Submission Details

BEN-DND-93268d01
Molecule(s):
CC(C(=O)Nc1cncnc1)c1ccccc1

BEN-DND-93268d01-1

CC(C(=O)Nc1cncnc1)c1ccccc1

3-aminopyridine-like Assayed Check Availability on Manifold View
COCC(C(=O)Nc1cnccc1C)c1ccccc1

BEN-DND-93268d01-2

COCC(C(=O)Nc1cnccc1C)c1ccccc1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1NC(=O)C(CO)c1ccccc1

BEN-DND-93268d01-3

Cc1ccncc1NC(=O)C(CO)c1ccccc1

3-aminopyridine-like Ordered Check Availability on Manifold View
Cc1ccncc1NC(=O)CCc1ccccn1

BEN-DND-93268d01-4

Cc1ccncc1NC(=O)CCc1ccccn1

Cc1ccncc1NC(=O)CCc1ccc(F)cc1

BEN-DND-93268d01-5

Cc1ccncc1NC(=O)CCc1ccc(F)cc1

Cc1ccncc1NC(=O)CCc1cccc(F)c1

BEN-DND-93268d01-6

Cc1ccncc1NC(=O)CCc1cccc(F)c1

Cc1ccncc1NC(=O)CCc1ccccc1F

BEN-DND-93268d01-7

Cc1ccncc1NC(=O)CCc1ccccc1F

CC(=O)N1CCN(CC(=O)Nc2cnccc2C)CC1

BEN-DND-93268d01-8

CC(=O)N1CCN(CC(=O)Nc2cnccc2C)CC1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccncc1NC(=O)CN1CCN(C)CC1

BEN-DND-93268d01-9

Cc1ccncc1NC(=O)CN1CCN(C)CC1

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1NC(=O)CN1CCOCC1

BEN-DND-93268d01-10

Cc1ccncc1NC(=O)CN1CCOCC1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1ccncc1NC(=O)CN1CCCCC1

BEN-DND-93268d01-11

Cc1ccncc1NC(=O)CN1CCCCC1

3-aminopyridine-like Assayed Check Availability on Manifold View
Cc1ccncc1NC(=O)CN1CCCc2ccccc21

BEN-DND-93268d01-12

Cc1ccncc1NC(=O)CN1CCCc2ccccc21

3-aminopyridine-like Check Availability on Manifold View
Cc1ccncc1NC(=O)CC(C)(C)c1ccccc1

BEN-DND-93268d01-13

Cc1ccncc1NC(=O)CC(C)(C)c1ccccc1

Cc1ccncc1NC(=O)C(C)Cc1ccccc1

BEN-DND-93268d01-14

Cc1ccncc1NC(=O)C(C)Cc1ccccc1

CC(C(=O)Nc1cnccc1O)c1ccccc1

BEN-DND-93268d01-15

CC(C(=O)Nc1cnccc1O)c1ccccc1

3-aminopyridine-like Made Check Availability on Manifold View
Cc1c(O)cncc1NC(=O)C(C)c1ccccc1

BEN-DND-93268d01-16

Cc1c(O)cncc1NC(=O)C(C)c1ccccc1

3-aminopyridine-like Check Availability on Manifold View
Design Rationale:

Building structural data around confirmed non-covalent hitsTRY-UNI-714a760b-6 and JAN-GHE-83b26c96-4 : checked submissions list for compounds which were not available via commercial or Enamine sources, and designed new compounds around this - Note: not designed via docking or structure per se

Other Notes:

Componuds will be suggested for synthesis at DNDi Open Synthesis Network OSN

Inspired By:
Discussion:

Contributor: Benjamin Perry, DNDi - Thu, 14 May 2020 18:39:32 +0000