Submission Details

ALP-POS-fe871b40
Molecule(s):
N#Cc1cc(Cl)cc2c1OCCC2C(=O)Nc1cncc2ccccc12

ALP-POS-fe871b40-1
Duplicate of:
RAL-THA-05e671eb-20

N#Cc1cc(Cl)cc2c1OCCC2C(=O)Nc1cncc2ccccc12

Duplicate 3-aminopyridine-like Check Availability on Manifold View
N#Cc1cc(Cl)cc2c1NCCC2C(=O)Nc1cncc2ccccc12

ALP-POS-fe871b40-2

N#Cc1cc(Cl)cc2c1NCCC2C(=O)Nc1cncc2ccccc12

3-aminopyridine-like Assayed Check Availability on Manifold View
COC1(C(=O)Nc2cncc3ccccc23)CCOc2c(C#N)cc(Cl)cc21

ALP-POS-fe871b40-3

COC1(C(=O)Nc2cncc3ccccc23)CCOc2c(C#N)cc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
COC1(C(=O)Nc2cncc3ccccc23)CCNc2c(C#N)cc(Cl)cc21

ALP-POS-fe871b40-4

COC1(C(=O)Nc2cncc3ccccc23)CCNc2c(C#N)cc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CCOc2ncc(Cl)cc21

ALP-POS-fe871b40-5
Duplicate of:
RAL-THA-05e671eb-25

O=C(Nc1cncc2ccccc12)C1CCOc2ncc(Cl)cc21

Duplicate 3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CCNc2ncc(Cl)cc21

ALP-POS-fe871b40-6

O=C(Nc1cncc2ccccc12)C1CCNc2ncc(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
COC1(C(=O)Nc2cncc3ccccc23)CCOc2ncc(Cl)cc21

ALP-POS-fe871b40-7

COC1(C(=O)Nc2cncc3ccccc23)CCOc2ncc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
COC1(C(=O)Nc2cncc3ccccc23)CCNc2ncc(Cl)cc21

ALP-POS-fe871b40-8

COC1(C(=O)Nc2cncc3ccccc23)CCNc2ncc(Cl)cc21

3-aminopyridine-like Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CCOc2cc(F)c(Cl)cc21

ALP-POS-fe871b40-9
Duplicate of:
RAL-THA-05e671eb-10

O=C(Nc1cncc2ccccc12)C1CCOc2cc(F)c(Cl)cc21

Duplicate 3-aminopyridine-like Assayed Check Availability on Manifold View
O=C(Nc1cncc2ccccc12)C1CCNc2cc(F)c(Cl)cc21

ALP-POS-fe871b40-10
Duplicate of:
ALP-UNI-ba800595-2

O=C(Nc1cncc2ccccc12)C1CCNc2cc(F)c(Cl)cc21

Duplicate 3-aminopyridine-like Check Availability on Manifold View
COC1(C(=O)Nc2cncc3ccccc23)CCOc2cc(F)c(Cl)cc21

ALP-POS-fe871b40-11

COC1(C(=O)Nc2cncc3ccccc23)CCOc2cc(F)c(Cl)cc21

3-aminopyridine-like Assayed Check Availability on Manifold View
COC1(C(=O)Nc2cncc3ccccc23)CCNc2cc(F)c(Cl)cc21

ALP-POS-fe871b40-12

COC1(C(=O)Nc2cncc3ccccc23)CCNc2cc(F)c(Cl)cc21

3-aminopyridine-like Ordered Check Availability on Manifold View
N#Cc1cc(Cl)cc2c1NC(=O)CC2C(=O)Nc1cncc2ccccc12

ALP-POS-fe871b40-13

N#Cc1cc(Cl)cc2c1NC(=O)CC2C(=O)Nc1cncc2ccccc12

3-aminopyridine-like Check Availability on Manifold View
O=C1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)cnc2N1

ALP-POS-fe871b40-14

O=C1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)cnc2N1

3-aminopyridine-like Check Availability on Manifold View
O=C1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)c(F)cc2N1

ALP-POS-fe871b40-15

O=C1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)c(F)cc2N1

3-aminopyridine-like Check Availability on Manifold View
O=C1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)c(Cl)cc2N1

ALP-POS-fe871b40-16

O=C1CC(C(=O)Nc2cncc3ccccc23)c2cc(Cl)c(Cl)cc2N1

3-aminopyridine-like Assayed Check Availability on Manifold View
Design Rationale:

Combining P2 SAR trends

Discussion:

Contributor: Alpha Lee, PostEra - Thu, 28 Jan 2021 09:38:56 +0000