Molecule Details

O=C(NCCN1CCN(C(=O)CCl)CC1)c1cccc2ccccc12
piperazine-chloroacetamide Enamine Assayed
View on Fragalysis x10150
Molecular Properties
SMILES:
O=C(NCCN1CCN(C(=O)CCl)CC1)c1cccc2ccccc12
MW: 359.857
Fraction sp3: 0.37
HBA: 3
HBD: 1
Rotatable Bonds: 5
TPSA: 52.65
cLogP: 1.9526
Covalent Warhead: ✔️
Covalent Fragment: ✔️
Source
Enamine SCR: Z4444622185
Activity Data
Average Inhibition @ 20 µM - Fluorescence: 6.9680765
Average Inhibition @ 50 µM - Fluorescence: 4.690442
Average Inhibition @ 50 µM - RapidFire: 23.8018527196245
Order Status
Ordered: 2020-03-31
Synthesis Location: enamine
Shipped: 2020-05-26
O=C(CCl)N1CCN(C(=O)c2cccc3ccccc23)CC1

MAK-UNK-6ca90168-1
0.551

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O=C(NCCN1CCN(C(=O)CCl)CC1)c1ccccc1

STE-KUL-2e0d2e88-1
0.551

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O=C(NCCN1CC2CC1CN2C(=O)CCl)c1cccc2ccccc12

MAK-UNK-ec98eaf6-19
0.537

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O=C(NCCN1CCN(C(=O)CCl)CC1)c1cccnc1

STE-KUL-2e0d2e88-3
0.493

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O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

MED-COV-4280ac29-31
0.473

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O=C(CCl)N1CCN(Cc2cccc3ccccc23)CC1

AAR-POS-d2a4d1df-40
0.473

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O=C(CCl)N1CCN(Cc2scc3ccccc23)CC1

PAU-UNI-b2b6b158-1
0.436

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CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)NCCN1CCN(C(=O)CCl)CC1

NIM-UNI-ed9fc491-2
0.395

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O=C(CCl)N1CCN(Cc2cc(F)cc3ccccc23)CC1

DAR-DIA-fb20be43-2
0.395

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

DAR-DIA-fb20be43-8
0.390

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O=C(CCl)N1CCN(Cc2cc(Cl)cc3ccccc23)CC1

PAU-UNI-19862c28-1
0.390

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N#Cc1cc(CN2CCN(C(=O)CCl)CC2)c2ccccc2c1

DAR-DIA-fb20be43-6
0.388

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O=C(CCl)N1CCN(CCCc2ccccc2)CC1

MAK-UNK-15efde89-1
0.387

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COc1cc(CN2CCN(C(=O)CCl)CC2)c2ccccc2c1

DAR-DIA-fb20be43-7
0.376

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C=CC(=O)N1CCN(C(=O)c2cccc3ccccc23)CC1

MAK-UNK-6ca90168-2
0.372

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O=C(CCl)N1CCN(Cc2ccccc2)CC1

MAK-UNK-7c9d1431-24
0.371

View
O=C(Nc1nncn1C1CC1)c1cccc2ccccc12

ANT-OPE-bf404da3-1
0.369

View
CCNc1ccc(CNC(=O)CCCN2CCN(C(=O)CCl)CC2)cn1

MAK-UNK-af83ef51-31
0.363

View
CNC(=O)C(CCN1CCN(C(=O)CCl)CC1)Nc1ccccc1

MED-COV-dea4df70-1
0.357

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Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-4
0.355

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Cc1ccccc1CN1CCN(C(=O)CCl)CC1

MAK-UNK-7c9d1431-20
0.355

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O=C(CCl)N1CCN(C/C=C/c2ccccc2)CC1

SAD-SAT-65574d3f-1
0.355

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O=C(CCl)N1CCN(C/C=C/c2ccccc2)CC1

AHN-SAT-de2502ba-14
0.355

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Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

AAR-POS-d2a4d1df-24
0.355

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C#Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-5
0.354

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CCc1ccccc1NC(=O)CN1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-27
0.354

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O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cc3cccc4ccccc34)cc2)CC1

MED-COV-4280ac29-5
0.352

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CC(=O)NCCc1cn(C)c2c(CN3CCN(C(=O)CCl)CC3)cccc12

