Submission Details

JAG-UCB-a3ef7265
Molecule(s):
Cc1noc(C)c1CS(=O)(=O)Cc1cccc(Cl)c1

JAG-UCB-a3ef7265-1

Cc1noc(C)c1CS(=O)(=O)Cc1cccc(Cl)c1

Cn1cnnc1NC(=O)Cc1cccc(Cl)c1F

JAG-UCB-a3ef7265-2

Cn1cnnc1NC(=O)Cc1cccc(Cl)c1F

3-aminopyridine-like Made Check Availability on Manifold View
O=C(Nc1cnccc1CO)[C@@H]1COc2ccc(Cl)cc21

JAG-UCB-a3ef7265-3

O=C(Nc1cnccc1CO)[C@@H]1COc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1nnc(NC(=O)Cc2cccc(Cl)c2F)n1C

JAG-UCB-a3ef7265-4

Cc1nnc(NC(=O)Cc2cccc(Cl)c2F)n1C

3-aminopyridine-like Made Check Availability on Manifold View
Cc1c(NC(=O)Cc2cccc(Cl)c2F)cnn1C

JAG-UCB-a3ef7265-5

Cc1c(NC(=O)Cc2cccc(Cl)c2F)cnn1C

3-aminopyridine-like Ordered Check Availability on Manifold View
Cc1cc(C)cc(CS(=O)(=O)N[C@@]23COC[C@@H]2C3)c1

JAG-UCB-a3ef7265-6

Cc1cc(C)cc(CS(=O)(=O)N[C@@]23COC[C@@H]2C3)c1

Cc1cc2c(cc1C)[C@H](C(=O)Nc1cccnc1)CO2

JAG-UCB-a3ef7265-7

Cc1cc2c(cc1C)[C@H](C(=O)Nc1cccnc1)CO2

3-aminopyridine-like Ordered Check Availability on Manifold View
COc1c(NC(=O)Cc2cccc(Cl)c2Cl)c(C)nn1C

JAG-UCB-a3ef7265-8

COc1c(NC(=O)Cc2cccc(Cl)c2Cl)c(C)nn1C

3-aminopyridine-like Made Check Availability on Manifold View
Cc1noc(C)c1NC(=O)Cc1cccc(Cl)c1Cl

JAG-UCB-a3ef7265-9

Cc1noc(C)c1NC(=O)Cc1cccc(Cl)c1Cl

3-aminopyridine-like Made Check Availability on Manifold View
Cc1nnc(NC(=O)Cc2cccc(Cl)c2F)s1

JAG-UCB-a3ef7265-10

Cc1nnc(NC(=O)Cc2cccc(Cl)c2F)s1

3-aminopyridine-like Made Check Availability on Manifold View
Cn1nnnc1NC(=O)Cc1csc(C(C)(C)C)n1

JAG-UCB-a3ef7265-11

Cn1nnnc1NC(=O)Cc1csc(C(C)(C)C)n1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1cc(C)cc(NC(=O)Cn2cncc2C)c1

JAG-UCB-a3ef7265-12

Cc1cc(C)cc(NC(=O)Cn2cncc2C)c1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1cc(C)cc(NC(=O)Cc2cnn(C)c2C)c1

JAG-UCB-a3ef7265-13

Cc1cc(C)cc(NC(=O)Cc2cnn(C)c2C)c1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1cccc(NC(=O)Cn2cncc2C)n1

JAG-UCB-a3ef7265-14

Cc1cccc(NC(=O)Cn2cncc2C)n1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1nnc(NC(=O)Cc2cccc(Cl)c2)n1C

JAG-UCB-a3ef7265-15

Cc1nnc(NC(=O)Cc2cccc(Cl)c2)n1C

3-aminopyridine-like Made Check Availability on Manifold View
Cc1ccc(C)c(N(C)C(=O)Cc2cnn(C)c2C)c1

JAG-UCB-a3ef7265-16

Cc1ccc(C)c(N(C)C(=O)Cc2cnn(C)c2C)c1

3-aminopyridine-like Made Check Availability on Manifold View
Cn1cnnc1NC(=O)Cc1cccc(Cl)c1

JAG-UCB-a3ef7265-17

Cn1cnnc1NC(=O)Cc1cccc(Cl)c1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1cc(C)cc(CC(=O)Nc2nncn2C)c1

JAG-UCB-a3ef7265-18

Cc1cc(C)cc(CC(=O)Nc2nncn2C)c1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1nn(C(C)C)c(C)c1CC(=O)Nc1nncn1C1CC1

JAG-UCB-a3ef7265-19

Cc1nn(C(C)C)c(C)c1CC(=O)Nc1nncn1C1CC1

3-aminopyridine-like Made Check Availability on Manifold View
O=C(Nc1nncn1C1CC1)C1CCOc2ccc(Cl)cc21

JAG-UCB-a3ef7265-20

O=C(Nc1nncn1C1CC1)C1CCOc2ccc(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1noc([C@@H](C)S(=O)(=O)Cc2cccc(C(F)(F)F)c2)n1

JAG-UCB-a3ef7265-21

Cc1noc([C@@H](C)S(=O)(=O)Cc2cccc(C(F)(F)F)c2)n1

Cc1cc(NC(=O)Cn2cncc2C)cc(C)c1Cl

JAG-UCB-a3ef7265-22

Cc1cc(NC(=O)Cn2cncc2C)cc(C)c1Cl

3-aminopyridine-like Made Check Availability on Manifold View
CCc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)n1

JAG-UCB-a3ef7265-23

CCc1ccncc1NC(=O)Cc1cccc(C(F)(F)F)n1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1cc2c(cc1C)[C@H](C(=O)Nc1cncnc1-n1cccn1)CO2

JAG-UCB-a3ef7265-24

Cc1cc2c(cc1C)[C@H](C(=O)Nc1cncnc1-n1cccn1)CO2

3-aminopyridine-like Ordered Check Availability on Manifold View
Design Rationale:

pharmacophore search of Enamine based on amino-pyridine hits

Other Notes:

submitted by Matt Robinson, on behalf of Jag

Inspired By:
Discussion:

Contributor: Jag Heer, UCB - Fri, 15 May 2020 16:07:44 +0000