc32)c(C)cn1

0.614

View
O=C(Nc1ccc(Cl)cc1O)C1COc2ccc(Cl)cc21

0.611

View
O=C(Nc1cc(Cl)ccc1O)C1COc2ccc(Cl)cc21

0.611

View
CCc1cc(O)ccc1NC(=O)C1COc2ccc(Cl)cc21

0.610

View
Cc1cnncc1NC(=O)C1COc2ccc(Cl)cc21

0.607

View
O=C(NCc1ccncc1)C1COc2ccc(Cl)cc21

0.607

View
O=C(NCc1ccccc1CO)C1COc2ccc(Cl)cc21

0.607

View
COc1ccncc1CNC(=O)C1COc2ccc(Cl)cc21

0.607

View
O=C(Nc1cc(Cl)ccc1Cl)C1COc2ccc(Cl)cc21

0.604

View
Cc1cc(Cl)ccc1NC(=O)C1COc2ccc(Cl)cc21

0.604

View
O=C(Nc1ccc(Cl)cc1Cl)C1COc2ccc(Cl)cc21

0.604

View
O=C(Nc1cc(Br)cnc1Cl)C1COc2ccc(Cl)cc21

0.603

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Cc1cnc(Cl)c(NC(=O)C2COc3ccc(Cl)cc32)c1

0.603

View
O=C(Nc1cc(Br)cnc1Br)C1COc2ccc(Cl)cc21

0.603

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Cc1ncccc1NC(=O)C1COc2ccc(Cl)cc21

0.603

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O=C(Nc1cnccc1O)C1COc2ccc(Br)cc21

0.603

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Cc1nccc(NC(=O)C2COc3ccc(Cl)cc32)c1Cl

0.603

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O=C(NNc1ccncc1Cl)C1COc2ccc(Cl)cc21

0.603

View
O=C(Nc1cncnc1-n1cccn1)C1COc2ccc(Cl)cc21

0.603

View
O=C(Nc1ncccn1)C1COc2ccc(Cl)cc21

0.600

View
O=C(Nc1ccc(Cl)cn1)C1COc2ccc(Cl)cc21

0.600

View
Cc1ccc(-c2ccncc2)cc1NC(=O)C1COc2ccc(Cl)cc21

0.600

View
O=C(Nc1ccc(N2CCOCC2)c2ccncc12)C1COc2ccc(Cl)cc21

0.600

View
O=C(Nc1cc(Cl)ccn1)C1COc2ccc(Cl)cc21

0.600

View
O=C(Nc1cncnc1)C1COc2ccc(Cl)cc21

0.600

View
Cc1ccc(-c2cccnc2)cc1NC(=O)C1COc2ccc(Cl)cc21

0.597

View
O=C(NCc1cnccc1C(F)(F)F)C1COc2ccc(Cl)cc21

0.597

View
CC(C)(C)c1ccncc1CNC(=O)C1COc2ccc(Cl)cc21

0.597

View
O=C(Nc1nccs1)C1COc2ccc(Cl)cc21

0.596

View
Cc1cc(O)ccc1NC(=O)C1COc2ccc(Cl)cc21

0.596

View
O=C(Nc1ccc(Cc2ccncc2)cc1)C1COc2ccc(Cl)cc21

0.593

View
N#CCc1ccccc1NC(=O)C1COc2ccc(Cl)cc21

0.593

View
O=C(Nc1ccnc2ccccc12)C1COc2ccc(Cl)cc21

0.593

View
CS(=O)(=O)Cc1ccccc1NC(=O)C1COc2ccc(Cl)cc21

0.593

View
Cc1cc(Br)ncc1NC(=O)C1COc2ccc(Cl)cc21

0.593

View
Cc1ncc(NC(=O)C2COc3ccc(Cl)cc32)c(C)n1

0.593

View
O=C(Nc1ccc(Br)nc1O)C1COc2ccc(Cl)cc21

0.593

View
O=C(NCc1cccnc1)C1COc2ccc(Cl)cc21

0.593

View
Cc1ccc(Cl)cc1NC(=O)C1COc2ccc(Cl)cc21

0.593

View
Cc1ccncc1CCNC(=O)C1COc2ccc(Cl)cc21

0.590

View
O=C(Nc1cccnc1N1CCCC1)C1COc2ccc(Cl)cc21

0.590

View
Cc1cncc(C)c1NC(=O)C1COc2ccc(Cl)cc21

0.589

View
O=C(Nc1ccccc1O)C1COc2ccc(Cl)cc21

0.589

View
O=C(Nc1ccc(Oc2cnccn2)cc1)C1COc2ccc(Cl)cc21

0.587

View
O=C(Nc1ccnc(OCCO)c1)C1COc2ccc(Cl)cc21

0.587

View
O=C(Nc1ccc(F)cn1)C1COc2ccc(Cl)cc21

0.586

View
NC(=O)c1sccc1NC(=O)C1COc2ccc(Cl)cc21

0.586

View
O=C(Nc1ccc(O)cc1F)C1COc2ccc(Cl)cc21

0.586

View
CCc1ccccc1NC(=O)C1COc2ccc(Cl)cc21

0.586

View
O=C(Nc1ccc(O)nc1)C1COc2ccc(Cl)cc21

0.586

View
O=C(Nc1cccnc1-c1ccccc1)C1COc2ccc(Cl)cc21

0.583

View

C(NC1=C(C)C=CN=C1)(=O)C1C2=C(C=CC=C2)OC1

0.888

View
C(NC1=CN=CC(Cl)=C1C)(=O)C1C2=C(C=CC=C2)OC1

0.865

View
C(NC1=C(C(OC)=O)C=CN=C1)(=O)C1C2=C(C=CC=C2)OC1

0.854

View
C(NC1=C(C)C(OC)=CN=C1)(=O)C1C2=C(C=CC=C2)OC1

0.827

View
C(NC1=CC=CN=C1)(=O)C1C2=C(C=CC=C2)OC1

0.820

View


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