TAM-UNI-d1c3dd9f-20
0.348

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O=C(CCl)N1CCN(Cc2cccs2)CC1

LON-WEI-8f408cad-5
0.347

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O=C(CCl)N1CCN(Cc2ccc(Cl)s2)CC1

AAR-POS-0daf6b7e-2
0.347

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O=C(CCl)N1CCN(Cc2cccs2)CC1

AAR-POS-0daf6b7e-17
0.347

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O=C(CCl)N1CCN([C@@H](c2cccc3ccccc23)N2CCCOCC2)CC1

JOO-IND-3132366c-1
0.344

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O=C(CCl)N1CCN(Cc2ccc(-c3ccc4ccccc4c3CBr)s2)CC1

MAK-UNK-c74072e5-2
0.344

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O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

MED-COV-4280ac29-15
0.342

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O=C(CCl)N1CCN(Cc2cccc(Cl)c2)CC1

AAR-POS-d2a4d1df-35
0.342

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O=C(CCl)N1CCN(Cc2c(F)cccc2Cl)CC1

AHN-SAT-de2502ba-15
0.342

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NS(=O)(=O)c1ccc2cccc(CN3CCN(C(=O)CCl)CC3)c2c1

MIH-UNI-e573136b-4
0.341

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc(Cc3cccc4ccccc34)s2)CC1

MAK-UNK-e05327b2-8
0.340

View
C=Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-3
0.338

View
N#Cc1ccccc1C(=O)C(=O)N1CCN(C(=O)CCl)CC1

MAK-UNK-6ca90168-6
0.338

View
N#Cc1ccc(CNC(=O)N2CCN(C(=O)CCl)CC2)cc1

SWA-SYN-6423ea73-7
0.338

View
N#Cc1ccc(CNC(=O)N2CCN(C(=O)CCl)CC2)cc1

SWA-SYN-d2e6fa14-7
0.338

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CNC(=O)Cc1c(C)cccc1CN1CCN(C(=O)CCl)CC1

STE-UNK-13e151dd-1
0.337

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N#Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAT-POS-ee51dedd-1
0.333

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Cc1cccc(C)c1NC(=O)CN1CCN(C(=O)CCl)CC1

TAT-ENA-80bfd3e5-30
0.333

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O=C(CCl)N1CCN(Cc2cccc(CNC(=O)N3CCOCC3)c2)CC1

TAM-UNI-d1c3dd9f-12
0.333

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CNC(=O)C(NCCNC(C)=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-176ca439-2
0.330

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

MAR-TRE-6a44bbf2-8
0.329

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O=C(CCl)N1CCN(S(=O)(=O)c2ccccc2F)CC1

AAR-POS-d2a4d1df-34
0.329

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O=C(CCl)N1CCN(Cc2ccco2)CC1

MAK-UNK-7c9d1431-28
0.329

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N#Cc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-6ca90168-14
0.329

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O=C(CCl)N1CCN(Cc2ccc(Cl)cc2)CC1

MAK-UNK-7c9d1431-29
0.329

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CC(=O)NCCc1c[nH]c2c(CN3CCN(C(=O)CCl)CC3)cccc12

DUN-NEW-f8ce3686-24
0.326

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CCNc1ccccc1CN1CCN(C(=O)CCl)CC1

SEL-UNI-cd366922-6
0.325

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O=C(CCl)N1CCN(C(c2ccccc2)c2ccccc2)CC1

SIM-SYN-f15aaa3a-1
0.324

View
CC(=O)N1CCCc2cccc(CN3CCN(C(=O)CCl)CC3)c2C1

TAM-UNI-d1c3dd9f-13
0.322

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CN(C)Cc1cccc(CN2CCN(C(=O)CCl)CC2)c1

JOK-SYG-18591e8f-1
0.321

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O=C(CCl)N1CCN(Cc2ccc(CS(=O)(=O)F)cc2)CC1

JIA-UNI-93b03cae-1
0.321

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-d2e6fa14-1
0.321

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-1
0.321

View
O=C(CCl)N1CCN(c2ccccc2F)CC1

SAD-SAT-5b1897b2-10
0.320

View
NS(=O)(=O)c1ccc2c(CN3CCN(C(=O)CCl)CC3)cccc2c1

DAR-DIA-fb20be43-9
0.319

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CNC(=O)c1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-17
0.318

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CC(=O)Nc1ccc(C#N)cc1CN1CCN(C(=O)CCl)CC1

TAM-UNI-d1c3dd9f-18
0.318

View
O=C(CN1CCN(C(=O)CCl)CC1)Nc1cccc(F)c1

MAR-TRE-6a44bbf2-3
0.318

View
O=C(CNCc1c[nH]c2ccc(F)cc12)NCc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-176ca439-5
0.317

View
O=C(CNCc1c[nH]c2ccc(F)cc12)NCc1ccc(CN2CCN(C(=O)CCl)CC2)cc1

MAK-UNK-72b7ba6b-1
0.317

View
CNC(=O)c1cc2cccc(CN3CCN(C(=O)CCl)CC3)c2nc1N1CCN(C)CC1

BOG-INS-0b2b845a-1
0.317

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O=C(CCl)N1CCN(Cc2cc(O)ccc2O)CC1

NEH-REV-107bcf72-5
0.316

View
O=C(CCl)N1CCN(C(=O)Nc2ccccc2)CC1

AHN-SAT-de2502ba-7
0.316

View
COc1ccc(N2CCN(C(=O)CCl)CC2)cc1

AAR-POS-0daf6b7e-18
0.316

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

LON-WEI-8f408cad-7
0.316

View
O=C(CCl)N1CCN(c2cccc(Cl)c2)CC1

SAD-SAT-65574d3f-9
0.316

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

MAK-UNK-212f693e-8
0.316

View
O=C(CCl)N1CCN(Cc2ccsc2)CC1

AAR-POS-0daf6b7e-13
0.316

View
O=C(CCl)N1CCN(C(=O)c2ccccc2)CC1

MAK-UNK-987948f6-2
0.315

View
CNC(=O)C(CCN1CCN(C(=O)CCl)CC1)Nc1ccsc1

MAK-UNK-e4a48a85-2
0.315

View
Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

AAR-POS-d2a4d1df-41
0.313

View
Cc1ccccc1CN1CCCN(C(=O)CCl)CC1

TAT-ENA-80bfd3e5-20
0.313

View
Cc1ccc(NC(=O)CN2CCN(C(=O)CCl)CC2)cc1

MAR-TRE-6a44bbf2-12
0.312

View
O=C(CCl)N1CCCN(C(=O)c2c(F)cccc2F)CC1

BEN-DND-76ad4ac9-8
0.312

View
Cc1cccc(N2CCN(C(=O)CCl)CC2)c1

SAD-SAT-5b1897b2-4
0.312

View
O=C(CCl)N1CCN(Cc2cscc2Cl)CC1

SAD-SAT-bc31ec01-1
0.312

View
CC(C)(C)NC(=O)CN1CCN(C(=O)CCl)CC1

MAR-TRE-6a44bbf2-56
0.311

View
O=C(CCl)N1CCN(Cc2cnc(-c3ccccc3)nc2)CC1

MAK-UNK-af83ef51-1
0.310

View
N=S(=O)(CCN1CCN(C(=O)CCl)CC1)c1ccnc2cc(Cl)ccc12

ATU-SYN-3e3fbfe4-1
0.309

View
Cc1ccc(CN2CCN(C(=O)CCl)CC2)o1

MAR-LAB-ca4662a6-2
0.308

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

AAR-POS-0daf6b7e-12
0.308

View
CNCCSC(=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-cd94b63c-1
0.308

View
O=C(CCl)N1CCN(Oc2ccsc2)CC1

MAK-UNK-212f693e-9
0.308

View
O=C(CCl)N1CCN(Cc2ccc(Br)s2)CC1

JOH-UNI-27ac80fd-23
0.308

View
CNCCSC(=O)c1cccc(CN2CCN(C(=O)CCl)CC2)c1

MAK-UNK-176ca439-3
0.308

View
O=C(CCl)N1CCN(Cc2cc(Cl)cc(Cl)c2)CC1

PAU-UNI-8cdd41c7-1
0.307

View
NS(=O)(=O)CCc1ccccc1CN1CCN(C(=O)CCl)CC1

MIH-UNI-e573136b-5
0.306

View
O=C(CCl)N1CCN(S(=O)(=O)c2ccc3ccccc3c2)CC1

MAK-UNK-7c9d1431-3
0.306

View
O=C(CCl)N1CCN(C(=O)CCl)CC1

SAD-SAT-1b030f84-9
0.305

View
O=C(CCl)N1CCN(S(=O)(=O)Nc2ccccc2O)CC1

SWA-SYN-6423ea73-2
0.305

View
O=C(CN1CCN(C(=O)CCl)CC1)Nc1ccc(F)cc1

MAR-TRE-6a44bbf2-47
0.305

View
O=C(CCl)N1CCN(S(=O)(=O)Nc2ccccc2O)CC1

SWA-SYN-d2e6fa14-2
0.305

View
O=C1Cc2c(cccc2CN2CCN(C(=O)CCl)CC2)CCN1

TAM-UNI-d1c3dd9f-14
0.304

View
CC(=O)N1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.810

View
O=C(NCCN1CCN(C(=O)C2=CC=CC3=CC=CC=C23)CC1)C1=CC=CC2=CC=CC=C12

0.750

View
CN1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.750

View
CCN1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.750

View
O=C(NCCN1CCC1)C1=CC=CC2=CC=CC=C12

0.742

View
CC(C)(C)OC(=O)N1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.722

View
O=C(NCCN1CCCC1)C1=CC=CC2=CC=CC=C12

0.719

View
O=C(NCCN1CCCCC1)C1=CC=CC2=CC=CC=C12

0.697

View
O=C(NCCN1CCCCCC1)C1=CC=CC2=CC=CC=C12

0.697

View
O=C(NCCN1CCS(=O)(=O)CC1)C1=CC=CC2=CC=CC=C12

0.691

View
O=C(NCCN1CCNCC1)C1=CC=CC2=CC=CC=C12

0.687

View
O=C(NCCN1CCSCC1)C1=CC=CC2=CC=CC=C12

0.687

View
O=C(NCCN1CCN(C2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.686

View
O=C(NCCN1CCN(CC2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.686

View
CS(=O)(=O)N1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.686

View
O=C(NCCN1CCN(C(=O)C2CCCCC2)CC1)C1=CC=CC2=CC=CC=C12

0.680

View
O=C(NCCN1CCOCC1)C1=CC=CC2=CC=CC=C12

0.676

View
O=C(NCCN1CCC(O)CC1)C1=CC=CC2=CC=CC=C12

0.667

View
CC1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.657

View
O=C(NCCN1CC=CC1)C1=CC=CC2=CC=CC=C12

0.652

View
CN(C)C1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.648

View
O=C(NCCN1CCN(C2=CC=C(F)C=C2)CC1)C1=CC=CC2=CC=CC=C12

0.640

View
O=C(NCCN1CCN(C2=NC=CC=N2)CC1)C1=CC=CC2=CC=CC=C12

0.640

View
O=C(NCCN1CCN(C(=O)CCl)CC1)C1=CC=CC=C1F

0.632

View
COC1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.630

View
O=C(NCCN1CC2=CC=CC=C2C1)C1=CC=CC2=CC=CC=C12

0.623

View
O=C(NCCN1CCCOCC1)C1=CC=CC2=CC=CC=C12

0.622

View
O=C(NCCN1CCN(C(=O)CCC(=O)C2=CC=CC3=CC=CC=C23)CC1)C1=CC=CC=C1F

0.617

View
O=C(NCCN1CC=CCC1)C1=CC=CC2=CC=CC=C12

0.611

View
O=C(NCCN1CC[C@H](O)C1)C1=CC=CC2=CC=CC=C12

0.611

View
O=C(NCCN1CC[C@@H](O)C1)C1=CC=CC2=CC=CC=C12

0.611

View
CC1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)C1

0.603

View
O=C(NCCN1CCN(C(=O)C2=CC=CC3=CC=CC=C23)CC1)C1=CC=CC=C1F

0.603

View
CN1CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1(C)C

0.600

View
CC1=CCN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.595

View
CCN1CCN(C(=O)CNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.592

View
CN1CCN(CCCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.583

View
CCN1CCN(CCCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.583

View
O=C(NCCN1CCC2=CC=CC=C2C1)C1=CC=CC2=CC=CC=C12

0.579

View
O=C1CN(CCNC(=O)C2=CC=CC3=CC=CC=C23)CCN1

0.579

View
O=C(NCCCN1CCCC1)C1=CC=CC2=CC=CC=C12

0.577

View
CC(=O)N1CCN(C(=O)CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.575

View
CC(C)(C)OC(=O)N1CCN(CCCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.575

View
O=C(CNC(=O)C1=CC=CC2=CC=CC=C12)NCCN1CCCCC1

0.573

View
O=C(CNC(=O)C1=CC=CC2=CC=CC=C12)NCCN1CCCCCC1

0.573

View
CN1CCN(C(=O)CCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.568

View
CCN1CCN(CCCCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.568

View
CN1CCN(CCCCNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.568

View
O=C(NCCN1CCCC1)C1=CC=C(CNC(=O)C2=CC=CC3=CC=CC=C23)C=C1

0.562

View
O=C(NCCCN1CCCCCC1)C1=CC=CC2=CC=CC=C12

0.562

View
O=C(NCCCN1CCCCC1)C1=CC=CC2=CC=CC=C12

0.562

View
O=C(CNC(=O)C1=CC=CC2=CC=CC=C12)NCCN1CCOCC1

0.558

View
O=C(NCCC(=O)N1CCCC1)C1=CC=CC2=CC=CC=C12

0.556

View
CN1CCN(C(=O)CNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.556

View
O=C(NCCN1CCN(C(=O)CC2=CC=CC3=CC=CC=C23)CC1)C1=CC=CC=C1F

0.554

View
O=C(NCCCN1CCNCC1)C1=CC=CC2=CC=CC=C12

0.554

View
O=C(NCCN1CCN(C(=O)C2=CC=CC3=CC=CC=C23)CC1)C1CC1

0.551

View
O=C(CCl)N1CCN(C(=O)C2=CC=CC3=CC=CC=C23)CC1

0.551

View
O=C(NCC(=O)N1CCCC1)C1=CC=CC2=CC=CC=C12

0.551

View
O=C(NCCCN1CCOCC1)C1=CC=CC2=CC=CC=C12

0.547

View
O=C(NCCCCCN1CCCC1)C1=CC=CC2=CC=CC=C12

0.547

View
O=C(NCC(=O)N1CCN(CC2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.545

View
CN1CCN(CCNC(=O)NNC(=O)C2=CC=CC3=CC=CC=C23)CC1

0.545

View
CC(=O)N1CCN(CCNC(=O)C2=CC=CC3=CC(O)=CC=C23)CC1

0.545

View
O=C(NCCC(=O)N1CCCCC1)C1=CC=CC2=CC=CC=C12

0.541

View
O=C(NCCC(=O)N1CCCCCC1)C1=CC=CC2=CC=CC=C12

0.541

View
O=C(NCCCN1CCN(C2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.538

View
O=C(NCCCN1CCN(CC2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.538

View
CC(=O)N1CCN(CCNC(=O)C2=CC=CC3=CC(F)=CC=C23)CC1

0.538

View
O=C(NCC(=O)N1CCCCC1)C1=CC=CC2=CC=CC=C12

0.535

View
O=C(NCCC(=O)N1CCOCC1)C1=CC=CC2=CC=CC=C12

0.533

View
O=C(NCCCCCCCN1CCCC1)C1=CC=CC2=CC=CC=C12

0.532

View
O=C(NCCN1CCC2=CC=CC=C21)C1=CC=CC2=CC=CC=C12

0.532

View
O=C(NCCN1CCN(C(=O)COC2=CC=CC3=CC=CC=C23)CC1)C1=CC=CC=C1F

0.529

View
O=C(CC1=CC=CC2=CC=CC=C12)NCC(=O)N1CCN(CCNC(=O)C2=CC=CC=C2F)CC1

0.528

View
O=C(NCCCCN1CCN(C2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.525

View
O=C(NCCC(=O)N1CCN(C2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.519

View
O=C(NCCCC(=O)N1CCN(C2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.519

View
O=C(NCCN1CCN(CC2=CC=CC=C2)CC1)NNC(=O)C1=CC=CC2=CC=CC=C12

0.518

View
O=C(NCCN1CCCC2=CC=CC=C21)C1=CC=CC2=CC=CC=C12

0.512

View
O=C(NCC(=O)N1CCN(C2=CC=CC=C2)CC1)C1=CC=CC2=CC=CC=C12

0.506

View
O=C(NCCN1CCN(C2=CC=CC=C2)CC1)NNC(=O)C1=CC=CC2=CC=CC=C12

0.506

View
O=C(NCCCN1CCN(C2=NC=CC=N2)CC1)C1=CC=CC2=CC=CC=C12

0.506

View
O=C(NCCN1CCN(C(=O)NCC2=CC=CC3=CC=CC=C23)CC1)C1=CC=CC=C1F

0.506

View
O=C(NCCN1CCN(C(=O)NC2=CC=CC3=CC=CC=C23)CC1)C1=CC=CC=C1F

0.500

View
O=C(NCCN1CCNCC1)NNC(=O)C1=CC=CC2=CC=CC=C12

0.500

View
O=C(NCCN1CCOCC1)NNC(=O)C1=CC=CC2=CC=CC=C12

0.494

View
NCC(=O)N1CCN(CCNC(=O)C2=CC=CC=C2F)CC1

0.493

View
O=C(NCCC(=O)N1CCN(C2=CC=C(F)C=C2)CC1)C1=CC=CC2=CC=CC=C12

0.488

View
O=C(NCCN1CCN(CC2=CC=CC3=CC=CC=C23)CC1)C1=CC=CC=C1F

0.488

View
O=C(NCCN1CCN(C(=O)CC2=C(F)C=CC=C2F)CC1)C1=CC=CC=C1F

0.487

View
CC(=O)N1CCN(CCNC(=O)C2=CC=CC=C2Cl)CC1

0.486

View
O=C(NCC(=O)N1CCN(C2=CC=C(Cl)C=C2)CC1)C1=CC=CC2=CC=CC=C12

0.481

View
O=C(NCCN1CCN(C2=CC=C(F)C=C2)CC1)NNC(=O)C1=CC=CC2=CC=CC=C12

0.477

View
O=C(CCl)N1CCN(CC2=CC=CC3=CC=CC=C23)CC1

0.473

View
O=C(NCCN1CCN(C(=O)CC2=C(Cl)C=CC=C2Cl)CC1)C1=CC=CC=C1F

0.464

View
O=C(NCCN1CCN(C(=O)C2=CC=CC=C2Cl)CC1)C1=CC=CC=C1Cl

0.461

View
O=C(NCCN1CCN(C(=O)CC2=C(Cl)C=CC=C2F)CC1)C1=CC=CC=C1F

0.453

View
O=C(NCCN1CCN(C2=CC=CC=C2)CC1)N1CCN(C(=O)C2=CC=CC3=CC=CC=C23)CC1

0.449

View
O=C(NCCN1CCN(C(=O)C2=CC=CC=C2F)CC1)C1=CC=CC=C1F

0.442

View
O=C(NCCN1CCN(CC1)C(=O)c1cccc2ccccc12)c1cccc2ccccc12

0.750

View
NCCNC(=O)c1cccc2ccccc12

0.538

View
CN(C)CCNC(=O)c1cccc2ccccc12

0.515

View
Cl.O=C(NCCNC1CC1)c1cccc2ccccc12

0.514

View
Cl.CN(C)CCNC(=O)c1cccc2ccccc12

0.507

View
Cl.ClCC(=O)N1CCN(Cc2cccc3ccccc23)CC1

0.467

View
CC(CNC(=O)c1cccc2ccccc12)N1CCN(C)CC1

0.462

View
CCCN1CCN(CC1)C(=O)c1cccc2ccccc12

0.453

View
COCCN(C)CCNC(=O)c1cccc2ccccc12

0.449

View
O=C(N1CCN(CCC#N)CC1)c1cccc2ccccc12

0.430

View
O=C(N1CCN(CC1)C(=O)c1cccc2ccccc12)c1cccc2ccccc12

0.426

View
CCN1CCN(CC1)C(=O)c1cccc2ccccc12

0.419

View
CN1CCN(CC1)C(=O)c1cccc2ccccc12

0.405

View
CCNC(=O)CN1CCN(CC1)C(=O)c1cccc2ccccc12

0.402

View
O=C(N1CCN(Cc2ccccc2)CC1)c1cccc2ccccc12

0.400

View
Cl.O=C(N1CCNCC1)c1cccc2ccccc12

0.382

View
Cc1ccc(CN2CCN(CC2)C(=O)c2cccc3ccccc23)cc1

0.381

View
Cc1cccc(CN2CCN(CC2)C(=O)c2cccc3ccccc23)c1

0.372

View
OC(=O)C(O)=O.Cc1ccc(CN2CCN(CC2)C(=O)c2cccc3ccccc23)cc1

0.368

View
O=C(N1CCN(CC1)C(=O)c1cccc2ccccc12)c1ccccc1

0.367

View
Cc1ccccc1CN1CCN(CC1)C(=O)c1cccc2ccccc12

0.360

View
OC(=O)C(O)=O.CC(C)N1CCN(CC1)C(=O)c1cccc2ccccc12

0.358

View
Cc1ccc(cc1)C(=O)N1CCN(CC1)C(=O)c1cccc2ccccc12

0.354

View
ClCC(=O)N1CCN(CC1)C(=O)c1ccccc1

0.315

View
O=C(N1CCN(Cc2cccc3ccccc23)CC1)c1ccccc1

0.284

View
OC(=O)C(O)=O.O=C(N1CCN(Cc2cccc3ccccc23)CC1)c1ccccc1

0.278

View
Cl.ClCCN1CCN(CC1)C(=O)c1ccccc1

0.269

View
CCCN1CCN(CC1)C(=O)c1ccc2ccccc2c1

0.256

View
CCN1CCN(CC1)C(=O)c1ccc2ccccc2c1

0.235

View
O=C(N1CCN(Cc2ccccc2)CC1)c1ccc2ccccc2c1

0.220

View
O=C(N1CCN(Cc2ccc3ccccc3c2)CC1)c1ccccc1

0.217

View
CC(=O)N1CCN(CC1)C(=O)c1ccc2ccccc2c1

0.202

View
CN1CCN(CC1)C(=O)c1ccc2ccccc2c1

0.200

View
CC(C)N(CCNC(=O)c1ccc2ccccc2c1)C(C)C

0.200

View
O=CN1CCN(CC1)C(=O)c1ccc2ccccc2c1

0.184

View
O=C(N1CCN(CC1)C(=O)c1ccc2ccccc2c1)c1ccccc1

0.184

View
Cl.O=C(N1CCNCC1)c1ccc2ccccc2c1

0.184

View
C(NCCN1CCN(CC)CC1)(=O)C1C2C(=CC=CC=2)C=CC=1

0.750

View
C(NCCN1CCN(C)CC1)(=O)C1C2C(=CC=CC=2)C=CC=1

0.750

View
C(NCCN1CCN(CC2=CC=CC=C2)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.686

View
C(NCCN1CCN(CC)CC1)(=O)C1=C2C=CC=C(C)C2=CC=C1

0.456

View
C(N1CCN(CCC)CC1)(=O)C1C2C(=CC=CC=2)C=CC=1

0.453

View
C(N1CCN(CCN(C(C)C)C(C)C)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.450

View
C(NCCN1CCN(C)CC1)(=O)C1=C2C=CC=C(C)C2=CC=C1

0.443

View
C(N1CCN(CCCC)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.442

View
C(N1CCN(CCC#N)CC1)(=O)C1C2C(=CC=CC=2)C=CC=1

0.430

View
C(N1CCN(CC)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.419

View
C(N1CCN(C(C)=O)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.411

View
C(N(CC(N1CCN(C)CC1)=O)C)(=O)C1C2C(=CC=CC=2)C=CC=1

0.407

View
C(N1CCN(C)CC1)(=O)C1C2C(=CC=CC=2)C=CC=1

0.405

View
C(N(C)CCN1CCN(CC2=CC=CC=C2)CC1)(=O)C1C2C(=CC=CC=2)C=CC=1

0.395

View
C(N1CCN(CC#N)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.392

View
C(N1CCN(CC=C)CC1)(=O)C1C2C(=CC=CC=2)C=CC=1

0.392

View
C(N1CC(=O)N(C)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.392

View
C(N1CCN(C=O)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.382

View
C(N1CCN(C(C)C)CC1)(C1C2C(=CC=CC=2)C=CC=1)=O

0.372

View
C(N(CC)CCN(CC)CC)(C1C2C(=CC=CC=2)C=CC=1)=O

0.346

View


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